Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 1435-1446

  Taheripak, Gholamreza ^a   Bakhtiyari, Salar ^b   Rajabibazl, Masoumeh ^c   Pasalar, Parvin ^a   Meshkani, Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ILAM UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Apoptosis; Free radicals; Mitochondrial dysfunction; Palmitate; PTP1B

Indexed keywords

CASPASE 3; CASPASE 9; CERAMIDE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN TYROSINE PHOSPHATASE 1B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR RELA;

APOPTOSIS; ARTICLE; BIOGENESIS; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; MITOCHONDRION; MUSCLE CELL; MYOTUBE; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE;

APOPTOSIS; C-JUN N-TERMINAL KINASE; FFA; FORKHEAD BOX PROTEIN O1; FOXO-1; FREE FATTY ACID; FREE RADICALS; JNK; MITOCHONDRIAL DYSFUNCTION; NF-ΚB; NUCLEAR FACTOR-ΚB; PALMITATE; PROTEIN TYROSINE PHOSPHATASE 1B; PTP1B; REACTIVE OXYGEN SPECIES; ROS; SERINE-PALMITOYL-COA TRANSFERASE; SPT; TERMINAL DEOXYNUCLEOTIDE TRANSFERASE DUTP NICK-END LABELING; TUNEL;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOSINE TRIPHOSPHATE; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE; CELL SURVIVAL; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; NUCLEAR RESPIRATORY FACTOR 1; PALMITATES; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SIRTUIN 1; SPHINGOSINE; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS;

EID: 84887976536     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.09.019     Document Type: Article

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