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Volumn 31, Issue 8, 2011, Pages 629-637

Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3′ untranslated region

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 80051499526     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2010.0154     Document Type: Article
Times cited : (88)

References (43)
  • 1
    • 47149104071 scopus 로고    scopus 로고
    • The blockade of IL-6 signaling in rational drug design
    • DOI 10.2174/138161208784246072
    • Adachi Y, Yoshio-Hoshino N, Nishimoto N. 2008. The blockade of IL-6 signaling in rational drug design. Curr Pharm Des 14(12):1217-1224. (Pubitemid 351997834)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.12 , pp. 1217-1224
    • Adachi, Y.1    Yoshio-Hoshino, N.2    Nishimoto, N.3
  • 2
    • 0037252788 scopus 로고    scopus 로고
    • ARED 2.0: An update of AU-rich element mRNA database
    • DOI 10.1093/nar/gkg023
    • Bakheet T, Williams BR, Khabar KS. 2003. ARED 2.0: An update of AU-rich element mRNA database. Nucleic Acids Res 31(1):421-423. (Pubitemid 36150418)
    • (2003) Nucleic Acids Research , vol.31 , Issue.1 , pp. 421-423
    • Bakheet, T.1    Williams, B.R.G.2    Khabar, K.S.A.3
  • 3
    • 0035834741 scopus 로고    scopus 로고
    • Decreased sensitivity of tristetraprolindeficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway
    • Carballo E, Cao H, Lai WS, Kennington EA, Campbell D, Blackshear PJ. 2001. Decreased sensitivity of tristetraprolindeficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway. J Biol Chem 276(45):42580-42587.
    • (2001) J Biol Chem , vol.276 , Issue.45 , pp. 42580-42587
    • Carballo, E.1    Cao, H.2    Lai, W.S.3    Kennington, E.A.4    Campbell, D.5    Blackshear, P.J.6
  • 4
    • 0032516626 scopus 로고    scopus 로고
    • Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin
    • Carballo E, Lai WS, Blackshear PJ. 1998. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science 281(5379):1001-1005. (Pubitemid 28399252)
    • (1998) Science , vol.281 , Issue.5379 , pp. 1001-1005
    • Carballo, E.1    Lai, W.S.2    Blackshear, P.J.3
  • 5
    • 0034653560 scopus 로고    scopus 로고
    • Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability
    • Carballo E, Lai WS, Blackshear PJ. 2000. Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability. Blood 95(6):1891-1899. (Pubitemid 30151623)
    • (2000) Blood , vol.95 , Issue.6 , pp. 1891-1899
    • Carballo, E.1    Lai, W.S.2    Blackshear, P.J.3
  • 7
    • 0035094047 scopus 로고    scopus 로고
    • Serum levels of interleukin 6 and stress related substances indicate mental stress condition in patients with rheumatoid arthritis
    • Hirano D, Nagashima M, Ogawa R, Yoshino S. 2001. Serum levels of interleukin 6 and stress related substances indicate mental stress condition in patients with rheumatoid arthritis. J Rheumatol 28(3):490-495. (Pubitemid 32202648)
    • (2001) Journal of Rheumatology , vol.28 , Issue.3 , pp. 490-495
    • Hirano, D.1    Nagashima, M.2    Ogawa, R.3    Yoshino, S.4
  • 8
    • 0036266114 scopus 로고    scopus 로고
    • Bacteria induce osteoclastogenesis via an osteoblast-independent pathway
    • DOI 10.1128/IAI.70.6.3143-3148.2002
    • Jiang Y, Mehta CK, Hsu TY, Alsulaimani FF. 2002. Bacteria induce osteoclastogenesis via an osteoblast-independent pathway. Infect Immun 70(6):3143-3148. (Pubitemid 34564177)
    • (2002) Infection and Immunity , vol.70 , Issue.6 , pp. 3143-3148
    • Jiang, Y.1    Mehta, C.K.2    Hsu, T.-Y.3    Alsulaimani, F.F.H.4
  • 9
    • 0037124067 scopus 로고    scopus 로고
    • Cytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanisms
    • DOI 10.1074/jbc.M110465200
    • Johnson BA, Stehn JR, Yaffe MB, Blackwell TK. 2002. Cytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanisms. J Biol Chem 277(20):18029-18036. (Pubitemid 34967615)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.20 , pp. 18029-18036
    • Johnson, B.A.1    Stehn, J.R.2    Yaffe, M.B.3    Keith Blackwell, T.4
  • 11
    • 0035498663 scopus 로고    scopus 로고
    • Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma
    • DOI 10.1002/1097-0142(20011101)92:9<2399::AID-CNCR1588>3.0.CO;2-W
