-
1
-
-
0038205695
-
Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection
-
Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, Baril JG, Dion H, Lefebvre E, Thomas R, Cote P, Lapointe N, Routy JP, Sekaly RP, Conway B, Bernard NF. Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection. J Immunol 2003, 171:477-488.
-
(2003)
J Immunol
, vol.171
, pp. 477-488
-
-
Alter, G.1
Hatzakis, G.2
Tsoukas, C.M.3
Pelley, K.4
Rouleau, D.5
LeBlanc, R.6
Baril, J.G.7
Dion, H.8
Lefebvre, E.9
Thomas, R.10
Cote, P.11
Lapointe, N.12
Routy, J.P.13
Sekaly, R.P.14
Conway, B.15
Bernard, N.F.16
-
2
-
-
33947606768
-
Slow disease progression and robust therapy-mediated CD4(+) T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection
-
Dion ML, Bordi R, Zeidan J, Asaad R, Boulassel MR, Routy JP, Lederman MM, Sekaly RP, Cheynier R. Slow disease progression and robust therapy-mediated CD4(+) T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection. Blood 2007, 109:2912-2920.
-
(2007)
Blood
, vol.109
, pp. 2912-2920
-
-
Dion, M.L.1
Bordi, R.2
Zeidan, J.3
Asaad, R.4
Boulassel, M.R.5
Routy, J.P.6
Lederman, M.M.7
Sekaly, R.P.8
Cheynier, R.9
-
3
-
-
17444372347
-
Changes in thymic function with age and during the treatment of HIV infection
-
10.1038/25374, 9872319
-
Douek DC, McFarland RD, Keiser PH, Gage EA, Massey JM, Haynes BF, Polis MA, Haase AT, Feinberg MB, Sullivan JL, Jamieson BD, Zack JA, Picker LJ, Koup RA. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998, 396:690-695. 10.1038/25374, 9872319.
-
(1998)
Nature
, vol.396
, pp. 690-695
-
-
Douek, D.C.1
McFarland, R.D.2
Keiser, P.H.3
Gage, E.A.4
Massey, J.M.5
Haynes, B.F.6
Polis, M.A.7
Haase, A.T.8
Feinberg, M.B.9
Sullivan, J.L.10
Jamieson, B.D.11
Zack, J.A.12
Picker, L.J.13
Koup, R.A.14
-
4
-
-
0033557266
-
Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection
-
10.1172/JCI5201, 408098, 10021452
-
Haynes BF, Hale LP, Weinhold KJ, Patel DD, Liao HX, Bressler PB, Jones DM, Demarest JF, Gebhard-Mitchell K, Haase AT, Bartlett JA. Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection. J Clin Invest 1999, 103:453-460. 10.1172/JCI5201, 408098, 10021452.
-
(1999)
J Clin Invest
, vol.103
, pp. 453-460
-
-
Haynes, B.F.1
Hale, L.P.2
Weinhold, K.J.3
Patel, D.D.4
Liao, H.X.5
Bressler, P.B.6
Jones, D.M.7
Demarest, J.F.8
Gebhard-Mitchell, K.9
Haase, A.T.10
Bartlett, J.A.11
-
5
-
-
0025841849
-
Thymus in simian immunodeficiency virus-infected rhesus-monkeys
-
Baskin GB, Murpheycorb M, Martin LN, Davisonfairburn B, Hu FS, Kuebler D. Thymus in simian immunodeficiency virus-infected rhesus-monkeys. Lab Invest 1991, 65:400-407.
-
(1991)
Lab Invest
, vol.65
, pp. 400-407
-
-
Baskin, G.B.1
Murpheycorb, M.2
Martin, L.N.3
Davisonfairburn, B.4
Hu, F.S.5
Kuebler, D.6
-
6
-
-
0032101595
-
Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus
-
10.1084/jem.187.11.1767, 2212305, 9607918
-
Wykrzykowska JJ, Rosenzweig M, Veazey RS, Simon MA, Halvorsen K, Desrosiers RC, Johnson RP, Lackner AA. Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus. J Exp Med 1998, 187:1767-1778. 10.1084/jem.187.11.1767, 2212305, 9607918.
-
(1998)
J Exp Med
, vol.187
, pp. 1767-1778
-
-
Wykrzykowska, J.J.1
Rosenzweig, M.2
Veazey, R.S.3
Simon, M.A.4
Halvorsen, K.5
Desrosiers, R.C.6
Johnson, R.P.7
Lackner, A.A.8
-
7
-
-
0036776605
-
Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus
-
10.1128/JVI.76.19.9981-9990.2002, 136511, 12208974
-
Sodora DL, Milush JM, Ware F, Wozniakowski A, Montgomery L, McClure HM, Lackner AA, Marthas M, Hirsch V, Johnson RP, Douek DC, Koup RA. Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus. J Virol 2002, 76:9981-9990. 10.1128/JVI.76.19.9981-9990.2002, 136511, 12208974.
