ERK1/2 inhibition prevents contraction-induced increase in plasma membrane FAT/CD36 content and FA uptake in rodent muscle

Acta Physiologica Scandinavica

Volumn 184, Issue 2, 2005, Pages 131-139

  Turcotte, L P ^a   Raney, M A ^a   Todd, M K ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

AMP activated protein kinase; Electrical stimulation; Fatty acid metabolism; Glucose uptake; Hindlimb perfusion; PD 98059

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CD36 ANTIGEN; FATTY ACID; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PALMITIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FATTY ACID TRANSPORT; GLUCOSE TRANSPORT; MALE; MUSCLE CONTRACTION; MUSCLE PERFUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD36; BLOTTING, WESTERN; BODY WEIGHT; CELL MEMBRANE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY ACIDS; GLUCOSE; HINDLIMB; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE CONTRACTION; MUSCLE, SKELETAL; OXYGEN; PALMITATES; PHOSPHORYLATION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 20144372237     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-201X.2005.01445.x     Document Type: Article

References (39)

1. Bonen, A., Bonen, A, Dyck, DJ, Ibrahimi, A & Abumrad, NA. 1999. Muscle contractile activity increases fatty acid metabolism and transport and FAT/CD36. Am J Physiol Endocrinol Metab 276, E642-E649.
2. Bonen, A., Luiken, J.J.P.P., Arumugam, Y., Glatz, J.F.C. & Tandon, N.N. 2000a. Acute regulation of fatty acid uptake involves the cellular redistribution of fatty acid translocase. J Biol Chem 275, 14501-14508.
3. Bonen, A., Luiken, J.J.F.P., Dyck, D.J. et al. 2000b. Increased palmitate transport and oxidation in skeletal muscles of transgenic mice that overexpress fatty acid translocase (FAT/ CD36). FASEB J 14, A200.
4. Bonen, A., Benton, C.R., Campbell, S.E. et al. 2003. Plasmalemmal fatty acid transport is regulated in heart and skeletal muscle by contraction, insulin and leptin, and in obesity and diabetes. Acta Physiol Scand 178, 347-356.
5. Chen, H.C., Bandyopadhyay, G., Sajan, M.P. et al. 2002. Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport. J Biol Chem 277, 23554-23562.
6. Coburn, C.T., Knapp, F.F. Jr, Febbraio, M., Beets, A.L., Silverstein, R.L. & Abumrad, N.A. 2000. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J Biol Chem 275, 32523-32529.
7. Donsmark, M., Langfort, J., Holm, C., Ploug, T. & Galbo, H. 2003. Contractions activate hormone-sensitive lipase in rat muscle by protein kinase C and mitogen-activated protein kinase. J Physiol 550.3, 845-854.
8. Greenberg, A.S., Shen, W.-J., Muliro, K. et al 2001. Stimulation of lipolysis and hormone-sensitive lipase via the extra-cellular signal-regulated kinase pathway. J Biol Chem 276, 45456-45461.
9. Hajri, T & Abumrad, N.A. 2002. Fatty acid transport across membranes relevance to nutrition and metabolic pathology. Annu Rev Nutr 22, 383-415.
10. Harmon, C.M., Luce, P., Beth, A.H. & Abumrad, N.A. 1991. Labeling of adipocyte membranes by sulfo-N-succinimidyl derivatives of long-chain fatty acids: Inhibition of fatty acid transport. J Membrane Biol 121, 261-268.
11. Hayashi, T., Hirshman, M.F., Kurth, E.J., Winder, W.W. & Goodyear, L.J. 1998. Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 47, 1369-1373.
12. Hayashi, T., Hirshman, M.F., Dufresne, S.D. & Goodyear, L.J. 1999. Skeletal muscle contractile activity in vitro stimulates mitogen-activated protein kinase signaling. Am J Physiol 277, C701-C707.
13. Hutber, C.A., Hardie, D.G. & Winder, W.W. 1997. Electrical stimulation inactivates muscle acetyl CoA carboxylase and increases AMP-activated protein kinase. Am J Phyiol Endocrinol Metab 272, E262-E266.
14. Ibrahimi, A., Bonen, A., Blinn, W.D. et al. 1999. Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem 274, 26761-26766.
15. Jorgensen, S.B., Viollet, B., Andreelli, F. et al. 2004. Knockout of the α2 but not α1 5′-AMP-activated protein kinase isoform abolishes 5-aminoimidazole4-carboxamide-1-β-4-ribofuranoside- but not contraction-induced glucose uptake in skeletal muscle. J Biol Chem 279, 1070-1079.
16. Luiken, J.J.F.P., Turcotte, L.P. & Bonen, A. 1999. Protein-mediated palmitate uptake and expression of fatty acid transport proteins in heart giant vesicles. J Lipid Res 40, 1007-1016.