    • Kasuga I, Makino S, Kiyokawa H, Katoh H, Ebihara Y, Ohyashiki K. 2001. Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma. Cancer 92(9):2399-2405. (Pubitemid 33029085)
    • (2001) Cancer , vol.92 , Issue.9 , pp. 2399-2405
    • Kasuga, I.1    Makino, S.2    Kiyokawa, H.3    Katoh, H.4    Ebihara, Y.5    Ohyashiki, K.6
  • 12
    • 12144251356 scopus 로고    scopus 로고
    • The AU-rich transcriptome: More than interferons and cytokines, and its role in disease
    • Khabar KS. 2005. The AU-rich transcriptome: More than interferons and cytokines, and its role in disease. J Interferon Cytokine Res 25(1):1-10. (Pubitemid 40105586)
    • (2005) Journal of Interferon and Cytokine Research , vol.25 , Issue.1 , pp. 1-10
    • Khabar, K.S.A.1
  • 13
    • 34249699555 scopus 로고    scopus 로고
    • Rapid transit in the immune cells: The role of mRNA turnover regulation
    • DOI 10.1189/jlb.0207109
    • Khabar KS. 2007. Rapid transit in the immune cells: The role of mRNA turnover regulation. J Leukoc Biol 81(6):1335-1344. (Pubitemid 46827957)
    • (2007) Journal of Leukocyte Biology , vol.81 , Issue.6 , pp. 1335-1344
    • Khabar, K.S.A.1
  • 14
    • 77956727472 scopus 로고    scopus 로고
    • Post-transcriptional control during chronic inflammation and cancer: A focus on AU-rich elements
    • Khabar KS. 2010. Post-transcriptional control during chronic inflammation and cancer: A focus on AU-rich elements. Cell Mol Life Sci 67(17):2937-2955.
    • (2010) Cell Mol Life Sci , vol.67 , Issue.17 , pp. 2937-2955
    • Khabar, K.S.1
  • 15
    • 12844271570 scopus 로고    scopus 로고
    • AU-rich transient response transcripts in the human genome: Expressed sequence tag clustering and gene discovery approach
    • DOI 10.1016/j.ygeno.2004.10.004, PII S0888754304002782
    • Khabar KS, Bakheet T, Williams BR. 2005. AU-rich transient response transcripts in the human genome: expressed sequence tag clustering and gene discovery approach. Genomics 85(2):165-175. (Pubitemid 40164782)
    • (2005) Genomics , vol.85 , Issue.2 , pp. 165-175
    • Khabar, K.S.A.1    Bakheet, T.2    Williams, B.R.G.3
  • 17
    • 0036863319 scopus 로고    scopus 로고
    • Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?
    • DOI 10.1042/BST0300959
    • Kotlyarov A, Gaestel M. 2002. Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression? Biochem Soc Trans 30(Pt 6):959-963. (Pubitemid 36002388)
    • (2002) Biochemical Society Transactions , vol.30 , Issue.6 , pp. 959-963
    • Kotlyarov, A.1    Gaestel, M.2
  • 18
    • 0033049125 scopus 로고    scopus 로고
    • Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
    • Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear PJ. 1999. Evidence that tristetraprolin binds to AUrich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol 19(6):4311-4323. (Pubitemid 29242006)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.6 , pp. 4311-4323
    • Lai, W.I.S.1    Carballo, E.2    Strum, J.R.3    Kennington, E.A.4    Phillips, R.S.5    Blackshear, P.J.6
  • 20
    • 13244298460 scopus 로고    scopus 로고
    • Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1
    • DOI 10.1101/gad.1282305
    • Lykke-Andersen J, Wagner E. 2005. Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. Genes Dev 19(3):351-361. (Pubitemid 40189298)
    • (2005) Genes and Development , vol.19 , Issue.3 , pp. 351-361
    • Lykke-Andersen, J.1    Wagner, E.2
  • 21
    • 0034816062 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability
    • DOI 10.1128/MCB.21.9.6461-6469.2001
    • Mahtani KR, Brook M, Dean JL, Sully G, Saklatvala J, Clark AR. 2001. Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol Cell Biol 21(19):6461-6469. (Pubitemid 32927414)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.19 , pp. 6461-6469
    • Mahtani, K.R.1    Brook, M.2    Dean, J.L.E.3    Sully, G.4    Saklatvala, J.5    Clark, A.R.6
  • 22
    • 77949875590 scopus 로고    scopus 로고
    • Interleukin-6 as a therapeutic target in candidate inflammatory diseases
    • Nishimoto N. 2010. Interleukin-6 as a therapeutic target in candidate inflammatory diseases. Clin Pharmacol Ther 87(4):483-487.
