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Volumn 95, Issue 3, 1998, Pages 343-353

CNK, a RAF-binding multidomain protein required for RAS signaling

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; RAF PROTEIN; RAS PROTEIN;

EID: 0032582663     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81766-3     Document Type: Article
Times cited : (146)

References (52)
  • 1
    • 0028915798 scopus 로고
    • Prolinerich sequences that bind to Src homology 3 domains with individual specificities
    • Alexandropoulos, K., Cheng, G., and Baltimore, D. (1995). Prolinerich sequences that bind to Src homology 3 domains with individual specificities. Proc. Natl. Acad. Sci. USA 92, 3110-3114.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3110-3114
    • Alexandropoulos, K.1    Cheng, G.2    Baltimore, D.3
  • 2
    • 0025973804 scopus 로고
    • Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye
    • Basler, K., Christen, B., and Hafen, E. (1991). Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell 64, 1069-1081.
    • (1991) Cell , vol.64 , pp. 1069-1081
    • Basler, K.1    Christen, B.2    Hafen, E.3
  • 3
    • 0028328631 scopus 로고
    • Again-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways
    • Brunner, D., Oellers, N., Szabad, J., Biggs, W.H., III, Zipursky, S.L., and Hafen, E. (1994). Again-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell 76, 875-888.
    • (1994) Cell , vol.76 , pp. 875-888
    • Brunner, D.1    Oellers, N.2    Szabad, J.3    Biggs W.H. III4    Zipursky, S.L.5    Hafen, E.6
  • 5
    • 0028343745 scopus 로고
    • The sevenless signaling cassette mediates Drosophila EGF receptor function during epidermal development
    • Diaz-Benjumea, F.J., and Hafen, E. (1994). The sevenless signaling cassette mediates Drosophila EGF receptor function during epidermal development. Development 120, 569-578.
    • (1994) Development , vol.120 , pp. 569-578
    • Diaz-Benjumea, F.J.1    Hafen, E.2
  • 6
    • 0026679892 scopus 로고
    • Raf functions downstream of Ras1 in the Sevenless signal transduction pathway
    • Dickson, B., Sprenger, F., Morrison, D., and Hafen, E. (1992). Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360, 600-603.
    • (1992) Nature , vol.360 , pp. 600-603
    • Dickson, B.1    Sprenger, F.2    Morrison, D.3    Hafen, E.4
  • 7
    • 0026575220 scopus 로고
    • Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation
    • Fortini, M.E., Simon, M.A., and Rubin, G.M. (1992). Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature 355, 559-561.
    • (1992) Nature , vol.355 , pp. 559-561
    • Fortini, M.E.1    Simon, M.A.2    Rubin, G.M.3
  • 8
    • 0002337352 scopus 로고
    • Two-hybrid systems/interaction traps
    • F.M. Ausubel, R. Brent, R. Kingston, D. Moore, J. Seidman, J.A. Smith, and K. Struhl, eds. (New York: John Wiley and Sons)
    • Golemis, E., Gyuris, J., and Brent, R. (1994). Two-hybrid systems/interaction traps. In Current Protocol in Molecular Biology, F.M. Ausubel, R. Brent, R. Kingston, D. Moore, J. Seidman, J.A. Smith, and K. Struhl, eds. (New York: John Wiley and Sons), pp. 13.14.1-13.14.17.
    • (1994) Current Protocol in Molecular Biology , pp. 13141-131417
    • Golemis, E.1    Gyuris, J.2    Brent, R.3
  • 9
    • 0027428530 scopus 로고
    • RAF-1 forms a stable complex with MEK1 and activates MEK1 by serine phosphorylation
    • Huang, W., Alessandrini, A., Crews, C.M., and Erikson, R.L. (1993). RAF-1 forms a stable complex with MEK1 and activates MEK1 by serine phosphorylation. Proc. Natl. Acad. Sci. USA 90, 10947-10951.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10947-10951
    • Huang, W.1    Alessandrini, A.2    Crews, C.M.3    Erikson, R.L.4
  • 11
    • 0029869355 scopus 로고    scopus 로고
    • A screen for genes that function downstream of Ras1 during Drosophila eye development
    • Karim, F.D., Chang, H.C., Therrien, M., Wassarman, D.A., Laverty, T., and Rubin, G.M. (1996). A screen for genes that function downstream of Ras1 during Drosophila eye development. Genetics 143, 315-329.
