-
1
-
-
0034614621
-
Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5
-
An, S., Zheng, Y., and Bleu, T. (2000) Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. J. Biol. Chem. 275, 288-296
-
(2000)
J. Biol. Chem
, vol.275
, pp. 288-296
-
-
An, S.1
Zheng, Y.2
Bleu, T.3
-
2
-
-
0028956049
-
Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate
-
Goodemote, K. A., Mattie, M. E., Berger, A., and Spiegel, S. (1995) Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate. J. Biol. Chem. 270, 10272-10277
-
(1995)
J. Biol. Chem
, vol.270
, pp. 10272-10277
-
-
Goodemote, K.A.1
Mattie, M.E.2
Berger, A.3
Spiegel, S.4
-
3
-
-
0029810808
-
Structural requirements of sphingosylphosphocholine and sphingosine-1-phosphate for stimulation of activator protein-1 activity
-
Berger, A., Bittman, R., Schmidt, R. R., and Spiegel, S. (1996) Structural requirements of sphingosylphosphocholine and sphingosine-1-phosphate for stimulation of activator protein-1 activity. Mol. Pharmacol. 50, 451-457
-
(1996)
Mol. Pharmacol
, vol.50
, pp. 451-457
-
-
Berger, A.1
Bittman, R.2
Schmidt, R.R.3
Spiegel, S.4
-
4
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
Mandala, S., Hajdu, R., Bergstrom, J., Quackenbush, E., Xie, J., Milligan, J., Thornton, R., Shei, G. J., Card, D., Keohane, C., Rosenbach, M., Hale, J., Lynch, C. L., Rupprecht, K., Parsons, W., and Rosen, H. (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296, 346-349
-
(2002)
Science
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
Thornton, R.7
Shei, G.J.8
Card, D.9
Keohane, C.10
Rosenbach, M.11
Hale, J.12
Lynch, C.L.13
Rupprecht, K.14
Parsons, W.15
Rosen, H.16
-
5
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P. G., Coso, O. A., Gutkind, S., and Spiegel, S. (1996) Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381, 800-803
-
(1996)
Nature
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
Vanek, P.G.4
Coso, O.A.5
Gutkind, S.6
Spiegel, S.7
-
6
-
-
0033558079
-
Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax
-
Goetzl, E. J., Kong, Y., and Mei, B. (1999) Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. J. Immunol. 162, 2049-2056
-
(1999)
J. Immunol
, vol.162
, pp. 2049-2056
-
-
Goetzl, E.J.1
Kong, Y.2
Mei, B.3
-
7
-
-
0029027589
-
Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells. Spatial and temporal modulation of PDGF chemotactic signal transduction
-
Bornfeldt, K. E., Graves, L. M., Raines, E. W., Igarashi, Y., Wayman, G., Yamamura, S., Yatomi, Y., Sidhu, J. S., Krebs, E. G., Hakomori, S., and Ross, R. (1995) Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells. Spatial and temporal modulation of PDGF chemotactic signal transduction. J. Cell Biol. 130, 193-206
-
(1995)
J. Cell Biol
, vol.130
, pp. 193-206
-
-
Bornfeldt, K.E.1
Graves, L.M.2
Raines, E.W.3
Igarashi, Y.4
Wayman, G.5
Yamamura, S.6
Yatomi, Y.7
Sidhu, J.S.8
Krebs, E.G.9
Hakomori, S.10
Ross, R.11
-
8
-
-
0026774525
-
Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness
-
Sadahira, Y., Ruan, F., Hakomori, S., and Igarashi, Y. (1992) Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness. Proc. Natl. Acad. Sci. U.S.A. 89, 9686-9690
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 9686-9690
-
-
Sadahira, Y.1
Ruan, F.2
Hakomori, S.3
Igarashi, Y.4
-
9
-
-
58749094798
-
Sphingosine-1- phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61
-
Young, N., Pearl, D. K., and Van Brocklyn, J. R. (2009) Sphingosine-1- phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61. Mol Cancer Res. 7, 23-32
-
(2009)
Mol Cancer Res
, vol.7
, pp. 23-32
-
-
Young, N.1
Pearl, D.K.2
Van Brocklyn, J.R.3
-
10
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
Lee, M. J., Van Brocklyn, J. R., Thangada, S., Liu, C. H., Hand, A. R., Menzeleev, R., Spiegel, S., and Hla, T. (1998) Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279, 1552-1555
-
(1998)
Science
, vol.279
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brocklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
Menzeleev, R.6
Spiegel, S.7
Hla, T.8
-
11
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphingosine- 1-phosphate
-
Hait, N. C., Allegood, J., Maceyka, M., Strub, G. M., Harikumar, K. B., Singh, S. K., Luo, C., Marmorstein, R., Kordula, T., Milstien, S., and Spiegel, S. (2009) Regulation of histone acetylation in the nucleus by sphingosine- 1-phosphate. Science 325, 1254-1257
-
(2009)
Science
, vol.325
, pp. 1254-1257
-
-
Hait, N.C.1
Allegood, J.2
Maceyka, M.3
Strub, G.M.4
Harikumar, K.B.5
Singh, S.K.6
Luo, C.7
Marmorstein, R.8
Kordula, T.9
Milstien, S.10
Spiegel, S.11
-
12
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez, S. E., Harikumar, K. B., Hait, N. C., Allegood, J., Strub, G. M., Kim, E. Y., Maceyka, M., Jiang, H., Luo, C., Kordula, T., Milstien, S., and Spiegel, S. (2010) Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465, 1084-1088
-
(2010)
Nature
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
Maceyka, M.7
Jiang, H.8
Luo, C.9
Kordula, T.10
Milstien, S.11
Spiegel, S.12
-
13
-
-
0032429270
-
Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate
-