-
(2002)
J Virol
, vol.76
, pp. 9981-9990
-
-
Sodora, D.L.1
Milush, J.M.2
Ware, F.3
Wozniakowski, A.4
Montgomery, L.5
McClure, H.M.6
Lackner, A.A.7
Marthas, M.8
Hirsch, V.9
Johnson, R.P.10
Douek, D.C.11
Koup, R.A.12
-
8
-
-
0025743306
-
Importance of the Nef gene for maintenance of high virus loads and for development of aids
-
10.1016/0092-8674(91)90097-I, 2032289
-
Kestler HW, Ringler DJ, Mori K, Panicali DL, Sehgal PK, Daniel MD, Desrosiers RC. Importance of the Nef gene for maintenance of high virus loads and for development of aids. Cell 1991, 65:651-662. 10.1016/0092-8674(91)90097-I, 2032289.
-
(1991)
Cell
, vol.65
, pp. 651-662
-
-
Kestler, H.W.1
Ringler, D.J.2
Mori, K.3
Panicali, D.L.4
Sehgal, P.K.5
Daniel, M.D.6
Desrosiers, R.C.7
-
9
-
-
0028804160
-
Genomic structure of an attenuated quasi-species of Hiv-1 from a blood-transfusion donor and recipients
-
10.1126/science.270.5238.988, 7481804
-
Deacon NJ, Tsykin A, Solomon A, Smith K, Ludfordmenting M, Hooker DJ, McPhee DA, Greenway AL, Ellett A, Chatfield C, Lawson VA, Crowe S, Maerz A, Sonza S, Learmont J, Sullivan JS, Cunningham A, Dwyer D, Dowton D, Mills J. Genomic structure of an attenuated quasi-species of Hiv-1 from a blood-transfusion donor and recipients. Science 1995, 270:988-991. 10.1126/science.270.5238.988, 7481804.
-
(1995)
Science
, vol.270
, pp. 988-991
-
-
Deacon, N.J.1
Tsykin, A.2
Solomon, A.3
Smith, K.4
Ludfordmenting, M.5
Hooker, D.J.6
McPhee, D.A.7
Greenway, A.L.8
Ellett, A.9
Chatfield, C.10
Lawson, V.A.11
Crowe, S.12
Maerz, A.13
Sonza, S.14
Learmont, J.15
Sullivan, J.S.16
Cunningham, A.17
Dwyer, D.18
Dowton, D.19
Mills, J.20
more..
-
10
-
-
0028835788
-
Brief report - absence of intact Nef sequences in a long-term survivor with nonprogressive Hiv-1 infection
-
10.1056/NEJM199501263320405, 7808489
-
Kirchhoff F, Greenough TC, Brettler DB, Sullivan JL, Desrosiers RC. Brief report - absence of intact Nef sequences in a long-term survivor with nonprogressive Hiv-1 infection. N Engl J Med 1995, 332:228-232. 10.1056/NEJM199501263320405, 7808489.
-
(1995)
N Engl J Med
, vol.332
, pp. 228-232
-
-
Kirchhoff, F.1
Greenough, T.C.2
Brettler, D.B.3
Sullivan, J.L.4
Desrosiers, R.C.5
-
11
-
-
0032538278
-
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
-
10.1016/S0092-8674(00)81748-1, 9790524
-
Hanna Z, Kay DG, Rebai N, Guimond A, Jothy S, Jolicoeur P. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 1998, 95:163-175. 10.1016/S0092-8674(00)81748-1, 9790524.
-
(1998)
Cell
, vol.95
, pp. 163-175
-
-
Hanna, Z.1
Kay, D.G.2
Rebai, N.3
Guimond, A.4
Jothy, S.5
Jolicoeur, P.6
-
12
-
-
0027955426
-
Severe immunodeficiency associated with a human-immunodeficiency-virus-1 Nef/3' long terminal repeat transgene
-
10.1084/jem.179.3.797, 2191393, 8113676
-
Lindemann D, Wilhelm R, Renard P, Althage A, Zinkernagel R, Mous J. Severe immunodeficiency associated with a human-immunodeficiency-virus-1 Nef/3' long terminal repeat transgene. J Exp Med 1994, 179:797-807. 10.1084/jem.179.3.797, 2191393, 8113676.
