-
1
-
-
79951539518
-
Prolyl isomerase pin1 protects mice from endotoxin shock
-
Akiyama H, Misawa T, Ono M, Uchida C, Uchida T. 2011. Prolyl isomerase pin1 protects mice from endotoxin shock. PloS ONE 6:e14656.
-
(2011)
PloS ONE
, vol.6
-
-
Akiyama, H.1
Misawa, T.2
Ono, M.3
Uchida, C.4
Uchida, T.5
-
2
-
-
26844546178
-
Protein acetylation regulates both PU.1 transactivation and Ig kappa 3′ enhancer activity
-
Bai YC, Srinivasan L, Perkins L, Atchison ML. 2005. Protein acetylation regulates both PU.1 transactivation and Ig kappa 3′ enhancer activity. J Immunol 175:5160-5169.
-
(2005)
J Immunol
, vol.175
, pp. 5160-5169
-
-
Bai, Y.C.1
Srinivasan, L.2
Perkins, L.3
Atchison, M.L.4
-
3
-
-
84855411949
-
The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice
-
Barberi TJ, Dunkle A, He YW, Racioppi L, Means AR. 2012. The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice. PloS ONE 7:e29808.
-
(2012)
PloS ONE
, vol.7
-
-
Barberi, T.J.1
Dunkle, A.2
He, Y.W.3
Racioppi, L.4
Means, A.R.5
-
4
-
-
77953282048
-
The transcription factor PU.1 controls dendritic cell development and Flt3 cytokine receptor expression in a dose-dependent manner
-
Carotta S, Dakic A, D'Amico A, Pang SH, Greig KT, Nutt SL, Wu L. 2010. The transcription factor PU.1 controls dendritic cell development and Flt3 cytokine receptor expression in a dose-dependent manner. Immunity 32:628-641.
-
(2010)
Immunity
, vol.32
, pp. 628-641
-
-
Carotta, S.1
Dakic, A.2
D'Amico, A.3
Pang, S.H.4
Greig, K.T.5
Nutt, S.L.6
Wu, L.7
-
5
-
-
0142124320
-
Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor
-
Dahl R, Walsh JC, Lancki D, Laslo P, Iyer SR, Singh H, Simon MC. 2003. Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor. Nat Immunol 4:1029-1036.
-
(2003)
Nat Immunol
, vol.4
, pp. 1029-1036
-
-
Dahl, R.1
Walsh, J.C.2
Lancki, D.3
Laslo, P.4
Iyer, S.R.5
Singh, H.6
Simon, M.C.7
-
6
-
-
18644373047
-
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
-
Dakic A, Metcalf D, Di Rago L, Mifsud S, Wu L, Nutt SL. 2005. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J Exp Med 201:1487-1502.
-
(2005)
J Exp Med
, vol.201
, pp. 1487-1502
-
-
Dakic, A.1
Metcalf, D.2
Di Rago, L.3
Mifsud, S.4
Wu, L.5
Nutt, S.L.6
-
7
-
-
33847104543
-
Is PU.1 a dosage-sensitive regulator of haemopoietic lineage commitment and leukaemogenesis
-
Dakic A, Wu L, Nutt SL. 2007. Is PU.1 a dosage-sensitive regulator of haemopoietic lineage commitment and leukaemogenesis? Trends Immunol 28:108-114.
-
(2007)
Trends Immunol
, vol.28
, pp. 108-114
-
-
Dakic, A.1
Wu, L.2
Nutt, S.L.3
-
8
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
DeKoter RP, Singh H. 2000. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288:1439-1441.
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
DeKoter, R.P.1
Singh, H.2
-
9
-
-
43449088839
-
Phosphorylation-specific prolyl isomerase Pin1 as a new diagnostic and therapeutic target for cancer
-
Finn G, Lu KP. 2008. Phosphorylation-specific prolyl isomerase Pin1 as a new diagnostic and therapeutic target for cancer. Curr Cancer Drug Targets 8:223-229.