An, S., Goetzl, E. J., and Lee, H. (1998) Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate. J. Cell. Biochem. Suppl. 30-31, 147-157
-
(1998)
J. Cell. Biochem. Suppl
, vol.30-31
, pp. 147-157
-
-
An, S.1
Goetzl, E.J.2
Lee, H.3
-
14
-
-
0032031519
-
Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1
-
Zondag, G. C., Postma, F. R., Etten, I. V., Verlaan, I., and Moolenaar, W. H. (1998) Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. Biochem. J. 330, 605-609
-
(1998)
Biochem. J
, vol.330
, pp. 605-609
-
-
Zondag, G.C.1
Postma, F.R.2
Etten, I.V.3
Verlaan, I.4
Moolenaar, W.H.5
-
15
-
-
0033615537
-
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1- phosphate
-
Lee, M. J., Thangada, S., Claffey, K. P., Ancellin, N., Liu, C. H., Kluk, M., Volpi, M., Sha'afi, R. I., and Hla, T. (1999) Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1- phosphate. Cell 99, 301-312
-
(1999)
Cell
, vol.99
, pp. 301-312
-
-
Lee, M.J.1
Thangada, S.2
Claffey, K.P.3
Ancellin, N.4
Liu, C.H.5
Kluk, M.6
Volpi, M.7
Sha'Afi, R.I.8
Hla, T.9
-
16
-
-
17944363486
-
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis
-
Lee, M. J., Thangada, S., Paik, J. H., Sapkota, G. P., Ancellin, N., Chae, S. S., Wu, M., Morales-Ruiz, M., Sessa, W. C., Alessi, D. R., and Hla, T. (2001) Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol. Cell 8, 693-704
-
(2001)
Mol. Cell
, vol.8
, pp. 693-704
-
-
Lee, M.J.1
Thangada, S.2
Paik, J.H.3
Sapkota, G.P.4
Ancellin, N.5
Chae, S.S.6
Wu, M.7
Morales-Ruiz, M.8
Sessa, W.C.9
Alessi, D.R.10
Hla, T.11
-
17
-
-
58149483374
-
Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature
-
Lee, J. F., Gordon, S., Estrada, R., Wang, L., Siow, D. L., Wattenberg, B. W., Lominadze, D., and Lee, M. J. (2009) Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature. Am. J. Physiol. Heart Circ. Physiol. 296, H33-H42
-
(2009)
Am. J. Physiol. Heart Circ. Physiol
, vol.296
-
-
Lee, J.F.1
Gordon, S.2
Estrada, R.3
Wang, L.4
Siow, D.L.5
Wattenberg, B.W.6
Lominadze, D.7
Lee, M.J.8
-
18
-
-
57649194902
-
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells
-
Estrada, R., Zeng, Q., Lu, H., Sarojini, H., Lee, J. F., Mathis, S. P., Sanchez, T., Wang, E., Kontos, C. D., Lin, C. Y., Hla, T., Haribabu, B., and Lee, M. J. (2008) Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. J. Biol. Chem. 283, 30363-30375
-
(2008)
J. Biol. Chem
, vol.283
, pp. 30363-30375
-
-
Estrada, R.1
Zeng, Q.2
Lu, H.3
Sarojini, H.4
Lee, J.F.5
Mathis, S.P.6
Sanchez, T.7
Wang, E.8
Kontos, C.D.9
Lin, C.Y.10
Hla, T.11
Haribabu, B.12
Lee, M.J.13
-
19
-
-
78650866759
-
Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis
-
Skoura, A., Michaud, J., Im, D. S., Thangada, S., Xiong, Y., Smith, J. D., and Hla, T. (2011) Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 31, 81-85
-
(2011)
Arterioscler. Thromb. Vasc. Biol
, vol.31
, pp. 81-85
-
-
Skoura, A.1
Michaud, J.2
Im, D.S.3
Thangada, S.4
Xiong, Y.5
Smith, J.D.6
Hla, T.7
-
20
-
-
34347250824
-
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells. Role of lipid phosphate phosphatase-1 and sphingosine kinase 1
-
Zhao, Y., Kalari, S. K., Usatyuk, P. V., Gorshkova, I., He, D., Watkins, T., Brindley, D. N., Sun, C., Bittman, R., Garcia, J. G., Berdyshev, E. V., and Natarajan, V. (2007) Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells. Role of lipid phosphate phosphatase-1 and sphingosine kinase 1. J. Biol. Chem. 282, 14165-14177
-
(2007)
J. Biol. Chem
, vol.282
, pp. 14165-14177
-
-
Zhao, Y.1
Kalari, S.K.2
Usatyuk, P.V.3
Gorshkova, I.4
He, D.5
Watkins, T.6
Brindley, D.N.7
Sun, C.8
Bittman, R.9
Garcia, J.G.10
Berdyshev, E.V.11
Natarajan, V.12
-
21
-
-
0242710592
-
Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of Gprotein- coupled receptors
-
Meyer zu Heringdorf, D., Liliom, K., Schaefer, M., Danneberg, K., Jaggar, J. H., Tigyi, G., and Jakobs, K. H. (2003) Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of Gprotein- coupled receptors. FEBS Lett. 554, 443-449
-
(2003)
FEBS Lett
, vol.554
, pp. 443-449
-
-
Meyer Zu Heringdorf, D.1
Liliom, K.2
Schaefer, M.3
Danneberg, K.4
Jaggar, J.H.5
Tigyi, G.6
Jakobs, K.H.7
-
22
-
-
17344394207
-
Dual actions of sphingosine-1-phosphate: Extracellular through the Gi-coupled orphan receptor EDG-1 and intracellular to regulate proliferation and survival
-
Van Brocklyn, J. R., Lee, M. J., Menzeleev, R., Olivera, A., Edsall, L., Cuvillier, O., Thomas, D. M., Coopman, P. J., Thangada, S., Liu, C. H., Hla, T., and Spiegel, S. (1998) Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled orphan receptor EDG-1 and intracellular to regulate proliferation and survival. J. Cell Biol. 142, 229-240
-
(1998)
J. Cell Biol
, vol.142
, pp. 229-240
-
-
Van Brocklyn, J.R.1
Lee, M.J.2
Menzeleev, R.3
Olivera, A.4
Edsall, L.5
Cuvillier, O.6
Thomas, D.M.7
Coopman, P.J.8
Thangada, S.9
Liu, C.H.10
Hla, T.11
Spiegel, S.12
-
23
-
-
84861763037
-
ETS transcription factors and prostate cancer. The role of the family prototype ETS-1 (review)
-
Shaikhibrahim, Z., and Wernert, N. (2012) ETS transcription factors and prostate cancer. The role of the family prototype ETS-1 (review). Int. J. Oncol. 40, 1748-1754
-
(2012)
Int. J. Oncol
, vol.40
, pp. 1748-1754
-
-
Shaikhibrahim, Z.1
