-
1
-
-
84860210262
-
Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease
-
Swerdlow, R.H. (2012) Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease. Antioxid. Redox Signal., 16, 1434-1455.
-
(2012)
Antioxid. Redox Signal.
, vol.16
, pp. 1434-1455
-
-
Swerdlow, R.H.1
-
2
-
-
33751406988
-
Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment
-
Valla, J., Schneider, L., Niedzielko, T., Coon, K.D., Caselli, R., Sabbagh, M.N., Ahern, G.L., Baxter, L., Alexander, G., Walker, D.G. et al. (2006) Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment. Mitochondrion, 6, 323-330.
-
(2006)
Mitochondrion
, vol.6
, pp. 323-330
-
-
Valla, J.1
Schneider, L.2
Niedzielko, T.3
Coon, K.D.4
Caselli, R.5
Sabbagh, M.N.6
Ahern, G.L.7
Baxter, L.8
Alexander, G.9
Walker, D.G.10
-
3
-
-
79958226299
-
Clinical practice. Mild cognitive impairment
-
Petersen, R.C. (2011) Clinical practice. Mild cognitive impairment. N. Engl. J. Med., 364, 2227-2234.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2227-2234
-
-
Petersen, R.C.1
-
5
-
-
77956224679
-
The Alzheimer's disease mitochondrial cascade hypothesis
-
Swerdlow, R.H., Burns, J.M. and Khan, S.M. (2010) The Alzheimer's disease mitochondrial cascade hypothesis. J. Alzheimers Dis., 20, S265-S279.
-
(2010)
J. Alzheimers Dis.
, vol.20
-
-
Swerdlow, R.H.1
Burns, J.M.2
Khan, S.M.3
-
6
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai, K., Aliev, G., Nunomura, A., Fujioka, H., Russell, R.L., Atwood, C.S., Johnson, A.B., Kress, Y., Vinters, H.V., Tabaton, M. et al. (2001) Mitochondrial abnormalities in Alzheimer's disease. J. Neurosci., 21, 3017-3023.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
-
7
-
-
38349046973
-
Autophagy, amyloidogenesis and Alzheimer disease
-
Nixon, R.A. (2007) Autophagy, amyloidogenesis and Alzheimer disease. J. Cell Sci., 120, 4081-4091.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 4081-4091
-
-
Nixon, R.A.1
-
8
-
-
77950632324
-
Abeta promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons
-
Henriques, A.G., Vieira, S.I., da Cruz, E.S.E.F. and da Cruz, E.S.O.A. (2010) Abeta promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons. J. Neurochem., 113, 761-771.
-
(2010)
J. Neurochem.
, vol.113
, pp. 761-771
-
-
Henriques, A.G.1
Vieira, S.I.2
Da Cruz, E.S.E.F.3
Da Cruz, E.S.O.A.4
-
9
-
-
80053559887
-
Amyloid-beta-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway
-
Silva, D.F., Esteves, A.R., Arduino, D.M., Oliveira, C.R. and Cardoso, S.M. (2011) Amyloid-beta-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway. J. Alzheimers Dis., 26, 565-581.
-
(2011)
J. Alzheimers Dis.
, vol.26
, pp. 565-581
-
-
Silva, D.F.1
Esteves, A.R.2
Arduino, D.M.3
Oliveira, C.R.4
Cardoso, S.M.5
-
10
-
-
0033903441
-
Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease
-
de la Monte, S.M., Luong, T., Neely, T.R., Robinson, D. and Wands, J.R. (2000) Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease. Lab Invest., 80, 1323-1335.
-
(2000)
Lab Invest.
, vol.80
, pp. 1323-1335
-
-
De La Monte, S.M.1
Luong, T.2
Neely, T.R.3
Robinson, D.4
Wands, J.R.5
-
11
-
-
0032973069
-
Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology
-
Nagy, Z., Esiri, M.M., LeGris,M. and Matthews, P.M. (1999) Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology. Acta Neuropathol., 97, 346-354.
-
(1999)
Acta Neuropathol.