17. Luiken, J.J.F.P., Dyck, D.J., Han, X.X. et al. 2002. Insulin induces the translocation of the fatty acid transporter FAT/CD36 to the plasma membrane. Am J Physiol Endocrinol Metab 282, E491-E495.
18. Luiken, J.J.F.P., Coort, S.L.M., Willems, J. et al. 2003. Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling. Diabetes 52, 1627-1643.
19. Martineau, L.C. & Gardiner, P.F. 2001. Insight into skeletal muscle mechanotransduction: MAPK activation is quantitatively related to tension. J Appl Physiol 91, 693-702.
20. Merrill, G.F., Kurth, E.J., Hardie, D.G. & Winder, W.W. 1997. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol 273, E1107-E1112.
21. Mu, J., Brozinick, J.T. Jr, Valladares, O., Bucan, M., Birnbaum, M.J. 2001. A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell 7, 1085-1094.
22. Raney, M.A., Yee, A.J., Todd, M.K. & Turcotte, L.P. 2005. AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low intensity muscle contraction. Am J Physiol Endocrinol Metab 288, E592-E598.
23. Richter, E.A., Vistisen, B., Maarbjerg, S.J., Sajan, M., Farese, R.V. & Kiens, B. 2004. Differential effect of bicycling exercise intensity on activity and phosphorylation of atypical protein kinase C and extracellular signal-regulated protein kinase in skeletal muscle. J Physiol 560, 909-918.
24. Ryder, J.W., Fahlman, R., Wallberg-Henriksson, H., Alessi, D.R., Krook, A. & Zierath, J.R. 2000. Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement of the mitogen- and stress-activated protein kinase 1. J Biol Chem 275, 1457-1462.
25. Sakamoto, K. & Goodyear, L.J. 2002. Invited review: intracellular signaling in contracting skeletal muscle. J Appl Physiol 93, 369-383.
26. Tucker, M.Z. & Turcotte, L.P. 2002. Brief food restriction increases FA oxidation and glycogen synthesis under insulin-stimulated conditions. Am J Physiol Regul Integr Comp Physiol 282, R1210-R1218.
27. Turcotte, L.P., Richter, E.A. & Kiens, B. 1992. Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans. Am J Physiol 262, E791-E799.
28. Turcotte, L.P., Petry, C. Kiens, B. & Richter, E.A. 1998. Contraction-induced increase in Vmax of palmitate uptake and oxidation in perfused skeletal muscle. J Appl Physiol 84, 1788-1794.
29. Turcotte, L.P., Swenberger, J.R., Tucker, M.Z. & Yee, A.J. 1999. Training-induced elevation in FABP(PM) is associated with increased palmitate use in contracting muscle. J Appl Physiol 87, 285-293.
30. Turcotte, L.P., Swenberger, J.R., Tucker, M.Z. & Yee, A.J. 2001. Increased fatty acid uptake and altered fatty acid metabolism in insulin-resistant muscle of obese Zucker rats. Diabetes 50, 1389-1396.
31. Widegren, U., Jiang, X.J., Krook, A. et al. 1998. Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle. FASEB J 12, 1379-1389.
32. Widegren, U., Wretman, C., Lionikas, A., Hedin, G. & Henriksson, J. 2000. Influence of exercise intensity on ERK/MAP kinase signalling in human skeletal muscle. Pflugers Arch 441, 317-322.
33. Widegren, U., Ryder, J.W. & Zierath, J.R. 2001. Mitogen-activated protein kinase signal transduction in skeletal muscle: effects of exercise and muscle contraction. Acta Physiol Scand 172, 227-238.
34. Williamson, D., Gallagher, P., Harber, M., Hollon, C. & Trappe, S. 2003. Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. J Physiol 547, 977-987.
35. Winder, W.W. 1998. Malonyl-CoA-regulator of fatty acid oxidation in muscle during exercise. Exerc Sport Set Rev 26, 117-132.
36. Winder, W.W. & Hardie, D.G. 1996. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol 270, E299-304.
37. Wojtaszewski, J.F.P., Lynge, J., Jakobsen, A.B., Goodyear, L.J. & Richter, E.A. 1999. Differential regulation of MAP kinase by contraction and insulin in skeletal muscle: metabolic implications. Am J Physiol 277, E724-E732.
38. Wojtaszewski, J.P.P., Nielsen, J.N., Jorgensen, S.B., Frosig, C., Birk, J.B. & Richter, E.A. 2003. Transgenic models - a scientific tool to understand exercise-induced metabolism: the regulatory role of AMPK (5′-AMP-activated protein kinase) in glucose transport and glycogen synthase activity in skeletal muscle. Biochem Soc Trans 31, 1290-1294.
39. Zheng, D., MacLean, P.S., Pohnert, S.C. et al. 2001. Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase. J Appl Physiol 91, 1073-1083.