-
1
-
-
34047251154
-
Functions of the multifaceted family of sphingosine kinases and some close relatives
-
Spiegel, S., Milstien, S. (2007) Functions of the multifaceted family of sphingosine kinases and some close relatives. J. Biol. Chem. 282, 2125-2129.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2125-2129
-
-
Spiegel, S.1
Milstien, S.2
-
2
-
-
50049122673
-
Sphingosine-1-phosphate lyase in developmental and disease: sphingolipid metabolism takes flight
-
Fyrst, H., Saba, J. (2008) Sphingosine-1-phosphate lyase in developmental and disease: sphingolipid metabolism takes flight. Biochim. Biophys. Acta. 1781, 448-458.
-
(2008)
Biochim. Biophys. Acta.
, vol.1781
, pp. 448-458
-
-
Fyrst, H.1
Saba, J.2
-
3
-
-
67649252344
-
Export and functions of sphingosine-1-phosphate
-
Kim, R. H., Takabe, K., Milstien, S., Spiegel, S. (2009) Export and functions of sphingosine-1-phosphate. Biochim. Biophys. Acta. 1791, 692-699.
-
(2009)
Biochim. Biophys. Acta.
, vol.1791
, pp. 692-699
-
-
Kim, R.H.1
Takabe, K.2
Milstien, S.3
Spiegel, S.4
-
4
-
-
58849083220
-
The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors
-
Kawahara, A., Nishi, T., Hisano, Y., Fukui, H., Yamaguchi, A., et al. (2009) The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors. Science 323, 524-527.
-
(2009)
Science
, vol.323
, pp. 524-527
-
-
Kawahara, A.1
Nishi, T.2
Hisano, Y.3
Fukui, H.4
Yamaguchi, A.5
-
5
-
-
0037162038
-
Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator?
-
Okajima, F. (2002) Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator? Biochim. Biophys. Acta. 1582, 132-137.
-
(2002)
Biochim. Biophys. Acta.
, vol.1582
, pp. 132-137
-
-
Okajima, F.1
-
6
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
Lee, M. J., Van Brocklyn, J. R., Thangada, S., Liu, C. H., Hand, A. R., et al. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279, 1552-1555.
-
Science
, vol.279
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brocklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
-
7
-
-
0032538463
-
2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition
-
2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. J. Biol. Chem. 273, 27104-27110.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27104-27110
-
-
Okamoto, H.1
Takuwa, N.2
Gonda, K.3
Okazaki, H.4
Chang, K.5
-
8
-
-
78650141494
-
International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature
-
Chun, J., Hla, T., Lynch, K. R., Spiegel, S., Moolenaar, W. H. (2010) International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature. Pharmacol. Rev. 62, 579-587.
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 579-587
-
-
Chun, J.1
Hla, T.2
Lynch, K.R.3
Spiegel, S.4
Moolenaar, W.H.5
-
9
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
Liu, Y., Wada, R., Yamashita, T., Mi, Y., Deng, C. X., et al. (2000) Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J. Clin. Invest. 106, 951-961.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.X.5
-
10
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., et al. (2004) Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427, 355-360.
-
(2004)
Nature
, vol.427
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
Lesneski, M.J.4
Xu, Y.5
-
11
-
-
2142851264
-
Lysophosphlipid receptors: signaling and biology
-
Ishii, I., Fukushima, N., Ye, X., Chun, J. (2004) Lysophosphlipid receptors: signaling and biology. 73, 321-354.
-
(2004)
, vol.73
, pp. 321-354
-
-
Ishii, I.1
Fukushima, N.2
Ye, X.3
Chun, J.4
-
12
-
-
79957610938
-
The outs and the ins of sphingosine-1-phosphate in immunity
-
Spiegel, S., Milstien, S. (2011) The outs and the ins of sphingosine-1-phosphate in immunity. Nat. Rev. Immunol. 11, 403-415.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 403-415
-
-
Spiegel, S.1
Milstien, S.2
-
13
-
-
67449138784
-
Sphingosine-1-phosphate receptor signaling in the heart
-
Means, C. K., Brown, J. H. (2009) Sphingosine-1-phosphate receptor signaling in the heart. Cardiovasc. Res. 82, 193-200.
