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Volumn 70, Issue 16, 2010, Pages 6516-6526

KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 6; HELIX LOOP HELIX PROTEIN; HETEROCHROMATIN PROTEIN 1; HIGH MOBILITY GROUP A2 PROTEIN; I KAPPA B KINASE EPSILON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KRUPPEL LIKE FACTOR; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MYC PROTEIN; STAT3 PROTEIN; STAT5B PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR ZNF382; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; DNA BINDING PROTEIN; I KAPPA B KINASE; ID1 PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; INHIBITOR OF DIFFERENTIATION 1; STAT3 PROTEIN, HUMAN; STAT5 PROTEIN; STAT5B PROTEIN, HUMAN; TRANSCRIPTION FACTOR; ZNF382 PROTEIN, HUMAN;

EID: 77955728660     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4566     Document Type: Article
Times cited : (115)

References (50)
  • 1
    • 33644843641 scopus 로고    scopus 로고
    • Molecular mechanisms of human carcinogenesis
    • Coleman WB, Tsongalis GJ. Molecular mechanisms of human carcinogenesis. EXS 2006;96:321-49.
    • (2006) EXS , vol.96 , pp. 321-349
    • Coleman, W.B.1    Tsongalis, G.J.2
  • 2
    • 33750821725 scopus 로고    scopus 로고
    • Tumor suppressor gene methylation in follicular lymphoma: A comprehensive review
    • DOI 10.1186/1476-4598-5-44
    • Hayslip J, Montero A. Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review. Mol Cancer 2006;5:44. (Pubitemid 44712390)
    • (2006) Molecular Cancer , vol.5 , pp. 44
    • Hayslip, J.1    Montero, A.2
  • 3
    • 0032731581 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes in cancer
    • Herman JG. Hypermethylation of tumor suppressor genes in cancer. Semin Cancer Biol 1999;9:359-67.
    • (1999) Semin Cancer Biol , vol.9 , pp. 359-367
    • Herman, J.G.1
  • 4
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002;3:415-28.
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 5
    • 34249029692 scopus 로고    scopus 로고
    • Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: Identification of a ZNF217 consensus recognition sequence
    • DOI 10.1038/sj.onc.1210126, PII 1210126
    • Cowger JJ, Zhao Q, Isovic M, Torchia J. Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence. Oncogene 2007;26:3378-86. (Pubitemid 46788885)
    • (2007) Oncogene , vol.26 , Issue.23 , pp. 3378-3386
    • Cowger, J.J.M.1    Zhao, Q.2    Isovic, M.3    Torchia, J.4
  • 6
    • 33845505242 scopus 로고    scopus 로고
    • 1 cell-cycle arrest and apoptosis by positively regulating p53 transcriptional activity
    • DOI 10.1182/blood-2006-06-029645
    • Yang M, Wu S, Su X, May WS. JAZ mediates G1 cell-cycle arrest and apoptosis by positively regulating p53 transcriptional activity. Blood 2006;108:4136-45. (Pubitemid 44913285)
    • (2006) Blood , vol.108 , Issue.13 , pp. 4136-4145
    • Yang, M.1    Wu, S.2    Su, X.3    May, W.S.4
  • 7
    • 0346274978 scopus 로고    scopus 로고
    • KRAB-containing zinc-finger repressor proteins
    • Urrutia R. KRAB-containing zinc-finger repressor proteins. Genome Biol 2003;4:231.
    • (2003) Genome Biol , vol.4 , pp. 231
    • Urrutia, R.1
  • 8
    • 67349221185 scopus 로고    scopus 로고
    • KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis
    • Tian C, Xing G, Xie P, et al. KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis. Nat Cell Biol 2009;11:580-91.
