-
1
-
-
0034702207
-
Multiple endocrine neoplasia type 2B mutation in human RET oncogene induces medullary thyroid carcinoma in transgenic mice
-
ACTON, D. S., D. VELTHUYZEN, C. J. LIPS and J. W. HOPPENER, 2000 Multiple endocrine neoplasia type 2B mutation in human RET oncogene induces medullary thyroid carcinoma in transgenic mice. Oncogene 19: 3121-3125.
-
(2000)
Oncogene
, vol.19
, pp. 3121-3125
-
-
Acton, D.S.1
Velthuyzen, D.2
Lips, C.J.3
Hoppener, J.W.4
-
2
-
-
0034254857
-
NuRD and SIN3 histone deacetylase complexes in development
-
AHRINGER, J., 2000 NuRD and SIN3 histone deacetylase complexes in development. Trends Genet. 16: 351-356.
-
(2000)
Trends Genet.
, vol.16
, pp. 351-356
-
-
Ahringer, J.1
-
3
-
-
0028838086
-
Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations
-
ASAI, N., T. IWASHITA, M. MATSUYAMA and M. TAKAHASHI, 1995 Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations. Mol. Cell. Biol. 15: 1613-1619.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1613-1619
-
-
Asai, N.1
Iwashita, T.2
Matsuyama, M.3
Takahashi, M.4
-
4
-
-
0037279629
-
Analysis of Ras-induced overproliferation in Drosophila hemocytes
-
ASHA, H., I. NAGY, G. KOVACS, D. STETSON, I. ANDO et al., 2003 Analysis of Ras-induced overproliferation in Drosophila hemocytes. Genetics 163: 203-215.
-
(2003)
Genetics
, vol.163
, pp. 203-215
-
-
Asha, H.1
Nagy, I.2
Kovacs, G.3
Stetson, D.4
Ando, I.5
-
5
-
-
0026597693
-
Ellipse mutations in the Drosophila homologue of the EGF receptor affect pattern formation, cell division, and cell death in eye imaginal discs
-
BAKER, N. E., and G. M. RUBIN, 1992 Ellipse mutations in the Drosophila homologue of the EGF receptor affect pattern formation, cell division, and cell death in eye imaginal discs. Dev. Biol. 150: 381-396.
-
(1992)
Dev. Biol.
, vol.150
, pp. 381-396
-
-
Baker, N.E.1
Rubin, G.M.2
-
6
-
-
0035831039
-
The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye
-
BAKER, N. E., and S. Y. YU, 2001 The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye. Cell 104: 699-708.
-
(2001)
Cell
, vol.104
, pp. 699-708
-
-
Baker, N.E.1
Yu, S.Y.2
-
7
-
-
0032408664
-
Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex
-
BALOH, R. H., M. G. TANSEY, P. A. LAMPE, T. J. FAHRNER, H. ENOMOTO et al., 1998 Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 21: 1291-1302.
-
(1998)
Neuron
, vol.21
, pp. 1291-1302
-
-
Baloh, R.H.1
Tansey, M.G.2
Lampe, P.A.3
Fahrner, T.J.4
Enomoto, H.5
-
8
-
-
0034671913
-
Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase
-
BESSET, V., R. P. SCOTT and C. F. IBANEZ, 2000 Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. J. Biol. Chem. 275: 39159-39166.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39159-39166
-
-
Besset, V.1
Scott, R.P.2
Ibanez, C.F.3
-
9
-
-
0028269331
-
The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway
-
BIGGS, W. H., III, K. H. ZAVITZ, B. DICKSON, A. VAN DER STRATEN, D. BRUNNER et al., 1994 The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway. EMBO J. 13: 1628-1635.
-
(1994)
EMBO J.
, vol.13
, pp. 1628-1635
-
-
Biggs III, W.H.1
Zavitz, K.H.2
Dickson, B.3
Van Der Straten, A.4
Brunner, D.5
-
10
-
-
0024005329
-
Expression of an activated ras gene causes developmental abnormalities in transgenic Drosophila melanogaster
-
BISHOP, J. G., III, and V. G. CORCES, 1988 Expression of an activated ras gene causes developmental abnormalities in transgenic Drosophila melanogaster. Genes Dev. 2: 567-577.
-
(1988)
Genes Dev.
, vol.2
, pp. 567-577
-
-
Bishop III, J.G.1
Corces, V.G.2
-
11
-
-
0034693806
-
Selected glimpses into the activation and function of Src kinase
-
BJORGE, J. D., A. JAKYMIW and D. J. FUJITA, 2000 Selected glimpses into the activation and function of Src kinase. Oncogene 19: 5620-5635.
-
(2000)
Oncogene
, vol.19
, pp. 5620-5635
-
-
Bjorge, J.D.1
Jakymiw, A.2
Fujita, D.J.3
-
12
-
-
0035902180
-
Oncogenic kinase signalling
-
BLUME-JENSEN, P., and T. HUNTER, 2001 Oncogenic kinase signalling. Nature 411: 355-365.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
13
-
-
0026608238
-
The Son of sevenless gene product: A putative activator of Ras
-
BONFINI, L., C. A. KARLOVICH, C. DASGUPTA and U. BANERJEE, 1992 The Son of sevenless gene product: a putative activator of Ras. Science 255: 603-606.
-
(1992)
Science
, vol.255
, pp. 603-606
-
-
Bonfini, L.1
Karlovich, C.A.2
Dasgupta, C.3
Banerjee, U.4
-
14
-
-
0028233525
-
Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas
-
BONGARZONE, I., M. G. BUTTI, S. CORONELLI, M. G. BORRELLO, M. SANTORO et al., 1994 Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas. Cancer Res. 54: 2979-2985.
-
(1994)
Cancer Res.
, vol.54
, pp. 2979-2985
-
-
Bongarzone, I.1
Butti, M.G.2
Coronelli, S.3
Borrello, M.G.4
Santoro, M.5
-
15
-
-
9244251611
-
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
-
BORRELLO, M. G., L. ALBERTI, E. ARIGHI, I. BONGARZONE, C. BATTISTINI et al., 1996 The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma. Mol. Cell. Biol. 16: 2151-2163.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2151-2163
-
-
Borrello, M.G.1
Alberti, L.2
Arighi, E.3
Bongarzone, I.4
Battistini, C.5
-
16
-
-
0032504052
-
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
-
BOUTROS, M., N. PARICIO, D. I. STRUTT and M. MLODZIK, 1998 Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94: 109-118.
-
(1998)
Cell
, vol.94
, pp. 109-118
-
-
Boutros, M.1
Paricio, N.2
Strutt, D.I.3
Mlodzik, M.4
-
17
-
-
85047682409
-
Guidelines for diagnosis and therapy of MENtype 1 and type 2
-
BRANDI, M. L., R. F. GAGEL, A. ANGELI, J. P. BILEZIKIAN, P. BECK-PECCOZ et al., 2001 Guidelines for diagnosis and therapy of MENtype 1 and type 2. J. Clin. Endocrinol. Metab. 86: 5658-5671.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 5658-5671
-
-
Brandi, M.L.1
Gagel, R.F.2
Angeli, A.3
Bilezikian, J.P.4
Beck-Peccoz, P.5
-
18
-
-
18344410319
-
dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties
-
BREHM, A., G. LANGST, J. KEHLE, C. R. CLAPIER, A. IMHOF et al., 2000 dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties. EMBO J. 19: 4332-4341.
-
(2000)
EMBO J.
, vol.19
, pp. 4332-4341
-
-
Brehm, A.1
Langst, G.2
Kehle, J.3
Clapier, C.R.4
Imhof, A.5
-
19
-
-
0028173625
-
Null mutations in the alpha PS2 and beta PS integrin subunit genes have distinct phenotypes
-
BROWN, N. H., 1994 Null mutations in the alpha PS2 and beta PS integrin subunit genes have distinct phenotypes. Development 120: 1221-1231.
-
(1994)
Development
, vol.120
, pp. 1221-1231
-
-
Brown, N.H.1
-
20
-
-
0030925220
-
Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase
-
BUJ-BELLO, A., J. ADU, L. G. PINON, A. HORTON, J. THOMPSON et al., 1997 Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase. Nature 387: 721-724.
-
(1997)
Nature
, vol.387
, pp. 721-724
-
-
Buj-Bello, A.1
Adu, J.2
Pinon, L.G.3
Horton, A.4
Thompson, J.5
-
21
-
-
0034705571
-
Signaling through Ras is essential for ret oncogene-induced cell differentiation in PC12 cells
-
CALIFANO, D., C. RIZZO, A. D'ALESSIO, G. L. COLUCCI-D'AMATO, G. CALI et al., 2000 Signaling through Ras is essential for ret oncogene-induced cell differentiation in PC12 cells. J. Biol. Chem. 275: 19297-19305.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19297-19305
-
-
Califano, D.1
Rizzo, C.2
D'Alessio, A.3
Colucci-D'Amato, G.L.4
Cali, G.5
-
22
-
-
0028019769
-
Parent-of-origin effects in multiple endocrine neoplasia type 2B
-
CARLSON, K. M., J. BRACAMONTES, C. E. JACKSON, R. CLARK, A. LACROIX et al., 1994a Parent-of-origin effects in multiple endocrine neoplasia type 2B. Am. J. Hum. Genet. 55: 1076-1082.
-
(1994)
Am. J. Hum. Genet.