    • (1996) Genetics , vol.143 , pp. 315-329
    • Karim, F.D.1    Chang, H.C.2    Therrien, M.3    Wassarman, D.A.4    Laverty, T.5    Rubin, G.M.6
  • 12
    • 0030720016 scopus 로고    scopus 로고
    • Polarized signaling: Basolateral receptor localization in epithelial cells by PDZ-containing proteins
    • Kim, S.K. (1997). Polarized signaling: basolateral receptor localization in epithelial cells by PDZ-containing proteins. Curr. Opin. Cell Biol. 9, 853-859.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 853-859
    • Kim, S.K.1
  • 13
    • 0025276935 scopus 로고
    • The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype
    • Kimmel, B.E., Heberlein, U., and Rubin, G.M. (1990). The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 4, 712-727.
    • (1990) Genes Dev. , vol.4 , pp. 712-727
    • Kimmel, B.E.1    Heberlein, U.2    Rubin, G.M.3
  • 14
    • 0028913319 scopus 로고
    • Not just glue: Cell-cell junctions as cellular signaling centers
    • Kirkpatrick, C., and Peifer, M. (1995). Not just glue: cell-cell junctions as cellular signaling centers. Curr. Opin. Genet. Dev. 5, 56-65.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 56-65
    • Kirkpatrick, C.1    Peifer, M.2
  • 15
    • 0029588204 scopus 로고
    • The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
    • Kornfeld, K., Hom, D.B., and Horvitz, H.R. (1995). The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell 83, 903-913.
    • (1995) Cell , vol.83 , pp. 903-913
    • Kornfeld, K.1    Hom, D.B.2    Horvitz, H.R.3
  • 16
    • 0031006326 scopus 로고    scopus 로고
    • Regulatory recruitment of signaling molecules to the cell membrane by pleckstrin-homology domains
    • Lemmon, M.A., Falasca, M., Ferguson, K.M., and Schlessinger, J. (1997). Regulatory recruitment of signaling molecules to the cell membrane by pleckstrin-homology domains. Trends Cell Biol. 7, 237-242.
    • (1997) Trends Cell Biol. , vol.7 , pp. 237-242
    • Lemmon, M.A.1    Falasca, M.2    Ferguson, K.M.3    Schlessinger, J.4
  • 17
    • 0028819903 scopus 로고
    • Integrins and the development of three-dimensional structure in the Drosophila compound eye
    • Longley, R.L., and Ready, D.F. (1995). Integrins and the development of three-dimensional structure in the Drosophila compound eye. Dev. Biol. 171, 415-433.
    • (1995) Dev. Biol. , vol.171 , pp. 415-433
    • Longley, R.L.1    Ready, D.F.2
  • 18
    • 0028292062 scopus 로고
    • Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction
    • Lu, X., Melnick, M.B., Hsu, J.C., and Perrimon, N. (1994). Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction. EMBO J. 13, 2592-2599.
    • (1994) EMBO J. , vol.13 , pp. 2592-2599
    • Lu, X.1    Melnick, M.B.2    Hsu, J.C.3    Perrimon, N.4
  • 19
    • 0027193783 scopus 로고
    • Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase
    • Melnick, M.B., Perkins, L.A., Lee, M., Ambrosio, L., and Perrimon, N. (1993). Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase. Development 118, 127-138.
    • (1993) Development , vol.118 , pp. 127-138
    • Melnick, M.B.1    Perkins, L.A.2    Lee, M.3    Ambrosio, L.4    Perrimon, N.5
  • 21
    • 0016613341 scopus 로고
    • Minutes: Mutants of Drosophila autonomously affecting cell division rate
    • Morata, G., and Ripoll, P. (1975). Minutes: mutants of Drosophila autonomously affecting cell division rate. Dev. Biol. 42, 211-221.
    • (1975) Dev. Biol. , vol.42 , pp. 211-221
    • Morata, G.1    Ripoll, P.2
  • 23
    • 0027183541 scopus 로고
    • The PH domain, a common piece in the structural patchwork of signaling proteins
    • Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. (1993). The PH domain, a common piece in the structural patchwork of signaling proteins. Trends Biochem. Sci. 18, 343-348.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 343-348
    • Musacchio, A.1    Gibson, T.2    Rice, P.3    Thompson, J.4    Saraste, M.5
  • 24
    • 0027468233 scopus 로고
    • A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos
    • Olivier, J.P., Raabe, T., Henkemeyer, M., Dickson, B., Mbamalu, G., Margolis, B., Schlessinger, J., Hafen, E., and Pawson, T. (1993). A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell 73, 179-191.