    • (2009) Nat Cell Biol , vol.11 , pp. 580-591
    • Tian, C.1    Xing, G.2    Xie, P.3
  • 9
    • 33845974401 scopus 로고    scopus 로고
    • Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression
    • DOI 10.1016/j.yexcr.2006.10.009, PII S0014482706004277
    • Huang C, Jia Y, Yang S, et al. Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression. Exp Cell Res 2007;313:254-63. (Pubitemid 46048814)
    • (2007) Experimental Cell Research , vol.313 , Issue.2 , pp. 254-263
    • Huang, C.1    Jia, Y.2    Yang, S.3    Chen, B.4    Sun, H.5    Shen, F.6    Wang, Y.7
  • 10
    • 1342304121 scopus 로고    scopus 로고
    • Functional Dissection of Transcription Factor ZBRK1 Reveals Zinc Fingers with Dual Roles in DNA-binding and BRCA1-dependent Transcriptional Repression
    • DOI 10.1074/jbc.M312270200
    • Tan W, Zheng L, Lee WH, Boyer TG. Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression. J Biol Chem 2004;279:6576-87. (Pubitemid 38248794)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.8 , pp. 6576-6587
    • Tan, W.1    Zheng, L.2    Lee, W.-H.3    Boyer, T.G.4
  • 12
    • 0345390860 scopus 로고    scopus 로고
    • Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the Black and Colored populations of South Africa
    • Du PL, Dietzsch E, Van GM, et al. Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the Black and Colored populations of South Africa. Cancer Res 1999;59:1877-83.
    • (1999) Cancer Res , vol.59 , pp. 1877-1883
    • Du, P.L.1    Dietzsch, E.2    Van, G.M.3
  • 13
    • 0035162463 scopus 로고    scopus 로고
    • Loss of heterozygosity and its correlation with clinical outcome and Epstein-Barr virus infection in nasopharyngeal carcinoma
    • Shao JY, Huang XM, Yu XJ, et al. Loss of heterozygosity and its correlation with clinical outcome and Epstein-Barr virus infection in nasopharyngeal carcinoma. Anticancer Res 2001;21:3021-9.
    • (2001) Anticancer Res , vol.21 , pp. 3021-3029
    • Shao, J.Y.1    Huang, X.M.2    Yu, X.J.3
  • 14
    • 0036921617 scopus 로고    scopus 로고
    • Expression of a novel Krupple-like zinc-finger gene, ZNF382, in human heart
    • Luo K, Yuan W, Zhu C, et al. Expression of a novel Krupple-like zinc-finger gene, ZNF382, in human heart. Biochem Biophys Res Commun 2002;299:606-12.
    • (2002) Biochem Biophys Res Commun , vol.299 , pp. 606-612
    • Luo, K.1    Yuan, W.2    Zhu, C.3
  • 15
    • 52049115449 scopus 로고    scopus 로고
    • OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation
    • Cui Y, Ying Y, van HA, et al. OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation. PLoS ONE 2008;3:e2990.
    • (2008) PLoS ONE , vol.3
    • Cui, Y.1    Ying, Y.2    Van, H.A.3
  • 16
    • 33244483580 scopus 로고    scopus 로고
    • Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation
    • DOI 10.1038/sj.onc.1209154, PII 1209154
    • Ying J, Li H, Seng TJ, et al. Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene 2006;25:1070-80. (Pubitemid 43277014)
    • (2006) Oncogene , vol.25 , Issue.7 , pp. 1070-1080
    • Ying, J.1    Li, H.2    Seng, T.J.3    Langford, C.4    Srivastava, G.5    Tsao, S.W.6    Putti, T.7    Murray, P.8    Chan, A.T.C.9    Tao, Q.10
  • 17
    • 0037531524 scopus 로고    scopus 로고
    • Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma
    • Liu XQ, Chen HK, Zhang XS, et al. Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma. Int J Cancer 2003;106:60-5.
    • (2003) Int J Cancer , vol.106 , pp. 60-65
    • Liu, X.Q.1    Chen, H.K.2    Zhang, X.S.3
  • 18
    • 67449127092 scopus 로고    scopus 로고
    • CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis
    • Wang Y, Li J, Cui Y, et al. CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis. Cancer Res 2009;69:5194-201.
