-
1
-
-
60549083305
-
Inducible rodent models of acquired podocyte diseases
-
Pippin JW, Brinkkoetter PT, Cormack-Aboud FC, Durvasula RV, Hauser PV, et al. (2009) Inducible rodent models of acquired podocyte diseases. Am J Physiol Renal Physiol 296: F213-229.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
-
-
Pippin, J.W.1
Brinkkoetter, P.T.2
Cormack-Aboud, F.C.3
Durvasula, R.V.4
Hauser, P.V.5
-
2
-
-
0037269428
-
Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice
-
Yo Y, Braun MC, Barisoni L, Mobaraki H, Lu H, et al. (2003) Anti-mouse mesangial cell serum induces acute glomerulonephropathy in mice. Nephron Exp Nephrol 93: e92-106.
-
(2003)
Nephron Exp Nephrol
, vol.93
-
-
Yo, Y.1
Braun, M.C.2
Barisoni, L.3
Mobaraki, H.4
Lu, H.5
-
3
-
-
34547154349
-
p38 MAP-kinases pathway regulation, function and role in human diseases
-
Cuenda A, Rousseau S, (2007) p38 MAP-kinases pathway regulation, function and role in human diseases. Biochim Biophys Acta 1773: 1358-1375.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1358-1375
-
-
Cuenda, A.1
Rousseau, S.2
-
4
-
-
78049434471
-
MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin
-
Ronkina N, Menon MB, Schwermann J, Tiedje C, Hitti E, et al. (2010) MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin. Biochem Pharmacol 80: 1915-1920.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 1915-1920
-
-
Ronkina, N.1
Menon, M.B.2
Schwermann, J.3
Tiedje, C.4
Hitti, E.5
-
5
-
-
35348907987
-
Protein kinases as small molecule inhibitor targets in inflammation
-
Gaestel M, Mengel A, Bothe U, Asadullah K, (2007) Protein kinases as small molecule inhibitor targets in inflammation. Curr Med Chem 14: 2214-2234.
-
(2007)
Curr Med Chem
, vol.14
, pp. 2214-2234
-
-
Gaestel, M.1
Mengel, A.2
Bothe, U.3
Asadullah, K.4
-
6
-
-
33845807361
-
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK
-
Ronkina N, Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, et al. (2007) The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK. Mol Cell Biol 27: 170-181.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 170-181
-
-
Ronkina, N.1
Kotlyarov, A.2
Dittrich-Breiholz, O.3
Kracht, M.4
Hitti, E.5
-
7
-
-
30344475768
-
Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome
-
Koshikawa M, Mukoyama M, Mori K, Suganami T, Sawai K, et al. (2005) Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J Am Soc Nephrol 16: 2690-2701.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2690-2701
-
-
Koshikawa, M.1
Mukoyama, M.2
Mori, K.3
Suganami, T.4
Sawai, K.5
-
8
-
-
34047205066
-
Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6
-
Sheryanna A, Bhangal G, McDaid J, Smith J, Manning A, et al. (2007) Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6. J Am Soc Nephrol 18: 1167-1179.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1167-1179
-
-
Sheryanna, A.1
Bhangal, G.2
McDaid, J.3
Smith, J.4
Manning, A.5
-
9
-
-
42449162927
-
Selective p38MAPK isoform expression and activation in antineutrophil cytoplasmatic antibody-associated crescentic glomerulonephritis: role of p38MAPKalpha
-
Polzer K, Soleiman A, Baum W, Axmann R, Distler J, et al. (2008) Selective p38MAPK isoform expression and activation in antineutrophil cytoplasmatic antibody-associated crescentic glomerulonephritis: role of p38MAPKalpha. Ann Rheum Dis 67: 602-608.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 602-608
-
-
Polzer, K.1
Soleiman, A.2
Baum, W.3
Axmann, R.4
Distler, J.5
-
10
-
-
0344945470
-
Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis
-
Stambe C, Atkins RC, Hill PA, Nikolic-Paterson DJ, (2003) Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis. Kidney Int 64: 2121-2132.