    • (1993) Cell , vol.73 , pp. 179-191
    • Olivier, J.P.1    Raabe, T.2    Henkemeyer, M.3    Dickson, B.4    Mbamalu, G.5    Margolis, B.6    Schlessinger, J.7    Hafen, E.8    Pawson, T.9
  • 25
    • 0031457622 scopus 로고    scopus 로고
    • Signaling through scaffold, anchoring, and adaptor proteins
    • Pawson, T., and Scott, J.D. (1997). Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-2080.
    • (1997) Science , vol.278 , pp. 2075-2080
    • Pawson, T.1    Scott, J.D.2
  • 26
    • 0031171361 scopus 로고    scopus 로고
    • PDZ domains: Targeting signaling molecules to sub-membranous sites
    • Ponting, C.P., Phillips, C., Davies, K.E., and Blake, D.J. (1997). PDZ domains: targeting signaling molecules to sub-membranous sites. Bioessays 19, 469-479.
    • (1997) Bioessays , vol.19 , pp. 469-479
    • Ponting, C.P.1    Phillips, C.2    Davies, K.E.3    Blake, D.J.4
  • 27
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans
    • Quiring, R., Walldorf, U., Kloter, U., and Gehring, W.J. (1994). Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265, 785-789.
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walldorf, U.2    Kloter, U.3    Gehring, W.J.4
  • 28
    • 0029984739 scopus 로고    scopus 로고
    • DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila
    • Raabe, T., Riesgo-Escovar, J., Liu, X., Bausenwein, B.S., Deak, P., Maröy, P., and Hafen, E. (1996). DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila. Cell 85, 911-920.
    • (1996) Cell , vol.85 , pp. 911-920
    • Raabe, T.1    Riesgo-Escovar, J.2    Liu, X.3    Bausenwein, B.S.4    Deak, P.5    Maröy, P.6    Hafen, E.7
  • 29
    • 0019945644 scopus 로고
    • Genetic transformation of Drosophila with transposable element vectors
    • Rubin, G.M., and Spradling, A.C. (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 30
    • 0031022602 scopus 로고    scopus 로고
    • SAM as a protein interaction domain involved in developmental regulation
    • Schultz, J., Ponting, C.P., Hofmann, K., and Bork, P. (1997). SAM as a protein interaction domain involved in developmental regulation. Protein Sci. 6, 249-253.
    • (1997) Protein Sci. , vol.6 , pp. 249-253
    • Schultz, J.1    Ponting, C.P.2    Hofmann, K.3    Bork, P.4
  • 31
    • 0031005779 scopus 로고    scopus 로고
    • A thousand and one roles for the Drosophila EGF receptor
    • Schweitzer, R., and Shilo, B.Z. (1997). A thousand and one roles for the Drosophila EGF receptor. Trends Genet. 13, 191-196.
    • (1997) Trends Genet. , vol.13 , pp. 191-196
    • Schweitzer, R.1    Shilo, B.Z.2
  • 32
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger, R., and Krebs, E.G. (1995). The MAPK signaling cascade. FASEB J. 9, 726-735.
    • (1995) FASEB J. , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 33
    • 0025997867 scopus 로고
    • Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
    • Simon, M.A., Bowtell, D.D.L., Dodson, G.S., Laverty, T.R., and Rubin, G.M. (1991). Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67, 701-716.
    • (1991) Cell , vol.67 , pp. 701-716
    • Simon, M.A.1    Bowtell, D.D.L.2    Dodson, G.S.3    Laverty, T.R.4    Rubin, G.M.5
  • 34
    • 0027404990 scopus 로고
    • An SH3-SH2-SH3 protein is required for p21 Ras1 activation and binds to sevenless and Sos proteins in vitro
    • Simon, M.A., Dodson, G.S., and Rubin, G.M. (1993). An SH3-SH2-SH3 protein is required for p21 Ras1 activation and binds to sevenless and Sos proteins in vitro. Cell 73, 169-177.
    • (1993) Cell , vol.73 , pp. 169-177
    • Simon, M.A.1    Dodson, G.S.2    Rubin, G.M.3
  • 37
    • 0028847033 scopus 로고
    • Gene disruption using P transposable elements: An integral component of the Drosophila genome project
    • Spradling, A.C., Stern, D.M., Kiss, I., Roote, J., Laverty, T., and Rubin, G.M. (1995). Gene disruption using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92, 10824-10830.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10824-10830
    • Spradling, A.C.1    Stern, D.M.2    Kiss, I.3    Roote, J.4    Laverty, T.5    Rubin, G.M.6
  • 38
    • 0028241533 scopus 로고
    • Activation of Raf as a result of recruitment to the plasma membrane
    • Stokoe, D., Macdonald, S.G., Cadwallader, K., Symons, M., and Hancock, J.F. (1994). Activation of Raf as a result of recruitment to the plasma membrane. Science 264, 1463-1467.