    • (2009) Cancer Res , vol.69 , pp. 5194-5201
    • Wang, Y.1    Li, J.2    Cui, Y.3
  • 20
    • 2942737278 scopus 로고    scopus 로고
    • The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma
    • Qiu GH, Tan LK, Loh KS, et al. The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma. Oncogene 2004;23:4793-806.
    • (2004) Oncogene , vol.23 , pp. 4793-4806
    • Qiu, G.H.1    Tan, L.K.2    Loh, K.S.3
  • 22
    • 40749119357 scopus 로고    scopus 로고
    • WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/β-catenin signaling, and is frequently methylated in colorectal cancer
    • DOI 10.1158/1078-0432.CCR-07-1644
    • Ying J, Li H, Yu J, et al. WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/β-catenin signaling, and is frequently methylated in colorectal cancer. Clin Cancer Res 2008;14:55-61. (Pubitemid 351377978)
    • (2008) Clinical Cancer Research , vol.14 , Issue.1 , pp. 55-61
    • Ying, J.1    Li, H.2    Yu, J.3    Ka, M.N.4    Fan, F.P.5    Wong, S.C.C.6    Chan, A.T.C.7    Sung, J.J.Y.8    Tao, Q.9
  • 23
    • 0032423820 scopus 로고    scopus 로고
    • KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1
    • Gebelein B, Fernandez-Zapico M, Imoto M, Urrutia R. KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1. J Clin Invest 1998;102:1911-9.
    • (1998) J Clin Invest , vol.102 , pp. 1911-1919
    • Gebelein, B.1    Fernandez-Zapico, M.2    Imoto, M.3    Urrutia, R.4
  • 24
    • 0035136902 scopus 로고    scopus 로고
    • Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Kruppel-associated box protein
    • DOI 10.1128/MCB.21.3.928-939.2001
    • Gebelein B, Urrutia R. Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Kruppel-associated box protein. Mol Cell Biol 2001;21:928-39. (Pubitemid 32104740)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.3 , pp. 928-939
    • Gebelein, B.1    Urrutia, R.2
  • 25
    • 33750432183 scopus 로고    scopus 로고
    • Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression
    • Basseres DS, Baldwin AS. Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression. Oncogene 2006;25:6817-30.
    • (2006) Oncogene , vol.25 , pp. 6817-6830
    • Basseres, D.S.1    Baldwin, A.S.2
  • 26
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-edged sword in tumorigenesis
    • Eferl R, Wagner EF. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer 2003;3:859-68.
    • (2003) Nat Rev Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 27
    • 63249092765 scopus 로고    scopus 로고
    • Persistently activated Stat3 maintains constitutive NF-κB activity in tumors
    • Lee H, Herrmann A, Deng JH, et al. Persistently activated Stat3 maintains constitutive NF-κB activity in tumors. Cancer Cell 2009;15:283-93.
    • (2009) Cancer Cell , vol.15 , pp. 283-293
    • Lee, H.1    Herrmann, A.2    Deng, J.H.3
  • 28
    • 58249085437 scopus 로고    scopus 로고
    • Regulation of intestinal barrier function by signal transducer and activator of transcription 5b
    • Han X, Ren X, Jurickova I, et al. Regulation of intestinal barrier function by signal transducer and activator of transcription 5b. Gut 2009;58:49-58.
