-
1
-
-
34447339643
-
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
-
Wu JP, Wang J, Abeywardane A et al. (2007) The discovery of carboline analogs as potent MAPKAP-K2 inhibitors. Bioorg Med Chem Lett 17:4664-4669
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 4664-4669
-
-
Wu, J.P.1
Wang, J.2
Abeywardane, A.3
-
2
-
-
20044384349
-
Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)
-
Anderson DR, Hegde S, Reinhard E et al. (2005) Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2). Bioorg Med Chem Lett 15:1587-1590
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 1587-1590
-
-
Anderson, D.R.1
Hegde, S.2
Reinhard, E.3
-
3
-
-
34250181285
-
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)
-
Anderson DR, Meyers MJ, Vernier WF et al. (2007) Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). J Med Chem 50:2647-2654
-
(2007)
J Med Chem
, vol.50
, pp. 2647-2654
-
-
Anderson, D.R.1
Meyers, M.J.2
Vernier, W.F.3
-
4
-
-
0030426902
-
Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
-
Badger AM, Bradbeer JN, Votta B et al. (1996) Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther 279:1453-1461
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1453-1461
-
-
Badger, A.M.1
Bradbeer, J.N.2
Votta, B.3
-
5
-
-
27744522930
-
Potential adverse effects associated with inhibition of p38alpha/beta MAP kinases
-
Dambach DM (2005) Potential adverse effects associated with inhibition of p38alpha/beta MAP kinases. Curr Topics Med Chem 5:929-939
-
(2005)
Curr Topics Med Chem
, vol.5
, pp. 929-939
-
-
Dambach, D.M.1
-
6
-
-
66749134594
-
Targeting innate immunity protein kinase signalling in inflammation
-
Gaestel M, Kotlyarov A, Kracht M (2009) Targeting innate immunity protein kinase signalling in inflammation. Nat Rev Drug Discov 8:480-499
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 480-499
-
-
Gaestel, M.1
Kotlyarov, A.2
Kracht, M.3
-
7
-
-
34447258367
-
MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation
-
Gorska MM, Liang Q, Stafford SJ et al. (2007) MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation. J Exp Med 204:1637-1652
-
(2007)
J Exp Med
, vol.204
, pp. 1637-1652
-
-
Gorska, M.M.1
Liang, Q.2
Stafford, S.J.3
-
8
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
-
Kotlyarov A, Neininger A, Schubert C et al. (1999) MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat Cell Biol 1:94-97
-
(1999)
Nat Cell Biol
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
-
9
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon F, Tschopp J (2005) NLRs join TLRs as innate sensors of pathogens. Trends Immunol 26:447-454
-
(2005)
Trends Immunol
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
10
-
-
33845807361
-
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK
-
Ronkina N, Kotlyarov A, Dittrich-Breiholz O et al. (2007) The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. Mol Cell Biol 27:170-181
-
(2007)
Mol Cell Biol
, vol.27
, pp. 170-181
-
-
Ronkina, N.1
Kotlyarov, A.2
Dittrich-Breiholz, O.3
-
11
-
-
55549122292
-
Pyrrolo-pyrimidones: A novel class of MK2 inhibitors with potent cellular activity
-
Schlapbach A, Feifel R, Hawtin S et al. (2008) Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity. Bioorg Med Chem Lett 18:6142-6146
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 6142-6146
-
-
Schlapbach, A.1
Feifel, R.2
Hawtin, S.3
-
12
-
-
75549090082
-
The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-α pathway of systemic and cutaneous inflammation
-
Schottelius AJ, Zügel U, Döcke W-D et al. (2010) The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-α pathway of systemic and cutaneous inflammation. J Invest Dermatol 130:481-491
-
(2010)
J Invest Dermatol
, vol.130
, pp. 481-491
-
-
Schottelius, A.J.1
Zügel, U.2
Döcke, W.-D.3
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