Wernert, N.2
-
24
-
-
0035860831
-
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration
-
Kluk, M. J., and Hla, T. (2001) Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. Circ. Res. 89, 496-502
-
(2001)
Circ. Res
, vol.89
, pp. 496-502
-
-
Kluk, M.J.1
Hla, T.2
-
25
-
-
0034462185
-
Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3
-
Okamoto, H., Takuwa, N., Yokomizo, T., Sugimoto, N., Sakurada, S., Shigematsu, H., and Takuwa, Y. (2000) Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. Mol. Cell. Biol. 20, 9247-9261
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 9247-9261
-
-
Okamoto, H.1
Takuwa, N.2
Yokomizo, T.3
Sugimoto, N.4
Sakurada, S.5
Shigematsu, H.6
Takuwa, Y.7
-
26
-
-
0033783522
-
Edg-1, theGprotein-coupled receptor for sphingosine- 1-phosphate, is essential for vascular maturation
-
Liu, Y., Wada, R., Yamashita, T., Mi, Y., Deng, C. X., Hobson, J. P., Rosenfeldt, H. M., Nava, V. E., Chae, S. S., Lee, M. J., Liu, C. H., Hla, T., Spiegel, S., and Proia, R. L. (2000) Edg-1, theGprotein-coupled receptor for sphingosine- 1-phosphate, is essential for vascular maturation. J. Clin. Invest. 106, 951-961
-
(2000)
J. Clin. Invest
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.X.5
Hobson, J.P.6
Rosenfeldt, H.M.7
Nava, V.E.8
Chae, S.S.9
Lee, M.J.10
Liu, C.H.11
Hla, T.12
Spiegel, S.13
Proia, R.L.14
-
27
-
-
36248956701
-
Finding a way out. Lymphocyte egress from lymphoid organs
-
Schwab, S. R., and Cyster, J. G. (2007) Finding a way out. Lymphocyte egress from lymphoid organs. Nat. Immunol. 8, 1295-1301
-
(2007)
Nat. Immunol
, vol.8
, pp. 1295-1301
-
-
Schwab, S.R.1
Cyster, J.G.2
-
28
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., Brinkmann, V., Allende, M. L., Proia, R. L., and Cyster, J. G. (2004) Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427, 355-360
-
(2004)
Nature
, vol.427
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
Lesneski, M.J.4
Xu, Y.5
Brinkmann, V.6
Allende, M.L.7
Proia, R.L.8
Cyster, J.G.9
-
29
-
-
70849086174
-
FTY720 (fingolimod) in multiple sclerosis. Therapeutic effects in the immune and the central nervous system
-
Brinkmann, V. (2009) FTY720 (fingolimod) in multiple sclerosis. Therapeutic effects in the immune and the central nervous system. Br J. Pharmacol. 158, 1173-1182
-
(2009)
Br J. Pharmacol
, vol.158
, pp. 1173-1182
-
-
Brinkmann, V.1
-
30
-
-
79953698725
-
HDL and sphingosine-1- phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion
-
Sekine, Y., Suzuki, K., and Remaley, A. T. (2011) HDL and sphingosine-1- phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion. Prostate 71, 690-699
-
(2011)
Prostate
, vol.71
, pp. 690-699
-
-
Sekine, Y.1
Suzuki, K.2
Remaley, A.T.3
-
31
-
-
84855544340
-
Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma
-
Bao, M., Chen, Z., Xu, Y., Zhao, Y., Zha, R., Huang, S., Liu, L., Chen, T., Li, J., Tu, H., and He, X. (2012) Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma. Liver Int. 32, 331-338
-
(2012)
Liver Int
, vol.32
, pp. 331-338
-
-
Bao, M.1
Chen, Z.2
Xu, Y.3
Zhao, Y.4
Zha, R.5
Huang, S.6
Liu, L.7
Chen, T.8
Li, J.9
Tu, H.10
He, X.11
-
32
-
-
0035853689
-
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of αvβ3- and β1-containing integrins
-
Paik, J. H., Chae, S., Lee, M. J., Thangada, S., and Hla, T. (2001) Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of αvβ3- and β1-containing integrins. J. Biol. Chem. 276, 11830-11837
-
(2001)
J. Biol. Chem
, vol.276
, pp. 11830-11837
-
-
Paik, J.H.1
Chae, S.2
Lee, M.J.3
Thangada, S.4
Hla, T.5
-
33
-
-
79960301614
-
Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Gαq coupling
-
Kim, E. S., Kim, J. S., Kim, S. G., Hwang, S., Lee, C. H., and Moon, A. (2011) Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Gαq coupling. J. Cell Sci. 124, 2220-2230
-
(2011)
J. Cell Sci
, vol.124
, pp. 2220-2230
-
-
Kim, E.S.1
Kim, J.S.2
Kim, S.G.3
Hwang, S.4
Lee, C.H.5
Moon, A.6
-
34
-
-
77749245824
-
S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development
-
Donovan, E. E., Pelanda, R., and Torres, R. M. (2010) S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development. Eur. J. Immunol. 40, 688-698
-
(2010)
Eur. J. Immunol
, vol.40
, pp. 688-698
-
-
Donovan, E.E.1
Pelanda, R.2
Torres, R.M.3
-
35
-
-
73549109212
-
Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis
-
Li, C., Jiang, X., Yang, L., Liu, X., Yue, S., and Li, L. (2009) Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis. Am. J. Pathol. 175, 1464-1472
-
(2009)
Am. J. Pathol
, vol.175
, pp. 1464-1472
-
-
Li, C.1
Jiang, X.2
Yang, L.3
Liu, X.4
Yue, S.5
Li, L.6
-
36
-
-
41649094810
-
Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation
-
Niessen, F., Schaffner, F., Furlan-Freguia, C., Pawlinski, R., Bhattacharjee, G., Chun, J., Derian, C. K., Andrade-Gordon, P., Rosen, H., and Ruf, W. (2008) Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. Nature 452, 654-658
-
(2008)
Nature
, vol.452
, pp. 654-658
-
-
Niessen, F.1
Schaffner, F.2
Furlan-Freguia, C.3
Pawlinski, R.4
Bhattacharjee, G.5
Chun, J.6
Derian, C.K.7
Andrade-Gordon, P.8
Rosen, H.9
Ruf, W.10
-
37
-
-
37349013401
-