    • (2009) Gut , vol.58 , pp. 49-58
    • Han, X.1    Ren, X.2    Jurickova, I.3
  • 30
    • 0043170868 scopus 로고    scopus 로고
    • Id-1 expression promotes cell survival through activation of NF-κB signalling pathway in prostate cancer cells
    • DOI 10.1038/sj.onc.1206693
    • Ling MT, Wang X, Ouyang XS, Xu K, Tsao SW, Wong YC. Id-1 expression promotes cell survival through activation of NF-κB signalling pathway in prostate cancer cells. Oncogene 2003;22:4498-508. (Pubitemid 36920693)
    • (2003) Oncogene , vol.22 , Issue.29 , pp. 4498-4508
    • Ling, M.-T.1    Wang, X.2    Ouyang, X.-S.3    Xu, K.4    Tsao, S.-W.5    Wong, Y.-C.6
  • 31
    • 0033013868 scopus 로고    scopus 로고
    • KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: A potential role for Kruppel-associated box- Zinc finger proteins in heterochromatin-mediated gene silencing
    • Ryan RF, Schultz DC, Ayyanathan K, et al. KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. Mol Cell Biol 1999;19:4366-78. (Pubitemid 29242011)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.6 , pp. 4366-4378
    • Ryan, R.F.1    Schultz, D.C.2    Ayyanathan, K.3    Singh, P.B.4    Friedman, J.R.5    Fredericks, W.J.6    Rauscher III, F.J.7
  • 32
    • 73749088654 scopus 로고    scopus 로고
    • Epigenetic opportunities and challenges in cancer
    • Best JD, Carey N. Epigenetic opportunities and challenges in cancer. Drug Discov Today 2010;15:65-70.
    • (2010) Drug Discov Today , vol.15 , pp. 65-70
    • Best, J.D.1    Carey, N.2
  • 34
    • 53249098795 scopus 로고    scopus 로고
    • A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints
    • Li X, Ito M, Zhou F, et al. A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev Cell 2008;15:547-57.
    • (2008) Dev Cell , vol.15 , pp. 547-557
    • Li, X.1    Ito, M.2    Zhou, F.3
  • 35
    • 0037089626 scopus 로고    scopus 로고
    • SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
    • DOI 10.1101/gad.973302
    • Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ III. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev 2002;16:919-32. (Pubitemid 34408542)
    • (2002) Genes and Development , vol.16 , Issue.8 , pp. 919-932
    • Schultz, D.C.1    Ayyanathan, K.2    Negorev, D.3    Maul, G.G.4    Rauscher III, F.J.5
  • 36
    • 77955726591 scopus 로고    scopus 로고
    • Tumorigenesis is a disease of heterochromatin assembly and disruption of the epigenetic mark
    • Wong David K., editor. Nova Science publishers
    • Wynter Coral, Alfonzo Marcelo, Lippo de Becemberg Itala. Tumorigenesis is a disease of heterochromatin assembly and disruption of the epigenetic mark. In: Wong David K., editor. Tumorigenesis Research Advances. Nova Science publishers; 2007, p. 201-226.
    • (2007) Tumorigenesis Research Advances , pp. 201-226
    • Coral, W.1    Marcelo, A.2    De Becemberg Itala, L.3
  • 37
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008;8:976-90.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 38
    • 44849094211 scopus 로고    scopus 로고
    • Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas
    • Dynek JN, Chan SM, Liu J, Zha J, Fairbrother WJ, Vucic D. Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas. Cancer Res 2008;68:3124-32.
    • (2008) Cancer Res , vol.68 , pp. 3124-3132
    • Dynek, J.N.1    Chan, S.M.2    Liu, J.3    Zha, J.4    Fairbrother, W.J.5    Vucic, D.6
  • 39
    • 0037071390 scopus 로고    scopus 로고
    • Cell cycle regulators and hematopoiesis
    • Steinman RA. Cell cycle regulators and hematopoiesis. Oncogene 2002;21:3403-13.