, vol.55
, pp. 1076-1082
-
-
Carlson, K.M.1
Bracamontes, J.2
Jackson, C.E.3
Clark, R.4
Lacroix, A.5
-
23
-
-
0027977002
-
Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B
-
USA
-
CARLSON, K. M., S. DOU, D. CHI, N. SCAVARDA, K. TOSHIMA et al., 1994b Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B. Proc. Natl. Acad. Sci. USA 91: 1579-1583.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 1579-1583
-
-
Carlson, K.M.1
Dou, S.2
Chi, D.3
Scavarda, N.4
Toshima, K.5
-
24
-
-
0037090983
-
Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm
-
CARMENA, A., E. BUFF, M. S. HALFON, S. GISSELBRECHT, F. JIMENEZ et al., 2002 Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm. Dev. Biol. 244: 226-242.
-
(2002)
Dev. Biol.
, vol.244
, pp. 226-242
-
-
Carmena, A.1
Buff, E.2
Halfon, M.S.3
Gisselbrecht, S.4
Jimenez, F.5
-
25
-
-
0037009074
-
N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts
-
CHARRASSE, S., M. MERIANE, F. COMUNALE, A. BLANGY and C. GAUTHIER-ROUVIERE, 2002 N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts. J. Cell Biol. 158: 953-965.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 953-965
-
-
Charrasse, S.1
Meriane, M.2
Comunale, F.3
Blangy, A.4
Gauthier-Rouviere, C.5
-
26
-
-
0034695921
-
Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength
-
CHELLAIAH, M., N. KIZER, M. SILVA, U. ALVAREZ, D. KWIATKOWSKI et al., 2000 Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength. J. Cell Biol. 148: 665-678.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 665-678
-
-
Chellaiah, M.1
Kizer, N.2
Silva, M.3
Alvarez, U.4
Kwiatkowski, D.5
-
27
-
-
0035960739
-
C. elegans Rb, NuRD, and Ras regulate lin-39-mediated cell fusion during vulval fate specification
-
CHEN, Z., and M. HAN, 2001 C. elegans Rb, NuRD, and Ras regulate lin-39-mediated cell fusion during vulval fate specification. Curr. Biol. 11: 1874-1879.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1874-1879
-
-
Chen, Z.1
Han, M.2
-
28
-
-
7144222747
-
Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKS): Evidence for a divergence of the ERKs and JNKs pathways induced by Ret
-
CHIARIELLO, M., R. VISCONTI, F. CARLOMAGNO, R. M. MELILLO, C. BUCCI et al., 1998 Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKS): evidence for a divergence of the ERKs and JNKs pathways induced by Ret. Oncogene 16: 2435-2445.
-
(1998)
Oncogene
, vol.16
, pp. 2435-2445
-
-
Chiariello, M.1
Visconti, R.2
Carlomagno, F.3
Melillo, R.M.4
Bucci, C.5
-
29
-
-
0031850609
-
Analysis of RET proto-oncogene abnormalities in patients with MEN 2A, MEN 2B, familial or sporadic medullary thyroid carcinoma
-
CHIEFARI, E., D. RUSSO, D. GIUFFRIDA, G. A. ZAMPA, D. MERINGOLO et al., 1998 Analysis of RET proto-oncogene abnormalities in patients with MEN 2A, MEN 2B, familial or sporadic medullary thyroid carcinoma. J. Endocrinol. Invest. 21: 358-364.
-
(1998)
J. Endocrinol. Invest.
, vol.21
, pp. 358-364
-
-
Chiefari, E.1
Russo, D.2
Giuffrida, D.3
Zampa, G.A.4
Meringolo, D.5
-
30
-
-
0041438719
-
Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model
-
CRANSTON, A. N., and B. A. J. PONDER, 2003 Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model. Cancer Res. 63: 4777-4780.
-
(2003)
Cancer Res.
, vol.63
, pp. 4777-4780
-
-
Cranston, A.N.1
Ponder, B.A.J.2
-
31
-
-
0037147129
-
Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors
-
CULLIS, D. N., B. PHILIP, J. D. BALEJA and L. A. FEIG, 2002 Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors. J. Biol. Chem. 277: 49158-49166.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49158-49166
-
-
Cullis, D.N.1
Philip, B.2
Baleja, J.D.3
Feig, L.A.4
-
32
-
-
0344244746
-
P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: Correlation of physical and cytogenetic maps in chromosomal region 86E-87F
-
DEAK, P., M. M. OMAR, R. D. SAUNDERS, M. PAL, O. KOMONYI et al., 1997 P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: correlation of physical and cytogenetic maps in chromosomal region 86E-87F. Genetics 147: 1697-1722.
-
(1997)
Genetics
, vol.147
, pp. 1697-1722
-
-
Deak, P.1
Omar, M.M.2
Saunders, R.D.3
Pal, M.4
Komonyi, O.5
-
33
-
-
0026679892
-
Raf functions downstream of Ras1 in the Sevenless signal transduction pathway
-
DICKSON, B., F. SPRENGER, D. MORRISON and E. HAFEN, 1992 Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360: 600-603.
-
(1992)
Nature
, vol.360
, pp. 600-603
-
-
Dickson, B.1
Sprenger, F.2
Morrison, D.3
Hafen, E.4
-
34
-
-
0031870959
-
Pten is essential for embryonic development and tumour suppression
-
Di Cristofano, A., B. Pesce, C. Cordon-Cardo and P. P. PANDOLFI, 1998 Pten is essential for embryonic development and tumour suppression. Nat. Genet. 19: 348-355.
-
(1998)
Nat. Genet.
, vol.19
, pp. 348-355
-
-
Di Cristofano, A.1
Pesce, B.2
Cordon-Cardo, C.3
Pandolfi, P.P.4
-
35
-
-
0031704474
-
Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis
-
DODSON, G. S., D. J. GUARNIERI and M. A. SIMON, 1998 Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis. Development 125: 2883-2892.
-
(1998)
Development
, vol.125
, pp. 2883-2892
-
-
Dodson, G.S.1
Guarnieri, D.J.2
Simon, M.A.3
-
36
-
-
0033561038
-
ebi regulates epidermal growth factor receptor signaling pathways in Drosophila
-
DONG, X., L. TSUDA, K. H. ZAVITZ, M. LIN, S. LI et al., 1999 ebi regulates epidermal growth factor receptor signaling pathways in Drosophila. Genes Dev. 13: 954-965.
-
(1999)
Genes Dev.
, vol.13
, pp. 954-965
-
-
Dong, X.1
Tsuda, L.2
Zavitz, K.H.3
Lin, M.4
Li, S.5
-
37
-
-
0027303248
-
Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC
-
DONIS-KELLER, H., S. DOU, D. CHI, K.M. CARLSON, K. TOSHIMA et al., 1993 Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. Hum. Mol. Genet. 2: 851-856.
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 851-856
-
-
Donis-Keller, H.1
Dou, S.2
Chi, D.3
Carlson, K.M.4
Toshima, K.5
-
38
-
-
15844422453
-
GDNF signalling through the Ret receptor tyrosine kinase
-
DURBEC, P., C. V. MARCOS-GUTIERREZ, C. KILKENNY, M. GRIGORIOU, K. WARTIOWAARA et al., 1996 GDNF signalling through the Ret receptor tyrosine kinase. Nature 381: 789-793.
-
(1996)
Nature
, vol.381
, pp. 789-793
-
-
Durbec, P.1
Marcos-Gutierrez, C.V.2
Kilkenny, C.3
Grigoriou, M.4
Wartiowaara, K.5
-
39
-
-
0024569718
-
The clinical and screening age-at-onset distribution for the MEN-2 syndrome
-
EASTON, D. F., M. A. PONDER, T. CUMMINGS, R. F. GAGEL, H. H. HANSEN et al., 1989 The clinical and screening age-at-onset distribution for the MEN-2 syndrome. Am. J. Hum. Genet. 44: 208-215.
-
(1989)
Am. J. Hum. Genet.
, vol.44
, pp. 208-215
-
-
Easton, D.F.1
Ponder, M.A.2
Cummings, T.3
Gagel, R.F.4
Hansen, H.H.5
-
40
-
-
0035282951
-
c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway
-
ENCINAS, M., M. G. TANSEY, B. A. TSUI-PIERCHALA, J. X. COMELLA, J. MILBRANDT et al., 2001 c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway. J. Neurosci. 21: 1464-1472.
-
(2001)
J. Neurosci.
, vol.21
, pp. 1464-1472
-
-
Encinas, M.1
Tansey, M.G.2
Tsui-Pierchala, B.A.3
Comella, J.X.4
Milbrandt, J.5
-
41
-
-
0028006092
-
Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours
-
ENG, C., D. P. SMITH, L. M. MULLIGAN, M. A. NAGAI, C. S. HEALEY et al., 1994 Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours. Hum. Mol. Genet. 3: 237-241.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 237-241
-
-
Eng, C.1
Smith, D.P.2
Mulligan, L.M.3
Nagai, M.A.4
Healey, C.S.5
-
42
-
-
4644256817
-
The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis
-
ENG, C., D. CLAYTON, I. SCHUFFENECKER, G. LENOIR, G. COTE et al., 1996 The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis. JAMA 276: 1575-1579.
-
(1996)
JAMA
, vol.276
, pp. 1575-1579
-
-
Eng, C.1
Clayton, D.2
Schuffenecker, I.3
Lenoir, G.4
Cote, G.5
-
43
-
-
0032504961
-
GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin
-
ENOKIDO, Y., F. DE SAUVAGE, J. A. HONGO, N. NINKINA, A. ROSENTHAL et al., 1998 GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. Curr. Biol. 8: 1019-1022.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1019-1022
-
-
Enokido, Y.1
De Sauvage, F.2
Hongo, J.A.3
Ninkina, N.4
Rosenthal, A.5
-
44
-
-
0032129239
-
GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys
-
ENOMOTO, H., T. ARAKI, A. JACKMAN, R. O. HEUCKEROTH, W. D. SNIDER et al., 1998 GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron 21: 317-324.
