메뉴 건너뛰기




Volumn 22, Issue 13, 2008, Pages 1539-1549

Peroxisome proliferator-activated receptor-γ activation suppresses HIV-1 replication in an animal model of encephalitis

Author keywords

Animal model of HIV 1 encephalitis; Brain macrophages; Peroxisome proliferator activated receptor ; Rosiglitazone; Suppression of HIV 1 replication

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PLACEBO; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; SMALL INTERFERING RNA;

EID: 52249105801     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3283081e08     Document Type: Article
Times cited : (39)

References (57)
  • 1
    • 0347320928 scopus 로고    scopus 로고
    • Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection
    • Persidsky Y, Gendelman HE. Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection. J Leukoc Biol 2003; 74:691-701.
    • (2003) J Leukoc Biol , vol.74 , pp. 691-701
    • Persidsky, Y.1    Gendelman, H.E.2
  • 2
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome prolifera-tor-activated receptor agonists
    • Staels B, FruchartJC. Therapeutic roles of peroxisome prolifera-tor-activated receptor agonists. Diabetes 2005; 54:2460-2470.
    • (2005) Diabetes , vol.54 , pp. 2460-2470
    • Staels, B.1    FruchartJC2
  • 3
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 4
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 5
    • 30944457985 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Potential therapeutic targets in lung disease?
    • Denning GM, Stoll LL. Peroxisome proliferator-activated receptors: potential therapeutic targets in lung disease? Pediatr Pulmonol 2006; 41:23-34.
    • (2006) Pediatr Pulmonol , vol.41 , pp. 23-34
    • Denning, G.M.1    Stoll, L.L.2
  • 6
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, et al. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A 1998; 95:7614-7619.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3    Li, A.4    Welch, J.5    Najib, J.6
  • 7
    • 26844468856 scopus 로고    scopus 로고
    • Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients
    • Klotz L, Schmidt M, Giese T, Sastre M, Knolle P, Klockgether T, Heneka MT. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. J Immunol 2005; 175:4948-4955.
    • (2005) J Immunol , vol.175 , pp. 4948-4955
    • Klotz, L.1    Schmidt, M.2    Giese, T.3    Sastre, M.4    Knolle, P.5    Klockgether, T.6    Heneka, M.T.7
  • 8
    • 11844269951 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis
    • Kiaei M, Kipiani K, Chen J, Calingasan NY, Beal MF. Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis. Exp Neurol 2005; 191:331-336.
    • (2005) Exp Neurol , vol.191 , pp. 331-336
    • Kiaei, M.1    Kipiani, K.2    Chen, J.3    Calingasan, N.Y.4    Beal, M.F.5
  • 9
    • 27944434620 scopus 로고    scopus 로고
    • Therapeutic targets in inflammatory disease
    • Hume DA, Fairlie DP. Therapeutic targets in inflammatory disease. Curr Med Chem 2005; 12:2925-2929.
    • (2005) Curr Med Chem , vol.12 , pp. 2925-2929
    • Hume, D.A.1    Fairlie, D.P.2
  • 10
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation
    • Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J Neurochem 2004; 88:494-501.
    • (2004) J Neurochem , vol.88 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 11
    • 0035341427 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalo-myelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma
    • Niino M, Iwabuchi K, Kikuchi S, Ato M, Morohashi T, Ogata A, et al. Amelioration of experimental autoimmune encephalo-myelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma. J Neuroimmunol 2001; 116:40-48.
    • (2001) J Neuroimmunol , vol.116 , pp. 40-48
    • Niino, M.1    Iwabuchi, K.2    Kikuchi, S.3    Ato, M.4    Morohashi, T.5    Ogata, A.6
  • 12
    • 0037311051 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation
    • Kiel ian T, Drew PD. Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation. J Neurosci Res 2003; 71:315-325.
    • (2003) J Neurosci Res , vol.71 , pp. 315-325
    • Kiel ian, T.1    Drew, P.D.2
  • 13
    • 10044225937 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide
    • Camacho IE, Serneels L, Spittaels K, Merchiers P, Dominguez D, De Strooper B. Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide. J Neurosci 2004; 24:10908-10917.