-
(2003)
Kidney Int
, vol.64
, pp. 2121-2132
-
-
Stambe, C.1
Atkins, R.C.2
Hill, P.A.3
Nikolic-Paterson, D.J.4
-
11
-
-
0037307476
-
Blockade of p38alpha MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis
-
Stambe C, Atkins RC, Tesch GH, Kapoun AM, Hill PA, et al. (2003) Blockade of p38alpha MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis. J Am Soc Nephrol 14: 338-351.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 338-351
-
-
Stambe, C.1
Atkins, R.C.2
Tesch, G.H.3
Kapoun, A.M.4
Hill, P.A.5
-
12
-
-
0942298030
-
p38 Mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: correlation with renal injury
-
Stambe C, Nikolic-Paterson DJ, Hill PA, Dowling J, Atkins RC, (2004) p38 Mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: correlation with renal injury. J Am Soc Nephrol 15: 326-336.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 326-336
-
-
Stambe, C.1
Nikolic-Paterson, D.J.2
Hill, P.A.3
Dowling, J.4
Atkins, R.C.5
-
13
-
-
80052009791
-
Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury
-
Pengal R, Guess AJ, Agrawal S, Manley J, Ransom RF, et al. (2011) Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury. Am J Physiol Renal Physiol 301: F509-519.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
-
-
Pengal, R.1
Guess, A.J.2
Agrawal, S.3
Manley, J.4
Ransom, R.F.5
-
15
-
-
33244471768
-
MAPKAP kinases - MKs - two's company, three's a crowd
-
Gaestel M, (2006) MAPKAP kinases- MKs- two's company, three's a crowd. Nat Rev Mol Cell Biol 7: 120-130.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 120-130
-
-
Gaestel, M.1
-
16
-
-
79960027929
-
Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3
-
Ehlting C, Ronkina N, Bohmer O, Albrecht U, Bode KA, et al. (2011) Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3. J Biol Chem 286: 24113-24124.
-
(2011)
J Biol Chem
, vol.286
, pp. 24113-24124
-
-
Ehlting, C.1
Ronkina, N.2
Bohmer, O.3
Albrecht, U.4
Bode, K.A.5
-
17
-
-
52049108016
-
Specificity of signaling from MAPKs to MAPKAPKs: kinases' tango nuevo
-
Gaestel M, (2008) Specificity of signaling from MAPKs to MAPKAPKs: kinases' tango nuevo. Front Biosci 13: 6050-6059.
-
(2008)
Front Biosci
, vol.13
, pp. 6050-6059
-
-
Gaestel, M.1
-
18
-
-
0026342759
-
Identification of the phosphorylation sites of the murine small heat shock protein hsp25
-
Gaestel M, Schroder W, Benndorf R, Lippmann C, Buchner K, et al. (1991) Identification of the phosphorylation sites of the murine small heat shock protein hsp25. J Biol Chem 266: 14721-14724.
-
(1991)
J Biol Chem
, vol.266
, pp. 14721-14724
-
-
Gaestel, M.1
Schroder, W.2
Benndorf, R.3
Lippmann, C.4
Buchner, K.5
-
19
-
-
0030565457
-
A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress
-
Clifton AD, Young PR, Cohen P, (1996) A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress. FEBS Lett 392: 209-214.
-
(1996)
FEBS Lett
, vol.392
, pp. 209-214
-
-
Clifton, A.D.1
Young, P.R.2
Cohen, P.3
-
20
-
-
77953021835
-
Mitogen-activated protein kinase p38 and MK2, MK3 and MK5: menage a trois or menage a quatre?
-
Shiryaev A, Moens U, (2010) Mitogen-activated protein kinase p38 and MK2, MK3 and MK5: menage a trois or menage a quatre? Cell Signal 22: 1185-1192.
-
(2010)
Cell Signal
, vol.22
, pp. 1185-1192
-
-
Shiryaev, A.1
Moens, U.2
-
21
-
-
79955923760
-
Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation
-
Shiryaev A, Dumitriu G, Moens U, (2011) Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation. J Mol Signal 6: 4.
-
(2011)
J Mol Signal
, vol.6
, pp. 4
-
-
Shiryaev, A.1
Dumitriu, G.2
Moens, U.3
-
22
-
-
0033983567
-
Ischemic acute renal failure induces differential expression of small heat shock proteins
-
Smoyer WE, Ransom R, Harris RC, Welsh MJ, Lutsch G, et al. (2000) Ischemic acute renal failure induces differential expression of small heat shock proteins. J Am Soc Nephrol 11: 211-221.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 211-221
-
-
Smoyer, W.E.1
Ransom, R.2
Harris, R.C.3
Welsh, M.J.4
Lutsch, G.5
-
23
-
-
0036183944
-
Hsp27 regulates podocyte cytoskeletal changes in an in vitro model of podocyte process retraction
-
Smoyer WE, Ransom RF, (2002) Hsp27 regulates podocyte cytoskeletal changes in an in vitro model of podocyte process retraction. FASEB J 16: 315-326.