-
(2009)
Cardiovasc. Res.
, vol.82
, pp. 193-200
-
-
Means, C.K.1
Brown, J.H.2
-
14
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
FTY720 D2201 Study Group
-
Kappos, L., Antel, J., Comi, G., Montalban, X., O'Connor, P., et al. FTY720 D2201 Study Group (2006) Oral fingolimod (FTY720) for relapsing multiple sclerosis. N. Engl. J. Med. 355, 1124-1140.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
Montalban, X.4
O'Connor, P.5
-
15
-
-
9644252866
-
Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference
-
Chae, S. S., Paik, J. H., Furneaux, H., Hla, T. (2004) Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference. J. Clin. Invest. 114, 1082-1089.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1082-1089
-
-
Chae, S.S.1
Paik, J.H.2
Furneaux, H.3
Hla, T.4
-
16
-
-
68849122050
-
Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice
-
Camerer, E., Regard, J. B., Cornelissen, I., Srinivasan, Y., Duong, D. N., et al. (2009) Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice. J. Clin. Invest. 119, 1871-1879.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1871-1879
-
-
Camerer, E.1
Regard, J.B.2
Cornelissen, I.3
Srinivasan, Y.4
Duong, D.N.5
-
17
-
-
0034608826
-
Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. Proc
-
Mandala, S. M., Thornton, R., Galve-Roperh, I., Poulton, S., Peterson, C., et al. (2000) Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. Proc. Natl. Acad. Sci. USA 97, 7859-7864.
-
(2000)
Natl. Acad. Sci. USA
, vol.97
, pp. 7859-7864
-
-
Mandala, S.M.1
Thornton, R.2
Galve-Roperh, I.3
Poulton, S.4
Peterson, C.5
-
18
-
-
0032775582
-
Structural organization of mammalian lipid phosphate phosphatases: implications for signal transduction
-
Waggoner, D. W., Xu, J., Singh, I., Jasinska, R., Zhang, Q. X., et al. (1999) Structural organization of mammalian lipid phosphate phosphatases: implications for signal transduction. Biochim. Biophys. Acta. 1439, 299-316.
-
(1999)
Biochim. Biophys. Acta.
, vol.1439
, pp. 299-316
-
-
Waggoner, D.W.1
Xu, J.2
Singh, I.3
Jasinska, R.4
Zhang, Q.X.5
-
19
-
-
10644260243
-
Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720
-
Allende, M. L., Sasaki, T., Kawai, H., Olivera, A., Mi, Y., et al. (2004) Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720. J. Biol. Chem. 279, 52487-52492.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52487-52492
-
-
Allende, M.L.1
Sasaki, T.2
Kawai, H.3
Olivera, A.4
Mi, Y.5
-
20
-
-
27744552046
-
Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720
-
Kharel, Y., Lee, S., Snyder, A. H., Sheasley-O'neill, S. L., Morris, M. A., et al. (2005) Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720. J. Biol. Chem. 280, 36865-36872.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36865-36872
-
-
Kharel, Y.1
Lee, S.2
Snyder, A.H.3
Sheasley-O'neill, S.L.4
Morris, M.A.5
-
21
-
-
58149474166
-
Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions
-
Vogel, P., Donoviel, M. S., Read, R., Hansen, G. M., Hazlewood, J., et al. (2009) Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions. PLoS One. 4, e4112.