-
(1998)
Neuron
, vol.21
, pp. 317-324
-
-
Enomoto, H.1
Araki, T.2
Jackman, A.3
Heuckeroth, R.O.4
Snider, W.D.5
-
45
-
-
0034764503
-
RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons
-
ENOMOTO, H., P. A. CRAWFORD, A. GORODINSKY, R.O. HEUCKEROTH, E. M. JOHNSON, Jr. et al., 2001 RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. Development 128: 3963-3974.
-
(2001)
Development
, vol.128
, pp. 3963-3974
-
-
Enomoto, H.1
Crawford, P.A.2
Gorodinsky, A.3
Heuckeroth, R.O.4
Johnson Jr., E.M.5
-
46
-
-
0026575220
-
Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation
-
FORTINI, M. E., M. A. SIMON and G. M. RUBIN, 1992 Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature 355: 559-561.
-
(1992)
Nature
, vol.355
, pp. 559-561
-
-
Fortini, M.E.1
Simon, M.A.2
Rubin, G.M.3
-
47
-
-
0030584086
-
Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
-
FREEMAN, M., 1996 Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 87: 651-660.
-
(1996)
Cell
, vol.87
, pp. 651-660
-
-
Freeman, M.1
-
48
-
-
0032697488
-
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton
-
FU, C. A., M. SHEN, B. C. HUANG, J. LASAGA, D. G. PAYAN et al., 1999 TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton. J. Biol. Chem. 274: 30729-30737.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30729-30737
-
-
Fu, C.A.1
Shen, M.2
Huang, B.C.3
Lasaga, J.4
Payan, D.G.5
-
49
-
-
0037453706
-
MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer
-
FUJITA, N., D. L. JAYE, M. KAJITA, C. GEIGERMAN, C. S. MORENO et al., 2003 MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell 113: 207-219.
-
(2003)
Cell
, vol.113
, pp. 207-219
-
-
Fujita, N.1
Jaye, D.L.2
Kajita, M.3
Geigerman, C.4
Moreno, C.S.5
-
50
-
-
0029943447
-
Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein
-
GARRITY, P. A., Y. RAO, I. SALECKER, J. MCGLADE, T. PAWSON et al., 1996 Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. Cell 85: 639-650.
-
(1996)
Cell
, vol.85
, pp. 639-650
-
-
Garrity, P.A.1
Rao, Y.2
Salecker, I.3
McGlade, J.4
Pawson, T.5
-
51
-
-
0031955116
-
Consed: A graphical tool for sequence finishing
-
GORDON, D., C. ABAJIAN and P. GREEN, 1998 Consed: a graphical tool for sequence finishing. Genome Res. 8: 195-202.
-
(1998)
Genome Res.
, vol.8
, pp. 195-202
-
-
Gordon, D.1
Abajian, C.2
Green, P.3
-
52
-
-
0025022463
-
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
-
GRIECO, M., M. SANTORO, M. T. BERLINGIERI, R. M. MELILLO, R. DONGHI et al., 1990 PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. Cell 60: 557-563.
-
(1990)
Cell
, vol.60
, pp. 557-563
-
-
Grieco, M.1
Santoro, M.2
Berlingieri, M.T.3
Melillo, R.M.4
Donghi, R.5
-
53
-
-
85047677255
-
Expression pattern of Drosophila ret suggests a common ancestral origin between the metamorphosis precursors in insect endoderm and the vertebrate enteric neurons
-
USA
-
HAHN, M., and J. BISHOP, 2001 Expression pattern of Drosophila ret suggests a common ancestral origin between the metamorphosis precursors in insect endoderm and the vertebrate enteric neurons. Proc. Natl. Acad. Sci. USA 98: 1053-1058.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 1053-1058
-
-
Hahn, M.1
Bishop, J.2
-
54
-
-
0034981725
-
Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity
-
HALFAR, K., C. ROMMEL, H. STOCKER and E. HAFEN, 2001 Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development 128: 1687-1696.
-
(2001)
Development
, vol.128
, pp. 1687-1696
-
-
Halfar, K.1
Rommel, C.2
Stocker, H.3
Hafen, E.4
-
55
-
-
0034772594
-
GDNF and neurturin are target-derived factors essential for cranial parasympathetic neuron development
-
HASHINO, E., M. SHERO, D. JUNGHANS, H. ROHRER, J. MILBRANDT et al., 2001 GDNF and neurturin are target-derived factors essential for cranial parasympathetic neuron development. Development 128: 3773-3782.
-
(2001)
Development
, vol.128
, pp. 3773-3782
-
-
Hashino, E.1
Shero, M.2
Junghans, D.3
Rohrer, H.4
Milbrandt, J.5
-
56
-
-
0034648718
-
Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor
-
HAYASHI, H., M. ICHIHARA, T. IWASHITA, H. MURAKAMI, Y. SHIMONO et al., 2000 Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor. Oncogene 19: 4469-4475.
-
(2000)
Oncogene
, vol.19
, pp. 4469-4475
-
-
Hayashi, H.1
Ichihara, M.2
Iwashita, T.3
Murakami, H.4
Shimono, Y.5
-
57
-
-
0028910516
-
Growth and differentiation in the Drosophila eye coordinated by hedgehog
-
HEBERLEIN, U., C. M. SINGH, A. Y. LUK and T. J. DONOHOE, 1995 Growth and differentiation in the Drosophila eye coordinated by hedgehog. Nature 373: 709-711.
-
(1995)
Nature
, vol.373
, pp. 709-711
-
-
Heberlein, U.1
Singh, C.M.2
Luk, A.Y.3
Donohoe, T.J.4
-
58
-
-
0030963645
-
Absence of TP53 alterations in pheochromocytomas and medullary thyroid carcinomas
-
HERFARTH, K. K., M. R. WICK, H. N. MARSHALL, E. GARTNER, S. LUM et al., 1997 Absence of TP53 alterations in pheochromocytomas and medullary thyroid carcinomas. Genes Chromosomes Cancer 20: 24-29.
-
(1997)
Genes Chromosomes Cancer
, vol.20
, pp. 24-29
-
-
Herfarth, K.K.1
Wick, M.R.2
Marshall, H.N.3
Gartner, E.4
Lum, S.5
-
59
-
-
0032145723
-
Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro
-
HEUCKEROTH, R. O., P. A. LAMPE, E. M. JOHNSON and J. MILBRANDT, 1998 Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro. Dev. Biol. 200: 116-129.
-
(1998)
Dev. Biol.
, vol.200
, pp. 116-129
-
-
Heuckeroth, R.O.1
Lampe, P.A.2
Johnson, E.M.3
Milbrandt, J.4
-
60
-
-
0028174024
-
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
-
HOFSTRA, R. M., R. M. LANDSVATER, I. CECCHERINI, R. P. STULP, T. STELWAGEN et al., 1994 A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 367: 375-376.
-
(1994)
Nature
, vol.367
, pp. 375-376
-
-
Hofstra, R.M.1
Landsvater, R.M.2
Ceccherini, I.3
Stulp, R.P.4
Stelwagen, T.5
-
61
-
-
0033756163
-
A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster
-
HUANG, A. M., and G. M. RUBIN, 2000 A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster. Genetics 156: 1219-1230.
-
(2000)
Genetics
, vol.156
, pp. 1219-1230
-
-
Huang, A.M.1
Rubin, G.M.2
-
62
-
-
0033786922
-
Protein tyrosine kinase structure and function
-
HUBBARD, S. R., and J. H. TILL, 2000 Protein tyrosine kinase structure and function. Annu. Rev. Biochem. 69: 373-398.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 373-398
-
-
Hubbard, S.R.1
Till, J.H.2
-
63
-
-
0038412587
-
Neuroglian activates Echinoid to antagonize the Drosophila EGF receptor signaling pathway
-
ISLAM, R., S. Y. WEI, W. H. CHIU, M. HORTSCH and J. C. HSU, 2003 Neuroglian activates Echinoid to antagonize the Drosophila EGF receptor signaling pathway. Development 130: 2051-2059.
-
(2003)
Development
, vol.130
, pp. 2051-2059
-
-
Islam, R.1
Wei, S.Y.2
Chiu, W.H.3
Hortsch, M.4
Hsu, J.C.5
-
64
-
-
0030047832
-
Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation
-
IWASHITA, T., N. ASAI, H. MURAKAMI, M. MATSUYAMA and M. TAKAHASHI, 1996 Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation. Oncogene 12: 481-487.
-
(1996)
Oncogene
, vol.12
, pp. 481-487
-
-
Iwashita, T.1
Asai, N.2
Murakami, H.3
Matsuyama, M.4
Takahashi, M.5
-
65
-
-
0033166442
-
Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familialmedullary thyroid carcinoma
-
IWASHITA, T., M. KATO, H. MURAKAMI, N. ASAI, Y. ISHIGURO et al., 1999 Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familialmedullary thyroid carcinoma.Oncogene 18: 3919-3922.
-
(1999)
Oncogene
, vol.18
, pp. 3919-3922
-
-
Iwashita, T.1
Kato, M.2
Murakami, H.3
Asai, N.4
Ishiguro, Y.5
-
66
-
-
15844365303
-
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF
-
JING, S., D. WEN, Y. YU, P.L. HOLST, Y. LUO et al., 1996 GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85: 1113-1124.
-
(1996)
Cell
, vol.85
, pp. 1113-1124
-
-
Jing, S.1
Wen, D.2
Yu, Y.3
Holst, P.L.4
Luo, Y.5
-
67
-
-
0029869355
-
A screen for genes that function downstream of Ras1 during Drosophila eye development
-
KARIM, F. D., H. C. CHANG, M. THERRIEN, D. A. WASSARMAN, T. LAVERTY et al., 1996 A screen for genes that function downstream of Ras1 during Drosophila eye development. Genetics 143: 315-329.