-
(1994)
J Exp Med
, vol.179
, pp. 797-807
-
-
Lindemann, D.1
Wilhelm, R.2
Renard, P.3
Althage, A.4
Zinkernagel, R.5
Mous, J.6
-
13
-
-
0027533215
-
Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
-
413256, 8095017
-
Skowronski J, Parks D, Mariani R. Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J 1993, 12:703-713. 413256, 8095017.
-
(1993)
EMBO J
, vol.12
, pp. 703-713
-
-
Skowronski, J.1
Parks, D.2
Mariani, R.3
-
14
-
-
47749133802
-
HIV Nef: role in pathogenesis and viral fitness
-
10.2174/157016208784325001, 18473783
-
Arien KK, Verhasselt B. HIV Nef: role in pathogenesis and viral fitness. Curr HIV Res 2008, 6:200-208. 10.2174/157016208784325001, 18473783.
-
(2008)
Curr HIV Res
, vol.6
, pp. 200-208
-
-
Arien, K.K.1
Verhasselt, B.2
-
15
-
-
77958182786
-
Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses
-
10.1016/j.chom.2010.06.004, 20638642
-
Kirchhoff F. Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses. Cell Host Microbe 2010, 8:55-67. 10.1016/j.chom.2010.06.004, 20638642.
-
(2010)
Cell Host Microbe
, vol.8
, pp. 55-67
-
-
Kirchhoff, F.1
-
16
-
-
74849088296
-
Implications of Nef: host cell interactions in viral persistence and progression to AIDS
-
Berlin: Springer-Verlag Berlin
-
Arhel NJ, Kirchhoff F. Implications of Nef: host cell interactions in viral persistence and progression to AIDS. Curr Top Microbiol Immunol Volume 339 2009, 147-175. Berlin: Springer-Verlag Berlin.
-
(2009)
Curr Top Microbiol Immunol Volume 339
, pp. 147-175
-
-
Arhel, N.J.1
Kirchhoff, F.2
-
17
-
-
84856453839
-
The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection
-
10.2174/157016211798842099, 3355465, 22103831
-
Vermeire J, Vanbillemont G, Witkowski W, Verhasselt B. The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection. Curr HIV Res 2011, 9:474-489. 10.2174/157016211798842099, 3355465, 22103831.
-
(2011)
Curr HIV Res
, vol.9
, pp. 474-489
-
-
Vermeire, J.1
Vanbillemont, G.2
Witkowski, W.3
Verhasselt, B.4
-
18
-
-
84856499935
-
One protein to rule them All: modulation of cell surface receptors and molecules by HIV Nef
-
10.2174/157016211798842116, 3290772, 22103833
-
Landi A, Iannucci V, Van Nuffel A, Meuwissen P, Verhasselt B. One protein to rule them All: modulation of cell surface receptors and molecules by HIV Nef. Curr HIV Res 2011, 9:496-504. 10.2174/157016211798842116, 3290772, 22103833.
-
(2011)
Curr HIV Res
, vol.9
, pp. 496-504
-
-
Landi, A.1
Iannucci, V.2
Van Nuffel, A.3
Meuwissen, P.4
Verhasselt, B.5
-
19
-
-
72849136276
-
Downregulation of the T-cell receptor by human immunodeficiency virus type 2 Nef does Not protect against disease progression
-
10.1128/JVI.01252-09, 2786859, 19812166
-
Feldmann J, Leligdowicz A, Jaye A, Dong T, Whittle H, Rowland-Jones SL. Downregulation of the T-cell receptor by human immunodeficiency virus type 2 Nef does Not protect against disease progression. J Virol 2009, 83:12968-12972. 10.1128/JVI.01252-09, 2786859, 19812166.
-
(2009)
J Virol
, vol.83
, pp. 12968-12972
-
-
Feldmann, J.1
Leligdowicz, A.2
Jaye, A.3
Dong, T.4
Whittle, H.5
Rowland-Jones, S.L.6
-
20
-
-
0035138509
-
Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates
-
10.1128/JVI.75.4.1672-1680.2001, 114076, 11160665
-
Foster JL, Molina RP, Luo T, Arora VK, Huang Y, Ho DD, Garcia JV. Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates. J Virol 2001, 75:1672-1680. 10.1128/JVI.75.4.1672-1680.2001, 114076, 11160665.
-
(2001)
J Virol
, vol.75
, pp. 1672-1680
-
-
Foster, J.L.1
Molina, R.P.2
Luo, T.3
Arora, V.K.4
Huang, Y.5
Ho, D.D.6
Garcia, J.V.7
-
21
-
-
0031774858
-
Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2
-
110494, 9811718
-
Howe AYM, Jung JU, Desrosiers RC. Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2. J Virol 1998, 72:9827-9834. 110494, 9811718.
