Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

Nature Genetics

Volumn 38, Issue 1, 2006, Pages 27-37

  Rosenbauer, Frank ^a,b   Owens, Bronwyn M ^a   Yu, Li ^c   Tumang, Joseph R ^d   Steidl, Ulrich ^a   Kutok, Jeffery L ^e   Clayton, Linda K ^f   Wagner, Katharina ^a,g   Scheller, Marina ^b   Iwasaki, Hiromi ^f   Liu, Chunhui ^c   Hackanson, Björn ^c   Akashi, Koichi ^f   Leutz, Achim ^b   Rothstein, Thomas L ^d   Plass, Christoph ^c   Tenen, Daniel G ^a  

^a HARVARD STEM CELL INSTITUTE   (United States)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c OHIO STATE UNIVERSITY   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; GENE PRODUCT; TRANSCRIPTION FACTOR PU 1; WNT PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CANCER INHIBITION; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CELL TRANSFORMATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE; GENE DELETION; GENE SILENCING; GENETIC CODE; GENETIC TRANSCRIPTION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LYMPHOID CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SFPI1 GENE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIGENS, THY-1; B-LYMPHOCYTES; BETA CATENIN; CELL TRANSFORMATION, NEOPLASTIC; DNA METHYLATION; GENE EXPRESSION REGULATION; LYMPHOCYTES; LYMPHOMA, T-CELL; MICE; MICE, SCID; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; STEM CELLS; TCF TRANSCRIPTION FACTORS; THYMUS GLAND; TRANS-ACTIVATORS; WNT PROTEINS;

ANIMALIA;

EID: 29444440721     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1679     Document Type: Article

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