-
(1996)
Genetics
, vol.143
, pp. 315-329
-
-
Karim, F.D.1
Chang, H.C.2
Therrien, M.3
Wassarman, D.A.4
Laverty, T.5
-
68
-
-
0034665364
-
Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation
-
KAWAI, K., T. IWASHITA, H. MURAKAMI, N. HIRAIWA, A. YOSHIKI et al., 2000 Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation. Cancer Res. 60: 5254-5260.
-
(2000)
Cancer Res.
, vol.60
, pp. 5254-5260
-
-
Kawai, K.1
Iwashita, T.2
Murakami, H.3
Hiraiwa, N.4
Yoshiki, A.5
-
69
-
-
0032484081
-
dMi-2, a hunchback-interacting protein that functions in polycomb repression
-
KEHLE, J., D. BEUCHLE, S. TREUHEIT, B. CHRISTEN, J. A. KENNISON et al., 1998 dMi-2, a hunchback-interacting protein that functions in polycomb repression. Science 282: 1897-1900.
-
(1998)
Science
, vol.282
, pp. 1897-1900
-
-
Kehle, J.1
Beuchle, D.2
Treuheit, S.3
Christen, B.4
Kennison, J.A.5
-
70
-
-
0025865768
-
Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas
-
KHOSLA, S., V. M. PATEL, I. D. HAY, D. J. SCHAID, C. S. GRANT et al., 1991 Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas. J. Clin. Invest. 87: 1691-1699.
-
(1991)
J. Clin. Invest.
, vol.87
, pp. 1691-1699
-
-
Khosla, S.1
Patel, V.M.2
Hay, I.D.3
Schaid, D.J.4
Grant, C.S.5
-
71
-
-
16944365682
-
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor
-
KLEIN, R. D., D. SHERMAN, W. H. HO, D. STONE, G. L. BENNETT et al., 1997 A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. Nature 387: 717-721.
-
(1997)
Nature
, vol.387
, pp. 717-721
-
-
Klein, R.D.1
Sherman, D.2
Ho, W.H.3
Stone, D.4
Bennett, G.L.5
-
72
-
-
0029827559
-
Neurturin, a relative of glial-cell-line-derived neurotrophic factor
-
KOTZBAUER, P. T., P. A. LAMPE, R.O. HEUCKEROTH, J. P. GOLDEN, D. J. CREEDON et al., 1996 Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 384: 467-470.
-
(1996)
Nature
, vol.384
, pp. 467-470
-
-
Kotzbauer, P.T.1
Lampe, P.A.2
Heuckeroth, R.O.3
Golden, J.P.4
Creedon, D.J.5
-
73
-
-
0035848684
-
Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction
-
KUROKAWA, K., T. IWASHITA, H. MURAKAMI, H. HAYASHI, K. KAWAI et al., 2001 Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction. Oncogene 20: 1929-1938.
-
(2001)
Oncogene
, vol.20
, pp. 1929-1938
-
-
Kurokawa, K.1
Iwashita, T.2
Murakami, H.3
Hayashi, H.4
Kawai, K.5
-
74
-
-
0038356894
-
Cell signalling and gene expression mediated by RET tyrosine kinase
-
KUROKAWA, K., K. KAWAI, M. HASHIMOTO, Y. ITO and M. TAKAHASHI, 2003 Cell signalling and gene expression mediated by RET tyrosine kinase. J. Intern. Med. 253: 627-633.
-
(2003)
J. Intern. Med.
, vol.253
, pp. 627-633
-
-
Kurokawa, K.1
Kawai, K.2
Hashimoto, M.3
Ito, Y.4
Takahashi, M.5
-
75
-
-
0035970893
-
Sterility of Drosophila with mutations in the Bloom syndrome gene - Complementation by Ku70
-
KUSANO, K., D.M. JOHNSON-SCHLITZ and W. R. ENGELS, 2001 Sterility of Drosophila with mutations in the Bloom syndrome gene - complementation by Ku70. Science 291: 2600-2602.
-
(2001)
Science
, vol.291
, pp. 2600-2602
-
-
Kusano, K.1
Johnson-Schlitz, D.M.2
Engels, W.R.3
-
76
-
-
0035949707
-
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
-
USA
-
KWABI-ADDO, B., D. GIRI, K. SCHMIDT, K. PODSYPANINA, R. PARSONS et al., 2001 Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. Proc. Natl. Acad. Sci. USA 98: 11563-11568.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 11563-11568
-
-
Kwabi-Addo, B.1
Giri, D.2
Schmidt, K.3
Podsypanina, K.4
Parsons, R.5
-
77
-
-
0026723089
-
Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein
-
LAI, Z. C., and G. M. RUBIN, 1992 Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein. Cell 70: 609-620.
-
(1992)
Cell
, vol.70
, pp. 609-620
-
-
Lai, Z.C.1
Rubin, G.M.2
-
78
-
-
0029931590
-
Loss of tramtrack gene activity results in ectopic R7 cell formation, even in a sina mutant background
-
USA
-
LAI, Z. C., S. D. HARRISON, F. KARIM, Y. LI and G. M. RUBIN, 1996 Loss of tramtrack gene activity results in ectopic R7 cell formation, even in a sina mutant background. Proc. Natl. Acad. Sci. USA 93: 5025-5030.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 5025-5030
-
-
Lai, Z.C.1
Harrison, S.D.2
Karim, F.3
Li, Y.4
Rubin, G.M.5
-
79
-
-
4644327063
-
Medullary thyroid carcinoma
-
LEBOULLEUX, S., E. BAUDIN, J. P. TRAVAGLI and M. SCHLUMBERGER, 2004 Medullary thyroid carcinoma. Clin. Endocrinol. 61: 299-310.
-
(2004)
Clin. Endocrinol.
, vol.61
, pp. 299-310
-
-
Leboulleux, S.1
Baudin, E.2
Travagli, J.P.3
Schlumberger, M.4
-
80
-
-
0035913906
-
Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila
-
LEE, J. R., S. URBAN, C. F. GARVEY and M. FREEMAN, 2001 Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. Cell 107: 161-171.
-
(2001)
Cell
, vol.107
, pp. 161-171
-
-
Lee, J.R.1
Urban, S.2
Garvey, C.F.3
Freeman, M.4
-
81
-
-
0032894310
-
Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila
-
LESOKHIN, A. M., S. Y. YU, J. KATZ and N. E. BAKER, 1999 Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila. Dev. Biol. 205: 129-144.
-
(1999)
Dev. Biol.
, vol.205
, pp. 129-144
-
-
Lesokhin, A.M.1
Yu, S.Y.2
Katz, J.3
Baker, N.E.4
-
82
-
-
10744230697
-
A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes
-
USA
-
LEY, T. J., P. J. MINX, M. J. WALTER, R. E. RIES, H. SUN et al., 2003 A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc. Natl. Acad. Sci. USA 100: 14275-14280.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 14275-14280
-
-
Ley, T.J.1
Minx, P.J.2
Walter, M.J.3
Ries, R.E.4
Sun, H.5
-
83
-
-
0029923448
-
Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities
-
LIU, X., Q. C. VEGA, R. A. DECKER, A. PANDEY, C. A. WORBY et al., 1996 Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities. J. Biol. Chem. 271: 5309-5312.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5309-5312
-
-
Liu, X.1
Vega, Q.C.2
Decker, R.A.3
Pandey, A.4
Worby, C.A.5
-
84
-
-
0032430747
-
A screen for mutations that prevent lethality caused by expression of activated sevenless and Ras1 in the Drosophila embryo
-
MAIXNER, A., T. P. HECKER, Q. N. PHAN and D. A. WASSARMAN, 1998 A screen for mutations that prevent lethality caused by expression of activated sevenless and Ras1 in the Drosophila embryo. Dev. Genet. 23: 347-361.
-
(1998)
Dev. Genet.
, vol.23
, pp. 347-361
-
-
Maixner, A.1
Hecker, T.P.2
Phan, Q.N.3
Wassarman, D.A.4
-
85
-
-
0037683649
-
Genome-wide copy number imbalances identified in familial and sporadic medullary thyroid carcinoma
-
MARSH, D. J., G. THEODOSOPOULOS, K. MARTIN-SCHULTE, A. L. RICHARDSON, J. PHILIPS et al., 2003 Genome-wide copy number imbalances identified in familial and sporadic medullary thyroid carcinoma. J. Clin. Endocrinol. Metab. 88: 1866-1872.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 1866-1872
-
-
Marsh, D.J.1
Theodosopoulos, G.2
Martin-Schulte, K.3
Richardson, A.L.4
Philips, J.5
-
86
-
-
15144348923
-
Expression of multiple endocrine neoplasia 2B RET in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behavior in vivo, and activates Jun kinase
-
MARSHALL, G. M., A. E. PEASTON, J. E. HOCKER, S. A. SMITH, L. M. HANSFORD et al., 1997 Expression of multiple endocrine neoplasia 2B RET in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behavior in vivo, and activates Jun kinase. Cancer Res. 57: 5399-5405.
-
(1997)
Cancer Res.
, vol.57
, pp. 5399-5405
-
-
Marshall, G.M.1
Peaston, A.E.2
Hocker, J.E.3
Smith, S.A.4
Hansford, L.M.5
-
87
-
-
0033375113
-
Repression of the wing vein development in Drosophila by the nuclear matrix protein plexus
-
MATAKATSU, H., R. TADOKORO, S. GAMO and S. HAYASHI, 1999 Repression of the wing vein development in Drosophila by the nuclear matrix protein plexus. Development 126: 5207-5216.