    • (2002) Oncogene , vol.21 , pp. 3403-3413
    • Steinman, R.A.1
  • 40
    • 1242318505 scopus 로고    scopus 로고
    • STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression
    • DOI 10.1038/sj.onc.1207174
    • Joo A, Aburatani H, Morii E, Iba H, Yoshimura A. STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression. Oncogene 2004;23:726-34. (Pubitemid 38241273)
    • (2004) Oncogene , vol.23 , Issue.3 , pp. 726-734
    • Joo, A.1    Aburatani, H.2    Morii, E.3    Iba, H.4    Yoshimura, A.5
  • 41
    • 85047699472 scopus 로고    scopus 로고
    • Thyroid cell transformation requires the expression of the HMGA1 proteins
    • DOI 10.1038/sj/onc/1205368
    • Berlingieri MT, Pierantoni GM, Giancotti V, Santoro M, Fusco A. Thyroid cell transformation requires the expression of the HMGA1 proteins. Oncogene 2002;21:2971-80. (Pubitemid 34522896)
    • (2002) Oncogene , vol.21 , Issue.19 , pp. 2971-2980
    • Berlingieri, M.T.1    Pierantoni, G.M.2    Giancotti, V.3    Santoro, M.4    Fusco, A.5
  • 42
    • 51049103668 scopus 로고    scopus 로고
    • HMGA2 participates in transformation in human lung cancer
    • Di CF, Hillion J, Hristov A, et al. HMGA2 participates in transformation in human lung cancer. Mol Cancer Res 2008;6:743-50.
    • (2008) Mol Cancer Res , vol.6 , pp. 743-750
    • Di, C.F.1    Hillion, J.2    Hristov, A.3
  • 43
    • 53949096318 scopus 로고    scopus 로고
    • Id-1 regulates Bcl-2 and Bax expression through p53 and NF-κB in MCF-7 breast cancer cells
    • Kim H, Chung H, Kim HJ, et al. Id-1 regulates Bcl-2 and Bax expression through p53 and NF-κB in MCF-7 breast cancer cells. Breast Cancer Res Treat 2008;112:287-96.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 287-296
    • Kim, H.1    Chung, H.2    Kim, H.J.3
  • 45
    • 68049148471 scopus 로고    scopus 로고
    • CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-κB
    • Kashima L, Toyota M, Mita H, et al. CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-κB. Oncogene 2009;28:2643-53.
    • (2009) Oncogene , vol.28 , pp. 2643-2653
    • Kashima, L.1    Toyota, M.2    Mita, H.3
  • 47
    • 40449141403 scopus 로고    scopus 로고
    • Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both κ-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells
    • DOI 10.1038/sj.onc.1210793, PII 1210793
    • Wang Q, Sun Z, Yang HS. Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both κ-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells. Oncogene 2008;27:1527-35. (Pubitemid 351347877)
    • (2008) Oncogene , vol.27 , Issue.11 , pp. 1527-1535
    • Wang, Q.1    Sun, Z.2    Yang, H.-S.3
  • 48
    • 34250308298 scopus 로고    scopus 로고
    • Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells
    • DOI 10.1158/0008-5472.CAN-06-4645
    • Wang L, Zhang Y, Li H, Xu Z, Santella RM, Weinstein IB. Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells. Cancer Res 2007;67:4700-8. (Pubitemid 46910176)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4700-4708
    • Wang, L.1    Zhang, Y.2    Li, H.3    Xu, Z.4    Santella, R.M.5    Weinstein, I.B.6
  • 49
    • 33847312302 scopus 로고    scopus 로고
    • Gα12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IκBα
    • Ki SH, Choi MJ, Lee CH, Kim SG. Gα12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IκBα. J Biol Chem 2007;282:1938-47.
    • (2007) J Biol Chem , vol.282 , pp. 1938-1947
    • Ki, S.H.1    Choi, M.J.2    Lee, C.H.3    Kim, S.G.4
  • 50
    • 0037205429 scopus 로고    scopus 로고
    • Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins
    • Parnell SC, Magenheimer BS, Maser RL, Zien CA, Frischauf AM, Calvet JP. Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins. J Biol Chem 2002;277:19566-72.
    • (2002) J Biol Chem , vol.277 , pp. 19566-19572
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3    Zien, C.A.4    Frischauf, A.M.5    Calvet, J.P.6


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