-
1
-
-
79958206937
-
Epstein lecture: Sirtuins, aging, and medicine
-
Guarente L, Franklin H: Epstein lecture: sirtuins, aging, and medicine. N Engl J Med 2011; 364: 2235-2244.
-
(2011)
N Engl J Med
, vol.364
, pp. 2235-2244
-
-
Guarente, L.1
Franklin, H.2
-
2
-
-
37549002891
-
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
-
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weissman S, Verdin E, Schwer B: Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol 2007; 27: 8807-8814.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8807-8814
-
-
Lombard, D.B.1
Alt, F.W.2
Cheng, H.L.3
Bunkenborg, J.4
Streeper, R.S.5
Mostoslavsky, R.6
Kim, J.7
Yancopoulos, G.8
Valenzuela, D.9
Murphy, A.10
Yang, Y.11
Chen, Y.12
Hirschey, M.D.13
Bronson, R.T.14
Haigis, M.15
Guarente, L.P.16
Farese Jr., R.V.17
Weissman, S.18
Verdin, E.19
Schwer, B.20
more..
-
3
-
-
84890966593
-
-
Cadenas E, Orrenius S, Packer L (eds): Mitochondrial Signaling in Health and Disease. London Taylor and Francis
-
Lombard DB, Tishkoff DX, Zwaans BM: Mitochondrial regulation by protein acetylation; in Cadenas E, Orrenius S, Packer L (eds): Mitochondrial Signaling in Health and Disease. London, Taylor and Francis, 2012, pp 269- 298.
-
(2012)
Mitochondrial Regulation by Protein Acetylation
, pp. 269-298
-
-
Lombard, D.B.1
Tishkoff, D.X.2
Zwaans, B.M.3
-
4
-
-
79959819034
-
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
-
Bell EL, Emerling BM, Ricoult SJ, Guarente L: SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene 2011; 30: 2986-2996.
-
(2011)
Oncogene
, vol.30
, pp. 2986-2996
-
-
Bell, E.L.1
Emerling, B.M.2
Ricoult, S.J.3
Guarente, L.4
-
5
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
-
Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB, Pandolfi PP, Haigis MC: SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell 2011; 19: 416- 428.
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
Pandolfi, P.P.11
Haigis, M.C.12
-
6
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, van der Meer R, Nguyen P, Savage J, Owens KM, Vassilopoulos A, Ozden O, Park SH, Singh KK, Abdulkadir SA, Spitz DR, Deng CX, Gius D: SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 2010; 17: 41-52.
-
(2010)
Cancer Cell
, vol.17
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
Bisht, K.S.4
Aykin-Burns, N.5
Pennington, J.D.6
Van Der Meer, R.7
Nguyen, P.8
Savage, J.9
Owens, K.M.10
Vassilopoulos, A.11
Ozden, O.12
Park, S.H.13
Singh, K.K.14
Abdulkadir, S.A.15
Spitz, D.R.16
Deng, C.X.17
Gius, D.18
-
7
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D: Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 2010; 12: 662-667.
-
(2010)
Cell Metab
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
8
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeuwenburgh C, Tanokura M, Denu JM, Prolla TA: Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010; 143: 802-812.
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeuwenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
9
-
-
78650248160
-
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
-
Tao R, Coleman MC, Pennington JD, Ozden O, Park SH, Jiang H, Kim HS, Flynn CR, Hill S, Hayes McDonald W, Olivier AK, Spitz DR, Gius D: Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol Cell 2010; 40: 893-904.
-
(2010)
Mol Cell
, vol.40
, pp. 893-904
-
-
Tao, R.1
Coleman, M.C.2
Pennington, J.D.3
Ozden, O.4
Park, S.H.5
Jiang, H.6
Kim, H.S.7
Flynn, C.R.8
Hill, S.9
Hayes McDonald, W.10
Olivier, A.K.11
Spitz, D.R.12
Gius, D.13
-
10
-
-
79953799195
-
Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer
-
Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, D'Silva NJ, Kapila YL: Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. Cancer 2011; 117: 1670-1678.