Follicular shuttling of marginal zone B cells facilitates antigen transport
-
Cinamon, G., Zachariah, M. A., Lam, O. M., Foss, F. W., Jr., and Cyster, J. G. (2008) Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat. Immunol. 9, 54-62
-
(2008)
Nat. Immunol
, vol.9
, pp. 54-62
-
-
Cinamon, G.1
Zachariah, M.A.2
Lam, O.M.3
Foss Jr., F.W.4
Cyster, J.G.5
-
38
-
-
0038785578
-
High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors
-
Kimura, T., Sato, K., Malchinkhuu, E., Tomura, H., Tamama, K., Kuwabara, A., Murakami, M., and Okajima, F. (2003) High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors. Arterioscler. Thromb. Vasc. Biol. 23, 1283-1288
-
(2003)
Arterioscler. Thromb. Vasc. Biol
, vol.23
, pp. 1283-1288
-
-
Kimura, T.1
Sato, K.2
Malchinkhuu, E.3
Tomura, H.4
Tamama, K.5
Kuwabara, A.6
Murakami, M.7
Okajima, F.8
-
39
-
-
84860293201
-
Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells
-
Hsu, A., Zhang, W., Lee, J. F., An, J., Ekambaram, P., Liu, J., Honn, K. V., Klinge, C. M., and Lee, M. J. (2012) Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. Int. J. Oncol. 40, 1619-1626
-
(2012)
Int. J. Oncol
, vol.40
, pp. 1619-1626
-
-
Hsu, A.1
Zhang, W.2
Lee, J.F.3
An, J.4
Ekambaram, P.5
Liu, J.6
Honn, K.V.7
Klinge, C.M.8
Lee, M.J.9
-
40
-
-
79960679626
-
Identification of the orphan G proteincoupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetra-enoic acid
-
Guo, Y., Zhang, W., Giroux, C., Cai, Y., Ekambaram, P., Dilly, A. K., Hsu, A., Zhou, S., Maddipati, K. R., Liu, J., Joshi, S., Tucker, S. C., Lee, M. J., and Honn, K. V. (2011) Identification of the orphan G proteincoupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetra-enoic acid. J. Biol. Chem. 286, 33832-33840
-
(2011)
J. Biol. Chem
, vol.286
, pp. 33832-33840
-
-
Guo, Y.1
Zhang, W.2
Giroux, C.3
Cai, Y.4
Ekambaram, P.5
Dilly, A.K.6
Hsu, A.7
Zhou, S.8
Maddipati, K.R.9
Liu, J.10
Joshi, S.11
Tucker, S.C.12
Lee, M.J.13
Honn, K.V.14
-
41
-
-
34548012848
-
The let-7 microRNA represses cell proliferation pathways in human cells
-
Johnson, C. D., Esquela-Kerscher, A., Stefani, G., Byrom, M., Kelnar, K., Ovcharenko, D., Wilson, M., Wang, X., Shelton, J., Shingara, J., Chin, L., Brown, D., and Slack, F. J. (2007) The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 67, 7713-7722
-
(2007)
Cancer Res
, vol.67
, pp. 7713-7722
-
-
Johnson, C.D.1
Esquela-Kerscher, A.2
Stefani, G.3
Byrom, M.4
Kelnar, K.5
Ovcharenko, D.6
Wilson, M.7
Wang, X.8
Shelton, J.9
Shingara, J.10
Chin, L.11
Brown, D.12
Slack, F.J.13
-
42
-
-
77955022405
-
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
-
Wiggins, J. F., Ruffino, L., Kelnar, K., Omotola, M., Patrawala, L., Brown, D., and Bader, A. G. (2010) Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res. 70, 5923-5930
-
(2010)
Cancer Res
, vol.70
, pp. 5923-5930
-
-
Wiggins, J.F.1
Ruffino, L.2
Kelnar, K.3
Omotola, M.4
Patrawala, L.5
Brown, D.6
Bader, A.G.7
-
43
-
-
0032768970
-
CD44 cell adhesion molecules
-
Goodison, S., Urquidi, V., and Tarin, D. (1999) CD44 cell adhesion molecules. Mol. Pathol. 52, 189-196
-
(1999)
Mol. Pathol
, vol.52
, pp. 189-196
-
-
Goodison, S.1
Urquidi, V.2
Tarin, D.3
-
44
-
-
0342906190
-
Interaction between CD44 and the repeat domain of ankyrin promotes hyaluronic acid-mediated ovarian tumor cell migration
-
Zhu, D., and Bourguignon, L. Y. (2000) Interaction between CD44 and the repeat domain of ankyrin promotes hyaluronic acid-mediated ovarian tumor cell migration. J. Cell. Physiol. 183, 182-195
-
(2000)
J. Cell. Physiol
, vol.183
, pp. 182-195
-
-
Zhu, D.1
Bourguignon, L.Y.2
-
45
-
-
0026670584
-
CD44H regulates tumor cell migration on hyaluronate-coated substrate
-
Thomas, L., Byers, H. R., Vink, J., and Stamenkovic, I. (1992) CD44H regulates tumor cell migration on hyaluronate-coated substrate. J. Cell Biol. 118, 971-977
-
(1992)
J. Cell Biol
, vol.118
, pp. 971-977
-
-
Thomas, L.1
Byers, H.R.2
Vink, J.3
Stamenkovic, I.4
-
46
-
-
67349246260
-
Activity and intracellular location of estrogen receptors α and β in human bronchial epithelial cells
-
Ivanova, M. M., Mazhawidza, W., Dougherty, S. M., Minna, J. D., and Klinge, C. M. (2009) Activity and intracellular location of estrogen receptors α and β in human bronchial epithelial cells. Mol. Cell. Endocrinol. 305, 12-21
-
(2009)
Mol. Cell. Endocrinol
, vol.305
, pp. 12-21
-
-
Ivanova, M.M.1
Mazhawidza, W.2
Dougherty, S.M.3
Minna, J.D.4
Klinge, C.M.5
-
47
-
-
10844284696
-
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
-
Ramirez, R. D., Sheridan, S., Girard, L., Sato, M., Kim, Y., Pollack, J., Peyton, M., Zou, Y., Kurie, J. M., Dimaio, J. M., Milchgrub, S., Smith, A. L., Souza, R. F., Gilbey, L., Zhang, X., Gandia, K., Vaughan, M. B., Wright, W. E., Gazdar, A. F., Shay, J. W., and Minna, J. D. (2004) Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 64, 9027-9034
-
(2004)
Cancer Res
, vol.64
, pp. 9027-9034
-
-
Ramirez, R.D.1
Sheridan, S.2
Girard, L.3
Sato, M.4
Kim, Y.5
Pollack, J.6
Peyton, M.7
Zou, Y.8
Kurie, J.M.9
Dimaio, J.M.10
Milchgrub, S.11
Smith, A.L.12
Souza, R.F.13
Gilbey, L.14
Zhang, X.15
Gandia, K.16
Vaughan, M.B.17
Wright, W.E.18
Gazdar, A.F.19
Shay, J.W.20
Minna, J.D.21
more..