-
(1999)
Development
, vol.126
, pp. 5207-5216
-
-
Matakatsu, H.1
Tadokoro, R.2
Gamo, S.3
Hayashi, S.4
-
88
-
-
0028958488
-
Proliferative activity in C-cell hyperplasia and medullary thyroid carcinoma. Evaluation by PCNA immunohistochemistry and AgNORs staining
-
MATIAS-GUIU, X., G. PEIRO, J. ESQUIUS, E. OLIVA, R. CABEZAS et al., 1995 Proliferative activity in C-cell hyperplasia and medullary thyroid carcinoma. Evaluation by PCNA immunohistochemistry and AgNORs staining. Pathol. Res. Pract. 191: 42-47.
-
(1995)
Pathol. Res. Pract.
, vol.191
, pp. 42-47
-
-
Matias-Guiu, X.1
Peiro, G.2
Esquius, J.3
Oliva, E.4
Cabezas, R.5
-
89
-
-
0033104338
-
Ret-mediated mitogenesis requires Src kinase activity
-
MELILLO, R. M., M. V. BARONE, G. LUPOLI, A. M. CIRAFICI, F. CARLOMAGNO et al., 1999 Ret-mediated mitogenesis requires Src kinase activity. Cancer Res. 59: 1120-1126.
-
(1999)
Cancer Res.
, vol.59
, pp. 1120-1126
-
-
Melillo, R.M.1
Barone, M.V.2
Lupoli, G.3
Cirafici, A.M.4
Carlomagno, F.5
-
90
-
-
0034967978
-
Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade
-
MELILLO, R. M., M. SANTORO, S.H. ONG, M. BILLAUD, A. FUSCO et al., 2001 Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade. Mol. Cell. Biol. 21: 4177-4187.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4177-4187
-
-
Melillo, R.M.1
Santoro, M.2
Ong, S.H.3
Billaud, M.4
Fusco, A.5
-
91
-
-
0036148536
-
Atypical MEN type 2B associated with two germline RET mutations on the same allele not involving codon 918
-
MENKO, F. H., R. B. VAN DER LUIJT, I.A. DE VALK, A.W. TOORIANS, J. M. SEPERS et al., 2002 Atypical MEN type 2B associated with two germline RET mutations on the same allele not involving codon 918. J. Clin. Endocrinol. Metab. 87: 393-397.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 393-397
-
-
Menko, F.H.1
Van Der Luijt, R.B.2
De Valk, I.A.3
Toorians, A.W.4
Sepers, J.M.5
-
92
-
-
0030902536
-
Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation
-
USA
-
MICHIELS, F. M., S. CHAPPUIS, B. CAILLOU, A. PASINI, M. TALBOT et al., 1997 Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation. Proc. Natl. Acad. Sci. USA 94: 3330-3335.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 3330-3335
-
-
Michiels, F.M.1
Chappuis, S.2
Caillou, B.3
Pasini, A.4
Talbot, M.5
-
93
-
-
0032005510
-
Persephin, a novel neurotrophic factor related to GDNF and neurturin
-
MILBRANDT, J., F. J. DE SAUVAGE, T. J. FAHRNER, R. H. BALOH, M. L. LEITNER et al., 1998 Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron 20: 245-253.
-
(1998)
Neuron
, vol.20
, pp. 245-253
-
-
Milbrandt, J.1
De Sauvage, F.J.2
Fahrner, T.J.3
Baloh, R.H.4
Leitner, M.L.5
-
94
-
-
0031815368
-
Local induction of patterning and programmed cell death in the developing Drosophila retina
-
MILLER, D. T., and R. L. CAGAN, 1998 Local induction of patterning and programmed cell death in the developing Drosophila retina. Development 125: 2327-2335.
-
(1998)
Development
, vol.125
, pp. 2327-2335
-
-
Miller, D.T.1
Cagan, R.L.2
-
95
-
-
0035400394
-
Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET protooncogene: Modeling studies
-
MILLER, M., K. GINALSKI, B. LESYNG, N. NAKAIGAWA, L. SCHMIDT et al., 2001 Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET protooncogene: modeling studies. Proteins 44: 32-43.
-
(2001)
Proteins
, vol.44
, pp. 32-43
-
-
Miller, M.1
Ginalski, K.2
Lesyng, B.3
Nakaigawa, N.4
Schmidt, L.5
-
96
-
-
0033045514
-
Two germline missense mutations at codons 804 and 806 of the RET proto-oncogene in the same allele in a patient with multiple endocrine neoplasia type 2B without codon 918 mutation
-
MIYAUCHI, A., H. FUTAMI, N. HAI, T. YOKOZAWA, K. KUMA et al., 1999 Two germline missense mutations at codons 804 and 806 of the RET proto-oncogene in the same allele in a patient with multiple endocrine neoplasia type 2B without codon 918 mutation. Jpn. J. Cancer Res. 90: 1-5.
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 1-5
-
-
Miyauchi, A.1
Futami, H.2
Hai, N.3
Yokozawa, T.4
Kuma, K.5
-
97
-
-
0035921928
-
Archipelago regulates cyclin e levels in Drosophila and is mutated in human cancer cell lines
-
MOBERG, K. H., D. W. BELL, D. C. WAHRER, D. A. HABER and I. K. HARIHARAN, 2001 Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature 413: 311-316.
-
(2001)
Nature
, vol.413
, pp. 311-316
-
-
Moberg, K.H.1
Bell, D.W.2
Wahrer, D.C.3
Haber, D.A.4
Hariharan, I.K.5
-
98
-
-
0027410857
-
Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2
-
MULLIGAN, L. M., E. GARDNER, B. A. SMITH, C. G. MATHEW and B. A. PONDER, 1993a Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2. Genes Chromosomes Cancer 6: 166-177.
-
(1993)
Genes Chromosomes Cancer
, vol.6
, pp. 166-177
-
-
Mulligan, L.M.1
Gardner, E.2
Smith, B.A.3
Mathew, C.G.4
Ponder, B.A.5
-
99
-
-
0027231568
-
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
-
MULLIGAN, L. M., J. B. KWOK, C. S. HEALEY, M. J. ELSDON, C. ENG et al., 1993b Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature 363: 458-460.
-
(1993)
Nature
, vol.363
, pp. 458-460
-
-
Mulligan, L.M.1
Kwok, J.B.2
Healey, C.S.3
Elsdon, M.J.4
Eng, C.5
-
100
-
-
0028199074
-
Specific mutations of the RET proto-oncogene are related to disease phenotype inMEN 2A and FMTC
-
MULLIGAN, L. M., C. ENG, C. S. HEALEY, D. CLAYTON, J. B. KWOK et al., 1994a Specific mutations of the RET proto-oncogene are related to disease phenotype inMEN 2A and FMTC. Nat. Genet. 6: 70-74.
-
(1994)
Nat. Genet.
, vol.6
, pp. 70-74
-
-
Mulligan, L.M.1
Eng, C.2
Healey, C.S.3
Clayton, D.4
Kwok, J.B.5
-
101
-
-
0028206298
-
A de novo mutation of the RET proto-oncogene in a patient with MEN 2A
-
MULLIGAN, L. M., C. ENG, C. S. HEALEY, M. A. PONDER, G. L. FELDMAN et al., 1994b A de novo mutation of the RET proto-oncogene in a patient with MEN 2A. Hum. Mol. Genet. 3: 1007-1008.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 1007-1008
-
-
Mulligan, L.M.1
Eng, C.2
Healey, C.S.3
Ponder, M.A.4
Feldman, G.L.5
-
102
-
-
0033580391
-
Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase
-
MURAKAMI, H., T. IWASHITA, N. ASAI, Y. IWATA, S. NARUMIYA et al., 1999a Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase. Oncogene 18: 1975-1982.
-
(1999)
Oncogene
, vol.18
, pp. 1975-1982
-
-
Murakami, H.1
Iwashita, T.2
Asai, N.3
Iwata, Y.4
Narumiya, S.5
-
103
-
-
0033584474
-
Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation
-
MURAKAMI, H., T. IWASHITA, N. ASAI, Y. SHIMONO, Y. IWATA et al., 1999b Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation. Biochem. Biophys. Res. Commun. 262: 68-75.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.262
, pp. 68-75
-
-
Murakami, H.1
Iwashita, T.2
Asai, N.3
Shimono, Y.4
Iwata, Y.5
-
104
-
-
0035680733
-
Tramtrack69 interacts with the dMi-2 subunit of the Drosophila NuRD chromatin remodelling complex
-
MURAWSKY, C. M., A. BREHM, P. BADENHORST, N. LOWE, P. B. BECKER et al., 2001 Tramtrack69 interacts with the dMi-2 subunit of the Drosophila NuRD chromatin remodelling complex. EMBO Rep. 2: 1089-1094.
-
(2001)
EMBO Rep.
, vol.2
, pp. 1089-1094
-
-
Murawsky, C.M.1
Brehm, A.2
Badenhorst, P.3
Lowe, N.4
Becker, P.B.5
-
105
-
-
0036832278
-
Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis
-
NATARAJAN, D., C. MARCOS-GUTIERREZ, V. PACHNIS and E. DE GRAAFF, 2002 Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis. Development 129: 5151-5160.
-
(2002)
Development
, vol.129
, pp. 5151-5160
-
-
Natarajan, D.1
Marcos-Gutierrez, C.2
Pachnis, V.3
De Graaff, E.4
-
106
-
-
0031882496
-
A genetic screen to identify components of the sina signaling pathway in Drosophila eye development
-
NEUFELD, T. P., A. H. TANG and G. M. RUBIN, 1998 A genetic screen to identify components of the sina signaling pathway in Drosophila eye development. Genetics 148: 277-286.