    • (2004) J Neurosci , vol.24 , pp. 10908-10917
    • Camacho, I.E.1    Serneels, L.2    Spittaels, K.3    Merchiers, P.4    Dominguez, D.5    De Strooper, B.6
  • 14
    • 33644516288 scopus 로고    scopus 로고
    • Contribution of inflammatory processes to Alzheimer's disease: Molecular mechanisms
    • Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci 2006; 24:167-176.
    • (2006) Int J Dev Neurosci , vol.24 , pp. 167-176
    • Sastre, M.1    Klockgether, T.2    Heneka, M.T.3
  • 15
    • 0037053290 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists inhibit HIV-1 replication in macrophages by transcriptional and post-transcriptional effects
    • Hayes MM, Lane BR, King SR, Markovitz DM, Coffey MJ. Peroxisome proliferator-activated receptor gamma agonists inhibit HIV-1 replication in macrophages by transcriptional and post-transcriptional effects. J Biol Chem 2002; 277:16913-16919.
    • (2002) J Biol Chem , vol.277 , pp. 16913-16919
    • Hayes, M.M.1    Lane, B.R.2    King, S.R.3    Markovitz, D.M.4    Coffey, M.J.5
  • 16
    • 0036738829 scopus 로고    scopus 로고
    • Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects
    • Skolnik PR, Rabbi MF, MathysJM, GreenbergAS. Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. J Acquir Immune Defic Syndr 2002; 31:1-10.
    • (2002) J Acquir Immune Defic Syndr , vol.31 , pp. 1-10
    • Skolnik, P.R.1    Rabbi, M.F.2    MathysJM3    GreenbergAS4
  • 17
    • 27144489077 scopus 로고    scopus 로고
    • Inhibition of Indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in animal model of HIV-1 encephalitis
    • Potula R, Poluektova L, Knipe B, Chrastil J, Heilman D, Dou H, et al. Inhibition of Indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in animal model of HIV-1 encephalitis. Blood 2005; 106:2383-2390.
    • (2005) Blood , vol.106 , pp. 2383-2390
    • Potula, R.1    Poluektova, L.2    Knipe, B.3    Chrastil, J.4    Heilman, D.5    Dou, H.6
  • 18
    • 33645453995 scopus 로고    scopus 로고
    • Alcohol abuse enhances neuroinflammation and impairs immune responses in an animal model of human immunodeficiency virus-1 encephalitis
    • Potula R, Haorah J, Knipe B, Leibhart J, Chrastil J, Heilman D, et al. Alcohol abuse enhances neuroinflammation and impairs immune responses in an animal model of human immunodeficiency virus-1 encephalitis. Am J Pathol 2006; 168:1335-1344.
    • (2006) Am J Pathol , vol.168 , pp. 1335-1344
    • Potula, R.1    Haorah, J.2    Knipe, B.3    Leibhart, J.4    Chrastil, J.5    Heilman, D.6
  • 19
    • 0023898273 scopus 로고
    • Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1 -treated monocytes
    • Gendelman HE, Orenstein JM, Martin MA, Ferrua C, Mitra R, Phipps T, et al. Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1 -treated monocytes. J Exp Med 1988; 167:1428-1441.
    • (1988) J Exp Med , vol.167 , pp. 1428-1441
    • Gendelman, H.E.1    Orenstein, J.M.2    Martin, M.A.3    Ferrua, C.4    Mitra, R.5    Phipps, T.6
  • 20
    • 40749103882 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor {gamma} (PPAR{gamma}) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes
    • Ramirez SH, Heilman D, Morsey B, Potula R, Haorah J, Persidsky Y. Activation of peroxisome proliferator-activated receptor {gamma} (PPAR{gamma}) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes. J Immunol 2008; 180:1854-1865.
    • (2008) J Immunol , vol.180 , pp. 1854-1865
    • Ramirez, S.H.1    Heilman, D.2    Morsey, B.3    Potula, R.4    Haorah, J.5    Persidsky, Y.6
  • 21
    • 0035985758 scopus 로고    scopus 로고
    • Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and inflammatory responses of macrophages
    • Klappacher GW, Glass CK. Roles of peroxisome proliferator-activated receptor gamma in lipid homeostasis and inflammatory responses of macrophages. Curr Opin Lipidol 2002; 13:305-312.
    • (2002) Curr Opin Lipidol , vol.13 , pp. 305-312
    • Klappacher, G.W.1    Glass, C.K.2
  • 22
    • 0035851187 scopus 로고    scopus 로고
    • PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen ED, Spiegelman BM. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 2001; 276:37731-37734.