, vol.97
, pp. 346-354
-
-
Nagy, Z.1
Esiri, M.M.2
LeGris, M.3
Matthews, P.M.4
-
12
-
-
77955090213
-
Abnormal mitochondrial dynamics-a novel therapeutic target for Alzheimer's disease?
-
Su, B., Wang, X., Bonda, D., Perry, G., Smith, M. and Zhu, X. (2010) Abnormal mitochondrial dynamics-a novel therapeutic target for Alzheimer's disease? Mol. Neurobiol., 41, 87-96.
-
(2010)
Mol. Neurobiol.
, vol.41
, pp. 87-96
-
-
Su, B.1
Wang, X.2
Bonda, D.3
Perry, G.4
Smith, M.5
Zhu, X.6
-
13
-
-
77956199031
-
Asynergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease
-
Santos, R.X., Correia, S.C., Wang, X., Perry, G., Smith, M.A., Moreira, P.I. and Zhu, X. (2010)Asynergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. J. Alzheimers Dis., 20, S401-S412.
-
(2010)
J. Alzheimers Dis.
, vol.20
-
-
Santos, R.X.1
Correia, S.C.2
Wang, X.3
Perry, G.4
Smith, M.A.5
Moreira, P.I.6
Zhu, X.7
-
14
-
-
34250204271
-
The machines that divide and fuse mitochondria
-
Hoppins, S., Lackner, L. and Nunnari, J. (2007) The machines that divide and fuse mitochondria. Annu. Rev. Biochem., 76, 751-780.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 751-780
-
-
Hoppins, S.1
Lackner, L.2
Nunnari, J.3
-
15
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
Wang, X., Su, B., Lee, H.G., Li, X., Perry, G., Smith, M.A. and Zhu, X. (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J. Neurosci., 29, 9090-9103.
-
(2009)
J. Neurosci.
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
Perry, G.5
Smith, M.A.6
Zhu, X.7
-
16
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
-
Manczak, M., Calkins, M.J. and Reddy, P.H. (2011) Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Hum. Mol. Genet., 20, 2495-2509.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
17
-
-
58049218922
-
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
Wang, X., Su, B., Siedlak, S.L., Moreira, P.I., Fujioka, H., Wang, Y., Casadesus, G. and Zhu, X. (2008) Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc. Natl Acad. Sci. USA, 105, 19318-19323.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
Casadesus, G.7
Zhu, X.8
-
18
-
-
79954571354
-
The interplay between mitochondrial dynamics and mitophagy
-
Twig, G. and Shirihai, O.S. (2011) The interplay between mitochondrial dynamics and mitophagy. Antioxid. Redox Signal., 14, 1939-1951.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 1939-1951
-
-
Twig, G.1
Shirihai, O.S.2
-
19
-
-
84875000768
-
Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimers disease
-
Silva, D.F., Santana, I., Esteves, A.R., Baldeiras, I., Arduino, D.M., Oliveira, C.R. and Cardoso, S.M. (2012) Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimers disease. Curr. Alzheimer Res., 10, 180-190.
-
(2012)
Curr. Alzheimer Res.
, vol.10
, pp. 180-190
-
-
Silva, D.F.1
Santana, I.2
Esteves, A.R.3
Baldeiras, I.4
Arduino, D.M.5
Oliveira, C.R.6
Cardoso, S.M.7
-
20
-
-
1642578313
-
Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture
-
Trimmer, P.A., Keeney, P.M., Borland, M.K., Simon, F.A., Almeida, J., Swerdlow, R.H., Parks, J.P., Parker, W.D. Jr and Bennett, J.P. Jr. (2004) Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture. Neurobiol. Dis., 15, 29-39.
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 29-39
-
-
Trimmer, P.A.1
Keeney, P.M.2
Borland, M.K.3
Simon, F.A.4
Almeida, J.5
Swerdlow, R.H.6
Parks, J.P.7
Parker Jr., W.D.8
Bennett Jr., J.P.9
-
21
-
-
3042513691
-
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity
-
Cardoso, S.M., Santana, I., Swerdlow, R.H. and Oliveira, C.R. (2004) Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity. J. Neurochem., 89, 1417-1426.