-
(2009)
PLoS One
, vol.4
-
-
Vogel, P.1
Donoviel, M.S.2
Read, R.3
Hansen, G.M.4
Hazlewood, J.5
-
22
-
-
77951213051
-
Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver
-
Bektas, M., Allende, M. L., Lee, B. G., Chen, W., Amar, M. J., et al. (2010) Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver. J. Biol. Chem. 285, 10880-10889.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10880-10889
-
-
Bektas, M.1
Allende, M.L.2
Lee, B.G.3
Chen, W.4
Amar, M.J.5
-
23
-
-
79958257954
-
Lipid phosphate phosphatase 3 enables efficient thymic egress
-
Bréart, B., Ramos-Perez, W. D., Mendoza, A., Salous, A. K., Gobert, M., et al. (2011) Lipid phosphate phosphatase 3 enables efficient thymic egress. J. Exp. Med. 208, 1267-1278.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1267-1278
-
-
Bréart, B.1
Ramos-Perez, W.D.2
Mendoza, A.3
Salous, A.K.4
Gobert, M.5
-
24
-
-
66349086742
-
Bioactive sphingolipids: metabolism and function
-
Bartke, N., Hannun, Y. A. (2009) Bioactive sphingolipids: metabolism and function. J. Lipid Res. 50 Suppl: S91-S96.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL
-
-
Bartke, N.1
Hannun, Y.A.2
-
25
-
-
24644469502
-
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients
-
Schwab, S. R., Pereira, J. P., Matloubian, M., Xu, Y., Huang, Y., et al. (2005) Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science 309, 1735-1739.
-
(2005)
Science
, vol.309
, pp. 1735-1739
-
-
Schwab, S.R.1
Pereira, J.P.2
Matloubian, M.3
Xu, Y.4
Huang, Y.5
-
26
-
-
34247379074
-
Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate
-
Pappu, R., Schwab, S. R., Cornelissen, I., Pereira, J. P., Regard, J. B., et al. (2007) Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 316, 295-298.
-
(2007)
Science
, vol.316
, pp. 295-298
-
-
Pappu, R.1
Schwab, S.R.2
Cornelissen, I.3
Pereira, J.P.4
Regard, J.B.5
-
27
-
-
41449112571
-
Vascular endothelium as a contributor of plasma sphingosine 1-phosphate
-
Venkataraman, K., Lee, Y. M., Michaud, J., Thangada, S., Ai, Y., et al. (2008) Vascular endothelium as a contributor of plasma sphingosine 1-phosphate. Circ. Res. 102, 669-676.
-
(2008)
Circ. Res.
, vol.102
, pp. 669-676
-
-
Venkataraman, K.1
Lee, Y.M.2
Michaud, J.3
Thangada, S.4
Ai, Y.5
-
28
-
-
0033615537
-
Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
-
Lee, M. J., Thangada, S., Claffey, K. P., Ancellin, N., Liu, C. H., et al. (1999) Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell 99, 301-312.
-
(1999)
Cell
, vol.99
, pp. 301-312
-
-
Lee, M.J.1
Thangada, S.2
Claffey, K.P.3
Ancellin, N.4
Liu, C.H.5
-
29
-
-
11144356028
-
HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3
-
Nofer, J. R., van der Giet, M., Tölle, M., Wolinska, I., von Wnuck Lipinski, K., et al. (2004) HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3. J. Clin. Invest. 113, 569-581.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 569-581
-
-
Nofer, J.R.1
van der Giet, M.2
Tölle, M.3
Wolinska, I.4
von Wnuck Lipinski, K.5
-
30
-
-
0034644150
-
Sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development
-
Kupperman, E., An, S., Osborne, N., Waldron, S., Stainier, D. Y. (2000) Sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development. Nature 406, 192-195.
-
(2000)
Nature
, vol.406
, pp. 192-195
-
-
Kupperman, E.1
An, S.2
Osborne, N.3
Waldron, S.4
Stainier, D.Y.5
-
31
-
-
76549090692
-
S1P2, the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice
-
Du, W., Takuwa, N., Yoshioka, K., Okamoto, Y., Gonda, K., et al. (2010) S1P2, the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice. Cancer Res. 70, 772-781.
-
(2010)
Cancer Res.
