-
1
-
-
78649660058
-
Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: Role of oxidative stress
-
Yuzefovych L, Wilson G, Rachek L 2010 Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am J Physiol Endocrinol Metab 299:E1096-E1105
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
Yuzefovych, L.1
Wilson, G.2
Rachek, L.3
-
2
-
-
0037160132
-
Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria
-
DOI 10.1074/jbc.M208770200
-
Rachek LI, Grishko VI, Musiyenko SI, Kelley MR, LeDoux SP, Wilson GL 2002 Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria. J Biol Chem 277:44932-44937 (Pubitemid 36159090)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 44932-44937
-
-
Rachek, L.I.1
Grishko, V.I.2
Musiyenko, S.I.3
Kelley, M.R.4
LeDoux, S.P.5
Wilson, G.L.6
-
3
-
-
33644661625
-
Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis
-
DOI 10.1016/j.freeradbiomed.2005.09.028, PII S0891584905005575
-
Rachek LI, Grishko VI, Ledoux SP, Wilson GL 2006 Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis. Free Radic Biol Med 40:754-762 (Pubitemid 43327310)
-
(2006)
Free Radical Biology and Medicine
, vol.40
, Issue.5
, pp. 754-762
-
-
Rachek, L.I.1
Grishko, V.I.2
LeDoux, S.P.3
Wilson, G.L.4
-
4
-
-
33745314333
-
Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria
-
DOI 10.2337/diabetes.55.04.06.db05-0865
-
Rachek LI, Thornley NP, Grishko VI, LeDoux SP, Wilson GL 2006 Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria. Diabetes 55:1022-1028 (Pubitemid 44100177)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 1022-1028
-
-
Rachek, L.I.1
Thornley, N.P.2
Grishko, V.I.3
LeDoux, S.P.4
Wilson, G.L.5
-
5
-
-
39349111970
-
Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis
-
DOI 10.1152/ajpcell.00362.2007
-
Ricci C, Pastukh V, Leonard J, Turrens J, Wilson G, Schaffer D, Schaffer SW 2008 Mitochondrial DNA damage triggers mitochondrial- superoxide generation and apoptosis. Am J Physiol Cell Physiol 294:C413-C422 (Pubitemid 351264418)
-
(2008)
American Journal of Physiology - Cell Physiology
, vol.294
, Issue.2
-
-
Ricci, C.1
Pastukh, V.2
Leonard, J.3
Turrens, J.4
Wilson, G.5
Schaffer, D.6
Schaffer, S.W.7
-
6
-
-
76549113814
-
Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes
-
Kim J, Xu M, Xo R, Mates A, Wilson GL, Pearsall 4th AW, Grishko V 2010 Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes. Osteoarthritis Cartilage 18:424-432
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 424-432
-
-
Kim, J.1
Xu, M.2
Xo, R.3
Mates, A.4
Wilson, G.L.5
Pearsall IV, A.W.6
Grishko, V.7
-
7
-
-
15444375759
-
Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes
-
DOI 10.1074/jbc.M409399200
-
Park SY, Choi GH, Choi HI, Ryu J, Jung CY, Lee W 2005 Depletion of mitochondrial DNA causes impaired glucose utilization and insulin resistance in L6 GLUT4myc myocytes. J Biol Chem 280:9855-9864 (Pubitemid 40395832)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 9855-9864
-
-
Park, S.Y.1
Choi, G.H.2
Choi, H.I.3
Ryu, J.4
Jung, C.Y.5
Lee, W.6
-
8
-
-
32444434993
-
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase
-
DOI 10.1073/pnas.0507444103
-
Vartanian V, Lowell B, Minko IG, Wood TG, Ceci JD, George S, Ballinger SW, Corless CL, McCullough AK, Lloyd RS 2006 The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci USA 103:1864-1869 (Pubitemid 43228784)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.6
, pp. 1864-1869
-
-
Vartanian, V.1
Lowell, B.2
Minko, I.G.3
Wood, T.G.4
Ceci, J.D.5
George, S.6
Ballinger, S.W.7
Corless, C.L.8
McCullough, A.K.9
Lloyd, R.S.10
-
9
-
-
0033537931
-