-
(2004)
J. Neurochem.
, vol.89
, pp. 1417-1426
-
-
Cardoso, S.M.1
Santana, I.2
Swerdlow, R.H.3
Oliveira, C.R.4
-
22
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza, G.L. (2012) Hypoxia-inducible factors in physiology and medicine. Cell, 148, 399-408.
-
(2012)
Cell
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
23
-
-
33845596500
-
Peroxisome proliferatoractivated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
-
Handschin, C. and Spiegelman, B.M. (2006) Peroxisome proliferatoractivated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr. Rev., 27, 728-735.
-
(2006)
Endocr. Rev.
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
24
-
-
79952303794
-
PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease
-
Shin, J.H., Ko, H.S., Kang, H., Lee, Y., Lee, Y.I., Pletinkova, O., Troconso, J.C., Dawson, V.L. and Dawson, T.M. (2011) PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease. Cell, 144, 689-702.
-
(2011)
Cell
, vol.144
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
Troconso, J.C.7
Dawson, V.L.8
Dawson, T.M.9
-
25
-
-
64549127790
-
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Canto, C. and Auwerx, J. (2009) PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr. Opin. Lipidol., 20, 98-105.
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
26
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
-
Nemoto, S., Fergusson, M.M. and Finkel, T. (2005) SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J. Biol. Chem., 280, 16456-16460.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
27
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jager, S., Handschin, C., St-Pierre, J. and Spiegelman, B.M. (2007) AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl Acad. Sci. USA, 104, 12017-12022.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 12017-12022
-
-
Jager, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
28
-
-
34249727164
-
Transcriptional coregulators in the control of energy homeostasis
-
Feige, J.N. and Auwerx, J. (2007) Transcriptional coregulators in the control of energy homeostasis. Trends Cell Biol., 17, 292-301.
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 292-301
-
-
Feige, J.N.1
Auwerx, J.2
-
29
-
-
77956309945
-
Nerve growth factor attenuates oxidant-induced beta-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids
-
Onyango, I.G., Ahn, J.Y., Tuttle, J.B., Bennett, J.P. Jr and Swerdlow, R.H. (2010) Nerve growth factor attenuates oxidant-induced beta-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids. J. Neurochem., 114, 1605-1618.
-
(2010)
J. Neurochem.
, vol.114
, pp. 1605-1618
-
-
Onyango, I.G.1
Ahn, J.Y.2
Tuttle, J.B.3
Bennett Jr., J.P.4
Swerdlow, R.H.5
-
30
-
-
19444381217
-
Altered intracellular signaling and reduced viability of Alzheimer's disease neuronal cybrids is reproduced by beta-amyloid peptide acting through receptor for advanced glycation end products (RAGE)
-
Onyango, I.G., Tuttle, J.B. and Bennett, J.P. Jr. (2005) Altered intracellular signaling and reduced viability of Alzheimer's disease neuronal cybrids is reproduced by beta-amyloid peptide acting through receptor for advanced glycation end products (RAGE). Mol. Cell Neurosci., 29, 333-343.
-
(2005)
Mol. Cell Neurosci.
, vol.29
, pp. 333-343
-
-
Onyango, I.G.1
Tuttle, J.B.2
Bennett Jr., J.P.3
-
31
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
Scarpulla, R.C. (2008) Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev., 88, 611-638.
-
(2008)
Physiol. Rev.
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
32
-
-
33750445482
-
Mitochondrial fusion and fission in mammals
-
Chan, D.C. (2006) Mitochondrial fusion and fission in mammals. Annu. Rev. Cell Dev. Biol., 22, 79-99.
-
(2006)
Annu. Rev. Cell Dev. Biol.
, vol.22
, pp. 79-99
-
-
Chan, D.C.1
-
33
-
-
77951096150
-
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
-
Chen, H. and Chan, D.C. (2009) Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases. Hum. Mol. Genet., 18, R169-R176.
-
(2009)
Hum. Mol. Genet.