    • (2001) J Biol Chem , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 23
    • 33746080426 scopus 로고    scopus 로고
    • Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics
    • Lemay DG, Hwang DH. Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics. J Lipid Res 2006; 47:1583-1587.
    • (2006) J Lipid Res , vol.47 , pp. 1583-1587
    • Lemay, D.G.1    Hwang, D.H.2
  • 24
    • 0037161026 scopus 로고    scopus 로고
    • Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance
    • Bastard JP, Caron M, Vidal H, Jan V, Auclair M, Vigouroux C, et al. Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance. Lancet 2002; 359:1026-1031.
    • (2002) Lancet , vol.359 , pp. 1026-1031
    • Bastard, J.P.1    Caron, M.2    Vidal, H.3    Jan, V.4    Auclair, M.5    Vigouroux, C.6
  • 25
    • 0347951395 scopus 로고    scopus 로고
    • Regulation of HIV-1 gene transcription: From lymphocytes to microglial cells
    • Rohr O, Marban C, Aunis D, Schaeffer E. Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells. J Leukoc Biol 2003; 74:736-749.
    • (2003) J Leukoc Biol , vol.74 , pp. 736-749
    • Rohr, O.1    Marban, C.2    Aunis, D.3    Schaeffer, E.4
  • 26
    • 4344634285 scopus 로고    scopus 로고
    • HIV-1 gene expression: Lessons from provirus and nonintegrated DNA
    • Wu Y. HIV-1 gene expression: lessons from provirus and nonintegrated DNA. Retrovirology 2004; 1:13.
    • (2004) Retrovirology , vol.1 , pp. 13
    • Wu, Y.1
  • 27
    • 0034142332 scopus 로고    scopus 로고
    • A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter
    • Pereira LA, Bentley K, Peeters A, Churchill MJ, Deacon NJ. A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter. Nucleic Acids Res 2000; 28:663-668.
    • (2000) Nucleic Acids Res , vol.28 , pp. 663-668
    • Pereira, L.A.1    Bentley, K.2    Peeters, A.3    Churchill, M.J.4    Deacon, N.J.5
  • 28
    • 0035896735 scopus 로고    scopus 로고
    • Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: Implications for the neuro-pathogenesis of AIDS
    • Williams KC, Corey S, Westmoreland SV, Pauley D, Knight H, deBakker C, et al. Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuro-pathogenesis of AIDS. J Exp Med 2001; 193:905-915.
    • (2001) J Exp Med , vol.193 , pp. 905-915
    • Williams, K.C.1    Corey, S.2    Westmoreland, S.V.3    Pauley, D.4    Knight, H.5    deBakker, C.6
  • 30
    • 20444440328 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB signaling by fenofibrate, a peroxisome proliferator-activated receptor-alpha ligand, presents a therapeutic strategy for rheumatoid arthritis
    • Okamoto H, Iwamoto T, Kotake S, Momohara S, Yamanaka H, Kamatani N. Inhibition of NF-kappaB signaling by fenofibrate, a peroxisome proliferator-activated receptor-alpha ligand, presents a therapeutic strategy for rheumatoid arthritis. Clin Exp Rheumatol 2005; 23:323-330.
    • (2005) Clin Exp Rheumatol , vol.23 , pp. 323-330
    • Okamoto, H.1    Iwamoto, T.2    Kotake, S.3    Momohara, S.4    Yamanaka, H.5    Kamatani, N.6
  • 31
    • 33644822499 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligand prevents the development of chronic pancreatitis through modulating NF-kappaB-dependent proinflammatory cytokine production and pancreatic stel late cel l activation
    • Hisada S, Shimizu K, Shiratori K, Kobayashi M. Peroxisome proliferator-activated receptor gamma ligand prevents the development of chronic pancreatitis through modulating NF-kappaB-dependent proinflammatory cytokine production and pancreatic stel late cel l activation. Rocz Akad Med Bialymst 2005; 50:142-147.
    • (2005) Rocz Akad Med Bialymst , vol.50 , pp. 142-147
    • Hisada, S.1    Shimizu, K.2    Shiratori, K.3    Kobayashi, M.4
  • 32
    • 11144236524 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma and retinoid X receptor inhibits aromatase transcription via nuclear factor-kappaB
    • Fan W, Yanase T, Morinaga H, Mu YM, Nomura M, Okabe T, et al. Activation of peroxisome proliferator-activated receptor-gamma and retinoid X receptor inhibits aromatase transcription via nuclear factor-kappaB. Endocrinology 2005; 146:85-92.