-
(2008)
Curr Cancer Drug Targets
, vol.8
, pp. 223-229
-
-
Finn, G.1
Lu, K.P.2
-
10
-
-
77957069984
-
Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene
-
Forsberg M, Carlen M, Meletis K, Yeung MS, Barnabe-Heider F, Persson MA, Aarum J, Frisen J. 2010. Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene. Proc Natl Acad Sci USA 107:14657-14661.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14657-14661
-
-
Forsberg, M.1
Carlen, M.2
Meletis, K.3
Yeung, M.S.4
Barnabe-Heider, F.5
Persson, M.A.6
Aarum, J.7
Frisen, J.8
-
11
-
-
35348875999
-
Transcriptional control of granulocyte and monocyte development
-
Friedman AD. 2007. Transcriptional control of granulocyte and monocyte development. Oncogene 26:6816-6828.
-
(2007)
Oncogene
, vol.26
, pp. 6816-6828
-
-
Friedman, A.D.1
-
12
-
-
0033619755
-
Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest
-
Fujimori F, Takahashi K, Uchida C, Uchida T. 1999. Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem Biophys Res Commun 265:658-663.
-
(1999)
Biochem Biophys Res Commun
, vol.265
, pp. 658-663
-
-
Fujimori, F.1
Takahashi, K.2
Uchida, C.3
Uchida, T.4
-
13
-
-
22144447520
-
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype
-
Growney JD, Shigematsu H, Li Z, Lee BH, Adeisperger J, Rowan R, Curley DP, Kutok JL, Akashi K, Williams IR, Speck NA, Gilliland DG. 2005. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood 106:494-504.
-
(2005)
Blood
, vol.106
, pp. 494-504
-
-
Growney, J.D.1
Shigematsu, H.2
Li, Z.3
Lee, B.H.4
Adeisperger, J.5
Rowan, R.6
Curley, D.P.7
Kutok, J.L.8
Akashi, K.9
Williams, I.R.10
Speck, N.A.11
Gilliland, D.G.12
-
14
-
-
78650941326
-
Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3
-
Guo H, Friedman AD. 2011. Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3. J Biol Chem 286:208-215.
-
(2011)
J Biol Chem
, vol.286
, pp. 208-215
-
-
Guo, H.1
Friedman, A.D.2
-
15
-
-
84861074498
-
Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis
-
Guo H, Ma O, Speck NA, Friedman AD. 2012. Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis. Blood 119:4408-4418.
-
(2012)
Blood
, vol.119
, pp. 4408-4418
-
-
Guo, H.1
Ma, O.2
Speck, N.A.3
Friedman, A.D.4
-
16
-
-
24044535104
-
The Runx1 transcription factor controls CSF-1-dependent and -independent growth and survival of macrophages
-
Himes SR, Cronau S, Mulford C, Hume DA. 2005. The Runx1 transcription factor controls CSF-1-dependent and -independent growth and survival of macrophages. Oncogene 24:5278-5286.
-
(2005)
Oncogene
, vol.24
, pp. 5278-5286
-
-
Himes, S.R.1
Cronau, S.2
Mulford, C.3
Hume, D.A.4
-
17
-
-
35648987137
-
The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis
-
Hoogenkamp M, Krysinska H, Ingram R, Huang G, Barlow R, Clarke D, Ebralidze A, Zhang P, Tagoh H, Cockerill PN, Tenen DG, Bonifer C. 2007. The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis. Mol Cell Biol 27:7425-7438.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7425-7438
-
-
Hoogenkamp, M.1
Krysinska, H.2
Ingram, R.3
Huang, G.4
Barlow, R.5
Clarke, D.6
Ebralidze, A.7
Zhang, P.8
Tagoh, H.9
Cockerill, P.N.10
Tenen, D.G.11
Bonifer, C.12
-
18
-
-
67651111994
-
Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program
-
Hoogenkamp M, Lichtinger M, Krysinska H, Lancrin C, Clarke D, Williamson A, et al. Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program. Blood 2009; 114:299-309.
-
(2009)
Blood
, vol.114
, pp. 299-309
-
-
Hoogenkamp, M.1
Lichtinger, M.2
Krysinska, H.3
Lancrin, C.4
Clarke, D.5
Williamson, A.6
-
19
-
-
37549052500
-
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis
-
Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG. 2008. PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet 40:51-60.