-
(1998)
J Virol
, vol.72
, pp. 9827-9834
-
-
Howe, A.Y.M.1
Jung, J.U.2
Desrosiers, R.C.3
-
22
-
-
23244465720
-
Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication
-
10.1128/JVI.79.16.10547-10560.2005, 1182674, 16051847
-
Munch J, Schindler M, Wildum S, Rucker E, Bailer N, Knoop V, Novembre FJ, Kirchhoff F. Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication. J Virol 2005, 79:10547-10560. 10.1128/JVI.79.16.10547-10560.2005, 1182674, 16051847.
-
(2005)
J Virol
, vol.79
, pp. 10547-10560
-
-
Munch, J.1
Schindler, M.2
Wildum, S.3
Rucker, E.4
Bailer, N.5
Knoop, V.6
Novembre, F.J.7
Kirchhoff, F.8
-
23
-
-
34248572102
-
Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors
-
10.1097/QAD.0b013e32816aa37c, 17502720
-
Schindler M, Wildum S, Casartelli N, Doria M, Kirchhoff F. Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors. AIDS 2007, 21:1103-1107. 10.1097/QAD.0b013e32816aa37c, 17502720.
-
(2007)
AIDS
, vol.21
, pp. 1103-1107
-
-
Schindler, M.1
Wildum, S.2
Casartelli, N.3
Doria, M.4
Kirchhoff, F.5
-
24
-
-
0032855131
-
Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells
-
Verhasselt B, Naessens E, Verhofstede C, De Smedt M, Schollen S, Kerre T, Vanhecke D, Plum J. Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells. Blood 1999, 94:2809-2818.
-
(1999)
Blood
, vol.94
, pp. 2809-2818
-
-
Verhasselt, B.1
Naessens, E.2
Verhofstede, C.3
De Smedt, M.4
Schollen, S.5
Kerre, T.6
Vanhecke, D.7
Plum, J.8
-
25
-
-
0141993006
-
Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development
-
10.1182/blood-2003-03-0833, 12855553
-
Stove V, Naessens E, Stove C, Swigut T, Plum J, Verhasselt B. Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development. Blood 2003, 102:2925-2932. 10.1182/blood-2003-03-0833, 12855553.
-
(2003)
Blood
, vol.102
, pp. 2925-2932
-
-
Stove, V.1
Naessens, E.2
Stove, C.3
Swigut, T.4
Plum, J.5
Verhasselt, B.6
-
26
-
-
44849138169
-
HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor
-
Dorival C, Brizzi F, Lelievre JD, Sol-Foulon N, Six E, Henry A, Andre-Schmutz I, Cavazzana-Calvo M, Coulombel L, Estaquier J, Schwartz O, Levy Y. HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor. Virol 2008, 377:207-215.
-
(2008)
Virol
, vol.377
, pp. 207-215
-
-
Dorival, C.1
Brizzi, F.2
Lelievre, J.D.3
Sol-Foulon, N.4
Six, E.5
Henry, A.6
Andre-Schmutz, I.7
Cavazzana-Calvo, M.8
Coulombel, L.9
Estaquier, J.10
Schwartz, O.11
Levy, Y.12
-
27
-
-
84861419814
-
Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes
-
Zou W, Denton PW, Watkins RL, Krisko JF, Nochi T, Foster JL, Garcia JV. Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes. Retrovirol 2012, 9:44.
-
(2012)
Retrovirol
, vol.9
, pp. 44
-
-
Zou, W.1
Denton, P.W.2
Watkins, R.L.3
Krisko, J.F.4
Nochi, T.5
Foster, J.L.6
Garcia, J.V.7
-
28
-
-
33745070227
-
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1
-
10.1016/j.cell.2006.04.033, 16777597
-
Schindler M, Munch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Muller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F. Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell 2006, 125:1055-1067. 10.1016/j.cell.2006.04.033, 16777597.
-
(2006)
Cell
, vol.125
, pp. 1055-1067
-
-
Schindler, M.1
Munch, J.2
Kutsch, O.3
Li, H.4
Santiago, M.L.5
Bibollet-Ruche, F.6
Muller-Trutwin, M.C.7
Novembre, F.J.8
Peeters, M.9
Courgnaud, V.10
Bailes, E.11
Roques, P.12
Sodora, D.L.13
Silvestri, G.14
Sharp, P.M.15
Hahn, B.H.16
Kirchhoff, F.17
-
29
-
-
84860201476
-
Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function
-
Meuwissen PJ, Stolp B, Iannucci V, Vermeire J, Naessens E, Saksela K, Geyer M, Vanham G, Arien KK, Fackler OT, Verhasselt B. Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function. Retrovirol 2012, 9:34.