-
(2011)
Cancer
, vol.117
, pp. 1670-1678
-
-
Alhazzazi, T.Y.1
Kamarajan, P.2
Joo, N.3
Huang, J.Y.4
Verdin, E.5
D'Silva, N.J.6
Kapila, Y.L.7
-
11
-
-
84879119336
-
Role of SIRT3 in the regulation of redox balance during oral carcinogenesis
-
Chen IC, Chiang WF, Liu SY, Chen PF, Chiang HC: Role of SIRT3 in the regulation of redox balance during oral carcinogenesis. Mol Cancer 2013; 12: 68.
-
(2013)
Mol Cancer
, vol.12
, pp. 68
-
-
Chen, I.C.1
Chiang, W.F.2
Liu, S.Y.3
Chen, P.F.4
Chiang, H.C.5
-
12
-
-
84887625811
-
Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours
-
E-pub ahead of print
-
Aury-Landas J, Bougeard G, Castel H, Hernandez- Vargas H, Drouet A, Latouche JB, Schouft MT, Ferec C, Leroux D, Lasset C, Coupier I, Caron O, Herceg Z, Frebourg T, Flaman JM: Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours. Eur J Human Genet 2013, E-pub ahead of print.
-
(2013)
Eur J Human Genet
-
-
Aury-Landas, J.1
Bougeard, G.2
Castel, H.3
Hernandez- Vargas, H.4
Drouet, A.5
Latouche, J.B.6
Schouft, M.T.7
Ferec, C.8
Leroux, D.9
Lasset, C.10
Coupier, I.11
Caron, O.12
Herceg, Z.13
Frebourg, T.14
Flaman, J.M.15
-
13
-
-
82455212901
-
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
-
Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stancakova A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, Farese RV Jr, Kahn CR, Verdin E: SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell 2011; 44: 177- 190.
-
(2011)
Mol Cell
, vol.44
, pp. 177-190
-
-
Hirschey, M.D.1
Shimazu, T.2
Jing, E.3
Grueter, C.A.4
Collins, A.M.5
Aouizerat, B.6
Stancakova, A.7
Goetzman, E.8
Lam, M.M.9
Schwer, B.10
Stevens, R.D.11
Muehlbauer, M.J.12
Kakar, S.13
Bass, N.M.14
Kuusisto, J.15
Laakso, M.16
Alt, F.W.17
Newgard, C.B.18
Farese Jr., R.V.19
Kahn, C.R.20
Verdin, E.21
more..
-
14
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E: SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 2010; 464: 121- 125.
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
Stevens, R.D.11
Li, Y.12
Saha, A.K.13
Ruderman, N.B.14
Bain, J.R.15
Newgard, C.B.16
Farese Jr., R.V.17
Alt, F.W.18
Kahn, C.R.19
Verdin, E.20
more..
-
15
-
-
55749084738
-
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
-
Ahn BH, Kim HS, Song S, Lee IH, Liu J, Vassilopoulos A, Deng CX, Finkel T: A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci USA 2008; 105: 14447-14452.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14447-14452
-
-
Ahn, B.H.1
Kim, H.S.2
Song, S.3
Lee, I.H.4
Liu, J.5
Vassilopoulos, A.6
Deng, C.X.7
Finkel, T.8
-
16
-
-
77956173286
-
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity
-
Bao J, Scott I, Lu Z, Pang L, Dimond CC, Gius D, Sack MN: SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity. Free Radic Biol Med 2010; 49: 1230-1237.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 1230-1237
-
-
Bao, J.1
Scott, I.2
Lu, Z.3
Pang, L.4
Dimond, C.C.5
Gius, D.6
Sack, M.N.7
-
17
-
-
80051716282
-
Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity
-
Finley LW, Haas W, Desquiret-Dumas V, Wallace DC, Procaccio V, Gygi SP, Haigis MC: Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. PLoS One 2011; 6:e23295.