, vol.18
-
-
Chen, H.1
Chan, D.C.2
-
34
-
-
57349160257
-
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
-
Cereghetti, G.M., Stangherlin, A., Martins de Brito, O., Chang, C.R., Blackstone, C., Bernardi, P. and Scorrano, L. (2008) Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria. Proc. Natl Acad. Sci. USA, 105, 15803-15808.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 15803-15808
-
-
Cereghetti, G.M.1
Stangherlin, A.2
Martins De Brito, O.3
Chang, C.R.4
Blackstone, C.5
Bernardi, P.6
Scorrano, L.7
-
35
-
-
77957851365
-
Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin
-
Cereghetti, G.M., Costa, V. and Scorrano, L. (2010) Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin. Cell Death Differ., 17, 1785-1794.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1785-1794
-
-
Cereghetti, G.M.1
Costa, V.2
Scorrano, L.3
-
36
-
-
77953854247
-
Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis
-
Cho, S.G., Du, Q., Huang, S. and Dong, Z. (2010) Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis. Am. J. Physiol. Renal Physiol., 299, F199-F206.
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Cho, S.G.1
Du, Q.2
Huang, S.3
Dong, Z.4
-
37
-
-
77951919835
-
Bcl-2 family proteins and mitochondrial fission/fusion dynamics
-
Autret, A. and Martin, S.J. (2010) Bcl-2 family proteins and mitochondrial fission/fusion dynamics. Cell Mol. Life Sci., 67, 1599-1606.
-
(2010)
Cell Mol. Life Sci.
, vol.67
, pp. 1599-1606
-
-
Autret, A.1
Martin, S.J.2
-
38
-
-
49349105966
-
Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release
-
Sheridan, C., Delivani, P., Cullen, S.P. and Martin, S.J. (2008) Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release. Mol. Cell, 31, 570-585.
-
(2008)
Mol. Cell
, vol.31
, pp. 570-585
-
-
Sheridan, C.1
Delivani, P.2
Cullen, S.P.3
Martin, S.J.4
-
39
-
-
36749081539
-
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
-
Cunningham, J.T., Rodgers, J.T., Arlow, D.H., Vazquez, F., Mootha, V.K. and Puigserver, P. (2007) mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature, 450, 736-740.
-
(2007)
Nature
, vol.450
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
Puigserver, P.6
-
40
-
-
33748752151
-
The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
-
Schieke, S.M., Phillips, D., McCoy, J.P. Jr, Aponte, A.M., Shen, R.F., Balaban, R.S. and Finkel, T. (2006) The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J. Biol. Chem., 281, 27643-27652.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27643-27652
-
-
Schieke, S.M.1
Phillips, D.2
McCoy Jr., J.P.3
Aponte, A.M.4
Shen, R.F.5
Balaban, R.S.6
Finkel, T.7
-
41
-
-
84867901268
-
The neuropathological profile of mild cognitive impairment (MCI): a systematic review
-
Stephan, B.C., Hunter, S., Harris, D., Llewellyn, D.J., Siervo, M., Matthews, F.E. and Brayne, C. (2012) The neuropathological profile of mild cognitive impairment (MCI): a systematic review. Mol. Psychiatry, 17, 1056-1076.
-
(2012)
Mol. Psychiatry
, vol.17
, pp. 1056-1076
-
-
Stephan, B.C.1
Hunter, S.2
Harris, D.3
Llewellyn, D.J.4
Siervo, M.5
Matthews, F.E.6
Brayne, C.7
-
42
-
-
0025024024
-
Cytochrome oxidase deficiency in Alzheimer's disease
-
Parker, W.D. Jr, Filley, C.M. and Parks, J.K. (1990) Cytochrome oxidase deficiency in Alzheimer's disease. Neurology, 40, 1302-1303.
-
(1990)
Neurology
, vol.40
, pp. 1302-1303
-
-
Parker Jr., W.D.1
Filley, C.M.2
Parks, J.K.3
-
43
-
-
0030724118
-
Cybrids in Alzheimer's disease: a cellular model of the disease?
-
Swerdlow, R.H., Parks, J.K., Cassarino, D.S., Maguire, D.J., Maguire, R.S., Bennett, J.P. Jr, Davis, R.E. and Parker, W.D. Jr. (1997) Cybrids in Alzheimer's disease: a cellular model of the disease? Neurology, 49, 918-925.