-
48
-
-
84867713914
-
Sphingosine- 1-phosphate signaling in physiology and diseases
-
Takuwa, Y., Okamoto, Y., Yoshioka, K., and Takuwa, N. (2012) Sphingosine- 1-phosphate signaling in physiology and diseases. BioFactors 38, 329-337
-
(2012)
BioFactors
, vol.38
, pp. 329-337
-
-
Takuwa, Y.1
Okamoto, Y.2
Yoshioka, K.3
Takuwa, N.4
-
49
-
-
34948819302
-
Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways
-
Brizuela, L., Rábano, M., Gangoiti, P., Narbona, N., Macarulla, J. M., Trueba, M., and Gómez-Muñoz, A. (2007) Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways. J. Lipid Res. 48, 2264-2274
-
(2007)
J. Lipid Res
, vol.48
, pp. 2264-2274
-
-
Brizuela, L.1
Rábano, M.2
Gangoiti, P.3
Narbona, N.4
Macarulla, J.M.5
Trueba, M.6
Gómez-Muñoz, A.7
-
50
-
-
77954330306
-
An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival
-
Blom, T., Bergelin, N., Meinander, A., Löf, C., Slotte, J. P., Eriksson, J. E., and Törnquist, K. (2010) An autocrine sphingosine-1- phosphate signaling loop enhances NF-κB-activation and survival. BMC Cell Biol. 11, 45
-
(2010)
BMC Cell Biol
, vol.11
, pp. 45
-
-
Blom, T.1
Bergelin, N.2
Meinander, A.3
Löf, C.4
Slotte, J.P.5
Eriksson, J.E.6
Törnquist, K.7
-
51
-
-
33750567966
-
Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphateinduced mobilization of marrow-derived stromal cells
-
Meriane, M., Duhamel, S., Lejeune, L., Galipeau, J., and Annabi, B. (2006) Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphateinduced mobilization of marrow-derived stromal cells. Stem Cells 24, 2557-2565
-
(2006)
Stem Cells
, vol.24
, pp. 2557-2565
-
-
Meriane, M.1
Duhamel, S.2
Lejeune, L.3
Galipeau, J.4
Annabi, B.5
-
52
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu, C., Kelnar, K., Liu, B., Chen, X., Calhoun-Davis, T., Li, H., Patrawala, L., Yan, H., Jeter, C., Honorio, S., Wiggins, J. F., Bader, A. G., Fagin, R., Brown, D., and Tang, D. G. (2011) The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med. 17, 211-215
-
(2011)
Nat. Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
Chen, X.4
Calhoun-Davis, T.5
Li, H.6
Patrawala, L.7
Yan, H.8
Jeter, C.9
Honorio, S.10
Wiggins, J.F.11
Bader, A.G.12
Fagin, R.13
Brown, D.14
Tang, D.G.15
-
53
-
-
0033976586
-
TRANSFAC. An integrated system for gene expression regulation
-
Wingender, E., Chen, X., Hehl, R., Karas, H., Liebich, I., Matys, V., Meinhardt, T., Prüss, M., Reuter, I., and Schacherer, F. (2000) TRANSFAC. An integrated system for gene expression regulation. Nucleic Acids Res. 28, 316-319
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 316-319
-
-
Wingender, E.1
Chen, X.2
Hehl, R.3
Karas, H.4
Liebich, I.5
Matys, V.6
Meinhardt, T.7
Prüss, M.8
Reuter, I.9
Schacherer, F.10
-
54
-
-
0030978034
-
Inhibition of vascular endothelial growth factor-induced endothelial cell migration by ETS1 antisense oligonucleotides
-
Chen, Z., Fisher, R. J., Riggs, C. W., Rhim, J. S., and Lautenberger, J. A. (1997) Inhibition of vascular endothelial growth factor-induced endothelial cell migration by ETS1 antisense oligonucleotides. Cancer Res. 57, 2013-2019
-
(1997)
Cancer Res
, vol.57
, pp. 2013-2019
-
-
Chen, Z.1
Fisher, R.J.2
Riggs, C.W.3
Rhim, J.S.4
Lautenberger, J.A.5
-
55
-
-
80052903053
-
Activin B promotes epithelial wound healing in vivo through RhoA-JNK signaling pathway
-
Zhang, M., Liu, N. Y., Wang, X. E., Chen, Y. H., Li, Q. L., Lu, K. R., Sun, L., Jia, Q., and Zhang, L. (2011) Activin B promotes epithelial wound healing in vivo through RhoA-JNK signaling pathway. PLoS One 6, e25143
-
(2011)
PLoS One
, vol.6
-
-
Zhang, M.1
Liu, N.Y.2
Wang, X.E.3
Chen, Y.H.4
Li, Q.L.5
Lu, K.R.6
Sun, L.7
Jia, Q.8
Zhang, L.9
-
56
-
-
74449089659
-
RhoA/ROCK1 signaling regulates stress granule formation and apoptosis
-
Tsai, N. P., and Wei, L. N. (2010) RhoA/ROCK1 signaling regulates stress granule formation and apoptosis. Cell Signal. 22, 668-675
-
(2010)
Cell Signal
, vol.22
, pp. 668-675
-
-
Tsai, N.P.1
Wei, L.N.2
-
57
-
-
58749101759
-
Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage
-
Ongusaha, P. P., Qi, H. H., Raj, L., Kim, Y. B., Aaronson, S. A., Davis, R. J., Shi, Y., Liao, J. K., and Lee, S. W. (2008) Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage. Sci. Signal. 1, ra14
-
(2008)
Sci. Signal
, vol.1
-
-
Ongusaha, P.P.1
Qi, H.H.2
Raj, L.3
Kim, Y.B.4
Aaronson, S.A.5
Davis, R.J.6
Shi, Y.7
Liao, J.K.8
Lee, S.W.9
-
58
-
-
80052260151
-
Acute myeloid leukemia. A central role for the ETS factor ERG