    • (2005) Endocrinology , vol.146 , pp. 85-92
    • Fan, W.1    Yanase, T.2    Morinaga, H.3    Mu, Y.M.4    Nomura, M.5    Okabe, T.6
  • 33
    • 11144262773 scopus 로고    scopus 로고
    • Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation
    • Chen F, Harrison LE. Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation. Int J Biochem Cell Biol 2005; 37:645-654.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 645-654
    • Chen, F.1    Harrison, L.E.2
  • 35
    • 0242526756 scopus 로고    scopus 로고
    • Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta
    • Chen F, Wang M, O'Connor JP, He M, Tripathi T, Harrison LE. Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta. J Cell Biochem 2003; 90:732-744.
    • (2003) J Cell Biochem , vol.90 , pp. 732-744
    • Chen, F.1    Wang, M.2    O'Connor, J.P.3    He, M.4    Tripathi, T.5    Harrison, L.E.6
  • 36
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
    • Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, et al. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 1999; 274:32048-32054.
    • (1999) J Biol Chem , vol.274 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3    Vanden Berghe, W.4    Peters, J.M.5    Gonzalez, F.J.6
  • 37
    • 33644864102 scopus 로고    scopus 로고
    • PPAR-gamma agonists as regulators of microglial activation and brain inflammation
    • Bernardo A, Minghetti L. PPAR-gamma agonists as regulators of microglial activation and brain inflammation. Curr Pharm Des 2006; 12:93-109.
    • (2006) Curr Pharm Des , vol.12 , pp. 93-109
    • Bernardo, A.1    Minghetti, L.2
  • 38
    • 0038352039 scopus 로고    scopus 로고
    • 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia
    • Park EJ, Park SY, Joe EH, Jou I. 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. J Biol Chem 2003; 278:14747-14752.
    • (2003) J Biol Chem , vol.278 , pp. 14747-14752
    • Park, E.J.1    Park, S.Y.2    Joe, E.H.3    Jou, I.4
  • 40
    • 1042286477 scopus 로고    scopus 로고
    • Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: Effects on lipid homeostasis, inflammation, and atherosclerosis
    • Ricote M, Valledor AF, Glass CK. Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis. Arterioscler Thromb Vasc Biol 2004; 24:230-239.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 230-239
    • Ricote, M.1    Valledor, A.F.2    Glass, C.K.3
  • 41
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999; 20:649-688.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 42
    • 1542283630 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • Mandard S, Muller M, Kersten S. Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci 2004; 61:393-416.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 393-416
    • Mandard, S.1    Muller, M.2    Kersten, S.3
  • 43
    • 0037072826 scopus 로고    scopus 로고
    • Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells
    • Wang N, Verna L, Chen NG, Chen J, Li H, Forman BM, Stemerman MB. Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells. J Biol Chem 2002; 277:34176-34181.
    • (2002) J Biol Chem , vol.277 , pp. 34176-34181
    • Wang, N.1    Verna, L.2    Chen, N.G.3    Chen, J.4    Li, H.5    Forman, B.M.6    Stemerman, M.B.7
  • 44
    • 0001297403 scopus 로고    scopus 로고
    • Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT
    • Yang XY, Wang LH, Chen T, Hodge DR, Resau JH, DaSilva L, Farrar WL. Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT. J Biol Chem 2000; 275:4541-4544.
    • (2000) J Biol Chem , vol.275 , pp. 4541-4544
    • Yang, X.Y.1    Wang, L.H.2    Chen, T.3    Hodge, D.R.4    Resau, J.H.5    DaSilva, L.6    Farrar, W.L.7
  • 45
    • 0035139943 scopus 로고    scopus 로고
    • Hostile takeovers: Viral appropriation of the NF-kappaB pathway
    • Hiscott J, Kwon H, Genin P. Hostile takeovers: viral appropriation of the NF-kappaB pathway. J Clin Invest 2001; 107:143-151.
