AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

Nature Medicine

Volumn 10, Issue 3, 2004, Pages 299-304

  Ichikawa, Motoshi ^a   Asai, Takashi ^a   Saito, Toshiki ^a   Yamamoto, Go ^a   Seo, Sachiko ^a   Yamazaki, Ieharu ^b   Yamagata, Tetsuya ^a,d   Mitani, Kinuko ^c   Chiba, Shigeru ^a   Hirai, Hisamaru ^a   Ogawa, Seishi ^a   Kurokawa, Mineo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Inoue Memorial Hospital   (Japan)

^c DOKKYO MEDICAL UNIVERSITY   (Japan)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; TRANSCRIPTION FACTOR RUNX1; DNA BINDING PROTEIN; ONCOPROTEIN; RUNX1 PROTEIN, HUMAN; RUNX1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; EMBRYO DEATH; FLOW CYTOMETRY; GENE EXPRESSION; GENE TARGETING; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; KNOCKOUT MOUSE; LYMPHOCYTE DIFFERENTIATION; MEGAKARYOCYTE; MOUSE; MYELODYSPLASTIC SYNDROME; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; THROMBOCYTE DYSFUNCTION; ADULT; ANIMAL; BONE MARROW CELL; CELL DIFFERENTIATION; CELL LINEAGE; CELL SIZE; CYTOLOGY; GENETICS; HUMAN; LYMPHOCYTE; METABOLISM; METHODOLOGY; MOUSE STRAIN; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALIA;

ADULT; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SIZE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA-BINDING PROTEINS; GENE TARGETING; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; LYMPHOCYTES; MEGAKARYOCYTES; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS;

EID: 2342451948     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm997     Document Type: Article

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