    • (2010) Clin Pharmacol Ther , vol.87 , Issue.4 , pp. 483-487
    • Nishimoto, N.1
  • 23
    • 33750328512 scopus 로고    scopus 로고
    • A. actinomycetemcomitans LPS induces IL-6 expression through multiple MAPK pathways in periodontal ligament fibroblasts
    • Patil C, Rossa C, Jr., Kirkwood KL. 2006. A. actinomycetemcomitans LPS induces IL-6 expression through multiple MAPK pathways in periodontal ligament fibroblasts. Oral Microbiol Immunol 21(6):392-398.
    • (2006) Oral Microbiol Immunol , vol.21 , Issue.6 , pp. 392-398
    • Patil, C.1    Rossa Jr., C.2    Kirkwood, K.L.3
  • 24
    • 2542469918 scopus 로고    scopus 로고
    • P38 MAPK regulates IL-1β induced IL-6 expression through mRNA stability in osteoblasts
    • Patil C, Zhu X, Rossa C, Jr., Kim YJ, Kirkwood KL. 2004. p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts. Immunol Invest 33(2):213-233. (Pubitemid 38685932)
    • (2004) Immunological Investigations , vol.33 , Issue.2 , pp. 213-233
    • Patil, C.1    Zhu, X.2    Rossa Jr., C.3    Kim, Y.J.4    Kirkwood, K.L.5
  • 25
    • 34548762586 scopus 로고    scopus 로고
    • P38 MAPK signaling in oral-related diseases
    • Patil CS, Kirkwood KL. 2007. p38 MAPK signaling in oral-related diseases. J Dent Res 86(9):812-825.
    • (2007) J Dent Res , vol.86 , Issue.9 , pp. 812-825
    • Patil, C.S.1    Kirkwood, K.L.2
  • 27
    • 2542596992 scopus 로고    scopus 로고
    • Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference
    • DOI 10.1093/nar/gkh282
    • Raineri I, Wegmueller D, Gross B, Certa U, Moroni C. 2004. Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res 32(4):1279-1288. (Pubitemid 38854729)
    • (2004) Nucleic Acids Research , vol.32 , Issue.4 , pp. 1279-1288
    • Raineri, I.1    Wegmueller, D.2    Gross, B.3    Certa, U.4    Moroni, C.5
  • 28
    • 20444414937 scopus 로고    scopus 로고
    • Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function
    • Rigby WF, Roy K, Collins J, Rigby S, Connolly JE, Bloch DB, Brooks SA. 2005. Structure/function analysis of tristetraprolin (TTP): P38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function. J Immunol 174(12):7883-7893. (Pubitemid 40806298)
    • (2005) Journal of Immunology , vol.174 , Issue.12 , pp. 7883-7893
    • Rigby, W.F.C.1    Roy, K.2    Collins, J.3    Rigby, S.4    Connolly, J.E.5    Bloch, D.B.6    Brooks, S.A.7
  • 29
    • 33750600353 scopus 로고    scopus 로고
    • MKK3/6-p38 MAPK signaling is required for IL-1β and TNF-α-induced RANKL expression in bone marrow stromal cells
    • DOI 10.1089/jir.2006.26.719
    • Rossa C, Jr., Ehman K, Liu M, Patil C, Kirkwood K. 2006. MKK3/6-p38MAPK signaling is required for IL-1b And TNF-a induced RANKL expression in bone marrow stromal cells. J Interferon Cytokine Res 26(10):719-729. (Pubitemid 44934111)
    • (2006) Journal of Interferon and Cytokine Research , vol.26 , Issue.10 , pp. 719-729
    • Rossa Jr., C.1    Ehmann, K.2    Liu, M.3    Patil, C.4    Kirkwood, K.L.5
  • 30
    • 39749196423 scopus 로고    scopus 로고
    • A dominant function of p38 mitogen-activated protein kinase signaling in receptor activator of nuclear factor-kappaB ligand expression and osteoclastogenesis induction by Aggregatibacter actinomycetemcomitans and Escherichia coli lipopolysaccharide
    • Rossa C, Jr., Liu M, Kirkwood KL. 2008. A dominant function of p38 mitogen-activated protein kinase signaling in receptor activator of nuclear factor-kappaB ligand expression and osteoclastogenesis induction by Aggregatibacter actinomycetemcomitans and Escherichia coli lipopolysaccharide. J Periodontal Res 43(2):201-211.