-
(2011)
PLoS One
, vol.6
-
-
Finley, L.W.1
Haas, W.2
Desquiret-Dumas, V.3
Wallace, D.C.4
Procaccio, V.5
Gygi, S.P.6
Haigis, M.C.7
-
18
-
-
75349111140
-
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
-
Cimen H, Han MJ, Yang Y, Tong Q, Koc H, Koc EC: Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 2010; 49: 304-311.
-
(2010)
Biochemistry
, vol.49
, pp. 304-311
-
-
Cimen, H.1
Han, M.J.2
Yang, Y.3
Tong, Q.4
Koc, H.5
Koc, E.C.6
-
19
-
-
78751513117
-
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation
-
Kendrick AA, Choudhury M, Rahman SM, McCurdy CE, Friederich M, Van Hove JL, Watson PA, Birdsey N, Bao J, Gius D, Sack MN, Jing E, Kahn CR, Friedman JE, Jonscher KR: Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. Biochem J 2011; 433: 505-514.
-
(2011)
Biochem J
, vol.433
, pp. 505-514
-
-
Kendrick, A.A.1
Choudhury, M.2
Rahman, S.M.3
McCurdy, C.E.4
Friederich, M.5
Van Hove, J.L.6
Watson, P.A.7
Birdsey, N.8
Bao, J.9
Gius, D.10
Sack, M.N.11
Jing, E.12
Kahn, C.R.13
Friedman, J.E.14
Jonscher, K.R.15
-
20
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR: Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci USA 2011; 108: 14608-14613.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14608-14613
-
-
Jing, E.1
Emanuelli, B.2
Hirschey, M.D.3
Boucher, J.4
Lee, K.Y.5
Lombard, D.6
Verdin, E.M.7
Kahn, C.R.8
-
21
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP: Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 2009; 119: 2758-2771.
-
(2009)
J Clin Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
22
-
-
79952266729
-
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
-
Hafner AV, Dai J, Gomes AP, Xiao CY, Palmeira CM, Rosenzweig A, Sinclair DA: Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging (Albany NY) 2010; 2: 914-923.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 914-923
-
-
Hafner, A.V.1
Dai, J.2
Gomes, A.P.3
Xiao, C.Y.4
Palmeira, C.M.5
Rosenzweig, A.6
Sinclair, D.A.7
-
23
-
-
77449120223
-
Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway
-
Pillai VB, Sundaresan NR, Kim G, Gupta M, Rajamohan SB, Pillai JB, Samant S, Ravindra PV, Isbatan A, Gupta MP: Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem 2010; 285: 3133- 3144.
-
(2010)
J Biol Chem
, vol.285
, pp. 3133-3144
-
-
Pillai, V.B.1
Sundaresan, N.R.2
Kim, G.3
Gupta, M.4
Rajamohan, S.B.5
Pillai, J.B.6
Samant, S.7
Ravindra, P.V.8
Isbatan, A.9
Gupta, M.P.10
-
24
-
-
77951176793
-
Sirtuin- 3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria
-
Shulga N, Wilson-Smith R, Pastorino JG: Sirtuin- 3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria. J Cell Sci 2010; 123: 894-902.
-
(2010)
J Cell Sci
, vol.123
, pp. 894-902
-
-
Shulga, N.1
Wilson-Smith, R.2
Pastorino, J.G.3
-
25
-
-
33746228121
-
Sirtuins in aging and age-related disease
-
Longo VD, Kennedy BK: Sirtuins in aging and age-related disease. Cell 2006; 126: 257-268.
-
(2006)
Cell
, vol.126
, pp. 257-268
-
-
Longo, V.D.1
Kennedy, B.K.2
-
26
-
-
78651468707
-
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
-
Hallows WC, Yu W, Smith BC, Devries MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM: Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell 2011; 41: 139-149.