-
(2002)
FASEB J
, vol.16
, pp. 315-326
-
-
Smoyer, W.E.1
Ransom, R.F.2
-
24
-
-
18744394644
-
p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli
-
Hirano S, Sun X, DeGuzman CA, Ransom RF, McLeish KR, et al. (2005) p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli. Am J Physiol Renal Physiol 288: F1133-1143.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
-
-
Hirano, S.1
Sun, X.2
DeGuzman, C.A.3
Ransom, R.F.4
McLeish, K.R.5
-
25
-
-
84855221098
-
HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II
-
Sanchez-Nino MD, Sanz AB, Sanchez-Lopez E, Ruiz-Ortega M, Benito-Martin A, et al. (2012) HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II. Lab Invest 92: 32-45.
-
(2012)
Lab Invest
, vol.92
, pp. 32-45
-
-
Sanchez-Nino, M.D.1
Sanz, A.B.2
Sanchez-Lopez, E.3
Ruiz-Ortega, M.4
Benito-Martin, A.5
-
26
-
-
33646010643
-
Chaperones in preventing protein denaturation in living cells and protecting against cellular stress
-
Kampinga HH, (2006) Chaperones in preventing protein denaturation in living cells and protecting against cellular stress. Handb Exp Pharmacol pp. 1-42.
-
(2006)
Handb Exp Pharmacol
, pp. 1-42
-
-
Kampinga, H.H.1
-
27
-
-
61549108620
-
Up regulation of the GRP-78 and GADD-153 and down regulation of Bcl-2 proteins in primary glomerular diseases: a possible involvement of the ER stress pathway in glomerulonephritis
-
Markan S, Kohli HS, Joshi K, Minz RW, Sud K, et al. (2009) Up regulation of the GRP-78 and GADD-153 and down regulation of Bcl-2 proteins in primary glomerular diseases: a possible involvement of the ER stress pathway in glomerulonephritis. Mol Cell Biochem 324: 131-138.
-
(2009)
Mol Cell Biochem
, vol.324
, pp. 131-138
-
-
Markan, S.1
Kohli, H.S.2
Joshi, K.3
Minz, R.W.4
Sud, K.5
-
28
-
-
84858773146
-
Podocyte Injury Associated with Mutant alpha-Actinin-4
-
Cybulsky AV, Kennedy CR, (2011) Podocyte Injury Associated with Mutant alpha-Actinin-4. J Signal Transduct 2011: 563128.
-
(2011)
J Signal Transduct
, vol.2011
, pp. 563128
-
-
Cybulsky, A.V.1
Kennedy, C.R.2
-
29
-
-
80155151897
-
mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome
-
Ito N, Nishibori Y, Ito Y, Takagi H, Akimoto Y, et al. (2011) mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome. Lab Invest 91: 1584-1595.
-
(2011)
Lab Invest
, vol.91
, pp. 1584-1595
-
-
Ito, N.1
Nishibori, Y.2
Ito, Y.3
Takagi, H.4
Akimoto, Y.5
-
30
-
-
0018610784
-
New micro-turbidimetric method for determination of protein in cerebrospinal fluid and urine
-
Iwata J, Nishikaze O, (1979) New micro-turbidimetric method for determination of protein in cerebrospinal fluid and urine. Clin Chem 25: 1317-1319.
-
(1979)
Clin Chem
, vol.25
, pp. 1317-1319
-
-
Iwata, J.1
Nishikaze, O.2
-
31
-
-
41849125275
-
Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue
-
Robertson D, Savage K, Reis-Filho JS, Isacke CM, (2008) Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue. BMC Cell Biol 9: 13.
-
(2008)
BMC Cell Biol
, vol.9
, pp. 13
-
-
Robertson, D.1
Savage, K.2
Reis-Filho, J.S.3
Isacke, C.M.4
-
33
-
-
42549105123
-
Podocyte injury induced by albumin overload in vivo and in vitro: involvement of TGF-beta and p38 MAPK
-
Yoshida S, Nagase M, Shibata S, Fujita T, (2008) Podocyte injury induced by albumin overload in vivo and in vitro: involvement of TGF-beta and p38 MAPK. Nephron Exp Nephrol 108: e57-68.
