A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels

Cellular and Molecular Life Sciences

Volumn 70, Issue 11, 2013, Pages 2015-2029

  Peserico, Alessia ^a   Chiacchiera, Fulvio ^a   Grossi, Valentina ^b   Matrone, Antonio ^a   Latorre, Dominga ^c   Simonatto, Marta ^d   Fusella, Aurora ^e   Ryall, James G ^f   Finley, Lydia W S ^g   Haigis, Marcia C ^g   Villani, Gaetano ^c   Puri, Pier Lorenzo ^d   Sartorelli, Vittorio ^f   Simone, Cristiano ^a,c  

^a Laboratory of Signal dependent Transcription   (Italy)

^b NATIONAL INSTITUTE FOR DIGESTIVE DISEASES   (Italy)

^c UNIVERSITY OF BARI   (Italy)

^d IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^e NIH ^*  (Italy)

^f NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

Author keywords

AMPK; FoxO3A; Glucose restriction; OXPHOS; SIRT3

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOCHONDRIAL DNA; MITOCHONDRIAL RNA POLYMERASE; RNA POLYMERASE; SIRTUIN 3; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL METABOLISM; COMPLEX FORMATION; CONTROLLED STUDY; DIET RESTRICTION; EMBRYO; ENERGY METABOLISM; FIBROBLAST; GENE EXPRESSION REGULATION; MALE; MITOCHONDRIAL GENOME; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; MYOTUBE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; SKELETAL MUSCLE;

ADENYLATE KINASE; ANIMALS; CELLS, CULTURED; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; ENERGY METABOLISM; FOOD DEPRIVATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENOME, MITOCHONDRIAL; GLUCOSE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MODELS, BIOLOGICAL; NIH 3T3 CELLS; SIRTUIN 3;

MAMMALIA; MUS;

EID: 84878305687     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1244-6     Document Type: Article

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