-
(2012)
Retrovirol
, vol.9
, pp. 34
-
-
Meuwissen, P.J.1
Stolp, B.2
Iannucci, V.3
Vermeire, J.4
Naessens, E.5
Saksela, K.6
Geyer, M.7
Vanham, G.8
Arien, K.K.9
Fackler, O.T.10
Verhasselt, B.11
-
30
-
-
84861627468
-
Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix
-
Kuo LS, Baugh LL, Denial SJ, Watkins RL, Liu MJ, Garcia JV, Foster JL. Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix. Retrovirol 2012, 9:47.
-
(2012)
Retrovirol
, vol.9
, pp. 47
-
-
Kuo, L.S.1
Baugh, L.L.2
Denial, S.J.3
Watkins, R.L.4
Liu, M.J.5
Garcia, J.V.6
Foster, J.L.7
-
31
-
-
77950514618
-
Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling
-
10.1128/JVI.02467-09, 2849517, 20147394
-
Stolp B, Abraham L, Rudolph JM, Fackler OT. Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling. J Virol 2010, 84:3935-3948. 10.1128/JVI.02467-09, 2849517, 20147394.
-
(2010)
J Virol
, vol.84
, pp. 3935-3948
-
-
Stolp, B.1
Abraham, L.2
Rudolph, J.M.3
Fackler, O.T.4
-
32
-
-
0029328618
-
Nucleotide-sequence of the HIV-2 EHO genome, a divergent HIV-2 isolate
-
10.1089/aid.1995.11.873, 7546916
-
Galabru J, Reycuille MA, Hovanessian AG. Nucleotide-sequence of the HIV-2 EHO genome, a divergent HIV-2 isolate. AIDS Res Hum Retrovir 1995, 11:873-874. 10.1089/aid.1995.11.873, 7546916.
-
(1995)
AIDS Res Hum Retrovir
, vol.11
, pp. 873-874
-
-
Galabru, J.1
Reycuille, M.A.2
Hovanessian, A.G.3
-
33
-
-
78650646751
-
The presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 Are Not always linked in primate lentiviruses
-
10.1128/JVI.02087-10, 3020008, 21068258
-
Schmokel J, Sauter D, Schindler M, Leendertz FH, Bailes E, Dazza MC, Saragosti S, Bibollet-Ruche F, Peeters M, Hahn BH, Kirchhoff F. The presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 Are Not always linked in primate lentiviruses. J Virol 2011, 85:742-752. 10.1128/JVI.02087-10, 3020008, 21068258.
-
(2011)
J Virol
, vol.85
, pp. 742-752
-
-
Schmokel, J.1
Sauter, D.2
Schindler, M.3
Leendertz, F.H.4
Bailes, E.5
Dazza, M.C.6
Saragosti, S.7
Bibollet-Ruche, F.8
Peeters, M.9
Hahn, B.H.10
Kirchhoff, F.11
-
34
-
-
23244459907
-
Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1
-
10.1128/JVI.79.16.10650-10659.2005, 1182621, 16051857
-
Hrecka K, Swigut T, Schindler M, Kirchhoff F, Skowronski J. Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1. J Virol 2005, 79:10650-10659. 10.1128/JVI.79.16.10650-10659.2005, 1182621, 16051857.
-
(2005)
J Virol
, vol.79
, pp. 10650-10659
-
-
Hrecka, K.1
Swigut, T.2
Schindler, M.3
Kirchhoff, F.4
Skowronski, J.5
-
35
-
-
36349022028
-
Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in Ex vivo-infected human lymphoid tissue
-
10.1128/JVI.01436-07, 2169106, 17881449
-
Schindler M, Rajan D, Specht A, Ritter C, Pulkkinen K, Saksela K, Kirchhoff F. Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in Ex vivo-infected human lymphoid tissue. J Virol 2007, 81:13005-13014. 10.1128/JVI.01436-07, 2169106, 17881449.
-
(2007)
J Virol
, vol.81
, pp. 13005-13014
-
-
Schindler, M.1
Rajan, D.2
Specht, A.3
Ritter, C.4
Pulkkinen, K.5
Saksela, K.6
Kirchhoff, F.7
-
36
-
-
31144476786
-
Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef
-
10.1128/JVI.80.3.1311-1320.2006, 1346962, 16415008
-
ONeill E, Kuo LS, Krisko JF, Tomchick DR, Garcia JV, Foster JL. Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef. J Virol 2006, 80:1311-1320. 10.1128/JVI.80.3.1311-1320.2006, 1346962, 16415008.
-
(2006)
J Virol
, vol.80
, pp. 1311-1320
-
-
ONeill, E.1
Kuo, L.S.2
Krisko, J.F.3
Tomchick, D.R.4
Garcia, J.V.5
Foster, J.L.6
-
37
-
-
40149097137
-
Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity
-
10.1128/JVI.02185-07, 2259019, 18094167
-
Rauch S, Pulkkinen K, Saksela K, Fackler OT. Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity. J Virol 2008, 82:2918-2929. 10.1128/JVI.02185-07, 2259019, 18094167.
