-
1
-
-
33749521608
-
Latest development in drug discovery on G protein-coupled receptors
-
17073697 1:CAS:528:DC%2BD28XhtVamsLvO
-
Lundstrom K (2006) Latest development in drug discovery on G protein-coupled receptors. Curr Protein Pept Sci 7(5):465-470
-
(2006)
Curr Protein Pept Sci
, vol.7
, Issue.5
, pp. 465-470
-
-
Lundstrom, K.1
-
2
-
-
0038491435
-
Functional characterization of human receptors for short-chain fatty acids and their role in polymorphonuclear cell activation
-
12711604
-
Le Poul E et al (2003) Functional characterization of human receptors for short-chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 278(28):25481-25489
-
(2003)
J Biol Chem
, vol.278
, Issue.28
, pp. 25481-25489
-
-
Le Poul, E.1
-
3
-
-
0038363378
-
The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short-chain carboxylic acids
-
12496283 1:CAS:528:DC%2BD3sXit1Kgsbc%3D
-
Brown AJ et al (2003) The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short-chain carboxylic acids. J Biol Chem 278(13):11312-11319
-
(2003)
J Biol Chem
, vol.278
, Issue.13
, pp. 11312-11319
-
-
Brown, A.J.1
-
4
-
-
0023276469
-
Short-chain fatty acids in human large intestine, portal, hepatic and venous blood
-
3678950 1:STN:280:DyaL1c%2Fls1CrsA%3D%3D
-
Cummings JH et al (1987) Short-chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28(10):1221-1227
-
(1987)
Gut
, vol.28
, Issue.10
, pp. 1221-1227
-
-
Cummings, J.H.1
-
5
-
-
80054980812
-
Regulation of inflammation by short-chain fatty acids
-
22254083 1:CAS:528:DC%2BC3MXhsVKju7nJ
-
Vinolo MA et al (2011) Regulation of inflammation by short-chain fatty acids. Nutrients 3(10):858-876
-
(2011)
Nutrients
, vol.3
, Issue.10
, pp. 858-876
-
-
Vinolo, M.A.1
-
6
-
-
57049182455
-
Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents
-
18796545 1:CAS:528:DC%2BD1cXhsVWku77P
-
Zhou J et al (2008) Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents. Am J Physiol Endocrinol Metab 295(5):E1160-E1166
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, Issue.5
-
-
Zhou, J.1
-
7
-
-
33846827097
-
Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat
-
1:CAS:528:DC%2BD28Xht1WjsLzN
-
Keenan MJ et al (2006) Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat. Obesity (Silver Spring) 14(9):1523-1534
-
(2006)
Obesity (Silver Spring)
, vol.14
, Issue.9
, pp. 1523-1534
-
-
Keenan, M.J.1
-
8
-
-
84867404198
-
Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
-
22976799 1:CAS:528:DC%2BC38XhsFSgtb7K
-
Bindels LB et al (2012) Gut microbiota-derived propionate reduces cancer cell proliferation in the liver. Br J Cancer 107(8):1337-1344
-
(2012)
Br J Cancer
, vol.107
, Issue.8
, pp. 1337-1344
-
-
Bindels, L.B.1
-
9
-
-
34347223232
-
Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: A study with relevance to inflammatory bowel disease
-
17569118 1:CAS:528:DC%2BD2sXot1antrs%3D
-
Tedelind S et al (2007) Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease. World J Gastroenterol 13(20):2826-2832
-
(2007)
World J Gastroenterol
, vol.13
, Issue.20
, pp. 2826-2832
-
-
Tedelind, S.1
-
10
-
-
84855206779
-
Regulation of inflammatory responses by the commensal microbiota
-
21825084
-
Marsland BJ (2012) Regulation of inflammatory responses by the commensal microbiota. Thorax 67(1):93-94
-
(2012)
Thorax
, vol.67
, Issue.1
, pp. 93-94
-
-
Marsland, B.J.1
-
11
-
-
0036252352
-
The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation
-
11983830 1:CAS:528:DC%2BD38XjvFSnsbg%3D
-
Hinnebusch BF et al (2002) The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation. J Nutr 132(5):1012-1017
-
(2002)
J Nutr
, vol.132
, Issue.5
, pp. 1012-1017
-
-
Hinnebusch, B.F.1
-
12
-
-
84876018174
-
GPR43/FFA2: Physiopathological relevance and therapeutic prospects
-
23489932 1:CAS:528:DC%2BC3sXjvVOrsrk%3D
-
Bindels LB, Dewulf EM, Delzenne NM (2013) GPR43/FFA2: physiopathological relevance and therapeutic prospects. Trends Pharmacol Sci 34(4):226-232
-
(2013)
Trends Pharmacol Sci
, vol.34
, Issue.4
, pp. 226-232
-
-
Bindels, L.B.1
Dewulf, E.M.2
Delzenne, N.M.3
-
13
-
-
0037453280
-
Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids
-
12684041 1:CAS:528:DC%2BD3sXis12gsbc%3D
-
Nilsson NE et al (2003) Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. Biochem Biophys Res Commun 303(4):1047-1052
-
(2003)
Biochem Biophys Res Commun
, vol.303
, Issue.4
, pp. 1047-1052
-
-
Nilsson, N.E.1
-
14
-
-
0742305675
-
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
-
14722361 1:CAS:528:DC%2BD2cXhtFSkt74%3D
-
Xiong Y et al (2004) Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 101(4):1045-1050
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.4
, pp. 1045-1050
-
-
Xiong, Y.1
-
15
-
-
57049170465
-
Fatty acid binding receptors and their physiological role in type 2 diabetes
-
1:CAS:528:DC%2BD1cXhsFCqtL7P
-
Swaminath G (2008) Fatty acid binding receptors and their physiological role in type 2 diabetes. Arch Pharm (Weinheim) 341(12):753-761
-
(2008)
Arch Pharm (Weinheim)
, vol.341
, Issue.12
, pp. 753-761
-
-
Swaminath, G.1
-
16
-
-
51449119654
-
Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions
-
18812643
-
Tazoe H et al (2008) Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions. J Physiol Pharmacol 59(Suppl 2):251-262
-
(2008)
J Physiol Pharmacol
, vol.59