-
(2008)
Nat Genet
, vol.40
, pp. 51-60
-
-
Huang, G.1
Zhang, P.2
Hirai, H.3
Elf, S.4
Yan, X.5
Chen, Z.6
Koschmieder, S.7
Okuno, Y.8
Dayaram, T.9
Growney, J.D.10
Shivdasani, R.A.11
Gilliland, D.G.12
Speck, N.A.13
Nimer, S.D.14
Tenen, D.G.15
-
20
-
-
13244277465
-
Runx1/AML-1 ranks as a master regulator of adult hematopoiesis
-
Ichikawa M, Asai T, Chiba S, Kurokawa M, Ogawa S. 2004a. Runx1/AML-1 ranks as a master regulator of adult hematopoiesis. Cell Cycle 3:722-724.
-
(2004)
Cell Cycle
, vol.3
, pp. 722-724
-
-
Ichikawa, M.1
Asai, T.2
Chiba, S.3
Kurokawa, M.4
Ogawa, S.5
-
21
-
-
2342451948
-
AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
-
Ichikawa M, Asai T, Saito T, Seo S, Yamazaki I, Yamagata T, Mitani K, Chiba S, Ogawa S, Kurokawa M, Hirai H. 2004b. AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis. Nat Med 10:299-304.
-
(2004)
Nat Med
, vol.10
, pp. 299-304
-
-
Ichikawa, M.1
Asai, T.2
Saito, T.3
Seo, S.4
Yamazaki, I.5
Yamagata, T.6
Mitani, K.7
Chiba, S.8
Ogawa, S.9
Kurokawa, M.10
Hirai, H.11
-
22
-
-
34250214880
-
Myeloid lineage commitment from the hematopoietic stem cell
-
Iwasaki H, Akashi K. 2007. Myeloid lineage commitment from the hematopoietic stem cell. Immunity 26:726-740.
-
(2007)
Immunity
, vol.26
, pp. 726-740
-
-
Iwasaki, H.1
Akashi, K.2
-
23
-
-
84861878908
-
Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression
-
Jin H, Li L, Xu J, Zhen FH, Zhu L, Liu PP, Zhang MJ, Zhang WQ, Wen ZL. 2012. Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood 119:5239-5249.
-
(2012)
Blood
, vol.119
, pp. 5239-5249
-
-
Jin, H.1
Li, L.2
Xu, J.3
Zhen, F.H.4
Zhu, L.5
Liu, P.P.6
Zhang, M.J.7
Zhang, W.Q.8
Wen, Z.L.9
-
24
-
-
0037089229
-
Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease
-
Jundt F, Kley K, Anagnostopoulos I, Prosting KS, Greiner A, Mathas S, Scheidereit C, Wirth T, Stein H, Dorken B. 2002. Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease. Blood 99:3060-3062.
-
(2002)
Blood
, vol.99
, pp. 3060-3062
-
-
Jundt, F.1
Kley, K.2
Anagnostopoulos, I.3
Prosting, K.S.4
Greiner, A.5
Mathas, S.6
Scheidereit, C.7
Wirth, T.8
Stein, H.9
Dorken, B.10
-
25
-
-
0035500922
-
Loss of PU.1 expression following inhibition of histone deacetylases
-
Laribee RN, Klemsz MJ. 2001. Loss of PU.1 expression following inhibition of histone deacetylases. J Immunol 167:5160-5166.
-
(2001)
J Immunol
, vol.167
, pp. 5160-5166
-
-
Laribee, R.N.1
Klemsz, M.J.2
-
26
-
-
33747196725
-
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
-
Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, Gantner BN, Dinner AR, Singh H. 2006. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 126:755-766.
-
(2006)
Cell
, vol.126
, pp. 755-766
-
-
Laslo, P.1
Spooner, C.J.2
Warmflash, A.3
Lancki, D.W.4
Lee, H.J.5
Sciammas, R.6
Gantner, B.N.7
Dinner, A.R.8
Singh, H.9
-
27
-
-
79957614245
-
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells (vol 117, pg 2827, 2011)
-
Leddin M. 2011. Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells (vol 117, pg 2827, 2011). Blood 117:5783.
-
(2011)
Blood
, vol.117
, pp. 5783
-
-
Leddin, M.1
-
28
-
-
80053304845
-
Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease
-
Lee TH, Pastorino L, Lu KP. 2011. Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease. Expert Rev Mol Med 13:e21.