    • (1994) Science , vol.264 , pp. 1463-1467
    • Stokoe, D.1    Macdonald, S.G.2    Cadwallader, K.3    Symons, M.4    Hancock, J.F.5
  • 39
    • 0029559183 scopus 로고
    • The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction
    • Sundaram, M., and Han, M. (1995). The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83, 889-901.
    • (1995) Cell , vol.83 , pp. 889-901
    • Sundaram, M.1    Han, M.2
  • 40
    • 0029736912 scopus 로고    scopus 로고
    • Regulation of cell-cell contacts in developing Drosophila eyes by Dsrc41, a new, close relative of vertebrate c-src
    • Takahashi, F., Endo, S., Kojima, T., and Saigo, K. (1996). Regulation of cell-cell contacts in developing Drosophila eyes by Dsrc41, a new, close relative of vertebrate c-src. Genes Dev. 10, 1645-1656.
    • (1996) Genes Dev. , vol.10 , pp. 1645-1656
    • Takahashi, F.1    Endo, S.2    Kojima, T.3    Saigo, K.4
  • 41
    • 0026580006 scopus 로고
    • Brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2
    • Tamkun, J.W., Deuring, R., Scott, M.P., Kissinger, M., Pattatucci, A.M., Kaufman, T.C., and Kennison, J.A. (1992). brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68, 561-572.
    • (1992) Cell , vol.68 , pp. 561-572
    • Tamkun, J.W.1    Deuring, R.2    Scott, M.P.3    Kissinger, M.4    Pattatucci, A.M.5    Kaufman, T.C.6    Kennison, J.A.7
  • 43
    • 0029850713 scopus 로고    scopus 로고
    • KSR modulates signal propagation within the MAPK cascade
    • Therrien, M., Michaud, N.R., Rubin, G.M., and Morrison, D.K. (1996). KSR modulates signal propagation within the MAPK cascade. Genes Dev. 10, 2684-2695.
    • (1996) Genes Dev. , vol.10 , pp. 2684-2695
    • Therrien, M.1    Michaud, N.R.2    Rubin, G.M.3    Morrison, D.K.4
  • 44
    • 0023256656 scopus 로고
    • Neuronal differentiation in the Drosophila ommatidium
    • Tomlinson, A., and Ready, D.F. (1987). Neuronal differentiation in the Drosophila ommatidium. Dev. Biol. 120, 366-376.
    • (1987) Dev. Biol. , vol.120 , pp. 366-376
    • Tomlinson, A.1    Ready, D.F.2
  • 45
    • 0023649258 scopus 로고
    • Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila
    • Tomlinson, A., Bowtell, D.D., Hafen, E., and Rubin, G.M. (1987). Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila. Cell 51, 143-150.
    • (1987) Cell , vol.51 , pp. 143-150
    • Tomlinson, A.1    Bowtell, D.D.2    Hafen, E.3    Rubin, G.M.4
  • 46
    • 0030763928 scopus 로고    scopus 로고
    • Multiple regulatory domains on the Byr2 protein kinase
    • Tu, H., Barr, M., Dong, D.L., and Wigler, M. (1997). Multiple regulatory domains on the Byr2 protein kinase. Mol. Cell. Biol. 17, 5876-5887.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5876-5887
    • Tu, H.1    Barr, M.2    Dong, D.L.3    Wigler, M.4
  • 49
    • 0027267041 scopus 로고
    • Analysis of genetic mosaics in developing and adult Drosophila tissues
    • Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
    • (1993) Development , vol.117 , pp. 1223-1237
    • Xu, T.1    Rubin, G.M.2
  • 50
    • 0031974812 scopus 로고    scopus 로고
    • Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK
    • Yu, W., Fantl, W. J., Harrowe, G., and Williams, L.T. (1997). Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK. Curr. Biol. 8, 56-64.
    • (1997) Curr. Biol. , vol.8 , pp. 56-64
    • Yu, W.1    Fantl, W.J.2    Harrowe, G.3    Williams, L.T.4
  • 52
    • 0028353694 scopus 로고
    • Determination of neuronal cell fate: Lessons from the R7 neuron of Drosophila
    • Zipursky, S.L., and Rubin, G.M. (1994). Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. Annu. Rev. Neurosci. 17, 373-397.
    • (1994) Annu. Rev. Neurosci. , vol.17 , pp. 373-397
    • Zipursky, S.L.1    Rubin, G.M.2


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