, Issue.SUPPL. 2
, pp. 251-262
-
-
Tazoe, H.1
-
17
-
-
84870361150
-
Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3
-
23066016 1:CAS:528:DC%2BC38XhslGjs7fI
-
Hudson BD et al (2012) Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3. J Biol Chem 287(49):41195-41209
-
(2012)
J Biol Chem
, vol.287
, Issue.49
, pp. 41195-41209
-
-
Hudson, B.D.1
-
18
-
-
0037509909
-
Regulation of short-chain fatty acid production
-
12740060 1:CAS:528:DC%2BD3sXjslyhtLc%3D
-
Macfarlane S, Macfarlane GT (2003) Regulation of short-chain fatty acid production. Proc Nutr Soc 62(1):67-72
-
(2003)
Proc Nutr Soc
, vol.62
, Issue.1
, pp. 67-72
-
-
Macfarlane, S.1
Macfarlane, G.T.2
-
19
-
-
0021801223
-
Carbohydrate fermentation in the human colon and its relation to acetate concentrations in venous blood
-
3998144 1:CAS:528:DyaL2MXktVChs74%3D
-
Pomare EW, Branch WJ, Cummings JH (1985) Carbohydrate fermentation in the human colon and its relation to acetate concentrations in venous blood. J Clin Invest 75(5):1448-1454
-
(1985)
J Clin Invest
, vol.75
, Issue.5
, pp. 1448-1454
-
-
Pomare, E.W.1
Branch, W.J.2
Cummings, J.H.3
-
20
-
-
0032716189
-
De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption
-
10539756 1:CAS:528:DyaK1MXntFCgu70%3D
-
Siler SQ, Neese RA, Hellerstein MK (1999) De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption. Am J Clin Nutr 70(5):928-936
-
(1999)
Am J Clin Nutr
, vol.70
, Issue.5
, pp. 928-936
-
-
Siler, S.Q.1
Neese, R.A.2
Hellerstein, M.K.3
-
21
-
-
84867616398
-
High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
-
23091640 1:CAS:528:DC%2BC38Xhs1Wht7fO
-
Kim KA et al (2012) High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway. PLoS One 7(10):e47713
-
(2012)
PLoS One
, vol.7
, Issue.10
, pp. 47713
-
-
Kim, K.A.1
-
22
-
-
84865726183
-
Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine
-
22700822
-
de Wit N et al (2012) Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine. Am J Physiol Gastrointest Liver Physiol 303(5):G589-G599
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.303
, Issue.5
-
-
De Wit, N.1
-
23
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
19043404 1:CAS:528:DC%2BD1MXotlOlsw%3D%3D
-
Turnbaugh PJ et al (2009) A core gut microbiome in obese and lean twins. Nature 457(7228):480-484
-
(2009)
Nature
, vol.457
, Issue.7228
, pp. 480-484
-
-
Turnbaugh, P.J.1
-
24
-
-
84878579044
-
The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
-
23652017
-
Kimura I et al (2013) The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun 4:1829
-
(2013)
Nat Commun
, vol.4
, pp. 1829
-
-
Kimura, I.1
-
25
-
-
57349142454
-
Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2
-
18818303 1:CAS:528:DC%2BD1cXhsVGkt7fO
-
Lee T et al (2008) Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol 74(6):1599-1609
-
(2008)
Mol Pharmacol
, vol.74
, Issue.6
, pp. 1599-1609
-
-
Lee, T.1
-
26
-
-
72249086955
-
The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators
-
20005104
-
Wang Y et al (2010) The first synthetic agonists of FFA2: discovery and SAR of phenylacetamides as allosteric modulators. Bioorg Med Chem Lett 20(2):493-498
-
(2010)
Bioorg Med Chem Lett
, vol.20
, Issue.2
, pp. 493-498
-
-
Wang, Y.1
-
27
-
-
77957114912
-
Allosteric rescuing of loss-of-function FFAR2 mutations
-
20837008 1:CAS:528:DC%2BC3cXht1GjsrjI
-
Swaminath G et al (2010) Allosteric rescuing of loss-of-function FFAR2 mutations. FEBS Lett 584(19):4208-4214
-
(2010)
FEBS Lett
, vol.584
, Issue.19
, pp. 4208-4214
-
-
Swaminath, G.1
-
28
-
-
79959309348
-
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator
-
21498659 1:CAS:528:DC%2BC3MXosFajtLk%3D
-
Smith NJ et al (2011) Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol Pharmacol 80(1):163-173
-
(2011)
Mol Pharmacol
, vol.80
, Issue.1
, pp. 163-173
-
-
Smith, N.J.1
-
29
-
-
79953216793
-
Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: Identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3
-
21220428 1:CAS:528:DC%2BC3MXjsVyqs7k%3D
-
Schmidt J et al (2011) Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. J Biol Chem 286(12):10628-10640
-
(2011)
J Biol Chem
, vol.286
, Issue.12
, pp. 10628-10640
-
-
Schmidt, J.1
-
30
-
-
84879037150
-
Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor
-
23589301 1:CAS:528:DC%2BC3sXpsFansro%3D
-
Hudson BD et al (2013) Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor. J Biol Chem 288(24):17296-17312
-
(2013)
J Biol Chem
, vol.288
, Issue.24
, pp. 17296-17312
-
-
Hudson, B.D.1
-
33
-
-
74049124329
-
Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E(2) and cytokines
-
19938193 1:CAS:528:DC%2BD1MXhsFSmtbrF
-
Cox MA et al (2009) Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E(2) and cytokines. World J Gastroenterol 15(44):5549-5557
-
(2009)
World J Gastroenterol
, vol.15
, Issue.44
, pp. 5549-5557
-
-
Cox, M.A.1
-
34
-
-
83755225879
-
Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner
-
22178946 1:CAS:528:DC%2BC3MXhs1eltbnO
-
Cornall LM et al (2011) Diet-induced obesity up-regulates the abundance of GPR43 and GPR120 in a tissue specific manner. Cell Physiol Biochem 28(5):949-958
-
(2011)
Cell Physiol Biochem
, vol.28
, Issue.5
, pp. 949-958
-
-
Cornall, L.M.1
-
35
-
-
41049090425
-
Expression of the short-chain fatty acid receptor, GPR43, in the human colon