-
(1998)
Genetics
, vol.148
, pp. 277-286
-
-
Neufeld, T.P.1
Tang, A.H.2
Rubin, G.M.3
-
107
-
-
0030872838
-
PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing
-
NICKERSON, D. A., V. O. TOBE and S. L. TAYLOR, 1997 PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing. Nucleic Acids Res. 25: 2745-2751.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2745-2751
-
-
Nickerson, D.A.1
Tobe, V.O.2
Taylor, S.L.3
-
108
-
-
0031589554
-
Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations
-
OHIWA, M., H. MURAKAMI, T. IWASHITA, N. ASAI, Y. IWATA et al., 1997 Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations. Biochem. Biophys. Res. Commun. 237: 747-751.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 747-751
-
-
Ohiwa, M.1
Murakami, H.2
Iwashita, T.3
Asai, N.4
Iwata, Y.5
-
109
-
-
0028970587
-
p80/85 cortactin associates with the Src SH2 domain and colocalizes with v-Src in transformed cells
-
OKAMURA, H., and M. D. RESH, 1995 p80/85 cortactin associates with the Src SH2 domain and colocalizes with v-Src in transformed cells. J. Biol. Chem. 270: 26613-26618.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26613-26618
-
-
Okamura, H.1
Resh, M.D.2
-
110
-
-
0028850669
-
Multiple endocrine neoplasia type 2B: More than an endocrine disorder
-
O'RIORDAIN, D. S., T. O'BRIEN, T. B. CROTTY, H. GHARIB, C. S. GRANT et al., 1995 Multiple endocrine neoplasia type 2B: more than an endocrine disorder. Surgery 118: 936-942.
-
(1995)
Surgery
, vol.118
, pp. 936-942
-
-
O'Riordain, D.S.1
O'Brien, T.2
Crotty, T.B.3
Gharib, H.4
Grant, C.S.5
-
111
-
-
0033200204
-
The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling
-
PARICIO, N., F. FEIGUIN, M. BOUTROS, S. EATON and M. MLODZIK, 1999 The Drosophila STE20-like kinase misshapen is required downstream of the Frizzled receptor in planar polarity signaling. EMBO J. 18: 4669-4678.
-
(1999)
EMBO J.
, vol.18
, pp. 4669-4678
-
-
Paricio, N.1
Feiguin, F.2
Boutros, M.3
Eaton, S.4
Mlodzik, M.5
-
112
-
-
0028955264
-
Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers
-
PEIFFER, S. L., T. J. HERZOG, D. J. TRIBUNE,D. G. MUTCH, D. J. GERSELL et al., 1995 Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers. Cancer Res. 55: 1922-1926.
-
(1995)
Cancer Res.
, vol.55
, pp. 1922-1926
-
-
Peiffer, S.L.1
Herzog, T.J.2
Tribune, D.J.3
Mutch, D.G.4
Gersell, D.J.5
-
113
-
-
0031730382
-
The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability
-
PENNETTA, G., and D. PAULI, 1998 The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability. Dev. Genes Evol. 208: 531-536.
-
(1998)
Dev. Genes Evol.
, vol.208
, pp. 531-536
-
-
Pennetta, G.1
Pauli, D.2
-
114
-
-
0033119329
-
The phenotypes associated with ret mutations in the multiple endocrine neoplasia type 2 syndrome
-
PONDER, B. A., 1999 The phenotypes associated with ret mutations in the multiple endocrine neoplasia type 2 syndrome. Cancer Res. 59: 1736s-1741s; discussion 1742s.
-
(1999)
Cancer Res.
, vol.59
-
-
Ponder, B.A.1
-
115
-
-
0033200353
-
A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila
-
PROKOPENKO, S. N., A. BRUMBY, L. O'KEEFE, L. PRIOR, Y. HE et al., 1999 A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila. Genes Dev. 13: 2301-2314.
-
(1999)
Genes Dev.
, vol.13
, pp. 2301-2314
-
-
Prokopenko, S.N.1
Brumby, A.2
O'Keefe, L.3
Prior, L.4
He, Y.5
-
116
-
-
14644446016
-
Medullary thyroid carcinoma: Including MEN 2A and MEN 2B syndromes
-
QUAYLE, F. J., and J. F. MOLEY, 2005 Medullary thyroid carcinoma: including MEN 2A and MEN 2B syndromes. J. Surg. Oncol. 89: 122-129.
-
(2005)
J. Surg. Oncol.
, vol.89
, pp. 122-129
-
-
Quayle, F.J.1
Moley, J.F.2
-
117
-
-
3242700398
-
Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways
-
READ, R. D., E. A. BACH and R. L. CAGAN, 2004 Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways. Mol. Cell. Biol. 24: 6676-6689.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6676-6689
-
-
Read, R.D.1
Bach, E.A.2
Cagan, R.L.3
-
118
-
-
0033962585
-
A genetic screen for novel components of theRas/mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein
-
REBAY, I., F. CHEN, F. HSIAO, P. A. KOLODZIEJ, B. H. KUANG et al., 2000 A genetic screen for novel components of theRas/mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein. Genetics 154: 695-712.
-
(2000)
Genetics
, vol.154
, pp. 695-712
-
-
Rebay, I.1
Chen, F.2
Hsiao, F.3
Kolodziej, P.A.4
Kuang, B.H.5
-
119
-
-
0037102252
-
Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage
-
REICH, A., and B. Z. SHILO, 2002 Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage. EMBO J. 21: 4287-4296.
-
(2002)
EMBO J.
, vol.21
, pp. 4287-4296
-
-
Reich, A.1
Shilo, B.Z.2
-
120
-
-
0033230857
-
The SH2/SH3 adaptor protein dock interacts with the Ste20-like kinase misshapen in controlling growth cone motility
-
RUAN, W., P. Pang and Y. RAO, 1999 The SH2/SH3 adaptor protein dock interacts with the Ste20-like kinase misshapen in controlling growth cone motility. Neuron 24: 595-605.
-
(1999)
Neuron
, vol.24
, pp. 595-605
-
-
Ruan, W.1
Pang, P.2
Rao, Y.3
-
121
-
-
0037028055
-
Bifocal is a downstream target of the Ste20-like serine/threonine kinase misshapen in regulating photoreceptor growth cone targeting in Drosophila
-
RUAN, W., H. LONG, D. H. VUONG and Y. RAO, 2002 Bifocal is a downstream target of the Ste20-like serine/threonine kinase misshapen in regulating photoreceptor growth cone targeting in Drosophila. Neuron 36: 831-842.
-
(2002)
Neuron
, vol.36
, pp. 831-842
-
-
Ruan, W.1
Long, H.2
Vuong, D.H.3
Rao, Y.4
-
122
-
-
0035866411
-
Increased in vivo phosphorylation of ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B
-
SALVATORE, D., R. M. MELILLO, C. MONACO, R. VISCONTI, G. FENZI et al., 2001 Increased in vivo phosphorylation of ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B. Cancer Res. 61: 1426-1431.
-
(2001)
Cancer Res.
, vol.61
, pp. 1426-1431
-
-
Salvatore, D.1
Melillo, R.M.2
Monaco, C.3
Visconti, R.4
Fenzi, G.5
-
123
-
-
0030867095
-
P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster : Mutations affecting embryonic PNS development
-
SALZBERG, A., S. N. PROKOPENKO, Y. HE, P. TSAI, M. PAL et al., 1997 P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster : mutations affecting embryonic PNS development. Genetics 147: 1723-1741.
-
(1997)
Genetics
, vol.147
, pp. 1723-1741
-
-
Salzberg, A.1
Prokopenko, S.N.2
He, Y.3
Tsai, P.4
Pal, M.5
-
124
-
-
0029901727
-
Renal agenesis and the absence of enteric neurons in mice lacking GDNF
-
SANCHEZ, M. P., I. SILOS-SANTIAGO, J. FRISEN, B. HE, S. A. LIRA et al., 1996 Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382: 70-73.
-
(1996)
Nature
, vol.382
, pp. 70-73
-
-
Sanchez, M.P.1
Silos-Santiago, I.2
Frisen, J.3
He, B.4
Lira, S.A.5
-
125
-
-
2542432915
-
Haploinsufficiency for tumour suppressor genes: When you don't need to go all the way
-
SANTAROSA, M., and A. ASHWORTH, 2004 Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way. Biochim. Biophys. Acta 1654: 105-122.
-
(2004)
Biochim. Biophys. Acta
, vol.1654
, pp. 105-122
-
-
Santarosa, M.1
Ashworth, A.2
-
126
-
-
0028914683
-
Activation of RETas a dominant transforming gene by germline mutations of MEN2A and MEN2B
-
SANTORO, M., F. CARLOMAGNO, A. ROMANO, D. P. BOTTARO, N. A. DATHAN et al., 1995 Activation of RETas a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science 267: 381-383.
-
(1995)
Science
, vol.267
, pp. 381-383
-
-
Santoro, M.1
Carlomagno, F.2
Romano, A.3
Bottaro, D.P.4
Dathan, N.A.5
-
127
-
-
0031850872
-
Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway
-
SAWAMOTO, K., A. TAGUCHI, Y. HIROTA, C. YAMADA, M. H. JIN et al., 1998 Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway. Cell Death Differ. 5: 262-270.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 262-270
-
-
Sawamoto, K.1
Taguchi, A.2
Hirota, Y.3
Yamada, C.4
Jin, M.H.5
-
128
-
-
0028174023
-
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
-
SCHUCHARDT, A., V. D'AGATI, L. LARSSON-BLOMBERG, F. COSTANTINI and V. PACHNIS, 1994 Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367: 380-383.
-
(1994)
Nature
, vol.367
, pp. 380-383
-
-
Schuchardt, A.1
D'Agati, V.2
Larsson-Blomberg, L.3
Costantini, F.4
Pachnis, V.5
-
129
-
-
0032512688
-
Germline and somatic mutations of the RET proto-oncogene in apparently sporadic medullary thyroid carcinomas
-
SCURINI, C., L. QUADRO, O. FATTORUSO, U. VERGA, A. LIBROIA et al., 1998 Germline and somatic mutations of the RET proto-oncogene in apparently sporadic medullary thyroid carcinomas. Mol. Cell. Endocrinol. 137: 51-57.