-
(2008)
J Virol
, vol.82
, pp. 2918-2929
-
-
Rauch, S.1
Pulkkinen, K.2
Saksela, K.3
Fackler, O.T.4
-
38
-
-
0033995168
-
Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques
-
10.1128/JVI.74.9.4155-4164.2000, 111930, 10756028
-
Carl S, Iafrate AJ, Lang SM, Stolte N, Stahl-Hennig C, Matz-Rensing K, Fuchs D, Skowronski J, Kirchhoff F. Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques. J Virol 2000, 74:4155-4164. 10.1128/JVI.74.9.4155-4164.2000, 111930, 10756028.
-
(2000)
J Virol
, vol.74
, pp. 4155-4164
-
-
Carl, S.1
Iafrate, A.J.2
Lang, S.M.3
Stolte, N.4
Stahl-Hennig, C.5
Matz-Rensing, K.6
Fuchs, D.7
Skowronski, J.8
Kirchhoff, F.9
-
39
-
-
4544337312
-
Comprehensive analysis of Nef functions selected in simian immunodeficiency virus-infected macaques
-
10.1128/JVI.78.19.10588-10597.2004, 516420, 15367626
-
Schindler M, Munch J, Brenner M, Stahl-Hennig C, Skowronski J, Kirchhoff F. Comprehensive analysis of Nef functions selected in simian immunodeficiency virus-infected macaques. J Virol 2004, 78:10588-10597. 10.1128/JVI.78.19.10588-10597.2004, 516420, 15367626.
-
(2004)
J Virol
, vol.78
, pp. 10588-10597
-
-
Schindler, M.1
Munch, J.2
Brenner, M.3
Stahl-Hennig, C.4
Skowronski, J.5
Kirchhoff, F.6
-
40
-
-
70349705617
-
The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses
-
2752074, 19759518
-
Arhel N, Lehmann M, Clauss K, Nienhaus GU, Piguet V, Kirchhoff F. The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses. J Clin Invest 2009, 119:2965-2975. 2752074, 19759518.
-
(2009)
J Clin Invest
, vol.119
, pp. 2965-2975
-
-
Arhel, N.1
Lehmann, M.2
Clauss, K.3
Nienhaus, G.U.4
Piguet, V.5
Kirchhoff, F.6
-
41
-
-
33644778761
-
A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2
-
10.1128/JVI.80.6.3050-3061.2006, 1395437, 16501114
-
Agopian K, Wei BL, Garcia JV, Gabuzda D. A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. J Virol 2006, 80:3050-3061. 10.1128/JVI.80.6.3050-3061.2006, 1395437, 16501114.
-
(2006)
J Virol
, vol.80
, pp. 3050-3061
-
-
Agopian, K.1
Wei, B.L.2
Garcia, J.V.3
Gabuzda, D.4
-
42
-
-
43249085765
-
HIV-1 Nef employs Two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling
-
10.1371/journal.pone.0001212, 2075162, 18030346
-
Haller C, Rauch S, Fackler OT. HIV-1 Nef employs Two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling. PLOS ONE 2007, 2:e1212. 10.1371/journal.pone.0001212, 2075162, 18030346.
-
(2007)
PLOS ONE
, vol.2
-
-
Haller, C.1
Rauch, S.2
Fackler, O.T.3
-
43
-
-
0035128420
-
Human immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIX
-
10.1128/JVI.75.5.2154-2160.2001, 114799, 11160719
-
Renkema GH, Manninen A, Saksela K. Human immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIX. J Virol 2001, 75:2154-2160. 10.1128/JVI.75.5.2154-2160.2001, 114799, 11160719.
-
(2001)
J Virol
, vol.75
, pp. 2154-2160
-
-
Renkema, G.H.1
Manninen, A.2
Saksela, K.3
-
44
-
-
8644224930
-
Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts
-
10.1128/JVI.78.23.12773-12780.2004, 524974, 15542629
-
Pulkkinen K, Renkema GH, Kirchhoff F, Saksela K. Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts. J Virol 2004, 78:12773-12780. 10.1128/JVI.78.23.12773-12780.2004, 524974, 15542629.
