What goes up must come down: Molecular basis of MAPKAP kinase 2/3-dependent regulation of the inflammatory response and its inhibition

Biological Chemistry

Volumn 394, Issue 10, 2013, Pages 1301-1315

  Gaestel, Matthias ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Mitogen activated protein kinase activated protein kinase (MAPKAP); Mitogen activated protein kinase activated protein kinases 2 3 (MK2 3); Protein kinase inhibitor; Protein phosphorylation

Indexed keywords

2 (2 QUINOLIN 3 YLPYRIDIN 4 YL) 1,5,6,7 TETRAHYDRO 4H PYRROLO[3,2 C]PYRIDIN 4 ONE; 3 AMINOPYRAZOLE DERIVATIVE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 (4 CHLOROPHENYL) N [4 (PIPERAZIN 1 YL)PHENYL] 5 N (PYRIDINE 2 YMETHYL)FURAN 2 CARBAMIDE; BENZOTHIOPHENE; DIAMINOPYRIMIDINE; DSB PF 3644022; GLUTATHIONE TRANSFERASE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MMI 0100; N [3 [4 (3 BENZYL 1 ETHYL 5 PYRAZOLYL) 1 PIPERIDINYLMETHYL] 4 (3 FLUOROPHENYL)CYCLOPENTYL] N METHYLVALINE; PF 3644022; PHA 781089; PHYTOHEMAGGLUTININ; PYRAZOLOPYRIMIDINE; PYRROLOPYRIDINONE; PYRROLOPYRIMIDONE; SQUARIC ACID DIBUTYL ESTER; TRICYCLIC LACTAM; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ARTHRITIS; ASTHMA; AU RICH ELEMENT; CHRONIC INFLAMMATION; COMPETITIVE INHIBITION; DERMATITIS; DIARRHEA; DRUG STRUCTURE; ENTERITIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION; HEMOLYTIC UREMIC SYNDROME; HUMAN; IC 50; INFLAMMATION; INNATE IMMUNITY; LISTERIOSIS; LUPUS ERYTHEMATOSUS; MACROPHAGE; MALARIA; MALARIA FALCIPARUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PANCREATITIS; PHOSPHORYLATION; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN FUNCTION; PSORIASIS; RECEPTOR DOWN REGULATION; REVIEW; RHEUMATOID ARTHRITIS; RNA TRANSLATION; SARCOMA; TOXIC MEGACOLON; VASCULITIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; IMMUNITY, INNATE; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES;

EID: 84888108831     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2013-0197     Document Type: Review

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