-
17899402 1:CAS:528:DC%2BD1cXjsFWrsbc%3D
-
Karaki S et al (2008) Expression of the short-chain fatty acid receptor, GPR43, in the human colon. J Mol Histol 39(2):135-142
-
(2008)
J Mol Histol
, vol.39
, Issue.2
, pp. 135-142
-
-
Karaki, S.1
-
36
-
-
27844440904
-
Acetate and propionate short-chain fatty acids stimulate adipogenesis via GPCR43
-
16123168 1:CAS:528:DC%2BD2MXht1Ogur%2FL
-
Hong YH et al (2005) Acetate and propionate short-chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology 146(12):5092-5099
-
(2005)
Endocrinology
, vol.146
, Issue.12
, pp. 5092-5099
-
-
Hong, Y.H.1
-
37
-
-
77952957384
-
Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short-chain fatty acids
-
20399779 1:CAS:528:DC%2BC3cXmsVOiu7k%3D
-
Zaibi MS et al (2010) Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short-chain fatty acids. FEBS Lett 584(11):2381-2386
-
(2010)
FEBS Lett
, vol.584
, Issue.11
, pp. 2381-2386
-
-
Zaibi, M.S.1
-
38
-
-
79960299449
-
Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARgamma-related adipogenesis in the white adipose tissue of high-fat diet-fed mice
-
21115338
-
Dewulf EM et al (2010) Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARgamma-related adipogenesis in the white adipose tissue of high-fat diet-fed mice. J Nutr Biochem 22(8):712-722
-
(2010)
J Nutr Biochem
, vol.22
, Issue.8
, pp. 712-722
-
-
Dewulf, E.M.1
-
39
-
-
79954435406
-
Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide
-
21113792 1:CAS:528:DC%2BC3MXjvVenurg%3D
-
Kaji I et al (2011) Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide. J Mol Histol 42(1):27-38
-
(2011)
J Mol Histol
, vol.42
, Issue.1
, pp. 27-38
-
-
Kaji, I.1
-
40
-
-
71849088409
-
Identification of transforming activity of free fatty acid receptor 2 by retroviral expression screening
-
19780758 1:CAS:528:DC%2BC3cXnvVKruw%3D%3D
-
Hatanaka H et al (2010) Identification of transforming activity of free fatty acid receptor 2 by retroviral expression screening. Cancer Sci 101(1):54-59
-
(2010)
Cancer Sci
, vol.101
, Issue.1
, pp. 54-59
-
-
Hatanaka, H.1
-
41
-
-
78650618692
-
G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer
-
20979106 1:CAS:528:DC%2BC3cXhsF2rtrjP
-
Tang Y et al (2011) G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer. Int J Cancer 128(4):847-856
-
(2011)
Int J Cancer
, vol.128
, Issue.4
, pp. 847-856
-
-
Tang, Y.1
-
42
-
-
57749112018
-
Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short-chain fatty acids
-
18801738 1:CAS:528:DC%2BD1cXhtlOjtLnE
-
Stoddart LA et al (2008) Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short-chain fatty acids. J Biol Chem 283(47):32913-32924
-
(2008)
J Biol Chem
, vol.283
, Issue.47
, pp. 32913-32924
-
-
Stoddart, L.A.1
-
43
-
-
84870373974
-
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs
-
22919070 1:CAS:528:DC%2BC38XhvVCgtrnO
-
Hudson BD et al (2012) Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs. FASEB J 26(12):4951-4965
-
(2012)
FASEB J
, vol.26
, Issue.12
, pp. 4951-4965
-
-
Hudson, B.D.1
-
44
-
-
33845345276
-
Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line
-
16887331 1:CAS:528:DC%2BD28Xhtlalt7jJ
-
Yonezawa T, Kobayashi Y, Obara Y (2007) Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line. Cell Signal 19(1):185-193
-
(2007)
Cell Signal
, vol.19
, Issue.1
, pp. 185-193
-
-
Yonezawa, T.1
Kobayashi, Y.2
Obara, Y.3
-
45
-
-
84864053102
-
Receptor-specific regulation of ERK1/2 activation by members of the "free fatty acid receptor" family
-
22712802 1:CAS:528:DC%2BC38XhtVClsrzI
-
Seljeset S, Siehler S (2012) Receptor-specific regulation of ERK1/2 activation by members of the "free fatty acid receptor" family. J Recept Signal Transduct Res 32(4):196-201
-
(2012)
J Recept Signal Transduct Res
, vol.32
, Issue.4
, pp. 196-201
-
-
Seljeset, S.1
Siehler, S.2
-
46
-
-
79958812655
-
SCFAs induce mouse neutrophil chemotaxis through the GPR43 receptor
-
21698257 1:CAS:528:DC%2BC3MXotVWjsL4%3D
-
Vinolo MA et al (2011) SCFAs induce mouse neutrophil chemotaxis through the GPR43 receptor. PLoS One 6(6):e21205
-
(2011)
PLoS One
, vol.6
, Issue.6
, pp. 21205
-
-
Vinolo, M.A.1
-
47
-
-
84866740088
-
Short-chain fatty acids suppress lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines through inhibition of NF-kappaB pathway in RAW264.7 cells
-
22669487 1:CAS:528:DC%2BC38XhtlGrurjF
-
Liu T et al (2012) Short-chain fatty acids suppress lipopolysaccharide- induced production of nitric oxide and proinflammatory cytokines through inhibition of NF-kappaB pathway in RAW264.7 cells. Inflammation 35(5):1676-1684
-
(2012)
Inflammation
, vol.35
, Issue.5
, pp. 1676-1684
-
-
Liu, T.1
-
48
-
-
73349123182
-
G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation
-
19917676 1:CAS:528:DC%2BD1MXhsVehtrrN
-
Sina C et al (2009) G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation. J Immunol 183(11):7514-7522
-
(2009)
J Immunol
, vol.183
, Issue.11
, pp. 7514-7522
-
-
Sina, C.1
-
49
-
-
19644367000
-
Activation and signaling of the p38 MAP kinase pathway
-
15686620 1:CAS:528:DC%2BD2MXkslGisb4%3D
-
Zarubin T, Han J (2005) Activation and signaling of the p38 MAP kinase pathway. Cell Res 15(1):11-18
-
(2005)
Cell Res
, vol.15
, Issue.1
, pp. 11-18
-
-
Zarubin, T.1
Han, J.2
-
50
-
-
70350666634
-