-
(2011)
Mol Cell
, vol.41
, pp. 139-149
-
-
Hallows, W.C.1
Yu, W.2
Smith, B.C.3
Devries, M.K.4
Ellinger, J.J.5
Someya, S.6
Shortreed, M.R.7
Prolla, T.8
Markley, J.L.9
Smith, L.M.10
Zhao, S.11
Guan, K.L.12
Denu, J.M.13
-
27
-
-
84874238886
-
Sirt3 reverses aging-associated degeneration
-
Brown K, Xie S, Qiu X, Mohrin M, Shin J, Liu Y, Zhang D, Scadden DT, Chen D: Sirt3 reverses aging-associated degeneration. Cell Rep 2013; 3: 319-327.
-
(2013)
Cell Rep
, vol.3
, pp. 319-327
-
-
Brown, K.1
Xie, S.2
Qiu, X.3
Mohrin, M.4
Shin, J.5
Liu, Y.6
Zhang, D.7
Scadden, D.T.8
Chen, D.9
-
28
-
-
33746992118
-
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
-
Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y: Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell 2006; 23: 607-618.
-
(2006)
Mol Cell
, vol.23
, pp. 607-618
-
-
Kim, S.C.1
Sprung, R.2
Chen, Y.3
Xu, Y.4
Ball, H.5
Pei, J.6
Cheng, T.7
Kho, Y.8
Xiao, H.9
Xiao, L.10
Grishin, N.V.11
White, M.12
Yang, X.J.13
Zhao, Y.14
-
29
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA: AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 2012; 13: 251-262.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
30
-
-
79954517977
-
Structure of mammalian AMPK and its regulation by ADP
-
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ: Structure of mammalian AMPK and its regulation by ADP. Nature 2011; 472: 230-233.
-
(2011)
Nature
, vol.472
, pp. 230-233
-
-
Xiao, B.1
Sanders, M.J.2
Underwood, E.3
Heath, R.4
Mayer, F.V.5
Carmena, D.6
Jing, C.7
Walker, P.A.8
Eccleston, J.F.9
Haire, L.F.10
Saiu, P.11
Howell, S.A.12
Aasland, R.13
Martin, S.R.14
Carling, D.15
Gamblin, S.J.16
-
31
-
-
84863012559
-
Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK
-
Lin YY, Kiihl S, Suhail Y, Liu SY, Chou YH, Kuang Z, Lu JY, Khor CN, Lin CL, Bader JS, Irizarry R, Boeke JD: Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Nature 2012; 482: 251- 255.
-
(2012)
Nature
, vol.482
, pp. 251-255
-
-
Lin, Y.Y.1
Kiihl, S.2
Suhail, Y.3
Liu, S.Y.4
Chou, Y.H.5
Kuang, Z.6
Lu, J.Y.7
Khor, C.N.8
Lin, C.L.9
Bader, J.S.10
Irizarry, R.11
Boeke, J.D.12
-
32
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J, Handschin C, Spiegelman BM: Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 2005; 1: 361-370.
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
33
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jäger S, Handschin C, St-Pierre J, Spiegelman BM: AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci USA 2007; 104: 12017-12022.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12017-12022
-
-
Jäger, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
34
-
-
0038810035
-
An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
-
Handschin C, Rhee J, Lin J, Tarr PT, Spiegelman BM: An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci USA 2003; 100: 7111- 7116.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7111-7116
-
-
Handschin, C.1
Rhee, J.2
Lin, J.3
Tarr, P.T.4
Spiegelman, B.M.5
-
35
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J: AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 2009; 458: 1056-1060.
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
36
-
-
43049121395
-
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPKmediated regulation of Nampt
-
Fulco M, Cen Y, Zhao P, Hoffman EP, Mc- Burney MW, Sauve AA, Sartorelli V: Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPKmediated regulation of Nampt. Dev Cell 2008; 14: 661-673.
