Defective cAMP generation underlies the sensitivity of CNS neurons to neurofibromatosis-1 heterozygosity

Journal of Neuroscience

Volumn 30, Issue 16, 2010, Pages 5579-5589

  Brown, Jacquelyn A ^a   Gianino, Scott M ^a   Gutmann, David H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; FORSKOLIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NEUROFIBROMIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN; ROLIPRAM;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CRUSH TRAUMA; ENZYME INHIBITION; EXCITOTOXICITY; GENE EXPRESSION; GENETIC ENGINEERING; GROWTH CONE; HETEROZYGOSITY; HIPPOCAMPUS; IN VITRO STUDY; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NEURITE; NEUROFIBROMATOSIS; NEUROPROTECTION; NONHUMAN; OPTIC NERVE GLIOMA; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; RETINA GANGLION CELL; VISUAL IMPAIRMENT;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CYCLIC AMP; HETEROZYGOTE DETECTION; HIPPOCAMPUS; MICE; MICE, KNOCKOUT; NERVE CRUSH; NEUROFIBROMATOSIS 1; NEURONS; RETINAL GANGLION CELLS;

EID: 77951610854     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3994-09.2010     Document Type: Article

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