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
-
19865172 1:CAS:528:DC%2BD1MXhtlOjt7vI
-
Maslowski KM et al (2009) Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 461(7268):1282-1286
-
(2009)
Nature
, vol.461
, Issue.7268
, pp. 1282-1286
-
-
Maslowski, K.M.1
-
51
-
-
33646376658
-
Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine
-
16453106 1:CAS:528:DC%2BD28XjvFSgu7k%3D
-
Karaki S et al (2006) Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res 324(3):353-360
-
(2006)
Cell Tissue Res
, vol.324
, Issue.3
, pp. 353-360
-
-
Karaki, S.1
-
52
-
-
78751643126
-
- secretion and free fatty acid receptor 2 (FFA2, GPR43) expression in the guinea pig distal colon
-
20945073 1:CAS:528:DC%2BC3MXjsVGr
-
- secretion and free fatty acid receptor 2 (FFA2, GPR43) expression in the guinea pig distal colon. Pflugers Arch 461(1):141-152
-
(2011)
Pflugers Arch
, vol.461
, Issue.1
, pp. 141-152
-
-
Karaki, S.1
Kuwahara, A.2
-
53
-
-
0037405738
-
Short-chain fatty acids stimulate colonic transit via intraluminal 5-HT release in rats
-
12676748 1:CAS:528:DC%2BD3sXjvFGru7Y%3D
-
Fukumoto S et al (2003) Short-chain fatty acids stimulate colonic transit via intraluminal 5-HT release in rats. Am J Physiol Regul Integr Comp Physiol 284(5):R1269-R1276
-
(2003)
Am J Physiol Regul Integr Comp Physiol
, vol.284
, Issue.5
-
-
Fukumoto, S.1
-
54
-
-
84856509724
-
Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2
-
22190648 1:CAS:528:DC%2BC38XltVOlt7Y%3D
-
Tolhurst G et al (2012) Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes 61(2):364-371
-
(2012)
Diabetes
, vol.61
, Issue.2
, pp. 364-371
-
-
Tolhurst, G.1
-
55
-
-
77951792949
-
Immunopathogenesis of inflammatory bowel disease
-
Matricon J (2010) Immunopathogenesis of inflammatory bowel disease. Med Sci (Paris) 26(4):405-410
-
(2010)
Med Sci (Paris)
, vol.26
, Issue.4
, pp. 405-410
-
-
Matricon, J.1
-
56
-
-
0034109077
-
Obesity, insulin resistance and diabetes - A worldwide epidemic
-
10889785 1:CAS:528:DC%2BD3cXjs1Ogtbs%3D
-
Seidell JC (2000) Obesity, insulin resistance and diabetes - a worldwide epidemic. Br J Nutr 83(Suppl 1):S5-S8
-
(2000)
Br J Nutr
, vol.83
, Issue.SUPPL. 1
-
-
Seidell, J.C.1
-
57
-
-
0037167664
-
World Heart Day 2002: The international burden of cardiovascular disease: Responding to the emerging global epidemic
-
12270848
-
Bonow RO et al (2002) World Heart Day 2002: the international burden of cardiovascular disease: responding to the emerging global epidemic. Circulation 106(13):1602-1605
-
(2002)
Circulation
, vol.106
, Issue.13
, pp. 1602-1605
-
-
Bonow, R.O.1
-
58
-
-
80051986265
-
Globalization of diabetes: The role of diet, lifestyle, and genes
-
21617109
-
Hu FB (2011) Globalization of diabetes: the role of diet, lifestyle, and genes. Diabetes Care 34(6):1249-1257
-
(2011)
Diabetes Care
, vol.34
, Issue.6
, pp. 1249-1257
-
-
Hu, F.B.1
-
59
-
-
0030819249
-
Body mass index and mortality in a general population sample of men and women. The Buffalo health study
-
9400333 1:STN:280:DyaK1c%2Fmt1ylsw%3D%3D
-
Dorn JM et al (1997) Body mass index and mortality in a general population sample of men and women. The Buffalo health study. Am J Epidemiol 146(11):919-931
-
(1997)
Am J Epidemiol
, vol.146
, Issue.11
, pp. 919-931
-
-
Dorn, J.M.1
-
60
-
-
0033001612
-
Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality. A prospective population study
-
10099921 1:STN:280:DyaK1M7pvFKqtg%3D%3D
-
Rosengren A, Wedel H, Wilhelmsen L (1999) Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality. A prospective population study. Eur Heart J 20(4):269-277
-
(1999)
Eur Heart J
, vol.20
, Issue.4
, pp. 269-277
-
-
Rosengren, A.1
Wedel, H.2
Wilhelmsen, L.3
-
61
-
-
78650800467
-
Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet
-
20959533 1:CAS:528:DC%2BC3MXhvVSjsb0%3D
-
Bjursell M et al (2011) Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet. Am J Physiol Endocrinol Metab 300(1):E211-E220
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
, Issue.1
-
-
Bjursell, M.1
-
62
-
-
50449087891
-
Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids
-
18499755 1:CAS:528:DC%2BD1cXhtVKnu7vF
-
Ge H et al (2008) Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 149(9):4519-4526
-
(2008)
Endocrinology
, vol.149
, Issue.9
, pp. 4519-4526
-
-
Ge, H.1
-
63
-
-
33646917184
-
Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo
-
16696951 1:CAS:528:DC%2BD28Xltl2gt7k%3D
-
Nakano R et al (2006) Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo. Biochem Pharmacol 72(1):42-52
-
(2006)
Biochem Pharmacol
, vol.72
, Issue.1
, pp. 42-52
-
-
Nakano, R.1
-
64
-
-
36048950218
-
Adipogenesis and lipotoxicity: Role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1)
-
17903321
-
Medina-Gomez G, Gray S, Vidal-Puig A (2007) Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1). Public Health Nutr 10(10A):1132-1137
-
(2007)
Public Health Nutr
, vol.10
, Issue.10 A
, pp. 1132-1137
-
-
Medina-Gomez, G.1
Gray, S.2
Vidal-Puig, A.3
-
65
-
-
70350346153
-
GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors
-
19837462 1:CAS:528:DC%2BD1MXhtlCku7zM
-
Ahmed K, Tunaru S, Offermanns S (2009) GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors. Trends Pharmacol Sci 30(11):557-562
-
(2009)
Trends Pharmacol Sci
, vol.30
, Issue.11