-
(2008)
Dev Cell
, vol.14
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
Hoffman, E.P.4
Mc- Burney, M.W.5
Sauve, A.A.6
Sartorelli, V.7
-
37
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ: Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 2011; 331: 456-461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
Asara, J.M.11
Fitzpatrick, J.12
Dillin, A.13
Viollet, B.14
Kundu, M.15
Hansen, M.16
Shaw, R.J.17
-
38
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13: 132-141.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
39
-
-
77952940043
-
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle
-
Palacios OM, Carmona JJ, Michan S, Chen KY, Manabe Y, Ward JL 3rd, Goodyear LJ, Tong Q: Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle. Aging (Albany NY) 2009; 1: 771-783.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 771-783
-
-
Palacios, O.M.1
Carmona, J.J.2
Michan, S.3
Chen, K.Y.4
Manabe, Y.5
Goodyear, L.J.6
Tong, Q.7
-
40
-
-
17144424946
-
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
-
Shi T, Wang F, Stieren E, Tong Q: SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 2005; 280: 13560-13567.
-
(2005)
J Biol Chem
, vol.280
, pp. 13560-13567
-
-
Shi, T.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
42
-
-
77955347446
-
Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
-
Kong X, Wang R, Xue Y, Liu X, Zhang H, Chen Y, Fang F, Chang Y: Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 2010; 5:e11707.
-
(2010)
PLoS One
, vol.5
-
-
Kong, X.1
Wang, R.2
Xue, Y.3
Liu, X.4
Zhang, H.5
Chen, Y.6
Fang, F.7
Chang, Y.8
-
43
-
-
51449083112
-
SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression
-
Jacobs KM, Pennington JD, Bisht KS, Aykin- Burns N, Kim HS, Mishra M, Sun L, Nguyen P, Ahn BH, Leclerc J, Deng CX, Spitz DR, Gius D: SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression. Int J Biol Sci 2008; 4: 291-299.
-
(2008)
Int J Biol Sci
, vol.4
, pp. 291-299
-
-
Jacobs, K.M.1
Pennington, J.D.2
Bisht, K.S.3
Aykin- Burns, N.4
Kim, H.S.5
Mishra, M.6
Sun, L.7
Nguyen, P.8
Ahn, B.H.9
Leclerc, J.10
Deng, C.X.11
Spitz, D.R.12
Gius, D.13
-
44
-
-
67649819237
-
Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes
-
Olmos Y, Valle I, Borniquel S, Tierrez A, Soria E, Lamas S, Monsalve M: Mutual dependence of Foxo3a and PGC-1alpha in the induction of oxidative stress genes. J Biol Chem 2009; 284: 14476-14484.
-
(2009)
J Biol Chem
, vol.284
, pp. 14476-14484
-
-
Olmos, Y.1
Valle, I.2
Borniquel, S.3
Tierrez, A.4
Soria, E.5
Lamas, S.6
Monsalve, M.7
-
45
-
-
80054746880
-
Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation
-
Lombard DB, Tishkoff DX, Bao J: Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation. Handb Exp Pharmacol 2011; 206: 163-188.
-
(2011)
Handb Exp Pharmacol
, vol.206
, pp. 163-188
-
-
Lombard, D.B.1
Tishkoff, D.X.2
Bao, J.3
-
46
-
-
77951705893
-
Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoforms
-
Bao J, Lu Z, Joseph JJ, Carabenciov D, Dimond CC, Pang L, Samsel L, McCoy JP Jr, Leclerc J, Nguyen P, Gius D, Sack MN: Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoforms. J Cell Biochem 2010; 110: 238-247.
-
(2010)
J Cell Biochem
, vol.110
, pp. 238-247
-
-
Bao, J.1
Lu, Z.2
Joseph, J.J.3
Carabenciov, D.4
Dimond, C.C.5
Pang, L.6
Samsel, L.7
Leclerc, J.8
Nguyen, P.9
Gius, D.10
Sack, M.N.11
-
47
-
-
63749099484
-
A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein
-
Cooper HM, Huang JY, Verdin E, Spelbrink JN: A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein. PLoS One 2009; 4:e4986.
-
(2009)
PLoS One
, vol.4
-
-
Cooper, H.M.1
Huang, J.Y.2
Verdin, E.3
Spelbrink, J.N.4
-
48
-
-
61449209922
-
Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
-
Jin L, Galonek H, Israelian K, Choy W, Morrison M, Xia Y, Wang X, Xu Y, Yang Y, Smith JJ, Hoffmann E, Carney DP, Perni RB, Jirousek MR, Bemis JE, Milne JC, Sinclair DA, Westphal CH: Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3. Protein Sci 2009; 18: 514-525.