-
(2011)
Expert Rev Mol Med
, vol.13
-
-
Lee, T.H.1
Pastorino, L.2
Lu, K.P.3
-
29
-
-
33847070442
-
The role of chromatin during transcription
-
Li B, Carey M, Workman JL. 2007. The role of chromatin during transcription. Cell 128:707-719.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
30
-
-
0035892121
-
Regulation of the PU.1 gene by distal elements
-
Li YL, Okuno Y, Zhang P, Radomska HS, Chen HM, Iwasaki H, Akashi K, Klemsz MJ, McKercher SR, Maki RA, Tenen DG. 2001. Regulation of the PU.1 gene by distal elements. Blood 98:2958-2965.
-
(2001)
Blood
, vol.98
, pp. 2958-2965
-
-
Li, Y.L.1
Okuno, Y.2
Zhang, P.3
Radomska, H.S.4
Chen, H.M.5
Iwasaki, H.6
Akashi, K.7
Klemsz, M.J.8
McKercher, S.R.9
Maki, R.A.10
Tenen, D.G.11
-
32
-
-
33745002500
-
Targeting carcinogenesis: A role for the prolyl isomerase Pin1
-
Lu KP, Suizu F, Zhou XZ, Finn G, Lam P, Wulf G. 2006. Targeting carcinogenesis: A role for the prolyl isomerase Pin1? Mol Carcinog 45:397-402.
-
(2006)
Mol Carcinog
, vol.45
, pp. 397-402
-
-
Lu, K.P.1
Suizu, F.2
Zhou, X.Z.3
Finn, G.4
Lam, P.5
Wulf, G.6
-
33
-
-
35448945269
-
The prolyl isomerase PI N1: A pivotal new twist in phosphorylation signalling and disease
-
Lu KP, Zhou XZ. 2007. The prolyl isomerase PI N1: A pivotal new twist in phosphorylation signalling and disease. Nat Rev Mol Cell Biol 8:904-916.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 904-916
-
-
Lu, K.P.1
Zhou, X.Z.2
-
35
-
-
0242549003
-
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
-
McKercher SR, Torbett BE, Anderson KL, Henkel GW, Vestal DJ, Baribault H, Klemsz M, Feeney AJ, Wu GE, Paige CJ, Maki RA. 1996. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. Embo J 15:5647-5658.
-
(1996)
Embo J
, vol.15
, pp. 5647-5658
-
-
McKercher, S.R.1
Torbett, B.E.2
Anderson, K.L.3
Henkel, G.W.4
Vestal, D.J.5
Baribault, H.6
Klemsz, M.7
Feeney, A.J.8
Wu, G.E.9
Paige, C.J.10
Maki, R.A.11
-
36
-
-
33645725968
-
Loss of PU.1: One of the many roads to myeloid leukemia
-
Metcalf D. 2006. Loss of PU.1: One of the many roads to myeloid leukemia. Cell Cycle 5:673-674.
-
(2006)
Cell Cycle
, vol.5
, pp. 673-674
-
-
Metcalf, D.1
-
37
-
-
31944450531
-
Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia
-
Metcalf D, Dakic A, Mifsud S, Di Rago L, Wu L, Nutt S. 2006. Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia. Proc Natl Acad Sci USA 103:1486-1491.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1486-1491
-
-
Metcalf, D.1
Dakic, A.2
Mifsud, S.3
Di Rago, L.4
Wu, L.5
Nutt, S.6
-
38
-
-
0023839919
-
Spi-1 is a putative oncogene in virally induced murine erythroleukaemias
-
Moreau-Gachelin F, Tavitian A, Tambourin P. 1988. Spi-1 is a putative oncogene in virally induced murine erythroleukaemias. Nature 331:277-280.