, pp. 557-562
-
-
Ahmed, K.1
Tunaru, S.2
Offermanns, S.3
-
66
-
-
54349124808
-
Leptin regulates peripheral lipid metabolism primarily through central effects on food intake
-
18635658 1:CAS:528:DC%2BD1cXhtlWnsrrE
-
Prieur X et al (2008) Leptin regulates peripheral lipid metabolism primarily through central effects on food intake. Endocrinology 149(11):5432-5439
-
(2008)
Endocrinology
, vol.149
, Issue.11
, pp. 5432-5439
-
-
Prieur, X.1
-
67
-
-
8844255472
-
The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation
-
15556643 1:CAS:528:DC%2BD2cXhtVSrtLfF
-
Solinas G et al (2004) The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation. FEBS Lett 577(3):539-544
-
(2004)
FEBS Lett
, vol.577
, Issue.3
, pp. 539-544
-
-
Solinas, G.1
-
68
-
-
70350203976
-
Central leptin action improves skeletal muscle AKT, AMPK, and PGC1 alpha activation by hypothalamic PI3 K-dependent mechanism
-
19698760 1:CAS:528:DC%2BD1MXhtlWhtrrL
-
Roman EA et al (2010) Central leptin action improves skeletal muscle AKT, AMPK, and PGC1 alpha activation by hypothalamic PI3 K-dependent mechanism. Mol Cell Endocrinol 314(1):62-69
-
(2010)
Mol Cell Endocrinol
, vol.314
, Issue.1
, pp. 62-69
-
-
Roman, E.A.1
-
69
-
-
59049103288
-
Chronic leptin treatment stimulates lipid oxidation in immortalized and primary mouse skeletal muscle cells
-
19103304 1:CAS:528:DC%2BD1MXhsFOlu7k%3D
-
Akasaka Y et al (2009) Chronic leptin treatment stimulates lipid oxidation in immortalized and primary mouse skeletal muscle cells. Biochim Biophys Acta 1791(2):103-109
-
(2009)
Biochim Biophys Acta
, vol.1791
, Issue.2
, pp. 103-109
-
-
Akasaka, Y.1
-
70
-
-
79951813012
-
Leptin increases skeletal muscle lipoprotein lipase and postprandial lipid metabolism in mice
-
20494377
-
Donahoo WT et al (2010) Leptin increases skeletal muscle lipoprotein lipase and postprandial lipid metabolism in mice. Metabolism 60(3):438-443
-
(2010)
Metabolism
, vol.60
, Issue.3
, pp. 438-443
-
-
Donahoo, W.T.1
-
71
-
-
34247868983
-
Leptin stimulation of COXIV is impaired in obese skeletal muscle myotubes
-
McAinch AJ et al (2007) Leptin stimulation of COXIV is impaired in obese skeletal muscle myotubes. Obes Res Clin Pract 1(1):53-60
-
(2007)
Obes Res Clin Pract
, vol.1
, Issue.1
, pp. 53-60
-
-
McAinch, A.J.1
-
72
-
-
77956907521
-
The adipokine leptin increases skeletal muscle mass and significantly alters skeletal muscle miRNA expression profile in aged mice
-
20800581 1:CAS:528:DC%2BC3cXht1WltrjE
-
Hamrick MW et al (2010) The adipokine leptin increases skeletal muscle mass and significantly alters skeletal muscle miRNA expression profile in aged mice. Biochem Biophys Res Commun 400(3):379-383
-
(2010)
Biochem Biophys Res Commun
, vol.400
, Issue.3
, pp. 379-383
-
-
Hamrick, M.W.1
-
73
-
-
70149104583
-
Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice
-
19730740
-
Sainz N et al (2009) Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice. PLoS One 4(9):e6808
-
(2009)
PLoS One
, vol.4
, Issue.9
, pp. 6808
-
-
Sainz, N.1
-
74
-
-
74949143243
-
Narrative review: The role of leptin in human physiology: Emerging clinical applications
-
20083828
-
Kelesidis T et al (2010) Narrative review: the role of leptin in human physiology: emerging clinical applications. Ann Intern Med 152(2):93-100
-
(2010)
Ann Intern Med
, vol.152
, Issue.2
, pp. 93-100
-
-
Kelesidis, T.1
-
75
-
-
78049311283
-
Obesity and leptin resistance: Distinguishing cause from effect
-
20846876 1:CAS:528:DC%2BC3cXhtlKltL7L
-
Myers MG Jr et al (2010) Obesity and leptin resistance: distinguishing cause from effect. Trends Endocrinol Metab 21(11):643-651
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.11
, pp. 643-651
-
-
Myers Jr., M.G.1
-
76
-
-
77955881869
-
Adipokine profile and insulin sensitivity in formerly obese women subjected to bariatric surgery or diet-induced long-term caloric restriction
-
20576650
-
Mitterberger MC et al (2010) Adipokine profile and insulin sensitivity in formerly obese women subjected to bariatric surgery or diet-induced long-term caloric restriction. J Gerontol A Biol Sci Med Sci 65(9):915-923
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65
, Issue.9
, pp. 915-923
-
-
Mitterberger, M.C.1
-
77
-
-
33750578279
-
Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha
-
16936205 1:CAS:528:DC%2BD28XpsVOrurs%3D
-
Yoon MJ et al (2006) Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes 55(9):2562-2570
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2562-2570
-
-
Yoon, M.J.1
-
78
-
-
33644967119
-
The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity
-
1:CAS:528:DC%2BD28XisVans7s%3D
-
Dyck DJ, Heigenhauser GJ, Bruce CR (2006) The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity. Acta Physiol (Oxf) 186(1):5-16
-
(2006)
Acta Physiol (Oxf)
, vol.186
, Issue.1
, pp. 5-16
-
-
Dyck, D.J.1
Heigenhauser, G.J.2
Bruce, C.R.3
-
79
-
-
18844432308
-
Adiponectin and adiponectin receptors
-
15897298 1:CAS:528:DC%2BD2MXltVWru7c%3D
-
Kadowaki T, Yamauchi T (2005) Adiponectin and adiponectin receptors. Endocr Rev 26(3):439-451
-
(2005)
Endocr Rev
, vol.26
, Issue.3
, pp. 439-451
-
-
Kadowaki, T.1
Yamauchi, T.2
-
80
-
-
0036678916
-
Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women
-
12153737 1:CAS:528:DC%2BD38XmslSgu7g%3D
-