-
(2009)
Protein Sci
, vol.18
, pp. 514-525
-
-
Jin, L.1
Galonek, H.2
Israelian, K.3
Choy, W.4
Morrison, M.5
Xia, Y.6
Wang, X.7
Xu, Y.8
Yang, Y.9
Smith, J.J.10
Hoffmann, E.11
Carney, D.P.12
Perni, R.B.13
Jirousek, M.R.14
Bemis, J.E.15
Milne, J.C.16
Sinclair, D.A.17
Westphal, C.H.18
-
49
-
-
78049299600
-
Characterization of murine SIRT3 transcript variants and corresponding protein products
-
Yang Y, Hubbard BP, Sinclair DA, Tong Q: Characterization of murine SIRT3 transcript variants and corresponding protein products. J Cell Biochem 2010; 111: 1051-1058.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1051-1058
-
-
Yang, Y.1
Hubbard, B.P.2
Sinclair, D.A.3
Tong, Q.4
-
50
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP: SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci USA 2002; 99: 13653-13658.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
51
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
Schwer B, North BJ, Frye RA, Ott M, Verdin E: The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol 2002; 158: 647- 657.
-
(2002)
J Cell Biol
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
52
-
-
77955287479
-
Sirt3 protects in vitrofertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest
-
Kawamura Y, Uchijima Y, Horike N, Tonami K, Nishiyama K, Amano T, Asano T, Kurihara Y, Kurihara H: Sirt3 protects in vitrofertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest. J Clin Invest 2010; 120: 2817-2828.
-
(2010)
J Clin Invest
, vol.120
, pp. 2817-2828
-
-
Kawamura, Y.1
Uchijima, Y.2
Horike, N.3
Tonami, K.4
Nishiyama, K.5
Amano, T.6
Asano, T.7
Kurihara, Y.8
Kurihara, H.9
-
53
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP: SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 2008; 28: 6384-6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
54
-
-
34247271282
-
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
-
Scher MB, Vaquero A, Reinberg D: SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev 2007; 21: 920- 928.
-
(2007)
Genes Dev
, vol.21
, pp. 920-928
-
-
Scher, M.B.1
Vaquero, A.2
Reinberg, D.3
-
55
-
-
84871852995
-
SIRT3 functions in the nucleus in the control of stress-related gene expression
-
Iwahara T, Bonasio R, Narendra V, Reinberg D: SIRT3 functions in the nucleus in the control of stress-related gene expression. Mol Cell Biol 2012; 32: 5022-5034.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 5022-5034
-
-
Iwahara, T.1
Bonasio, R.2
Narendra, V.3
Reinberg, D.4
-
56
-
-
37549026223
-
Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5
-
Nakamura Y, Ogura M, Tanaka D, Inagaki N: Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5. Biochem Biophys Res Commun 2008; 366: 174-179.
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 174-179
-
-
Nakamura, Y.1
Ogura, M.2
Tanaka, D.3
Inagaki, N.4
-
57
-
-
77954353059
-
Peroxisome proliferator- activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: Possible direct function in mitochondrial biogenesis
-
Aquilano K, Vigilanza P, Baldelli S, Pagliei B, Rotilio G, Ciriolo MR: Peroxisome proliferator- activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem 2010; 285: 21590-21599.
-
(2010)
J Biol Chem
, vol.285
, pp. 21590-21599
-
-
Aquilano, K.1
Vigilanza, P.2
Baldelli, S.3
Pagliei, B.4
Rotilio, G.5
Ciriolo, M.R.6
-
58
-
-
79953232671
-
Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial crosstalk to coordinate mitochondrial biogenesis
-
Safdar A, Little JP, Stokl AJ, Hettinga BP, Akhtar M, Tarnopolsky MA: Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial crosstalk to coordinate mitochondrial biogenesis. J Biol Chem 2011; 286: 10605-10617.