-
(1997)
Neurology
, vol.49
, pp. 918-925
-
-
Swerdlow, R.H.1
Parks, J.K.2
Cassarino, D.S.3
Maguire, D.J.4
Maguire, R.S.5
Bennett Jr., J.P.6
Davis, R.E.7
Parker Jr., W.D.8
-
44
-
-
0038644221
-
The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide
-
Soucek, T., Cumming, R., Dargusch, R., Maher, P. and Schubert, D. (2003) The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide. Neuron, 39, 43-56.
-
(2003)
Neuron
, vol.39
, pp. 43-56
-
-
Soucek, T.1
Cumming, R.2
Dargusch, R.3
Maher, P.4
Schubert, D.5
-
45
-
-
0035824167
-
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome
-
Silverman, D.H., Small, G.W., Chang, C.Y., Lu, C.S., Kung De Aburto, M.A., Chen, W., Czernin, J., Rapoport, S.I., Pietrini, P., Alexander, G.E. et al. (2001) Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. JAMA, 286, 2120-2127.
-
(2001)
JAMA
, vol.286
, pp. 2120-2127
-
-
Silverman, D.H.1
Small, G.W.2
Chang, C.Y.3
Lu, C.S.4
Kung Aburto, M.A.5
Chen, W.6
Czernin, J.7
Rapoport, S.I.8
Pietrini, P.9
Alexander, G.E.10
-
46
-
-
35748930217
-
The role of neuroimaging in mild cognitive impairment
-
Matsuda, H. (2007) The role of neuroimaging in mild cognitive impairment. Neuropathology, 27, 570-577.
-
(2007)
Neuropathology
, vol.27
, pp. 570-577
-
-
Matsuda, H.1
-
47
-
-
0033233243
-
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
-
Semenza, G.L. (1999) Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol., 15, 551-578.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
48
-
-
38049050725
-
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
-
Liu, Y., Liu, F., Iqbal, K., Grundke-Iqbal, I. and Gong, C.X. (2008) Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease. FEBS Lett., 582, 359-364.
-
(2008)
FEBS Lett.
, vol.582
, pp. 359-364
-
-
Liu, Y.1
Liu, F.2
Iqbal, K.3
Grundke-Iqbal, I.4
Gong, C.X.5
-
49
-
-
33646014454
-
Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: implications for disease pathogenesis
-
Grammas, P., Samany, P.G. and Thirumangalakudi, L. (2006) Thrombin and inflammatory proteins are elevated in Alzheimer's disease microvessels: implications for disease pathogenesis. J. Alzheimers Dis., 9, 51-58.
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 51-58
-
-
Grammas, P.1
Samany, P.G.2
Thirumangalakudi, L.3
-
50
-
-
62449166389
-
PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia
-
Qin, W., Haroutunian, V., Katsel, P., Cardozo, C.P., Ho, L., Buxbaum, J.D. and Pasinetti, G.M. (2009) PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Arch. Neurol., 66, 352-361.
-
(2009)
Arch. Neurol.
, vol.66
, pp. 352-361
-
-
Qin, W.1
Haroutunian, V.2
Katsel, P.3
Cardozo, C.P.4
Ho, L.5
Buxbaum, J.D.6
Pasinetti, G.M.7
-
51
-
-
84855687153
-
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease
-
Sheng, B., Wang, X., Su, B., Lee, H.G., Casadesus, G., Perry, G. and Zhu, X. (2012) Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J. Neurochem., 120, 419-429.
-
(2012)
J. Neurochem.
, vol.120
, pp. 419-429
-
-
Sheng, B.1
Wang, X.2
Su, B.3
Lee, H.G.4
Casadesus, G.5
Perry, G.6
Zhu, X.7
-
52
-
-
33749630419
-
PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth
-
Vercauteren, K., Pasko, R.A., Gleyzer, N., Marino, V.M. and Scarpulla, R.C. (2006) PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth. Mol. Cell Biol., 26, 7409-7419.
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 7409-7419
-
-
Vercauteren, K.1
Pasko, R.A.2
Gleyzer, N.3
Marino, V.M.4
Scarpulla, R.C.5
-
53
-
-
84855686219
-
beta-Apptists and Tauists, it is time for a sermon from the book of biogenesis
-
Swerdlow, R.H. (2012) beta-Apptists and Tauists, it is time for a sermon from the book of biogenesis. J. Neurochem., 120, 347-349.