Matsubara M, Maruoka S, Katayose S (2002) Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. Eur J Endocrinol 147(2):173-180
-
(2002)
Eur J Endocrinol
, vol.147
, Issue.2
, pp. 173-180
-
-
Matsubara, M.1
Maruoka, S.2
Katayose, S.3
-
81
-
-
44949237971
-
Adiponectin and its association with insulin resistance and type 2 diabetes
-
18571119 1:CAS:528:DC%2BD1cXhtVGjsrvL
-
Sheng T, Yang K (2008) Adiponectin and its association with insulin resistance and type 2 diabetes. J Genet Genomics 35(6):321-326
-
(2008)
J Genet Genomics
, vol.35
, Issue.6
, pp. 321-326
-
-
Sheng, T.1
Yang, K.2
-
82
-
-
57049107346
-
Endocrine functions of adipose tissue: Focus on adiponectin
-
19046738 discussion 39-40
-
Sowers JR (2008) Endocrine functions of adipose tissue: focus on adiponectin. Clin Cornerstone 9(1):32-38 discussion 39-40
-
(2008)
Clin Cornerstone
, vol.9
, Issue.1
, pp. 32-38
-
-
Sowers, J.R.1
-
83
-
-
0024237258
-
Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans
-
3059816 1:CAS:528:DyaL1MXltFKgtg%3D%3D
-
Baron AD et al (1988) Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans. Am J Physiol 255(6 Pt 1):E769-E774
-
(1988)
Am J Physiol
, vol.255
, Issue.6 PART 1
-
-
Baron, A.D.1
-
84
-
-
0025047553
-
Skeletal muscle metabolism is a major determinant of resting energy expenditure
-
2243122 1:CAS:528:DyaK3cXmt1yguro%3D
-
Zurlo F et al (1990) Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 86(5):1423-1427
-
(1990)
J Clin Invest
, vol.86
, Issue.5
, pp. 1423-1427
-
-
Zurlo, F.1
-
85
-
-
0034467428
-
PPAR signaling in the control of cardiac energy metabolism
-
11282301 1:CAS:528:DC%2BD3MXitF2ktr0%3D
-
Barger PM, Kelly DP (2000) PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med 10(6):238-245
-
(2000)
Trends Cardiovasc Med
, vol.10
, Issue.6
, pp. 238-245
-
-
Barger, P.M.1
Kelly, D.P.2
-
86
-
-
0037117651
-
Adaptation and maladaptation of the heart in diabetes: Part II: Potential mechanisms
-
11956132 1:CAS:528:DC%2BD38XjvFakt70%3D
-
Young ME, McNulty P, Taegtmeyer H (2002) Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms. Circulation 105(15):1861-1870
-
(2002)
Circulation
, vol.105
, Issue.15
, pp. 1861-1870
-
-
Young, M.E.1
McNulty, P.2
Taegtmeyer, H.3
-
87
-
-
34248664707
-
Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters
-
16988889 1:CAS:528:DC%2BD2sXltFSrt78%3D
-
Coort SL et al (2007) Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: role of sarcolemmal substrate transporters. Mol Cell Biochem 299(1-2):5-18
-
(2007)
Mol Cell Biochem
, vol.299
, Issue.1-2
, pp. 5-18
-
-
Coort, S.L.1
-
88
-
-
27844457564
-
Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity
-
16141388 1:CAS:528:DC%2BD2MXht1OgurrI
-
Buchanan J et al (2005) Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity. Endocrinology 146(12):5341-5349
-
(2005)
Endocrinology
, vol.146
, Issue.12
, pp. 5341-5349
-
-
Buchanan, J.1
-
89
-
-
79957969004
-
Mitochondrial dysfunction in diabetic cardiomyopathy
-
21256163 1:CAS:528:DC%2BC3MXntV2lsLc%3D
-
Duncan JG (2011) Mitochondrial dysfunction in diabetic cardiomyopathy. Biochim Biophys Acta 1813(7):1351-1359
-
(2011)
Biochim Biophys Acta
, vol.1813
, Issue.7
, pp. 1351-1359
-
-
Duncan, J.G.1
-
90
-
-
0033668021
-
Lipid oxidation is reduced in obese human skeletal muscle
-
11052958 1:CAS:528:DC%2BD3cXotFaqs7w%3D
-
Kim JY et al (2000) Lipid oxidation is reduced in obese human skeletal muscle. Am J Physiol Endocrinol Metab 279(5):E1039-E1044
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
, Issue.5
-
-
Kim, J.Y.1
-
91
-
-
33646394578
-
Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: Role of intramuscular accumulation of lipid metabolites
-
16357064 1:CAS:528:DC%2BD28XltVWlt78%3D
-
Lee JS et al (2006) Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites. J Appl Physiol 100(5):1467-1474
-
(2006)
J Appl Physiol
, vol.100
, Issue.5
, pp. 1467-1474
-
-
Lee, J.S.1
-
92
-
-
77952090390
-
Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients
-
20333349 1:CAS:528:DC%2BC3cXlt1OmsrY%3D
-
Aguer C et al (2010) Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients. Diabetologia 53(6):1151-1163
-
(2010)
Diabetologia
, vol.53
, Issue.6
, pp. 1151-1163
-
-
Aguer, C.1
-
93
-
-
4544355465
-
Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36
-
15132977 1:CAS:528:DC%2BD2cXlslKktrY%3D
-
Bonen A et al (2004) Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36. FASEB J 18(10):1144-1146
-
(2004)
FASEB J
, vol.18
, Issue.10
, pp. 1144-1146
-
-
Bonen, A.1
-
94
-
-
0345305404
-
Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status
-
14602787 1:CAS:528:DC%2BD3sXptVynt7w%3D
-
Bruce CR et al (2003) Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. J Clin Endocrinol Metab 88(11):5444-5451
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.11
, pp. 5444-5451
-
-
Bruce, C.R.1
-
95
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
-
10342815 1:CAS:528:DyaK1MXjsFSgtr8%3D
-
Griffin ME et al (1999) Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 48(6):1270-1274
-
(1999)
Diabetes
, vol.48
, Issue.6
, pp. 1270-1274
-
-
Griffin, M.E.1
-
96
-
-
33745409264
-
Reduced insulin suppression of glucose appearance is related to susceptibility to dietary obesity in rats
-
9140029 1:CAS:528:DyaK2sXjtVSnuro%3D
-
