ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

Genes and Development

Volumn 27, Issue 22, 2013, Pages 2459-2472

  Yamada, Masayuki ^a,b   Watanabe, Kenji ^b   Mistrik, Martin ^a   Vesela, Eva ^a   Protivankova, Iva ^a   Mailand, Niels ^b,c   Lee, Myung Hee ^b   Masai, Hisao ^d   Lukas, Jiri ^b,c   Bartek, Jiri ^a,b  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^c University of Copenhagen   (Denmark)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

APC CCdh1; Cdc7; Chk1; DNA lesion bypass; RAD18; Replication stress

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CHECKPOINT KINASE 1; DNA POLYMERASE; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CHROMATIN; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS; ENZYME DEGRADATION; GENETIC REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; UBIQUITINATION;

APC/CCDH1; CDC7; CHK1; DNA LESION BYPASS; RAD18; REPLICATION STRESS;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; CADHERINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DNA REPLICATION; ENZYME STABILITY; GENES, APC; HEK293 CELLS; HELA CELLS; HUMANS; PROTEIN BINDING; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84887574546     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.224568.113     Document Type: Article

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