-
(2012)
J. Neurochem.
, vol.120
, pp. 347-349
-
-
Swerdlow, R.H.1
-
54
-
-
34548471739
-
Cytoplasm-localized SIRT1 enhances apoptosis
-
Jin, Q., Yan, T., Ge, X., Sun, C., Shi, X. and Zhai, Q. (2007) Cytoplasm-localized SIRT1 enhances apoptosis. J. Cell Physiol., 213, 88-97.
-
(2007)
J. Cell Physiol.
, vol.213
, pp. 88-97
-
-
Jin, Q.1
Yan, T.2
Ge, X.3
Sun, C.4
Shi, X.5
Zhai, Q.6
-
55
-
-
84868560653
-
Redox regulation of mitochondrial biogenesis
-
Piantadosi, C.A. and Suliman, H.B. (2012) Redox regulation of mitochondrial biogenesis. Free Radic. Biol. Med., 53, 2043-2053.
-
(2012)
Free Radic. Biol. Med.
, vol.53
, pp. 2043-2053
-
-
Piantadosi, C.A.1
Suliman, H.B.2
-
56
-
-
0033043939
-
p38 kinase is activated in the Alzheimer's disease brain
-
Hensley, K., Floyd, R.A., Zheng, N.Y., Nael, R., Robinson, K.A., Nguyen, X., Pye, Q.N., Stewart, C.A., Geddes, J., Markesbery, W.R. et al. (1999) p38 kinase is activated in the Alzheimer's disease brain. J. Neurochem., 72, 2053-2058.
-
(1999)
J. Neurochem.
, vol.72
, pp. 2053-2058
-
-
Hensley, K.1
Floyd, R.A.2
Zheng, N.Y.3
Nael, R.4
Robinson, K.A.5
Nguyen, X.6
Pye, Q.N.7
Stewart, C.A.8
Geddes, J.9
Markesbery, W.R.10
-
57
-
-
0141672049
-
P38 MAP kinase is activated at early stages in Alzheimer's disease brain
-
Sun, A., Liu, M., Nguyen, X.V. and Bing, G. (2003) P38 MAP kinase is activated at early stages in Alzheimer's disease brain. Exp. Neurol., 183, 394-405.
-
(2003)
Exp. Neurol.
, vol.183
, pp. 394-405
-
-
Sun, A.1
Liu, M.2
Nguyen, X.V.3
Bing, G.4
-
58
-
-
79952135316
-
AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies
-
Vingtdeux, V., Davies, P., Dickson,D.W. and Marambaud, P. (2011)AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies. Acta Neuropath., 121, 337-349.
-
(2011)
Acta Neuropath.
, vol.121
, pp. 337-349
-
-
Vingtdeux, V.1
Davies, P.2
Dickson, D.W.3
Marambaud, P.4
-
59
-
-
64049092736
-
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease
-
Julien, C., Tremblay, C., Emond, V., Lebbadi, M., Salem, N. Jr, Bennett, D.A. and Calon, F. (2009) Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease. J. Neuropathol. Exp. Neurol., 68, 48-58.
-
(2009)
J. Neuropathol. Exp. Neurol.
, vol.68
, pp. 48-58
-
-
Julien, C.1
Tremblay, C.2
Emond, V.3
Lebbadi, M.4
Salem Jr., N.5
Bennett, D.A.6
Calon, F.7
-
60
-
-
79960566233
-
AMP-activated protein kinase: a potential player in Alzheimer's disease
-
Salminen, A., Kaarniranta, K., Haapasalo, A., Soininen, H. and Hiltunen, M. (2011) AMP-activated protein kinase: a potential player in Alzheimer's disease. J. Neurochem., 118, 460-474.
-
(2011)
J. Neurochem.
, vol.118
, pp. 460-474
-
-
Salminen, A.1
Kaarniranta, K.2
Haapasalo, A.3
Soininen, H.4
Hiltunen, M.5
-
61
-
-
77953577017
-
mTOR'srole in ageing: protein synthesis or autophagy?