Pagliassotti MJ et al (1997) Reduced insulin suppression of glucose appearance is related to susceptibility to dietary obesity in rats. Am J Physiol 272(4 Pt 2):R1264-R1270
-
(1997)
Am J Physiol
, vol.272
, Issue.4 PART 2
-
-
Pagliassotti, M.J.1
-
97
-
-
0035827642
-
MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression
-
11279172 1:CAS:528:DC%2BD3MXktlKgtbY%3D
-
Fujishiro M et al (2001) MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression. J Biol Chem 276(23):19800-19806
-
(2001)
J Biol Chem
, vol.276
, Issue.23
, pp. 19800-19806
-
-
Fujishiro, M.1
-
98
-
-
0035504158
-
GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: Potential activation of GLUT4 via p38 mitogen-activated protein kinase
-
11672439 1:CAS:528:DC%2BD3MXovVSisbw%3D
-
Somwar R et al (2001) GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase. Biochem J 359(Pt 3):639-649
-
(2001)
Biochem J
, vol.359
, Issue.PART 3
, pp. 639-649
-
-
Somwar, R.1
-
99
-
-
0033537853
-
An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes
-
10187787 1:CAS:528:DyaK1MXis1Gjtrs%3D
-
Sweeney G et al (1999) An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes. J Biol Chem 274(15):10071-10078
-
(1999)
J Biol Chem
, vol.274
, Issue.15
, pp. 10071-10078
-
-
Sweeney, G.1
-
100
-
-
66149135126
-
Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status
-
19190259 1:CAS:528:DC%2BD1MXlvFags7g%3D
-
Babraj JA et al (2009) Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status. Am J Physiol Endocrinol Metab 296(5):E1042-E1048
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.5
-
-
Babraj, J.A.1
-
101
-
-
20144372237
-
ERK1/2 inhibition prevents contraction-induced increase in plasma membrane FAT/CD36 content and FA uptake in rodent muscle
-
15916673 1:CAS:528:DC%2BD2MXkvVajsL4%3D
-
Turcotte LP, Raney MA, Todd MK (2005) ERK1/2 inhibition prevents contraction-induced increase in plasma membrane FAT/CD36 content and FA uptake in rodent muscle. Acta Physiol Scand 184(2):131-139
-
(2005)
Acta Physiol Scand
, vol.184
, Issue.2
, pp. 131-139
-
-
Turcotte, L.P.1
Raney, M.A.2
Todd, M.K.3
-
102
-
-
2342428466
-
Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner
-
14764603
-
de Alvaro C et al (2004) Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner. J Biol Chem 279(17):17070-17078
-
(2004)
J Biol Chem
, vol.279
, Issue.17
, pp. 17070-17078
-
-
De Alvaro, C.1
-
103
-
-
0037059330
-
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
-
11606564 1:CAS:528:DC%2BD38XnvFyjtQ%3D%3D
-
Aguirre V et al (2002) Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 277(2):1531-1537
-
(2002)
J Biol Chem
, vol.277
, Issue.2
, pp. 1531-1537
-
-
Aguirre, V.1
-
104
-
-
79953221811
-
Counter modulation of fatty acid-induced proinflammatory NFβB signalling in rat skeletal muscle cells by AMPK
-
21323644 1:CAS:528:DC%2BC3MXlt1Wnur8%3D
-
Green CJ et al (2011) Counter modulation of fatty acid-induced proinflammatory NFβB signalling in rat skeletal muscle cells by AMPK. Biochem J 435(2):463-474
-
(2011)
Biochem J
, vol.435
, Issue.2
, pp. 463-474
-
-
Green, C.J.1
-
105
-
-
33750877988
-
Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation
-
17003343 1:CAS:528:DC%2BD28XhtVGlsrbJ
-
Coll T et al (2006) Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation. Diabetes 55(10):2779-2787
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2779-2787
-
-
Coll, T.1
-
106
-
-
0034383952
-
The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
-
11101507 1:CAS:528:DC%2BD3MXjtF2htr4%3D
-
Bueno OF et al (2000) The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J 19(23):6341-6350
-
(2000)
EMBO J
, vol.19
, Issue.23
, pp. 6341-6350
-
-
Bueno, O.F.1
-
107
-
-
0033840752
-
Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy
-
10888249 1:CAS:528:DC%2BD3cXkvVOrs74%3D
-
Ueyama T et al (2000) Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy. J Mol Cell Cardiol 32(6):947-960
-
(2000)
J Mol Cell Cardiol
, vol.32
, Issue.6
, pp. 947-960
-
-
Ueyama, T.1
-
108
-
-
34249869321
-
Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes
-
17499232 1:CAS:528:DC%2BD2sXmt1ynt7Y%3D
-
Palanivel R et al (2007) Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes. Cardiovasc Res 75(1):148-157
-
(2007)
Cardiovasc Res
, vol.75
, Issue.1
, pp. 148-157
-
-
Palanivel, R.1
-
109
-
-
58849116697
-
Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice
-
1:CAS:528:DC%2BD1MXhtVWisLc%3D
-
Dong F, Ren J (2009) Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice. Obesity (Silver Spring) 17(2):262-268
-
(2009)
Obesity (Silver Spring)
, vol.17
, Issue.2
, pp. 262-268
-
-
Dong, F.1
Ren, J.2
-
110
-
-
33744925901
-
Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart
-
16415076 1:CAS:528:DC%2BD28XlvVektrc%3D
-
Fujioka D et al (2006) Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart. Am J Physiol Heart Circ Physiol 290(6):H2409-H2416
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, Issue.6
-
-
Fujioka, D.1
-
111
-
-
84859529626
-
Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism
-
22357961 1:CAS:528:DC%2BC38XkslCht7w%3D
-
Chai W et al (2012) Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism. Diabetes 61(4):888-896
-
(2012)
Diabetes
, vol.61
, Issue.4
, pp. 888-896
-
-
Chai, W.1
-
112
-
-
33646795007
-
Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts
-