-
(1998)
Mol. Cell. Endocrinol.
, vol.137
, pp. 51-57
-
-
Scurini, C.1
Quadro, L.2
Fattoruso, O.3
Verga, U.4
Libroia, A.5
-
130
-
-
0034603172
-
Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway
-
SEGOUFFIN-CARIOU, C., and M. BILLAUD, 2000 Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway. J. Biol. Chem. 275: 3568-3576.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3568-3576
-
-
Segouffin-Cariou, C.1
Billaud, M.2
-
131
-
-
0031626942
-
Mutational analysis of the RET proto-oncogene in 71 Japanese patients with medullary thyroid carcinoma
-
SHIRAHAMA, S., K. OGURA, H. TAKAMI, K. ITO, T. TOHSEN et al., 1998 Mutational analysis of the RET proto-oncogene in 71 Japanese patients with medullary thyroid carcinoma. J. Hum. Genet. 43: 101-106.
-
(1998)
J. Hum. Genet.
, vol.43
, pp. 101-106
-
-
Shirahama, S.1
Ogura, K.2
Takami, H.3
Ito, K.4
Tohsen, T.5
-
132
-
-
0034730323
-
Receptor tyrosine kinases: Specific outcomes from general signals
-
SIMON, M. A., 2000 Receptor tyrosine kinases: specific outcomes from general signals. Cell 103: 13-15.
-
(2000)
Cell
, vol.103
, pp. 13-15
-
-
Simon, M.A.1
-
133
-
-
0025997867
-
Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
-
SIMON, M. A., D. D. BOWTELL, G. S. DODSON, T. R. LAVERTY and G. M. RUBIN, 1991 Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67: 701-716.
-
(1991)
Cell
, vol.67
, pp. 701-716
-
-
Simon, M.A.1
Bowtell, D.D.2
Dodson, G.S.3
Laverty, T.R.4
Rubin, G.M.5
-
134
-
-
0030828048
-
Germline mutation of RET codon 883 in two cases of de novo MEN 2B
-
SMITH, D. P., C. HOUGHTON and B. A. PONDER, 1997 Germline mutation of RET codon 883 in two cases of de novo MEN 2B. Oncogene 15: 1213-1217.
-
(1997)
Oncogene
, vol.15
, pp. 1213-1217
-
-
Smith, D.P.1
Houghton, C.2
Ponder, B.A.3
-
135
-
-
0034651526
-
C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B
-
SMITH-HICKS, C. L., K. C. SIZER, J. F. POWERS, A. S. TISCHLER and F. COSTANTINI, 2000 C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in a mouse model of multiple endocrine neoplasia type 2B. EMBO J. 19: 612-622.
-
(2000)
EMBO J.
, vol.19
, pp. 612-622
-
-
Smith-Hicks, C.L.1
Sizer, K.C.2
Powers, J.F.3
Tischler, A.S.4
Costantini, F.5
-
136
-
-
0032998903
-
The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning
-
SOLARI, F., A. BATEMAN and J. AHRINGER, 1999 The Caenorhabditis elegans genes egl-27 and egr-1 are similar to MTA1, a member of a chromatin regulatory complex, and are redundantly required for embryonic patterning. Development 126: 2483-2494.
-
(1999)
Development
, vol.126
, pp. 2483-2494
-
-
Solari, F.1
Bateman, A.2
Ahringer, J.3
-
137
-
-
0033232936
-
Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons
-
SOLER, R. M., X. DOLCET, M. ENCINAS, J. EGEA, J. R. BAYASCAS et al., 1999 Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons. J. Neurosci. 19: 9160-9169.
-
(1999)
J. Neurosci.
, vol.19
, pp. 9160-9169
-
-
Soler, R.M.1
Dolcet, X.2
Encinas, M.3
Egea, J.4
Bayascas, J.R.5
-
138
-
-
0028938721
-
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
-
SONGYANG, Z., K. CARRAWAY, M. ECK, S.HARRISON, R. FELDMAN et al., 1995 Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature 373: 536-539.
-
(1995)
Nature
, vol.373
, pp. 536-539
-
-
Songyang, Z.1
Carraway, K.2
Eck, M.3
Harrison, S.4
Feldman, R.5
-
139
-
-
0037413625
-
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity
-
SPECK, O., S. C. HUGHES, N. K. NOREN, R.M. KULIKAUSKAS and R. G. FEHON, 2003 Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature 421: 83-87.
-
(2003)
Nature
, vol.421
, pp. 83-87
-
-
Speck, O.1
Hughes, S.C.2
Noren, N.K.3
Kulikauskas, R.M.4
Fehon, R.G.5
-
140
-
-
0041534390
-
Echinoid is essential for regulation of Egfr signaling and R8 formation during Drosophila eye development
-
SPENCER, S. A., and R. L. CAGAN, 2003 Echinoid is essential for regulation of Egfr signaling and R8 formation during Drosophila eye development. Development 130: 3725-3733.
-
(2003)
Development
, vol.130
, pp. 3725-3733
-
-
Spencer, S.A.1
Cagan, R.L.2
-
141
-
-
0032436618
-
Regulation of EGF receptor signaling establishes pattern across the developing Drosophila retina
-
SPENCER, S. A., P. A. POWELL, D. T. MILLER and R. L. CAGAN, 1998 Regulation of EGF receptor signaling establishes pattern across the developing Drosophila retina. Development 125: 4777-4790.
-
(1998)
Development
, vol.125
, pp. 4777-4790
-
-
Spencer, S.A.1
Powell, P.A.2
Miller, D.T.3
Cagan, R.L.4
-
142
-
-
0032883802
-
The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes
-
SPRADLING, A. C., D. STERN, A. BEATON, E. J. RHEM, T. LAVERTY et al., 1999 The Berkeley Drosophila Genome Project gene disruption project: single P-element insertions mutating 25% of vital Drosophila genes. Genetics 153: 135-177.
-
(1999)
Genetics
, vol.153
, pp. 135-177
-
-
Spradling, A.C.1
Stern, D.2
Beaton, A.3
Rhem, E.J.4
Laverty, T.5
-
143
-
-
0142092607
-
A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila
-
STEWART, R. A., D.-M. LI, H. HUANG and T. XU, 2003 A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila. Oncogene 22: 6436-6444.
-
(2003)
Oncogene
, vol.22
, pp. 6436-6444
-
-
Stewart, R.A.1
Li, D.-M.2
Huang, H.3
Xu, T.4
-
144
-
-
0029901861
-
CHD1 is concentrated in interbands and puffed regions of Drosophila polytene chromosomes
-
USA
-
STOKES, D. G., K. D. TARTOF and R. P. PERRY, 1996 CHD1 is concentrated in interbands and puffed regions of Drosophila polytene chromosomes. Proc. Natl. Acad. Sci. USA 93: 7137-7142.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 7137-7142
-
-
Stokes, D.G.1
Tartof, K.D.2
Perry, R.P.3
-
145
-
-
0032146918
-
The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway
-
SU, Y. C., J. E. TREISMAN and E. Y. SKOLNIK, 1998 The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway. Genes Dev. 12: 2371-2380.
-
(1998)
Genes Dev.
, vol.12
, pp. 2371-2380
-
-
Su, Y.C.1
Treisman, J.E.2
Skolnik, E.Y.3
-
146
-
-
0028096097
-
A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells
-
SUGAYA, R., S. ISHIMARU, T. HOSOYA, K. SAIGO and Y. EMORI, 1994 A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells. Mech. Dev. 45: 139-145.
-
(1994)
Mech. Dev.
, vol.45
, pp. 139-145
-
-
Sugaya, R.1
Ishimaru, S.2
Hosoya, T.3
Saigo, K.4
Emori, Y.5
-
147
-
-
0033611579
-
Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice
-
SWEETSER, D. A., G. J. FROELICK, A. M. MATSUMOTO, K. E. KAFER, B. MARCK et al., 1999 Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice. Oncogene 18: 877-886.
-
(1999)
Oncogene
, vol.18
, pp. 877-886
-
-
Sweetser, D.A.1
Froelick, G.J.2
Matsumoto, A.M.3
Kafer, K.E.4
Marck, B.5
-
148
-
-
0029736912
-
Regulation of cell-cell contacts in developing Drosophila eyes by Dsrc41, a new, close relative of vertebrate c-src
-
TAKAHASHI, F., S. ENDO, T. KOJIMA and K. SAIGO, 1996 Regulation of cell-cell contacts in developing Drosophila eyes by Dsrc41, a new, close relative of vertebrate c-src. Genes Dev. 10: 1645-1656.
-
(1996)
Genes Dev.
, vol.10
, pp. 1645-1656
-
-
Takahashi, F.1
Endo, S.2
Kojima, T.3
Saigo, K.4
-
149
-
-
0034849573
-
The GDNF/RET signaling pathway and human diseases
-
TAKAHASHI, M., 2001 The GDNF/RET signaling pathway and human diseases. Cytokine Growth Factor Rev. 12: 361-373.
-
(2001)
Cytokine Growth Factor Rev.
, vol.12
, pp. 361-373
-
-
Takahashi, M.1
-
150
-
-
0036499904
-
Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase
-
TANG, M. J., Y. CAI, S. J. TSAI, Y. K. WANG and G. R. DRESSLER, 2002 Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase. Dev. Biol. 243: 128-136.
-
(2002)
Dev. Biol.