    • (2008) J Periodontal Res , vol.43 , Issue.2 , pp. 201-211
    • Rossa Jr., C.1    Liu, M.2    Kirkwood, K.L.3
  • 31
    • 45249098952 scopus 로고    scopus 로고
    • Control of mRNA decay by phosphorylation of tristetraprolin
    • DOI 10.1042/BST0360491
    • Sandler H, Stoecklin G. 2008. Control of mRNA decay by phosphorylation of tristetraprolin. Biochem Soc Trans 36(Pt 3): 491-496. (Pubitemid 351839361)
    • (2008) Biochemical Society Transactions , vol.36 , Issue.3 , pp. 491-496
    • Sandler, H.1    Stoecklin, G.2
  • 33
    • 0038798677 scopus 로고    scopus 로고
    • A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA
    • DOI 10.1038/sj.onc.1206418
    • Stoecklin G, Gross B, Ming XF, Moroni C. 2003. A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA. Oncogene 22(23):3554-3561. (Pubitemid 36765315)
    • (2003) Oncogene , vol.22 , Issue.23 , pp. 3554-3561
    • Stoecklin, G.1    Gross, B.2    Ming, X.-F.3    Moroni, C.4
  • 34
    • 1942471656 scopus 로고    scopus 로고
    • MK2-induced tristetraprolin:14-3-3 Complexes prevent stress granule association and ARE-mRNA decay
    • DOI 10.1038/sj.emboj.7600163
    • Stoecklin G, Stubbs T, Kedersha N, Wax S, Rigby WF, Blackwell TK, Anderson P. 2004. MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J 23(6):1313-1324. (Pubitemid 38525003)
    • (2004) EMBO Journal , vol.23 , Issue.6 , pp. 1313-1324
    • Stoecklin, G.1    Stubbs, T.2    Kedersha, N.3    Wax, S.4    Rigby, W.F.C.5    Blackwell, T.K.6    Anderson, P.7
  • 35
    • 1242337338 scopus 로고    scopus 로고
    • Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: Evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1)
    • Sully G, Dean JL, Wait R, Rawlinson L, Santalucia T, Saklatvala J, Clark AR. 2004. Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/ poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-elementbinding protein 1). Biochem J 377(Pt 3):629-639. (Pubitemid 38221834)
    • (2004) Biochemical Journal , vol.377 , Issue.3 , pp. 629-639
    • Sully, G.1    Dean, J.L.E.2    Wait, R.3    Rawlinson, L.4    Santalucia, T.5    Saklatvala, J.6    Clark, A.R.7
  • 38
    • 0026031875 scopus 로고
    • The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat
    • Varnum BC, Ma QF, Chi TH, Fletcher B, Herschman HR. 1991. The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat. Mol Cell Biol 11(3):1754-1758. (Pubitemid 21895539)
    • (1991) Molecular and Cellular Biology , vol.11 , Issue.3 , pp. 1754-1758
    • Varnum, B.C.1    Ma, Q.2    Chi, T.3    Fletcher, B.4    Herschman, H.R.5
  • 40
    • 0033568608 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • DOI 10.1093/emboj/18.18.4969
    • Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Muller M, Gaestel M, Resch K, Holtmann H. 1999. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J 18(18):4969-4980. (Pubitemid 29443799)
    • (1999) EMBO Journal , vol.18 , Issue.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3    Wilhelm, A.4    Chen, C.-Y.A.5    Shyu, A.-B.6    Muller, M.7    Gaestel, M.8    Resch, K.9    Holtmann, H.10
  • 41
    • 33847084044 scopus 로고    scopus 로고
    • Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor
    • Yoshio-Hoshino N, Adachi Y, Aoki C, Pereboev A, Curiel DT, Nishimoto N. 2007. Establishment of a new interleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumor. Cancer Res 67(3):871-875.
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 871-875
    • Yoshio-Hoshino, N.1    Adachi, Y.2    Aoki, C.3    Pereboev, A.4    Curiel, D.T.5    Nishimoto, N.6
  • 42
    • 38349114778 scopus 로고    scopus 로고
    • P38alpha stabilizes interleukin-6 mRNA via multiple AU-rich elements
    • Zhao W, Liu M, Kirkwood KL. 2008. p38alpha stabilizes interleukin-6 mRNA via multiple AU-rich elements. J Biol Chem 283(4):1778-1785.
    • (2008) J Biol Chem , vol.283 , Issue.4 , pp. 1778-1785
    • Zhao, W.1    Liu, M.2    Kirkwood, K.L.3


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