-
Martens, J. H. (2011) Acute myeloid leukemia. A central role for the ETS factor ERG. Int. J. Biochem. Cell Biol. 43, 1413-1416
-
(2011)
Int. J. Biochem. Cell Biol
, vol.43
, pp. 1413-1416
-
-
Martens, J.H.1
-
59
-
-
0034658614
-
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3
-
Kimura, T., Watanabe, T., Sato, K., Kon, J., Tomura, H., Tamama, K., Kuwabara, A., Kanda, T., Kobayashi, I., Ohta, H., Ui, M., and Okajima, F (2000) Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3. Biochem. J. 348, 71-76
-
(2000)
Biochem. J
, vol.348
, pp. 71-76
-
-
Kimura, T.1
Watanabe, T.2
Sato, K.3
Kon, J.4
Tomura, H.5
Tamama, K.6
Kuwabara, A.7
Kanda, T.8
Kobayashi, I.9
Ohta, H.10
Ui, M.11
Okajima, F.12
-
60
-
-
0037155058
-
Sphingosine-1-phosphate, a plateletderived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells
-
Ryu, Y., Takuwa, N., Sugimoto, N., Sakurada, S., Usui, S., Okamoto, H., Matsui, O., and Takuwa, Y. (2002) Sphingosine-1-phosphate, a plateletderived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells. Circ. Res. 90, 325-332
-
(2002)
Circ. Res
, vol.90
, pp. 325-332
-
-
Ryu, Y.1
Takuwa, N.2
Sugimoto, N.3
Sakurada, S.4
Usui, S.5
Okamoto, H.6
Matsui, O.7
Takuwa, Y.8
-
61
-
-
0035374461
-
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells
-
Morales-Ruiz, M., Lee, M. J., Zöllner, S., Gratton, J. P., Scotland, R., Shiojima, I., Walsh, K., Hla, T., and Sessa, W. C. (2001) Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. J. Biol. Chem. 276, 19672-19677
-
(2001)
J. Biol. Chem
, vol.276
, pp. 19672-19677
-
-
Morales-Ruiz, M.1
Lee, M.J.2
Zöllner, S.3
Gratton, J.P.4
Scotland, R.5
Shiojima, I.6
Walsh, K.7
Hla, T.8
Sessa, W.C.9
-
62
-
-
3042820790
-
Interaction of cortactin and Arp2/3 complex is required for sphingosine-1-phosphate-induced endothelial cell remodeling
-
Li, Y., Uruno, T., Haudenschild, C., Dudek, S. M., Garcia, J. G., and Zhan, X. (2004) Interaction of cortactin and Arp2/3 complex is required for sphingosine-1-phosphate-induced endothelial cell remodeling. Exp. Cell Res. 298, 107-121
-
(2004)
Exp. Cell Res
, vol.298
, pp. 107-121
-
-
Li, Y.1
Uruno, T.2
Haudenschild, C.3
Dudek, S.M.4
Garcia, J.G.5
Zhan, X.6
-
63
-
-
33749350938
-
Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity
-
Lee, J. F., Zeng, Q., Ozaki, H., Wang, L., Hand, A. R., Hla, T., Wang, E., and Lee, M. J. (2006) Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. J. Biol. Chem. 281, 29190-29200
-
(2006)
J. Biol. Chem
, vol.281
, pp. 29190-29200
-
-
Lee, J.F.1
Zeng, Q.2
Ozaki, H.3
Wang, L.4
Hand, A.R.5
Hla, T.6
Wang, E.7
Lee, M.J.8
-
64
-
-
33747307276
-
Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells
-
Lee, J. F., Ozaki, H., Zhan, X., Wang, E., Hla, T., and Lee, M. J. (2006) Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells. Histochem. Cell Biol. 126, 297-304
-
(2006)
Histochem. Cell Biol
, vol.126
, pp. 297-304
-
-
Lee, J.F.1
Ozaki, H.2
Zhan, X.3
Wang, E.4
Hla, T.5
Lee, M.J.6
-
65
-
-
42449085294
-
Rho GTPases mediated integrin αvβ3 activation in sphingosine-1-phosphate stimulated chemotaxis of endothelial cells
-
Wang, L., Lee, J. F., Lin, C. Y., and Lee, M. J. (2008) Rho GTPases mediated integrin αvβ3 activation in sphingosine-1-phosphate stimulated chemotaxis of endothelial cells. Histochem. Cell Biol. 129, 579-588
-
(2008)
Histochem. Cell Biol
, vol.129
, pp. 579-588
-
-
Wang, L.1
Lee, J.F.2
Lin, C.Y.3
Lee, M.J.4
-
66
-
-
84872846683
-
Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function
-
García-Bernal, D., Redondo-Muñoz, J., Dios-Esponera, A., Chèvre, R., Bailón, E., Garayoa, M., Arellano-Sánchez, N., Gutierrez, N. C., Hidalgo, A., García-Pardo, A., and Teixidó, J. (2013) Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function. J. Pathol. 229, 36-48
-
(2013)
J. Pathol
, vol.229
, pp. 36-48
-
-
García-Bernal, D.1
Redondo-Muñoz, J.2
Dios-Esponera, A.3
Chèvre, R.4
Bailón, E.5
Garayoa, M.6
Arellano-Sánchez, N.7
Gutierrez, N.C.8
Hidalgo, A.9
García-Pardo, A.10
Teixidó, J.11
-
67
-
-
33746786934
-
A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983
-
Gallatin, W. M., Weissman, I. L., and Butcher, E. C. (2006) A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. J. Immunol. 177, 5-9
-
(2006)
J. Immunol
, vol.177
, pp. 5-9
-
-
Gallatin, W.M.1
Weissman, I.L.2
Butcher, E.C.3
-
68
-
-
44749091840
-
Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
-