-
(2004)
J Virol
, vol.78
, pp. 12773-12780
-
-
Pulkkinen, K.1
Renkema, G.H.2
Kirchhoff, F.3
Saksela, K.4
-
45
-
-
0031777959
-
Role of the SH3-ligand domain of simian immunodeficiency virus nef in interaction with nef-associated kinase and simian AIDS in rhesus macaques
-
110384, 9621042
-
Khan IH, Sawai ET, Antonio E, Weber CJ, Mandell CP, Montbriand P, Luciw PA. Role of the SH3-ligand domain of simian immunodeficiency virus nef in interaction with nef-associated kinase and simian AIDS in rhesus macaques. J Virol 1998, 72:5820-5830. 110384, 9621042.
-
(1998)
J Virol
, vol.72
, pp. 5820-5830
-
-
Khan, I.H.1
Sawai, E.T.2
Antonio, E.3
Weber, C.J.4
Mandell, C.P.5
Montbriand, P.6
Luciw, P.A.7
-
46
-
-
33748673548
-
Intra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 Nef
-
10.1128/JVI.00910-06, 1563850, 16912329
-
ONeill E, Baugh LL, Novitsky VA, Essex ME, Garcia JV. Intra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 Nef. J Virol 2006, 80:8824-8829. 10.1128/JVI.00910-06, 1563850, 16912329.
-
(2006)
J Virol
, vol.80
, pp. 8824-8829
-
-
ONeill, E.1
Baugh, L.L.2
Novitsky, V.A.3
Essex, M.E.4
Garcia, J.V.5
-
47
-
-
33646203680
-
Development of human lymphoid cells
-
Blom B, Spits H. Development of human lymphoid cells. Ann Rev Immunol 2006, 24:287-320.
-
(2006)
Ann Rev Immunol
, vol.24
, pp. 287-320
-
-
Blom, B.1
Spits, H.2
-
48
-
-
0036889162
-
T-Cell Receptor: CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques
-
10.1128/JVI.76.23.12360-12364.2002, 136863, 12414978
-
Munch J, Janardhan A, Stolte N, Stahl-Hennig C, ten Haaft P, Heeney JL, Swigut T, Kirchhoff F, Skowronski J. T-Cell Receptor: CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques. J Virol 2002, 76:12360-12364. 10.1128/JVI.76.23.12360-12364.2002, 136863, 12414978.
-
(2002)
J Virol
, vol.76
, pp. 12360-12364
-
-
Munch, J.1
Janardhan, A.2
Stolte, N.3
Stahl-Hennig, C.4
ten Haaft, P.5
Heeney, J.L.6
Swigut, T.7
Kirchhoff, F.8
Skowronski, J.9
-
49
-
-
75649136915
-
CXCR4 acts as a costimulator during thymic beta-selection
-
Trampont PC, Tosello-Trampont AC, Shen YL, Duley AK, Sutherland AE, Bender TP, Littman DR, Ravichandran KS. CXCR4 acts as a costimulator during thymic beta-selection. Nature Immunol 2009, 11:162-170.
-
(2009)
Nature Immunol
, vol.11
, pp. 162-170
-
-
Trampont, P.C.1
Tosello-Trampont, A.C.2
Shen, Y.L.3
Duley, A.K.4
Sutherland, A.E.5
Bender, T.P.6
Littman, D.R.7
Ravichandran, K.S.8
-
50
-
-
76149086153
-
Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4
-
10.1084/jem.20091430, 2812547, 20038597
-
Janas ML, Varano G, Gudmundsson K, Noda M, Nagasawa T, Turner M. Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J Exp Med 2010, 207:247-261. 10.1084/jem.20091430, 2812547, 20038597.
-
(2010)
J Exp Med
, vol.207
, pp. 247-261
-
-
Janas, M.L.1
Varano, G.2
Gudmundsson, K.3
Noda, M.4
Nagasawa, T.5
Turner, M.6
-
51
-
-
0035575775
-
Evidence for increased T cell turnover and decreased thymic output in HIV infection
-
Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA. Evidence for increased T cell turnover and decreased thymic output in HIV infection. J Immunol 2001, 167:6663-6668.
-
(2001)
J Immunol
, vol.167
, pp. 6663-6668
-
-
Douek, D.C.1
Betts, M.R.2
Hill, B.J.3
Little, S.J.4
Lempicki, R.5
Metcalf, J.A.6
Casazza, J.7
Yoder, C.8
Adelsberger, J.W.9
Stevens, R.A.10
Baseler, M.W.11
Keiser, P.12
Richman, D.D.13
Davey, R.T.14
Koup, R.A.15
-
52
-
-
33644926146
-
Modelling thymic HIV-1 Nef effects
-
10.2174/157016206775197583, 16454711
-
Stove V, Verhasselt B. Modelling thymic HIV-1 Nef effects. Curr HIV Res 2006, 4:57-64. 10.2174/157016206775197583, 16454711.