-
Hands, S.L., Proud, C.G. and Wyttenbach, A. (2009)mTOR'srole in ageing: protein synthesis or autophagy? Aging, 1, 586-597.
-
(2009)
Aging
, vol.1
, pp. 586-597
-
-
Hands, S.L.1
Proud, C.G.2
Wyttenbach, A.3
-
62
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
Ravikumar, B., Vacher, C., Berger, Z., Davies, J.E., Luo, S., Oroz, L.G., Scaravilli, F., Easton, D.F., Duden, R., O'Kane, C.J. et al. (2004) Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat. Genet., 36, 585-595.
-
(2004)
Nat. Genet.
, vol.36
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
-
63
-
-
23844457609
-
Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain
-
Li, X., Alafuzoff, I., Soininen, H., Winblad, B. and Pei, J.J. (2005) Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain. FEBS J., 272, 4211-4220.
-
(2005)
FEBS J.
, vol.272
, pp. 4211-4220
-
-
Li, X.1
Alafuzoff, I.2
Soininen, H.3
Winblad, B.4
Pei, J.J.5
-
64
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
-
Boland, B., Kumar, A., Lee, S., Platt, F.M., Wegiel, J., Yu, W.H. and Nixon, R.A. (2008) Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci., 28, 6926-6937.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
65
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study
-
Nixon, R.A., Wegiel, J., Kumar, A., Yu, W.H., Peterhoff, C., Cataldo, A. and Cuervo, A.M. (2005) Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J. Neuropathol. Exp. Neurol., 64, 113-122.
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
66
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima, N., Levine, B., Cuervo, A.M. and Klionsky, D.J. (2008) Autophagy fights disease through cellular self-digestion. Nature, 451, 1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
67
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig, G., Elorza, A., Molina, A.J., Mohamed, H., Wikstrom, J.D., Walzer, G., Stiles, L., Haigh, S.E., Katz, S., Las, G. et al. (2008) Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J., 27, 433-446.
-
(2008)
EMBO J.
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
-
68
-
-
0035042470
-
Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA)
-
Brown, A.M., Sheu, R.K., Mohs, R., Haroutunian, V. and Blass, J.P. (2001) Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA). J. Mol. Neurosci., 16, 41-48.
-
(2001)
J. Mol. Neurosci.
, vol.16
, pp. 41-48
-
-
Brown, A.M.1
Sheu, R.K.2
Mohs, R.3
Haroutunian, V.4
Blass, J.P.5
-
69
-
-
3242668604
-
Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
-
Coskun, P.E., Beal, M.F. and Wallace, D.C. (2004) Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proc. Natl Acad. Sci. USA, 101, 10726-10731.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10726-10731
-
-
Coskun, P.E.1
Beal, M.F.2
Wallace, D.C.3
-
70
-
-
0035058647
-
Is mitochondrial DNA depletion involved in Alzheimer's disease?
-
Rodriguez-Santiago, B., Casademont, J. and Nunes, V. (2001) Is mitochondrial DNA depletion involved in Alzheimer's disease? Eur. J. Hum. Genet., 9, 279-285.
-
(2001)
Eur. J. Hum. Genet.
, vol.9
, pp. 279-285
-
-
Rodriguez-Santiago, B.1
Casademont, J.2
Nunes, V.3
-
71
-
-
33746256557
-
Mitochondrial alterations in Alzheimer's disease
-
Baloyannis, S.J. (2006) Mitochondrial alterations in Alzheimer's disease. J. Alzheimers Dis., 9, 119-126.
-
(2006)
J. Alzheimers Dis.
, vol.9
, pp. 119-126
-
-
Baloyannis, S.J.1
-
72
-
-
81555195711
-
Mitochondria are related to synaptic pathology in Alzheimer's disease
-
Baloyannis, S.J. (2011) Mitochondria are related to synaptic pathology in Alzheimer's disease. Int. J. Alzheimers Dis., 2011, 305395.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 305395
-
-
Baloyannis, S.J.1
-
73
-
-
2342628596
-
Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage
-
Manczak, M., Park, B.S., Jung, Y. and Reddy, P.H. (2004) Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage. Neuromolecular Med., 5, 147-162.