Identification of enhanced serine kinase activity in insulin resistance
-
Qiao LY, Goldberg JL, Russell JC, Sun XJ 1999 Identification of enhanced serine kinase activity in insulin resistance. J Biol Chem 274:10625-10632
-
(1999)
J Biol Chem
, vol.274
, pp. 10625-10632
-
-
Qiao, L.Y.1
Goldberg, J.L.2
Russell, J.C.3
Sun, X.J.4
-
10
-
-
28844478775
-
Repair of formamidopyrimidines in DNA involves different glycosylases: Role of the OGG1, NTH1, and NEIL1 enzymes
-
DOI 10.1074/jbc.M508772200
-
Hu J, de Souza-Pinto NC, Haraguchi K, Hogue BA, Jaruga P, Greenberg MM, Dizdaroglu M, Bohr VA 2005 Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem 280:40544-40551 (Pubitemid 41780543)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 40544-40551
-
-
Hu, J.1
De Souza-Pinto, N.C.2
Haraguchi, K.3
Hogue, B.A.4
Jaruga, P.5
Greenberg, M.M.6
Dizdaroglu, M.7
Bohr, V.A.8
-
11
-
-
0031004167
-
Increased prevalence of mitochondrial DNA deletions in skeletal muscle of older individuals with impaired glucose tolerance: Possible marker of glycemic stress
-
Liang P, Hughes V, Fukagawa NK 1997 Increased prevalence of mitochondrial DNA deletions in skeletal muscle of older individuals with impaired glucose tolerance: possible marker of glycemic stress. Diabetes 46:920-923 (Pubitemid 27188275)
-
(1997)
Diabetes
, vol.46
, Issue.5
, pp. 920-923
-
-
Liang, P.1
Hughes, V.2
Fukagawa, N.K.3
-
12
-
-
62749102812
-
m. 3243A>G mutation in mitochondrial DNA leads to decreased insulin sensitivity in skeletal muscle and to progressive β-cell dysfunction
-
Lindroos MM, Majamaa K, Tura A, Mari A, Kalliokoski KK, Taittonen MT, Iozzo P, Nuutila P 2009 m. 3243A>G mutation in mitochondrial DNA leads to decreased insulin sensitivity in skeletal muscle and to progressive β-cell dysfunction. Diabetes 58:543-549
-
(2009)
Diabetes
, vol.58
, pp. 543-549
-
-
Lindroos, M.M.1
Majamaa, K.2
Tura, A.3
Mari, A.4
Kalliokoski, K.K.5
Taittonen, M.T.6
Iozzo, P.7
Nuutila, P.8
-
13
-
-
33845895308
-
Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in L6 rat skeletal muscle cells
-
DOI 10.1210/en.2006-0998
-
Rachek LI, Musiyenko SI, LeDoux SP, Wilson GL 2007 Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in l6 rat skeletal muscle cells. Endocrinology 148:293-299 (Pubitemid 46021461)
-
(2007)
Endocrinology
, vol.148
, Issue.1
, pp. 293-299
-
-
Rachek, L.I.1
Musiyenko, S.I.2
LeDoux, S.P.3
Wilson, G.L.4
-
14
-
-
70349779185
-
Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes
-
Rachek LI, Yuzefovych LV, Ledoux SP, Julie NL, Wilson GL 2009 Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes. Toxicol Appl Pharmacol 240:348-354
-
(2009)
Toxicol Appl Pharmacol
, vol.240
, pp. 348-354
-
-
Rachek, L.I.1
Yuzefovych, L.V.2
Ledoux, S.P.3
Julie, N.L.4
Wilson, G.L.5
-
15
-
-
0026609929
-
Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells
-
Mitsumoto Y, Klip A 1992 Development regulation of the subcellular distribution and glycosylation of GLUT1 and GLUT4 glucose transporters during myogenesis of L6 muscle cells. J Biol Chem 267: 4957-4962
-
(1992)
J Biol Chem
, vol.267
, pp. 4957-4962
-
-
Mitsumoto, Y.1
Klip, A.2
-
16
-
-
0036300508
-
Sustained exposure of L6 myotubes to high glucose and insulin decreases insulin-stimulated GLUT4 translocation but upregulates GLUT4 activity
-
Huang C, Somwar R, Patel N, Niu W, Török D, Klip A 2002 Sustained exposure of L6 myotubes to high glucose and insulin decreases insulin-stimulated GLUT4 translocation but upregulates GLUT4 activity. Diabetes 51:2090-2098 (Pubitemid 34729012)
-
(2002)
Diabetes
, vol.51
, Issue.7
, pp. 2090-2098
-
-
Huang, C.1