Naor, D., Wallach-Dayan, S. B., Zahalka, M. A., and Sionov, R. V. (2008) Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin. Cancer Biol. 18, 260-267
-
(2008)
Semin. Cancer Biol
, vol.18
, pp. 260-267
-
-
Naor, D.1
Wallach-Dayan, S.B.2
Zahalka, M.A.3
Sionov, R.V.4
-
69
-
-
0030966842
-
CD44. Structure, function, and association with the malignant process
-
Naor, D., Sionov, R. V., and Ish-Shalom, D. (1997) CD44. Structure, function, and association with the malignant process. Adv. Cancer Res. 71, 241-319
-
(1997)
Adv. Cancer Res
, vol.71
, pp. 241-319
-
-
Naor, D.1
Sionov, R.V.2
Ish-Shalom, D.3
-
70
-
-
0033377014
-
Signal transduction via CD44. Role of plasma membrane microdomains
-
Ilangumaran, S., Borisch, B., and Hoessli, D. C. (1999) Signal transduction via CD44. Role of plasma membrane microdomains. Leuk. Lymphoma 35, 455-469
-
(1999)
Leuk. Lymphoma
, vol.35
, pp. 455-469
-
-
Ilangumaran, S.1
Borisch, B.2
Hoessli, D.C.3
-
71
-
-
0029952227
-
Hyaluronan fragments activate an NF-κB/I-κBα autoregulatory loop in murine macrophages
-
Noble, P. W., McKee, C. M., Cowman, M., and Shin, H. S. (1996) Hyaluronan fragments activate an NF-κB/I-κBα autoregulatory loop in murine macrophages. J. Exp. Med. 183, 2373-2378
-
(1996)
J. Exp. Med
, vol.183
, pp. 2373-2378
-
-
Noble, P.W.1
McKee, C.M.2
Cowman, M.3
Shin, H.S.4
-
72
-
-
0029938495
-
Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro
-
Trochon, V., Mabilat, C., Bertrand, P., Legrand, Y., Smadja-Joffe, F., Soria, C., Delpech, B., and Lu, H. (1996) Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro. Int. J. Cancer 66, 664-668
-
(1996)
Int. J. Cancer
, vol.66
, pp. 664-668
-
-
Trochon, V.1
Mabilat, C.2
Bertrand, P.3
Legrand, Y.4
Smadja-Joffe, F.5
Soria, C.6
Delpech, B.7
Lu, H.8
-
73
-
-
0034686511
-
Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7)
-
Wittig, B. M., Johansson, B., Zöller, M., Schwärzler, C., and Günthert, U. (2000) Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7). J. Exp. Med. 191, 2053-2064
-
(2000)
J. Exp. Med
, vol.191
, pp. 2053-2064
-
-
Wittig, B.M.1
Johansson, B.2
Zöller, M.3
Schwärzler, C.4
Günthert, U.5
-
74
-
-
32644467590
-
Osteopontin. Role in cell signaling and cancer progression
-
Rangaswami, H., Bulbule, A., and Kundu, G. C. (2006) Osteopontin. Role in cell signaling and cancer progression. Trends Cell Biol. 16, 79-87
-
(2006)
Trends Cell Biol
, vol.16
, pp. 79-87
-
-
Rangaswami, H.1
Bulbule, A.2
Kundu, G.C.3
-
75
-
-
0037227965
-
CD44. from adhesion molecules to signalling regulators
-
Ponta, H., Sherman, L., and Herrlich, P. A. (2003) CD44. From adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell Biol. 4, 33-45
-
(2003)
Nat. Rev. Mol. Cell Biol
, vol.4
, pp. 33-45
-
-
Ponta, H.1
Sherman, L.2
Herrlich, P.A.3
-
76
-
-
33947537696
-
Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells. The roles of CD44v and alternative sialofucosylated selectin ligands
-
Napier, S. L., Healy, Z. R., Schnaar, R. L., and Konstantopoulos, K. (2007) Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells. The roles of CD44v and alternative sialofucosylated selectin ligands. J. Biol. Chem. 282, 3433-3441
-
(2007)
J. Biol. Chem
, vol.282
, pp. 3433-3441
-
-
Napier, S.L.1
Healy, Z.R.2
Schnaar, R.L.3
Konstantopoulos, K.4
-
77
-
-
0035404863
-
CD44-mediated oncogenic signaling and cytoskeleton activation during mammary tumor progression
-
Bourguignon, L. Y. (2001) CD44-mediated oncogenic signaling and cytoskeleton activation during mammary tumor progression. J. Mammary Gland Biol. Neoplasia 6, 287-297
-
(2001)
J. Mammary Gland Biol. Neoplasia
, vol.6
, pp. 287-297
-
-
Bourguignon, L.Y.1
-
78
-
-
0033562994
-
Methylation of the CD44 metastasis suppressor gene in human prostate cancer
-
Lou, W., Krill, D., Dhir, R., Becich, M. J., Dong, J.-T., Frierson, H. F., Jr., Isaacs, W. B., Isaacs, J. T., and Gao, A. C. (1999) Methylation of the CD44 metastasis suppressor gene in human prostate cancer. Cancer Res. 59, 2329-2331
-
(1999)
Cancer Res
, vol.59
, pp. 2329-2331
-
-
Lou, W.1
Krill, D.2
Dhir, R.3
Becich, M.J.4
Dong, J.-T.5
Frierson Jr., H.F.6
Isaacs, W.B.7
Isaacs, J.T.8
Gao, A.C.9
-
79
-
-
84865507272
-
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer
-
Krishnamachary, B., Penet, M. F., Nimmagadda, S., Mironchik, Y., Raman, V., Solaiyappan, M., Semenza, G. L., Pomper, M. G., and Bhujwalla, Z. M. (2012) Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer. PLoS One 7, e44078
-
(2012)
PLoS One
, vol.7
-
-
Krishnamachary, B.1
Penet, M.F.2
Nimmagadda, S.3
