Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in th1th17 cells and identifies peroxisome proliferator-activated receptor gamma as an intrinsic negative regulator of viral replication

Retrovirology

Volumn 10, Issue 1, 2013, Pages

  Bernier, Annie ^a,b   Cleret Buhot, Aurélie ^a,b   Zhang, Yuwei ^a,b   Goulet, Jean Philippe ^a   Monteiro, Patricia ^a,b   Gosselin, Annie ^b   DaFonseca, Sandrina ^a,b   Wacleche, Vanessa S ^a,b   Jenabian, Mohammad Ali ^c   Routy, Jean Pierre ^c   Tremblay, Cécile ^a,b   Ancuta, Petronela ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

CD4+ T cells; cDNA microarrays; HIV; PPAR ; Th1; Th1Th17

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; ALPHA INTERFERON; BETA INTERFERON; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CD146 ANTIGEN; CD28 ANTIGEN; CD40 LIGAND; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR6; FOCAL ADHESION KINASE 1; FURIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 26; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 13; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P53; RETINOID RELATED ORPHAN RECEPTOR GAMMA; ROSIGLITAZONE; SERINE PROTEINASE INHIBITOR; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR RUNX1;

ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE ONTOLOGY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; INFLAMMATION; MICROARRAY ANALYSIS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TRANSCRIPTION REGULATION; UPREGULATION; VIRUS DNA CELL DNA INTERACTION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSCRIPTION;

HUMAN IMMUNODEFICIENCY VIRUS 1; VESICULAR STOMATITIS VIRUS;

CELLS, CULTURED; ECHOCARDIOGRAPHY, DOPPLER, COLOR; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; PPAR GAMMA; REAL-TIME POLYMERASE CHAIN REACTION; TH1 CELLS; TH17 CELLS; VIRUS REPLICATION;

EID: 84890538169     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-160     Document Type: Article

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