-
(2004)
Neuromolecular Med.
, vol.5
, pp. 147-162
-
-
Manczak, M.1
Park, B.S.2
Jung, Y.3
Reddy, P.H.4
-
74
-
-
0035099984
-
Mild cognitive impairment represents early-stage Alzheimer disease
-
Morris, J.C., Storandt, M., Miller, J.P., McKeel, D.W., Price, J.L., Rubin, E.H. and Berg, L. (2001) Mild cognitive impairment represents early-stage Alzheimer disease. Arch. Neurol., 58, 397-405.
-
(2001)
Arch. Neurol.
, vol.58
, pp. 397-405
-
-
Morris, J.C.1
Storandt, M.2
Miller, J.P.3
McKeel, D.W.4
Price, J.L.5
Rubin, E.H.6
Berg, L.7
-
75
-
-
67649687124
-
The Alzheimer's disease mitochondrial cascade hypothesis: an update
-
Swerdlow, R.H. and Khan, S.M. (2009) The Alzheimer's disease mitochondrial cascade hypothesis: an update. Exp. Neurol., 218, 308-315.
-
(2009)
Exp. Neurol.
, vol.218
, pp. 308-315
-
-
Swerdlow, R.H.1
Khan, S.M.2
-
76
-
-
3042806534
-
A 'mitochondrial cascade hypothesis' for sporadic Alzheimer's disease
-
Swerdlow, R.H. and Khan, S.M. (2004) A 'mitochondrial cascade hypothesis' for sporadic Alzheimer's disease. Med. Hypotheses, 63, 8-20.
-
(2004)
Med. Hypotheses
, vol.63
, pp. 8-20
-
-
Swerdlow, R.H.1
Khan, S.M.2
-
77
-
-
34347353834
-
Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies
-
Swerdlow, R.H. (2007) Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies. J. Neurosci. Res., 85, 3416-3428.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 3416-3428
-
-
Swerdlow, R.H.1
-
78
-
-
77954963850
-
Polymorphic variation in cytochrome oxidase subunit genes
-
Lu, J., Wang, K., Rodova, M., Esteves, R., Berry, D., E, L., Crafter, A., Barrett, M., Cardoso, S.M., Onyango, I. et al. (2010) Polymorphic variation in cytochrome oxidase subunit genes. J. Alzheimers Dis., 21, 141-154.
-
(2010)
J. Alzheimers Dis.
, vol.21
, pp. 141-154
-
-
Lu, J.1
Wang, K.2
Rodova, M.3
Esteves, R.4
Berry, D.E.L.5
Crafter, A.6
Barrett, M.7
Cardoso, S.M.8
Onyango, I.9
-
79
-
-
80055078025
-
Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases
-
Swerdlow, R.H. (2011) Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases. Curr. Pharm. Des., 17, 3356-3373.
-
(2011)
Curr. Pharm. Des.
, vol.17
, pp. 3356-3373
-
-
Swerdlow, R.H.1
-
80
-
-
0029800941
-
Creation and characterization of mitochondrial DNA-depleted cell lines with ?neuronal-like' properties
-
Miller, S.W., Trimmer, P.A., Parker, W.D. Jr and Davis, R.E. (1996) Creation and characterization of mitochondrial DNA-depleted cell lines with ?neuronal-like' properties. J. Neurochem., 67, 1897-1907.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1897-1907
-
-
Miller, S.W.1
Trimmer, P.A.2
Parker Jr., W.D.3
Davis, R.E.4
-
81
-
-
0029908226
-
Origin and functional consequences of the complex I defect in Parkinson's disease
-
Swerdlow, R.H., Parks, J.K., Miller, S.W., Tuttle, J.B., Trimmer, P.A., Sheehan, J.P., Bennett, J.P. Jr, Davis, R.E. and Parker,W.D.Jr. (1996) Origin and functional consequences of the complex I defect in Parkinson's disease. Ann. Neurol., 40, 663-671.
-
(1996)
Ann. Neurol.
, vol.40
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett Jr., J.P.7
Davis, R.E.8
Parker Jr., W.D.9
|