-
(1988)
Nature
, vol.331
, pp. 277-280
-
-
Moreau-Gachelin, F.1
Tavitian, A.2
Tambourin, P.3
-
39
-
-
0029978734
-
Spi-1/PU.1 transgenic mice develop multistep erythroleukemias
-
MoreauGachelin F, Wendling F, Molina T, Denis N, Titeux M, Grimber G, Briand P, Vainchenker W, Tavitian A. 1996. Spi-1/PU.1 transgenic mice develop multistep erythroleukemias. Mol Cell Biol 16:2453-2463.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2453-2463
-
-
MoreauGachelin, F.1
Wendling, F.2
Molina, T.3
Denis, N.4
Titeux, M.5
Grimber, G.6
Briand, P.7
Vainchenker, W.8
Tavitian, A.9
-
40
-
-
33645734361
-
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression
-
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG. 2006. ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression. Blood 107:3330-3338.
-
(2006)
Blood
, vol.107
, pp. 3330-3338
-
-
Mueller, B.U.1
Pabst, T.2
Fos, J.3
Petkovic, V.4
Fey, M.F.5
Asou, N.6
Buergi, U.7
Tenen, D.G.8
-
41
-
-
0037369257
-
Heterozygous PU.1 mutations are associated with acute myeloid leukemia
-
Mueller BU, Pabst T, Osato M, Asou N, Johansen LM, Minden MD, Behre G, Hiddemann W, Ito Y, Tenen DG. 2003. Heterozygous PU.1 mutations are associated with acute myeloid leukemia. Blood 101:2074.
-
(2003)
Blood
, vol.101
, pp. 2074
-
-
Mueller, B.U.1
Pabst, T.2
Osato, M.3
Asou, N.4
Johansen, L.M.5
Minden, M.D.6
Behre, G.7
Hiddemann, W.8
Ito, Y.9
Tenen, D.G.10
-
42
-
-
0032146794
-
PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors
-
Nerlov C, Graf T. 1998. PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev 12:2403-2412.
-
(1998)
Genes Dev
, vol.12
, pp. 2403-2412
-
-
Nerlov, C.1
Graf, T.2
-
43
-
-
0030061554
-
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda T, vanDeursen J, Hiebert SW, Grosveld G, Downing JR. 1996. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84:321-330.
-
(1996)
Cell
, vol.84
, pp. 321-330
-
-
Okuda, T.1
vanDeursen, J.2
Hiebert, S.W.3
Grosveld, G.4
Downing, J.R.5
-
44
-
-
20144368117
-
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element
-
Okuno Y, Huang G, Rosenbauer F, Evans EK, Radomska HS, Iwasaki H, Akashi K, Moreau-Gachelin F, Li Y, Zhang P, Gottgens B, Tenen DG. 2005. Potential autoregulation of transcription factor PU.1 by an upstream regulatory element. Mol Cell Biol 25:2832-2845.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2832-2845
-
-
Okuno, Y.1
Huang, G.2
Rosenbauer, F.3
Evans, E.K.4
Radomska, H.S.5
Iwasaki, H.6
Akashi, K.7
Moreau-Gachelin, F.8
Li, Y.9
Zhang, P.10
Gottgens, B.11
Tenen, D.G.12
-
45
-
-
32544445732
-
AML1 deletion in adult mice causes splenomegaly and lymphomas
-
Putz G, Rosner A, Nuesslein I, Schmitz N, Buchholz F. 2006. AML1 deletion in adult mice causes splenomegaly and lymphomas. Oncogene 25:929-939.
-
(2006)
Oncogene
, vol.25
, pp. 929-939
-
-
Putz, G.1
Rosner, A.2
Nuesslein, I.3
Schmitz, N.4
Buchholz, F.5
-
46
-
-
29444440721
-
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1
-
Rosenbauer F, Owens BM, Yu L, Tumang JR, Steidl U, Kutok JL, Clayton LK, Wagner K, Scheller M, Iwasaki H, Liu CH, Hackanson B, Akashi K, Leutz A, Rothstein TL, Plass C, Tenen DG. 2006. Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1. Nat Genet 38:27-37.