Somwar, R.2
Patel, N.3
Niu, W.4
Torok, D.5
Klip, A.6
-
17
-
-
67349151662
-
Inhibition of NFκB by activated c-Jun NH2 terminal kinase 1 acts as a switch for C2C12 cell death under excessive stretch
-
Tan J, Kuang W, Jin Z, Jin F, Xu L, Yu Q, Kong L, Zeng G, Yuan X, Duan Y 2009 Inhibition of NFκB by activated c-Jun NH2 terminal kinase 1 acts as a switch for C2C12 cell death under excessive stretch. Apoptosis 14:764-770
-
(2009)
Apoptosis
, vol.14
, pp. 764-770
-
-
Tan, J.1
Kuang, W.2
Jin, Z.3
Jin, F.4
Xu, L.5
Yu, Q.6
Kong, L.7
Zeng, G.8
Yuan, X.9
Duan, Y.10
-
18
-
-
34249915334
-
Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
-
DOI 10.1172/JCI30566
-
Schenk S, Horowitz JF 2007 Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. J Clin Invest 117:1690-1698 (Pubitemid 46871353)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1690-1698
-
-
Schenk, S.1
Horowitz, J.F.2
-
19
-
-
67649304876
-
Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria
-
Nakamura S, Takamura T, Matsuzawa-Nagata N, Takayama H, Misu H, Noda H, Nabemoto S, Kurita S, Ota T, Ando H, Miyamoto K, Kaneko S 2009 Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria. J Biol Chem 284:14809-14818
-
(2009)
J Biol Chem
, vol.284
, pp. 14809-14818
-
-
Nakamura, S.1
Takamura, T.2
Matsuzawa-Nagata, N.3
Takayama, H.4
Misu, H.5
Noda, H.6
Nabemoto, S.7
Kurita, S.8
Ota, T.9
Ando, H.10
Miyamoto, K.11
Kaneko, S.12
-
20
-
-
51449103367
-
Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells
-
Pimenta AS, Gaidhu MP, Habib S, So M, Fediuc S, Mirpourian M, Musheev M, Curi R, Ceddia RB 2008 Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells. J Cell Physiol 217:478-485
-
(2008)
J Cell Physiol
, vol.217
, pp. 478-485
-
-
Pimenta, A.S.1
Gaidhu, M.P.2
Habib, S.3
So, M.4
Fediuc, S.5
Mirpourian, M.6
Musheev, M.7
Curi, R.8
Ceddia, R.B.9
-
21
-
-
79959262123
-
Palmitic acid acutely stimulates glucose uptake via activation of Akt and ERK1/2 in skeletal muscle cells
-
Pu J, Peng G, Li L, Na H, Liu Y, Liu P 2011 Palmitic acid acutely stimulates glucose uptake via activation of Akt and ERK1/2 in skeletal muscle cells. J Lipid Res 52:1319-1327
-
(2011)
J Lipid Res
, vol.52
, pp. 1319-1327
-
-
Pu, J.1
Peng, G.2
Li, L.3
Na, H.4
Liu, Y.5
Liu, P.6
-
22
-
-
70350463891
-
Repair of nitric oxide-damaged DNA in β-cells requires JNK-dependent GADD45α expression
-
Hughes KJ, Meares GP, Chambers KT, Corbett JA 2009 Repair of nitric oxide-damaged DNA in β-cells requires JNK-dependent GADD45α expression. J Biol Chem 284:27402-27408
-
(2009)
J Biol Chem
, vol.284
, pp. 27402-27408
-
-
Hughes, K.J.1
Meares, G.P.2
Chambers, K.T.3
Corbett, J.A.4
-
23
-
-
38849199866
-
Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice
-
DOI 10.1172/JCI32601
-
Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, Vidal H, Rieusset J 2008 Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulinresistant mice. J Clin Invest 118:789-800 (Pubitemid 351206566)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 789-800
-
-
Bonnard, C.1
Durand, A.2
Peyrol, S.3
Chanseaume, E.4
Chauvin, M.-A.5
Morio, B.6
Vidal, H.7
Rieusset, J.8
-
24
-
-
67650815430
-
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
-
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price 3rd JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD 2009 Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119: 573-581
-
(2009)
J Clin Invest
, vol.119
, pp. 573-581
-
-
Anderson, E.J.1
Lustig, M.E.2
Boyle, K.E.3
Woodlief, T.L.4
Kane, D.A.5
Lin, C.T.6
Price III, J.W.7
Kang, L.8
Rabinovitch, P.S.9
Szeto, H.H.10
Houmard, J.A.11