-
(2006)
Curr HIV Res
, vol.4
, pp. 57-64
-
-
Stove, V.1
Verhasselt, B.2
-
53
-
-
30444454357
-
Developmental and molecular characterization of emerging [beta]- and [gamma][delta]-selected Pre-T cells in the adult mouse thymus
-
10.1016/j.immuni.2005.11.012, 16413923
-
Taghon T, Yui MA, Pant R, Diamond RA, Rothenberg EV. Developmental and molecular characterization of emerging [beta]- and [gamma][delta]-selected Pre-T cells in the adult mouse thymus. Immunity 2006, 24:53-64. 10.1016/j.immuni.2005.11.012, 16413923.
-
(2006)
Immunity
, vol.24
, pp. 53-64
-
-
Taghon, T.1
Yui, M.A.2
Pant, R.3
Diamond, R.A.4
Rothenberg, E.V.5
-
54
-
-
33646552033
-
Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse
-
10.1016/j.immuni.2006.02.016, 16713973
-
Thoulouze MI, Sol-Foulon N, Blanchet F, Dautry-Varsat A, Schwartz O, Alcover A. Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse. Immunity 2006, 24:547-561. 10.1016/j.immuni.2006.02.016, 16713973.
-
(2006)
Immunity
, vol.24
, pp. 547-561
-
-
Thoulouze, M.I.1
Sol-Foulon, N.2
Blanchet, F.3
Dautry-Varsat, A.4
Schwartz, O.5
Alcover, A.6
-
55
-
-
84856077084
-
HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling
-
10.1182/blood-2011-08-373209, 22123847
-
Pan XY, Rudolph JM, Abraham L, Habermann A, Haller C, Krijnse-Locker J, Fackler OT. HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling. Blood 2012, 119:786-797. 10.1182/blood-2011-08-373209, 22123847.
-
(2012)
Blood
, vol.119
, pp. 786-797
-
-
Pan, X.Y.1
Rudolph, J.M.2
Abraham, L.3
Habermann, A.4
Haller, C.5
Krijnse-Locker, J.6
Fackler, O.T.7
-
56
-
-
84864822218
-
HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation
-
10.4049/jimmunol.1200652, 22802418
-
Abraham L, Bankhead P, Pan XY, Engel U, Fackler OT. HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation. J Immunol 2012, 189:1898-1910. 10.4049/jimmunol.1200652, 22802418.
-
(2012)
J Immunol
, vol.189
, pp. 1898-1910
-
-
Abraham, L.1
Bankhead, P.2
Pan, X.Y.3
Engel, U.4
Fackler, O.T.5
-
57
-
-
84884248064
-
Lck availability during thymic selection determines the recognition specificity of the T cell repertoire
-
10.1016/j.cell.2013.08.009, 24034254
-
Van Laethem F, Tikhonova AN, Pobezinsky LA, Tai X, Kimura MY, Le Saout C, Guinter TI, Adams A, Sharrow SO, Bernhardt G, Feigenbaum L, Singer A. Lck availability during thymic selection determines the recognition specificity of the T cell repertoire. Cell 2013, 154:1326-1341. 10.1016/j.cell.2013.08.009, 24034254.
-
(2013)
Cell
, vol.154
, pp. 1326-1341
-
-
Van Laethem, F.1
Tikhonova, A.N.2
Pobezinsky, L.A.3
Tai, X.4
Kimura, M.Y.5
Le Saout, C.6
Guinter, T.I.7
Adams, A.8
Sharrow, S.O.9
Bernhardt, G.10
Feigenbaum, L.11
Singer, A.12
-
58
-
-
77958125069
-
HIV-1 Nef disrupts maturation of CD4(+) T cells through CD4/Lck modulation
-
10.4049/jimmunol.1001064, 20826747
-
Chrobak P, Simard MC, Bouchard N, Ndolo TM, Guertin J, Hanna Z, Dave V, Jolicoeur P. HIV-1 Nef disrupts maturation of CD4(+) T cells through CD4/Lck modulation. J Immunol 2010, 185:3948-3959. 10.4049/jimmunol.1001064, 20826747.
-
(2010)
J Immunol
, vol.185
, pp. 3948-3959
-
-
Chrobak, P.1
Simard, M.C.2
Bouchard, N.3
Ndolo, T.M.4
Guertin, J.5
Hanna, Z.6
Dave, V.7
Jolicoeur, P.8
-
59
-
-
0031962626
-
Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro
-
Verhasselt B, De Smedt M, Verhelst R, Naessens E, Plum J. Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro. Blood 1998, 91:431-440.
-
(1998)
Blood
, vol.91
, pp. 431-440
-
-
Verhasselt, B.1
De Smedt, M.2
Verhelst, R.3
Naessens, E.4
Plum, J.5
|