-
(2011)
J Biol Chem
, vol.286
, pp. 10605-10617
-
-
Safdar, A.1
Little, J.P.2
Stokl, A.J.3
Hettinga, B.P.4
Akhtar, M.5
Tarnopolsky, M.A.6
-
59
-
-
84878979986
-
A novel PGC-1alpha isoform in brain localizes to mitochondria and associates with PINK1 and VDAC
-
Choi J, Batchu VV, Schubert M, Castellani RJ, Russell JW: A novel PGC-1alpha isoform in brain localizes to mitochondria and associates with PINK1 and VDAC. Biochem Biophys Res Commun 2013; 435: 671-677.
-
(2013)
Biochem Biophys Res Commun
, vol.435
, pp. 671-677
-
-
Choi, J.1
Batchu, V.V.2
Schubert, M.3
Castellani, R.J.4
Russell, J.W.5
-
60
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC- 1{alpha}
-
Nemoto S, Fergusson MM, Finkel T: SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC- 1{alpha}. J Biol Chem 2005; 280: 16456-16460.
-
(2005)
J Biol Chem
, vol.280
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
61
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P: Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005; 434: 113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
62
-
-
84878305687
-
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels
-
Peserico A, Chiacchiera F, Grossi V, Matrone A, Latorre D, Simonatto M, Fusella A, Ryall JG, Finley LW, Haigis MC, Villani G, Puri PL, Sartorelli V, Simone C: A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels. Cell Mol Life Sci 2013; 70: 2015-2029.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 2015-2029
-
-
Peserico, A.1
Chiacchiera, F.2
Grossi, V.3
Matrone, A.4
Latorre, D.5
Simonatto, M.6
Fusella, A.7
Ryall, J.G.8
Finley, L.W.9
Haigis, M.C.10
Villani, G.11
Puri, P.L.12
Sartorelli, V.13
Simone, C.14
-
63
-
-
66049087696
-
The coordination of nuclear and mitochondrial communication during aging and calorie restriction
-
Finley LW, Haigis MC: The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev 2009; 8: 173-188.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 173-188
-
-
Finley, L.W.1
Haigis, M.C.2
-
64
-
-
84872276165
-
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome
-
Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ: Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Mol Cell 2013; 49: 186-199.
-
(2013)
Mol Cell
, vol.49
, pp. 186-199
-
-
Hebert, A.S.1
Dittenhafer-Reed, K.E.2
Yu, W.3
Bailey, D.J.4
Selen, E.S.5
Boersma, M.D.6
Carson, J.J.7
Tonelli, M.8
Balloon, A.J.9
Higbee, A.J.10
Westphall, M.S.11
Pagliarini, D.J.12
Prolla, T.A.13
Assadi-Porter, F.14
Roy, S.15
Denu, J.M.16
Coon, J.J.17
-
65
-
-
84855182851
-
Amp-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
-
Salminen A, Kaarniranta K: Amp-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev 2012; 11: 230-241.
-
(2012)
Ageing Res Rev
, vol.11
, pp. 230-241
-
-
Salminen, A.1
Kaarniranta, K.2
-
66
-
-
80051609656
-
Calorie restriction: Is AMPK a key sensor and effector?
-
Canto C, Auwerx J: Calorie restriction: is AMPK a key sensor and effector? Physiology (Bethesda) 2011; 26: 214-224.
-
(2011)
Physiology (Bethesda)
, vol.26
, pp. 214-224
-
-
Canto, C.1
Auwerx, J.2
-
67
-
-
63849301000
-
AMPK: Lessons from transgenic and knockout animals
-
(Landmark Ed)
-
Viollet B, Athea Y, Mounier R, Guigas B, Zarrinpashneh E, Horman S, Lantier L, Hebrard S, Devin-Leclerc J, Beauloye C, Foretz M, Andreelli F, Ventura-Clapier R, Bertrand L: AMPK: lessons from transgenic and knockout animals. Front Biosci (Landmark Ed) 2009; 14: 19-44.