-
(2006)
Nat Genet
, vol.38
, pp. 27-37
-
-
Rosenbauer, F.1
Owens, B.M.2
Yu, L.3
Tumang, J.R.4
Steidl, U.5
Kutok, J.L.6
Clayton, L.K.7
Wagner, K.8
Scheller, M.9
Iwasaki, H.10
Liu, C.H.11
Hackanson, B.12
Akashi, K.13
Leutz, A.14
Rothstein, T.L.15
Plass, C.16
Tenen, D.G.17
-
47
-
-
33846622099
-
Transcription factors in myeloid development: balancing differentiation with transformation
-
Rosenbauer F, Tenen DG. 2007. Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol 7:105-117.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 105-117
-
-
Rosenbauer, F.1
Tenen, D.G.2
-
48
-
-
2642519463
-
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1
-
Rosenbauer F, Wagner K, Kutok JL, Iwasaki H, Le Beau MM, Okuno Y, Akashi K, Fiering S, Tenen DG. 2004. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1. Nat Genet 36:624-630.
-
(2004)
Nat Genet
, vol.36
, pp. 624-630
-
-
Rosenbauer, F.1
Wagner, K.2
Kutok, J.L.3
Iwasaki, H.4
Le Beau, M.M.5
Okuno, Y.6
Akashi, K.7
Fiering, S.8
Tenen, D.G.9
-
49
-
-
0030611964
-
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
-
Scott EW, Fisher RC, Olson MC, Kehrli EW, Simon MC, Singh H. 1997. PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 6:437-447.
-
(1997)
Immunity
, vol.6
, pp. 437-447
-
-
Scott, E.W.1
Fisher, R.C.2
Olson, M.C.3
Kehrli, E.W.4
Simon, M.C.5
Singh, H.6
-
50
-
-
0032830638
-
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
-
Song WJ, Sullivan MG, Legare RD, Hutchings S, Tan XL, Kufrin D, Ratajczak J, Resende IC, Haworth C, Hock R, Loh M, Felix C, Roy DC, Busque L, Kurnit D, Willman C, Gewirtz AM, Speck NA, Bushweller JH, Li FP, Gardiner K, Poncz M, Maris JM, Gilliland DG. 1999. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet 23:166-175.
-
(1999)
Nat Genet
, vol.23
, pp. 166-175
-
-
Song, W.J.1
Sullivan, M.G.2
Legare, R.D.3
Hutchings, S.4
Tan, X.L.5
Kufrin, D.6
Ratajczak, J.7
Resende, I.C.8
Haworth, C.9
Hock, R.10
Loh, M.11
Felix, C.12
Roy, D.C.13
Busque, L.14
Kurnit, D.15
Willman, C.16
Gewirtz, A.M.17
Speck, N.A.18
Bushweller, J.H.19
Li, F.P.20
Gardiner, K.21
Poncz, M.22
Maris, J.M.23
Gilliland, D.G.24
more..
-
51
-
-
84876860619
-
Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells
-
Staber PB, Zhang P, Ye M, Welner RS, Nombela-Arrieta C, Bach C, Kerenyi M, Bartholdy BA, Zhang H, Alberich-Jorda M, Lee S, Yang H, Ng F, Zhang J, Leddin M, Silberstein LE, Hoefler G, Orkin SH, Gottgens B, Rosenbauer F, Huang G, Tenen DG. 2013. Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells. Mol Cell 49:934-946.
-
(2013)
Mol Cell
, vol.49
, pp. 934-946
-
-
Staber, P.B.1
Zhang, P.2
Ye, M.3
Welner, R.S.4
Nombela-Arrieta, C.5
Bach, C.6
Kerenyi, M.7
Bartholdy, B.A.8
Zhang, H.9
Alberich-Jorda, M.10
Lee, S.11
Yang, H.12
Ng, F.13
Zhang, J.14
Leddin, M.15
Silberstein, L.E.16
Hoefler, G.17
Orkin, S.H.18
Gottgens, B.19
Rosenbauer, F.20
Huang, G.21
Tenen, D.G.22
more..
-
52
-
-
33750447052
-
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells
-
Steidl U, Rosenbauer F, Verhaak RGW, Gu XS, Ebralidze A, Otu HH, Klippel S, Steidl C, Bruns I, Costa DB, Wagner K, Aivado M, Kobbe G, Valk PJM, Passegue E, Libermann TA, Delwel R, Tenen DG. 2006. Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells. Nat Genet 38:1269-1277.