, vol.243
, pp. 128-136
-
-
Tang, M.J.1
Cai, Y.2
Tsai, S.J.3
Wang, Y.K.4
Dressler, G.R.5
-
151
-
-
0037162714
-
Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
TAPON, N., K. F. HARVEY, D. W. BELL, D. C. WAHRER, T. A. SCHIRIPO et al., 2002 salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110: 467-478.
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
-
152
-
-
0032786441
-
Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system
-
TARAVIRAS, S., C. V. MARCOS-GUTIERREZ, P. DURBEC, H. JANI, M. GRIGORIOU et al., 1999 Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. Development 126: 2785-2797.
-
(1999)
Development
, vol.126
, pp. 2785-2797
-
-
Taraviras, S.1
Marcos-Gutierrez, C.V.2
Durbec, P.3
Jani, H.4
Grigoriou, M.5
-
153
-
-
0024319520
-
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
-
TAUTZ, D., and C. PFEIFLE, 1989 A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98: 81-85.
-
(1989)
Chromosoma
, vol.98
, pp. 81-85
-
-
Tautz, D.1
Pfeifle, C.2
-
154
-
-
0029584327
-
KSR, a novel protein kinase required for RAS signal transduction
-
THERRIEN, M., H. C. CHANG, N. M. SOLOMON, F. D. KARIM, D. A. WASSARMAN et al., 1995 KSR, a novel protein kinase required for RAS signal transduction. Cell 83: 879-888.
-
(1995)
Cell
, vol.83
, pp. 879-888
-
-
Therrien, M.1
Chang, H.C.2
Solomon, N.M.3
Karim, F.D.4
Wassarman, D.A.5
-
155
-
-
0032582663
-
CNK, a RAF-binding multidomain protein required for RAS signaling
-
THERRIEN, M., A. M. WONG and G. M. RUBIN, 1998 CNK, a RAF-binding multidomain protein required for RAS signaling. Cell 95: 343-353.
-
(1998)
Cell
, vol.95
, pp. 343-353
-
-
Therrien, M.1
Wong, A.M.2
Rubin, G.M.3
-
156
-
-
0033756219
-
A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila
-
THERRIEN, M.,D. K. MORRISON, A. M. WONG and G. M. RUBIN, 2000 A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila. Genetics 156: 1231-1242.
-
(2000)
Genetics
, vol.156
, pp. 1231-1242
-
-
Therrien, M.1
Morrison, D.K.2
Wong, A.M.3
Rubin, G.M.4
-
157
-
-
0029029343
-
Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines
-
TOH, Y., S. D. PENCIL and G. L. NICOLSON, 1995 Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines. Gene 159: 97-104.
-
(1995)
Gene
, vol.159
, pp. 97-104
-
-
Toh, Y.1
Pencil, S.D.2
Nicolson, G.L.3
-
158
-
-
0032578762
-
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
-
TONG, J. K., C. A. HASSIG, G. R. SCHNITZLER, R. E. KINGSTON and S. L. SCHREIBER, 1998 Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature 395: 917-921.
-
(1998)
Nature
, vol.395
, pp. 917-921
-
-
Tong, J.K.1
Hassig, C.A.2
Schnitzler, G.R.3
Kingston, R.E.4
Schreiber, S.L.5
-
159
-
-
0031579442
-
Misshapen encodes a protein kinase involved in cell shape control in Drosophila
-
TREISMAN, J. E., N. ITO and G. M. RUBIN, 1997 misshapen encodes a protein kinase involved in cell shape control in Drosophila. Gene 186: 119-125.
-
(1997)
Gene
, vol.186
, pp. 119-125
-
-
Treisman, J.E.1
Ito, N.2
Rubin, G.M.3
-
160
-
-
0037031590
-
An EGFR/Ebi/Sno pathway promotes delta expression by inactivating Su(H)/SMRTER repression during inductive notch signaling
-
TSUDA, L., R. NAGARAJ, S. L. ZIPURSKY and U. BANERJEE, 2002 An EGFR/Ebi/Sno pathway promotes delta expression by inactivating Su(H)/SMRTER repression during inductive notch signaling. Cell 110: 625-637.
-
(2002)
Cell
, vol.110
, pp. 625-637
-
-
Tsuda, L.1
Nagaraj, R.2
Zipursky, S.L.3
Banerjee, U.4
-
161
-
-
0037102238
-
A family of rhomboid intramembrane proteases activates all Drosophila membranetethered EGF ligands
-
URBAN, S., J. R. LEE and M. FREEMAN, 2002 A family of rhomboid intramembrane proteases activates all Drosophila membranetethered EGF ligands. EMBO J. 21: 4277-4286.
-
(2002)
EMBO J.
, vol.21
, pp. 4277-4286
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
162
-
-
0032936729
-
Predictive DNA testing for multiple endocrine neoplasia 2: A therapeutic challenge of prophylactic thyroidectomy in very young children
-
VAN HEURN, L. W., C. SCHAAP, G. SIE, A. A. HAAGEN, W. J. GERVER et al., 1999 Predictive DNA testing for multiple endocrine neoplasia 2: a therapeutic challenge of prophylactic thyroidectomy in very young children. J. Pediatr. Surg. 34: 568-571.
-
(1999)
J. Pediatr. Surg.
, vol.34
, pp. 568-571
-
-
Van Heurn, L.W.1
Schaap, C.2
Sie, G.3
Haagen, A.A.4
Gerver, W.J.5
-
163
-
-
0026332452
-
Induction in the developing compound eye of Drosophila: Multiple mechanisms restrict R7 induction to a single retinal precursor cell
-
VAN VACTOR, D. L., JR., R. L. CAGAN, H. KRAMER and S. L. ZIPURSKY, 1991 Induction in the developing compound eye of Drosophila: multiple mechanisms restrict R7 induction to a single retinal precursor cell. Cell 67: 1145-1155.
-
(1991)
Cell
, vol.67
, pp. 1145-1155
-
-
Van Vactor Jr., D.L.1
Cagan, R.L.2
Kramer, H.3
Zipursky, S.L.4
-
164
-
-
0029565750
-
Ret receptor tyrosine kinase activates extracellular signal-regulated kinase 2 in SK-N-MC cells
-
VAN WEERING, D. H., J. P. MEDEMA, A. VAN PUIJENBROEK, B. M. BURGERING, P. D. BAAS et al., 1995 Ret receptor tyrosine kinase activates extracellular signal-regulated kinase 2 in SK-N-MC cells. Oncogene 11: 2207-2214.
-
(1995)
Oncogene
, vol.11
, pp. 2207-2214
-
-
Van Weering, D.H.1
Medema, J.P.2
Van Puijenbroek, A.3
Burgering, B.M.4
Baas, P.D.5
-
165
-
-
0347417016
-
Signal integration during development: Insights from the Drosophila eye
-
VOAS, M. G., and I. REBAY, 2004 Signal integration during development: insights from the Drosophila eye. Dev. Dyn. 229: 162-175.
-
(2004)
Dev. Dyn.
, vol.229
, pp. 162-175
-
-
Voas, M.G.1
Rebay, I.2
-
166
-
-
0034520843
-
The C. elegans Mi-2 chromatinremodelling proteins function in vulval cell fate determination
-
VON ZELEWSKY, T., F. PALLADINO, K. BRUNSCHWIG, H. TOBLER, A. HAJNAL et al., 2000 The C. elegans Mi-2 chromatinremodelling proteins function in vulval cell fate determination. Development 127: 5277-5284.
-
(2000)
Development
, vol.127
, pp. 5277-5284
-
-
Von Zelewsky, T.1
Palladino, F.2
Brunschwig, K.3
Tobler, H.4
Hajnal, A.5
-
167
-
-
0015940314
-
C-cell hyperplasia preceding medullary thyroid carcinoma
-
WOLFE, H. J., K. E. MELVIN, S. J. CERVI-SKINNER, A. A. SAADI, J. F. JULIAR et al., 1973 C-cell hyperplasia preceding medullary thyroid carcinoma. N. Engl. J. Med. 289: 437-441.
-
(1973)
N. Engl. J. Med.
, vol.289
, pp. 437-441
-
-
Wolfe, H.J.1
Melvin, K.E.2
Cervi-Skinner, S.J.3
Saadi, A.A.4
Juliar, J.F.5
-
168
-
-
0025940103
-
Identification and characterization of a novel cytoskeleton-associated pp60src substrate
-
WU, H., A. B. REYNOLDS, S. B. KANNER, R. R. VINES and J. T. PARSONS, 1991 Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol. 11: 5113-5124.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 5113-5124
-
-
Wu, H.1
Reynolds, A.B.2
Kanner, S.B.3
Vines, R.R.4
Parsons, J.T.5
-
169
-
-
0028929414
-
Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene ncodes a putative protein kinase
-
XU, T., W. WANG, S. ZHANG, R. A. STEWART and W. YU, 1995 Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene ncodes a putative protein kinase. Development 121: 1053-1063.
-
(1995)
Development
, vol.121
, pp. 1053-1063
-
-
Xu, T.1
Wang, W.2
Zhang, S.3
Stewart, R.A.4
Yu, W.5
-
170
-
-
0032252209
-
NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
-
XUE, Y., J. WONG, G. T. MORENO, M. K. YOUNG, J. COTE et al., 1998 NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell 2: 851-861.
-
(1998)
Mol. Cell
, vol.2
, pp. 851-861
-
-
Xue, Y.1
Wong, J.2
Moreno, G.T.3
Young, M.K.4
Cote, J.5
-
171
-
-
18044403477
-
Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase
-
YAMASHITA, Y., S. KAJIGAYA, K. YOSHIDA, S. UENO, J. OTA et al., 2001 Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase. J. Biol. Chem. 276: 39012-39020.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39012-39020
-
-
Yamashita, Y.1
Kajigaya, S.2
Yoshida, K.3
Ueno, S.4
Ota, J.5
|