-
(2009)
Front Biosci
, vol.14
, pp. 19-44
-
-
Viollet, B.1
Athea, Y.2
Mounier, R.3
Guigas, B.4
Zarrinpashneh, E.5
Horman, S.6
Lantier, L.7
Hebrard, S.8
Devin-Leclerc, J.9
Beauloye, C.10
Foretz, M.11
Andreelli, F.12
Ventura-Clapier, R.13
Bertrand, L.14
-
68
-
-
84861589885
-
Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis
-
Fernandez-Marcos PJ, Jeninga EH, Canto C, Harach T, de Boer VC, Andreux P, Moullan N, Pirinen E, Yamamoto H, Houten SM, Schoonjans K, Auwerx J: Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis. Sci Rep 2012; 2: 425.
-
(2012)
Sci Rep
, vol.2
, pp. 425
-
-
Fernandez-Marcos, P.J.1
Jeninga, E.H.2
Canto, C.3
Harach, T.4
De Boer, V.C.5
Andreux, P.6
Moullan, N.7
Pirinen, E.8
Yamamoto, H.9
Houten, S.M.10
Schoonjans, K.11
Auwerx, J.12
-
69
-
-
84871434149
-
Impact of maternal diabetes on epigenetic modifications leading to diseases in the offspring
-
Vrachnis N, Antonakopoulos N, Iliodromiti Z, Dafopoulos K, Siristatidis C, Pappa KI, Deligeoroglou E, Vitoratos N: Impact of maternal diabetes on epigenetic modifications leading to diseases in the offspring. Exp Diabetes Res 2012; 2012: 538474.
-
(2012)
Exp Diabetes Res
, vol.2012
, pp. 538474
-
-
Vrachnis, N.1
Antonakopoulos, N.2
Iliodromiti, Z.3
Dafopoulos, K.4
Siristatidis, C.5
Pappa, K.I.6
Deligeoroglou, E.7
Vitoratos, N.8
-
70
-
-
78650944949
-
The cell-non-autonomous nature of electron transport chainmediated longevity
-
Durieux J, Wolff S, Dillin A: The cell-non-autonomous nature of electron transport chainmediated longevity. Cell 2011; 144: 79-91.
-
(2011)
Cell
, vol.144
, pp. 79-91
-
-
Durieux, J.1
Wolff, S.2
Dillin, A.3
-
71
-
-
84870668412
-
Protection against ischemia-induced oxidative stress conferred by vagal stimulation in the rat heart: Involvement of the AMPK-PKC pathway
-
Kong SS, Liu JJ, Yu XJ, Lu Y, Zang WJ: Protection against ischemia-induced oxidative stress conferred by vagal stimulation in the rat heart: involvement of the AMPK-PKC pathway. Int J Mol Sci 2012; 13: 14311-14325.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 14311-14325
-
-
Kong, S.S.1
Liu, J.J.2
Yu, X.J.3
Lu, Y.4
Zang, W.J.5
-
72
-
-
84872057896
-
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
-
Kim KH, Jeong YT, Oh H, Kim SH, Cho JM, Kim YN, Kim SS, Kim do H, Hur KY, Kim HK, Ko T, Han J, Kim HL, Kim J, Back SH, Komatsu M, Chen H, Chan DC, Konishi M, Itoh N, Choi CS, Lee MS: Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med 2013; 19: 83-92.
-
(2013)
Nat Med
, vol.19
, pp. 83-92
-
-
Kim, K.H.1
Jeong, Y.T.2
Oh, H.3
Kim, S.H.4
Cho, J.M.5
Kim, Y.N.6
Kim, S.S.7
Kim Do, H.8
Hur, K.Y.9
Kim, H.K.10
Ko, T.11
Han, J.12
Kim, H.L.13
Kim, J.14
Back, S.H.15
Komatsu, M.16
Chen, H.17
Chan, D.C.18
Konishi, M.19
Itoh, N.20
Choi, C.S.21
Lee, M.S.22
more..
|