Mironchik, Y.4
Raman, V.5
Solaiyappan, M.6
Semenza, G.L.7
Pomper, M.G.8
Bhujwalla, Z.M.9
-
80
-
-
70350534843
-
Hedgehog target genes. Mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
-
Katoh, Y., and Katoh, M. (2009) Hedgehog target genes. Mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr. Mol. Med. 9, 873-886
-
(2009)
Curr. Mol. Med
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
-
81
-
-
84866464390
-
MiR- 143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells
-
Huang, S., Guo, W., Tang, Y., Ren, D., Zou, X., and Peng, X. (2012) miR- 143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. Oncol. Rep. 28, 1831-1837
-
(2012)
Oncol. Rep
, vol.28
, pp. 1831-1837
-
-
Huang, S.1
Guo, W.2
Tang, Y.3
Ren, D.4
Zou, X.5
Peng, X.6
-
82
-
-
84862638243
-
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
-
Han, M., Liu, M., Wang, Y., Chen, X., Xu, J., Sun, Y., Zhao, L., Qu, H., Fan, Y., and Wu, C. (2012) Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One 7, e39520
-
(2012)
PLoS One
, vol.7
-
-
Han, M.1
Liu, M.2
Wang, Y.3
Chen, X.4
Xu, J.5
Sun, Y.6
Zhao, L.7
Qu, H.8
Fan, Y.9
Wu, C.10
-
83
-
-
34247621213
-
Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice
-
Higuchi, T., Bartel, F. O., Masuya, M., Deguchi, T., Henderson, K. W., Li, R., Muise-Helmericks, R. C., Kern, M. J., Watson, D. K., and Spyropoulos, D. D. (2007) Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice. Mol. Cell. Biol. 27, 3353-3366
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3353-3366
-
-
Higuchi, T.1
Bartel, F.O.2
Masuya, M.3
Deguchi, T.4
Henderson, K.W.5
Li, R.6
Muise-Helmericks, R.C.7
Kern, M.J.8
Watson, D.K.9
Spyropoulos, D.D.10
-
84
-
-
0035515347
-
The ETS-domain transcription factor family
-
Sharrocks, A. D. (2001) The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2, 827-837
-
(2001)
Nat. Rev. Mol. Cell Biol
, vol.2
, pp. 827-837
-
-
Sharrocks, A.D.1
-
85
-
-
33744487384
-
Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas
-
Okuducu, A. F., Zils, U., Michaelis, S. A., Michaelides, S., and von Deimling, A. (2006) Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas. Histopathology 48, 836-845
-
(2006)
Histopathology
, vol.48
, pp. 836-845
-
-
Okuducu, A.F.1
Zils, U.2
Michaelis, S.A.3
Michaelides, S.4
Von Deimling, A.5
-
86
-
-
55549088531
-
Ets-1 upregulates HER2-induced MMP-1 expression in breast cancer cells
-
Park, Y. H., Jung, H. H., Ahn, J. S., and Im, Y. H. (2008) Ets-1 upregulates HER2-induced MMP-1 expression in breast cancer cells. Biochem. Biophys. Res. Commun. 377, 389-394
-
(2008)
Biochem. Biophys. Res. Commun
, vol.377
, pp. 389-394
-
-
Park, Y.H.1
Jung, H.H.2
Ahn, J.S.3
Im, Y.H.4
-
87
-
-
1642540213
-
The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma
-
Rothhammer, T., Hahne, J. C., Florin, A., Poser, I., Soncin, F., Wernert, N., and Bosserhoff, A. K. (2004) The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma. Cell Mol. Life Sci. 61, 118-128
-
(2004)
Cell Mol. Life Sci
, vol.61
, pp. 118-128
-
-
Rothhammer, T.1
Hahne, J.C.2
Florin, A.3
Poser, I.4
Soncin, F.5
Wernert, N.6
Bosserhoff, A.K.7
-
88
-
-
58349117651
-
Transcriptional silencing of ETS-1 efficiently suppresses angiogenesis of pancreatic cancer
-
Lefter, L. P., Dima, S., Sunamura, M., Furukawa, T., Sato, Y., Abe, M., Chivu, M., Popescu, I., and Horii, A. (2009) Transcriptional silencing of ETS-1 efficiently suppresses angiogenesis of pancreatic cancer. Cancer Gene Ther 16, 137-148
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 137-148
-
-
Lefter, L.P.1
Dima, S.2
Sunamura, M.3
Furukawa, T.4
Sato, Y.5
Abe, M.6
Chivu, M.7
Popescu, I.8
Horii, A.9
-
89
-
-
24044501934
-
Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth
-
Hahne, J. C., Okuducu, A. F., Kaminski, A., Florin, A., Soncin, F., and Wernert, N. (2005) Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth. Oncogene 24, 5384-5388
-
(2005)
Oncogene
, vol.24
, pp. 5384-5388
-
-
Hahne, J.C.1
Okuducu, A.F.2
Kaminski, A.3
Florin, A.4
Soncin, F.5
Wernert, N.6
-
90
-
-
0028862047
-
EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor
-
Ida, K., Kobayashi, S., Taki, T., Hanada, R., Bessho, F., Yamamori, S., Sugimoto, T., Ohki, M., and Hayashi, Y. (1995) EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor. Int. J. Cancer 63, 500-504
-
(1995)
Int. J. Cancer
, vol.63
, pp. 500-504
-
-
Ida, K.1
Kobayashi, S.2
Taki, T.3
Hanada, R.4
Bessho, F.5
Yamamori, S.6
Sugimoto, T.7
Ohki, M.8
Hayashi, Y.9
|