Cortright, R.N.12
Wasserman, D.H.13
Neufer, P.D.14
-
25
-
-
78649497300
-
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance
-
Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI 2010 Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance. Cell Metab 12:668-674
-
(2010)
Cell Metab
, vol.12
, pp. 668-674
-
-
Lee, H.Y.1
Choi, C.S.2
Birkenfeld, A.L.3
Alves, T.C.4
Jornayvaz, F.R.5
Jurczak, M.J.6
Zhang, D.7
Woo, D.K.8
Shadel, G.S.9
Ladiges, W.10
Rabinovitch, P.S.11
Santos, J.H.12
Petersen, K.F.13
Samuel, V.T.14
Shulman, G.I.15
-
26
-
-
70449552861
-
Insulin resistance is a cellular antioxidant defense mechanism
-
Hoehn KL, Salmon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ, Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James DE 2009 Insulin resistance is a cellular antioxidant defense mechanism. Proc Natl Acad Sci USA 106:17787-17792
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17787-17792
-
-
Hoehn, K.L.1
Salmon, A.B.2
Hohnen-Behrens, C.3
Turner, N.4
Hoy, A.J.5
Maghzal, G.J.6
Stocker, R.7
Van Remmen, H.8
Kraegen, E.W.9
Cooney, G.J.10
Richardson, A.R.11
James, D.E.12
-
27
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
Houstis N, Rosen ED, Lander ES 2006 Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440: 944-948
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
28
-
-
48749100078
-
Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells
-
Lambertucci RH, Hirabara SM, Silveira Ldos R, Levada-Pires AC, Curi R, Pithon-Curi TC 2008 Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells. J Cell Physiol 216: 796-804
-
(2008)
J Cell Physiol
, vol.216
, pp. 796-804
-
-
Lambertucci, R.H.1
Hirabara, S.M.2
Silveira Ldos, R.3
Levada-Pires, A.C.4
Curi, R.5
Pithon-Curi, T.C.6
-
29
-
-
0030046495
-
Mitochondria and diabetes: Genetic, biochemical, and clinical implications of the cellular energy circuit
-
Gerbitz KD, Gempel K, Brdiczka D 1996 Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit. Diabetes 45:113-126 (Pubitemid 26045791)
-
(1996)
Diabetes
, vol.45
, Issue.2
, pp. 113-126
-
-
Gerbitz, K.-D.1
Gempel, K.2
Brdiczka, D.3
-
30
-
-
0033230607
-
Role of redox potential and reactive oxygen species in stress signaling
-
Adler V, Yin Z, Tew KD, Ronai Z 1999 Role of redox potential and reactive oxygen species in stress signaling. Oncogene 18:6104-6111
-
(1999)
Oncogene
, vol.18
, pp. 6104-6111
-
-
Adler, V.1
Yin, Z.2
Tew, K.D.3
Ronai, Z.4
-
31
-
-
43849104298
-
Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: Evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance
-
DOI 10.1677/JOE-08-0061
-
Vinayagamoorthi R, Bobby Z, Sridhar MG 2008 Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance. J Endocrinol 197:287-296 (Pubitemid 351696241)
-
(2008)
Journal of Endocrinology
, vol.197
, Issue.2
, pp. 287-296
-
-
Vinayagamoorthi, R.1
Bobby, Z.2
Sridhar, M.G.3
-
32
-
-
66149153033
-
Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
-
Gupte AA, Bomhoff GL, Morris JK, Gorres BK, Geiger PC 2009 Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats. J Appl Physiol 106:1425-1434
-
(2009)
J Appl Physiol
, vol.106
, pp. 1425-1434
-
-
Gupte, A.A.1
Bomhoff, G.L.2
Morris, J.K.3
Gorres, B.K.4
Geiger, P.C.5
-
33
-
-
79551600855
-
Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice
-
Zhang X, Xu A, Chung SK, Cresser JH, Sweeney G, Wong RL, Lin A, Lam KS 2011 Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice. Diabetes 60:486-495
-
(2011)
Diabetes
, vol.60
, pp. 486-495
-
-
Zhang, X.1
Xu, A.2
Chung, S.K.3
Cresser, J.H.4
Sweeney, G.5
Wong, R.L.6
Lin, A.7
Lam, K.S.8
|