-
(2006)
Nat Genet
, vol.38
, pp. 1269-1277
-
-
Steidl, U.1
Rosenbauer, F.2
Verhaak, R.G.W.3
Gu, X.S.4
Ebralidze, A.5
Otu, H.H.6
Klippel, S.7
Steidl, C.8
Bruns, I.9
Costa, D.B.10
Wagner, K.11
Aivado, M.12
Kobbe, G.13
Valk, P.J.M.14
Passegue, E.15
Libermann, T.A.16
Delwel, R.17
Tenen, D.G.18
-
53
-
-
38949155149
-
Prolyl isomerase, Pin1: New findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer's disease
-
Takahashi K, Uchida C, Shin RW, Shimazaki K, Uchida T. 2008. Prolyl isomerase, Pin1: New findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer's disease. Cell Mol Life Sci 65:359-375.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 359-375
-
-
Takahashi, K.1
Uchida, C.2
Shin, R.W.3
Shimazaki, K.4
Uchida, T.5
-
54
-
-
65649122716
-
Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1
-
Tatara Y, Lin YC, Bamba Y, Mori T, Uchida T. 2009. Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1. Biochem Biophys Res Commun 384:394-398.
-
(2009)
Biochem Biophys Res Commun
, vol.384
, pp. 394-398
-
-
Tatara, Y.1
Lin, Y.C.2
Bamba, Y.3
Mori, T.4
Uchida, T.5
-
55
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG. 2003. Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 3:89-101.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
56
-
-
24644482422
-
Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha
-
Walter MJ, Park JS, Ries RE, Lau SK, McLellan M, Jaeger S, Wilson RK, Mardis ER, Ley TJ. 2005. Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha. Proc Natl Acad Sci USA 102:12513-12518.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12513-12518
-
-
Walter, M.J.1
Park, J.S.2
Ries, R.E.3
Lau, S.K.4
McLellan, M.5
Jaeger, S.6
Wilson, R.K.7
Mardis, E.R.8
Ley, T.J.9
-
57
-
-
68649116713
-
Post-translational modifications of Runx1 regulate its activity in the cell
-
Wang L, Huang G, Zhao X, Hatlen MA, Vu L, Liu F, Nimer SD. 2009. Post-translational modifications of Runx1 regulate its activity in the cell. Blood Cells Mol Dis 43:30-34.
-
(2009)
Blood Cells Mol Dis
, vol.43
, pp. 30-34
-
-
Wang, L.1
Huang, G.2
Zhao, X.3
Hatlen, M.A.4
Vu, L.5
Liu, F.6
Nimer, S.D.7
-
58
-
-
34247490735
-
PIN1, the cell cycle and cancer
-
Yeh ES, Means AR. 2007. PIN1, the cell cycle and cancer. Nat Rev Cancer 7:381-388.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 381-388
-
-
Yeh, E.S.1
Means, A.R.2
-
59
-
-
84883042547
-
Pin1-mediated Runx2 modification is critical for skeletal development
-
Yoon WJ, Islam R, Cho YD, Woo KM, Baek JH, Uchida T, Komori T, van Wijnen A, Stein JL, Lian JB, Stein GS, Choi JY, Bae SC, Ryoo HM. 2013. Pin1-mediated Runx2 modification is critical for skeletal development. J Cell Physiol 228:2377-2385.
-
(2013)
J Cell Physiol
, vol.228
, pp. 2377-2385
-
-
Yoon, W.J.1
Islam, R.2
Cho, Y.D.3
Woo, K.M.4
Baek, J.H.5
Uchida, T.6
Komori, T.7
van Wijnen, A.8
Stein, J.L.9
Lian, J.B.10
Stein, G.S.11
Choi, J.Y.12
Bae, S.C.13
Ryoo, H.M.14
-
60
-
-
84860606995
-
The significance of low PU.1 expression in patients with acute promyelocytic leukemia
-
Zhu XH, Zhang H, Qian MX, Zhao XJ, Yang WT, Wang P, Zhang J, Wang KK. 2012. The significance of low PU.1 expression in patients with acute promyelocytic leukemia. J Hematol Oncol 5:22.
-
(2012)
J Hematol Oncol
, vol.5
, pp. 22
-
-
Zhu, X.H.1
Zhang, H.2
Qian, M.X.3
Zhao, X.J.4
Yang, W.T.5
Wang, P.6
Zhang, J.7
Wang, K.K.8
|