16489128 1:CAS:528:DC%2BD28Xlt1eqtL8%3D
-
Zhao T et al (2006) Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J Pharmacol Exp Ther 317(3):1106-1113
-
(2006)
J Pharmacol Exp Ther
, vol.317
, Issue.3
, pp. 1106-1113
-
-
Zhao, T.1
-
113
-
-
3843089529
-
Gut hormones and the control of appetite
-
15358278 1:CAS:528:DC%2BD2cXmsVGisr8%3D
-
Small CJ, Bloom SR (2004) Gut hormones and the control of appetite. Trends Endocrinol Metab 15(6):259-263
-
(2004)
Trends Endocrinol Metab
, vol.15
, Issue.6
, pp. 259-263
-
-
Small, C.J.1
Bloom, S.R.2
-
114
-
-
0032005005
-
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
-
9449682 1:CAS:528:DyaK1cXosVagsg%3D%3D
-
Flint A et al (1998) Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 101(3):515-520
-
(1998)
J Clin Invest
, vol.101
, Issue.3
, pp. 515-520
-
-
Flint, A.1
-
115
-
-
39149140997
-
Gastrointestinal peptides controlling body weight homeostasis
-
18164707 1:CAS:528:DC%2BD1cXhslOisLk%3D
-
Mendieta-Zeron H, Lopez M, Dieguez C (2008) Gastrointestinal peptides controlling body weight homeostasis. Gen Comp Endocrinol 155(3):481-495
-
(2008)
Gen Comp Endocrinol
, vol.155
, Issue.3
, pp. 481-495
-
-
Mendieta-Zeron, H.1
Lopez, M.2
Dieguez, C.3
-
116
-
-
78149493266
-
Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure
-
21080957
-
Liu Q et al (2010) Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure. Cardiovasc Diabetol 9:76
-
(2010)
Cardiovasc Diabetol
, vol.9
, pp. 76
-
-
Liu, Q.1
-
117
-
-
0038727630
-
The gut hormone peptide YY regulates appetite
-
12851312 1:CAS:528:DC%2BD3sXmtVCkt7w%3D
-
Batterham RL, Bloom SR (2003) The gut hormone peptide YY regulates appetite. Ann N Y Acad Sci 994:162-168
-
(2003)
Ann N y Acad Sci
, vol.994
, pp. 162-168
-
-
Batterham, R.L.1
Bloom, S.R.2
-
118
-
-
33646865736
-
Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions
-
16687037
-
Ballantyne GH (2006) Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions. Obes Surg 16(5):651-658
-
(2006)
Obes Surg
, vol.16
, Issue.5
, pp. 651-658
-
-
Ballantyne, G.H.1
-
119
-
-
3242794268
-
PYY3-36 reinforces insulin action on glucose disposal in mice fed a high-fat diet
-
15277371
-
van den Hoek AM et al (2004) PYY3-36 reinforces insulin action on glucose disposal in mice fed a high-fat diet. Diabetes 53(8):1949-1952
-
(2004)
Diabetes
, vol.53
, Issue.8
, pp. 1949-1952
-
-
Van Den Hoek, A.M.1
-
120
-
-
33845970529
-
Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice
-
16940471
-
van den Hoek AM et al (2007) Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice. Am J Physiol Endocrinol Metab 292(1):E238-E245
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, Issue.1
-
-
Van Den Hoek, A.M.1
-
121
-
-
77953241787
-
Gut hormones: Emerging role in immune activation and inflammation
-
20408856 1:CAS:528:DC%2BC3cXps1entbs%3D
-
Khan WI, Ghia JE (2010) Gut hormones: emerging role in immune activation and inflammation. Clin Exp Immunol 161(1):19-27
-
(2010)
Clin Exp Immunol
, vol.161
, Issue.1
, pp. 19-27
-
-
Khan, W.I.1
Ghia, J.E.2
-
122
-
-
84856337834
-
5-HT(2C) receptor agonists and the control of appetite
-
22249823 1:CAS:528:DC%2BC38XhslCgu7zK
-
Halford JC, Harrold JA (2012) 5-HT(2C) receptor agonists and the control of appetite. Handb Exp Pharmacol 209:349-356
-
(2012)
Handb Exp Pharmacol
, vol.209
, pp. 349-356
-
-
Halford, J.C.1
Harrold, J.A.2
-
123
-
-
0033531943
-
Serotonin (5-Hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle
-
10224126 1:CAS:528:DyaK1MXjtFOlurs%3D
-
Hajduch E et al (1999) Serotonin (5-Hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle. J Biol Chem 274(19):13563-13568
-
(1999)
J Biol Chem
, vol.274
, Issue.19
, pp. 13563-13568
-
-
Hajduch, E.1
-
124
-
-
49349115112
-
Effects of olanzapine on glucose transport, proliferation and survival in C2C12 myoblasts
-
18514390 1:CAS:528:DC%2BD1cXhtVagu7vP
-
Tulipano G, Spano P, Cocchi D (2008) Effects of olanzapine on glucose transport, proliferation and survival in C2C12 myoblasts. Mol Cell Endocrinol 292(1-2):42-49
-
(2008)
Mol Cell Endocrinol
, vol.292
, Issue.1-2
, pp. 42-49
-
-
Tulipano, G.1
Spano, P.2
Cocchi, D.3
-
125
-
-
15444368875
-
Serotonin (5-HT) drugs: Effects on appetite expression and use for the treatment of obesity
-
15777190 1:CAS:528:DC%2BD2MXisVSqu74%3D
-
Halford JC et al (2005) Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity. Curr Drug Targets 6(2):201-213
-
(2005)
Curr Drug Targets
, vol.6
, Issue.2
, pp. 201-213
-
-
Halford, J.C.1
-
126
-
-
84872565579
-
One-month serotonin infusion results in a prolonged fall in blood pressure in the deoxycorticosterone acetate (DOCA) salt hypertensive rat
-
23336053 1:CAS:528:DC%2BC38XhtlGjtrrM
-
Davis RP et al (2013) One-month serotonin infusion results in a prolonged fall in blood pressure in the deoxycorticosterone acetate (DOCA) salt hypertensive rat. ACS Chem Neurosci 4(1):141-148
-
(2013)
ACS Chem Neurosci
, vol.4
, Issue.1
, pp. 141-148
-
-
Davis, R.P.1
-
127
-
-
84876416957
-
Human 5-HT(4) receptor stimulation in atria of transgenic mice
-
23307014 1:CAS:528:DC%2BC3sXls12rt7k%3D
-
Gergs U et al (2013) Human 5-HT(4) receptor stimulation in atria of transgenic mice. Naunyn Schmiedebergs Arch Pharmacol 386(5):357-367
-
(2013)
Naunyn Schmiedebergs Arch Pharmacol
, vol.386
, Issue.5
, pp. 357-367
-
-
Gergs, U.1
|