-
(2008)
Nephron Exp Nephrol
, vol.108
-
-
Yoshida, S.1
Nagase, M.2
Shibata, S.3
Fujita, T.4
-
34
-
-
44449177614
-
Deletion of MK2 signalling in vivo inhibits small Hsp phosphorylation but not diabetic nephropathy
-
Park JK, Ronkina N, Hoft A, Prohl C, Menne J, et al. (2008) Deletion of MK2 signalling in vivo inhibits small Hsp phosphorylation but not diabetic nephropathy. Nephrol Dial Transplant 23: 1844-1853.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1844-1853
-
-
Park, J.K.1
Ronkina, N.2
Hoft, A.3
Prohl, C.4
Menne, J.5
-
35
-
-
21344446946
-
Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria
-
Yu D, Petermann A, Kunter U, Rong S, Shankland SJ, et al. (2005) Urinary podocyte loss is a more specific marker of ongoing glomerular damage than proteinuria. J Am Soc Nephrol 16: 1733-1741.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1733-1741
-
-
Yu, D.1
Petermann, A.2
Kunter, U.3
Rong, S.4
Shankland, S.J.5
-
36
-
-
16244415855
-
R-roscovitine (CYC202) alleviates renal cell proliferation in nephritis without aggravating podocyte injury
-
Milovanceva-Popovska M, Kunter U, Ostendorf T, Petermann A, Rong S, et al. (2005) R-roscovitine (CYC202) alleviates renal cell proliferation in nephritis without aggravating podocyte injury. Kidney Int 67: 1362-1370.
-
(2005)
Kidney Int
, vol.67
, pp. 1362-1370
-
-
Milovanceva-Popovska, M.1
Kunter, U.2
Ostendorf, T.3
Petermann, A.4
Rong, S.5
-
37
-
-
80052515579
-
Heat shock proteins in chronic kidney disease
-
Musial K, Zwolinska D, (2011) Heat shock proteins in chronic kidney disease. Pediatr Nephrol 26: 1031-1037.
-
(2011)
Pediatr Nephrol
, vol.26
, pp. 1031-1037
-
-
Musial, K.1
Zwolinska, D.2
-
38
-
-
0032924098
-
Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney
-
Dousa TP, (1999) Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney. Kidney Int 55: 29-62.
-
(1999)
Kidney Int
, vol.55
, pp. 29-62
-
-
Dousa, T.P.1
-
39
-
-
34250181285
-
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)
-
Anderson DR, Meyers MJ, Vernier WF, Mahoney MW, Kurumbail RG, et al. (2007) Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). J Med Chem 50: 2647-2654.
-
(2007)
J Med Chem
, vol.50
, pp. 2647-2654
-
-
Anderson, D.R.1
Meyers, M.J.2
Vernier, W.F.3
Mahoney, M.W.4
Kurumbail, R.G.5
-
40
-
-
0030894683
-
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
-
Han J, Jiang Y, Li Z, Kravchenko VV, Ulevitch RJ, (1997) Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 386: 296-299.
-
(1997)
Nature
, vol.386
, pp. 296-299
-
-
Han, J.1
Jiang, Y.2
Li, Z.3
Kravchenko, V.V.4
Ulevitch, R.J.5
-
41
-
-
77955654604
-
Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function
-
Murea M, Park JK, Sharma S, Kato H, Gruenwald A, et al. (2010) Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function. Kidney Int 78: 514-522.
-
(2010)
Kidney Int
, vol.78
, pp. 514-522
-
-
Murea, M.1
Park, J.K.2
Sharma, S.3
Kato, H.4
Gruenwald, A.5
-
42
-
-
3242749031
-
Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice
-
Menne J, Park JK, Boehne M, Elger M, Lindschau C, et al. (2004) Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice. Diabetes 53: 2101-2109.
-
(2004)
Diabetes
, vol.53
, pp. 2101-2109
-
-
Menne, J.1
Park, J.K.2
Boehne, M.3
Elger, M.4
Lindschau, C.5
-
43
-
-
79951674629
-
mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression
-
Huber TB, Walz G, Kuehn EW, (2011) mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression. Kidney Int 79: 502-511.
-
(2011)
Kidney Int
, vol.79
, pp. 502-511
-
-
Huber, T.B.1
Walz, G.2
Kuehn, E.W.3
|