    • (2001) J Clin Invest , vol.107 , pp. 143-151
    • Hiscott, J.1    Kwon, H.2    Genin, P.3
  • 46
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages
    • Chinetti G, GriglioS, Antonucci M, Torra IP, Delerive P, Majd Z, et al. Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. J Biol Chem 1998; 273:25573-25580.
    • (1998) J Biol Chem , vol.273 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3    Torra, I.P.4    Delerive, P.5    Majd, Z.6
  • 47
    • 0034693323 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B
    • Chung SW, Kang BY, Kim SH, Pak YK, Cho D, Trinchieri G, Kim TS. Oxidized low-density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B. J Biol Chem 2000; 275:32681-32687.
    • (2000) J Biol Chem , vol.275 , pp. 32681-32687
    • Chung, S.W.1    Kang, B.Y.2    Kim, S.H.3    Pak, Y.K.4    Cho, D.5    Trinchieri, G.6    Kim, T.S.7
  • 48
    • 15744388341 scopus 로고    scopus 로고
    • A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation
    • Barboric M, Peterlin BM. A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation. PLoS Biol 2005; 3:e76.
    • (2005) PLoS Biol , vol.3
    • Barboric, M.1    Peterlin, B.M.2
  • 49
    • 14544272384 scopus 로고    scopus 로고
    • Phosphorylation of PPARs: From molecular characterization to physiological relevance
    • Diradourian C, GirardJ, PegorierJP. Phosphorylation of PPARs: from molecular characterization to physiological relevance. Biochimie 2005; 87:33-38.
    • (2005) Biochimie , vol.87 , pp. 33-38
    • Diradourian, C.1    GirardJ2    PegorierJP3
  • 50
    • 25144519803 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: An example of nongenomic signaling
    • Gardner OS, Dewar BJ, Graves LM. Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: an example of nongenomic signaling. Mol Pharmacol 2005; 68:933-941.
    • (2005) Mol Pharmacol , vol.68 , pp. 933-941
    • Gardner, O.S.1    Dewar, B.J.2    Graves, L.M.3
  • 51
    • 33645112691 scopus 로고    scopus 로고
    • The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)
    • Peraza MA, Burdick AD, Marin HE, Gonzalez FJ, Peters JM. The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol Sci 2006; 90:269-295.
    • (2006) Toxicol Sci , vol.90 , pp. 269-295
    • Peraza, M.A.1    Burdick, A.D.2    Marin, H.E.3    Gonzalez, F.J.4    Peters, J.M.5
  • 52
    • 33646524699 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and inflammation
    • Moraes LA, Piqueras L, Bishop-Bailey D. Peroxisome proliferator-activated receptors and inflammation. Pharmacol Ther 2006; 110:371-385.
    • (2006) Pharmacol Ther , vol.110 , pp. 371-385
    • Moraes, L.A.1    Piqueras, L.2    Bishop-Bailey, D.3
  • 53
    • 0037090141 scopus 로고    scopus 로고
    • Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis
    • Poluektova LY, Munn DH, Persidsky Y, Gendelman HE. Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis. J Immunol 2002; 168:3941-3949.
    • (2002) J Immunol , vol.168 , pp. 3941-3949
    • Poluektova, L.Y.1    Munn, D.H.2    Persidsky, Y.3    Gendelman, H.E.4
  • 54
    • 0026685175 scopus 로고
    • Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription
    • Liu J, Perkins ND, Schmid RM, Nabel GJ. Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription. J Virol 1992; 66:3883-3887.
    • (1992) J Virol , vol.66 , pp. 3883-3887
    • Liu, J.1    Perkins, N.D.2    Schmid, R.M.3    Nabel, G.J.4
  • 55
    • 0034892960 scopus 로고    scopus 로고
    • Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation
    • West MJ, Lowe AD, Karn J. Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation. J Virol 2001; 75:8524-8537.
    • (2001) J Virol , vol.75 , pp. 8524-8537
    • West, M.J.1    Lowe, A.D.2    Karn, J.3
  • 56
    • 0034628628 scopus 로고    scopus 로고
    • Occurrence of additional NF-kappaB-binding motifs in the long terminal repeat region of South African HIV type 1 subtype C isolates
    • Hunt G, Tiemessen CT. Occurrence of additional NF-kappaB-binding motifs in the long terminal repeat region of South African HIV type 1 subtype C isolates. AIDS Res Hum Retroviruses 2000; 16:305-306.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 305-306
    • Hunt, G.1    Tiemessen, C.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.