Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis

Blood

Volumn 119, Issue 19, 2012, Pages 4408-4418

  Guo, Hong ^a   Ma, Ou ^a   Speck, Nancy A ^b   Friedman, Alan D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 1; CCAAT ENHANCER BINDING PROTEIN ALPHA; CELL PROTEIN; HISTONE H3; MESSENGER RNA; PROTEIN CEBPA; PROTEIN P300; STEM CELL FACTOR; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX1A; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ARTICLE; BINDING SITE; BONE MARROW CELL; CONTROLLED STUDY; GENE CONTROL; GENE DELETION; GENE MUTATION; GENETIC CONSERVATION; GRANULOCYTE PRECURSOR; GRANULOPOIESIS; HEMATOPOIESIS; HISTONE MODIFICATION; LEUKEMOGENESIS; MONOCYTE; MONOPOIESIS; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTION REGULATION;

EID: 84861074498     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-12-397091     Document Type: Article

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