, vol.70
, pp. 772-781
-
-
Du, W.1
Takuwa, N.2
Yoshioka, K.3
Okamoto, Y.4
Gonda, K.5
-
32
-
-
0032959716
-
The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signaling pathways
-
Gonda, K., Okamoto, H., Takuwa, N., Yatomi, Y., Okazaki, H., et al. (1999) The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signaling pathways. Biochem. J. 337, 67-75.
-
(1999)
Biochem. J.
, vol.337
, pp. 67-75
-
-
Gonda, K.1
Okamoto, H.2
Takuwa, N.3
Yatomi, Y.4
Okazaki, H.5
-
33
-
-
0033600173
-
EDG3 is a functional receptor specific for sphingosine-1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16
-
Okamoto, H., Takuwa, N., Yatomi, Y., Gonda, K., Shigematsu, H., et al. (1999) EDG3 is a functional receptor specific for sphingosine-1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16. Biochem. Biophys. Res. Commun. 260, 203-208.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.260
, pp. 203-208
-
-
Okamoto, H.1
Takuwa, N.2
Yatomi, Y.3
Gonda, K.4
Shigematsu, H.5
-
34
-
-
34249861932
-
Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
-
Jiang, L. I., Collins, J., Davis, R., Lin, K. M., DeCamp, D., et al. (2007) Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway. J. Biol. Chem. 282, 10576-10584.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10576-10584
-
-
Jiang, L.I.1
Collins, J.2
Davis, R.3
Lin, K.M.4
DeCamp, D.5
-
35
-
-
77953966511
-
Sphingosine 1-phosphate and cancer
-
Pyne, N. J., Pyne, S. (2010) Sphingosine 1-phosphate and cancer. Nat. Rev. Cancer. 10, 489-503.
-
(2010)
Nat. Rev. Cancer.
, vol.10
, pp. 489-503
-
-
Pyne, N.J.1
Pyne, S.2
-
36
-
-
84857546158
-
Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1-jekyll hidden behind Hyde
-
Takuwa, N., Du, W., Kaneko, E., Okamoto, Y., Yoshioka, K., et al. (2011) Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1-jekyll hidden behind Hyde. Am. J. Cancer Res. 1, 460-481.
-
(2011)
Am. J. Cancer Res.
, vol.1
, pp. 460-481
-
-
Takuwa, N.1
Du, W.2
Kaneko, E.3
Okamoto, Y.4
Yoshioka, K.5
-
37
-
-
0026774525
-
Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness
-
Sadahira, Y., Ruan, F., Hakomori, S., Igarashi, Y. (1992) Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness. Proc. Natl. Acad. Sci. USA 89, 9686-9690.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9686-9690
-
-
Sadahira, Y.1
Ruan, F.2
Hakomori, S.3
Igarashi, Y.4
-
38
-
-
0034462185
-
Inhibitory regulation of Rac activation, membrane ruffling and cell migration by sphingosine-1-phosphate receptor EDG5, but not EDG1 or EDG3
-
Okamoto, H., Takuwa, N., Yokomizo, T., Sugimoto, N., Sakurada, S., et al. (2000) Inhibitory regulation of Rac activation, membrane ruffling and cell migration by sphingosine-1-phosphate receptor EDG5, but not EDG1 or EDG3. Mol. Cell. Biol. 20, 9247-9261.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9247-9261
-
-
Okamoto, H.1
Takuwa, N.2
Yokomizo, T.3
Sugimoto, N.4
Sakurada, S.5
-
39
-
-
13444302479
-
Inhibition of Rac activation as a mechanism for negative regulation of actin cytoskeletal reorganization and cell motility by cyclic AMP
-
Nagasawa, S., Takuwa, N., Sugimoto, N., Mabuchi, H., Takuwa, Y. (2005) Inhibition of Rac activation as a mechanism for negative regulation of actin cytoskeletal reorganization and cell motility by cyclic AMP. Biochem. J. 385, 737-744.
-
(2005)
Biochem. J.
, vol.385
, pp. 737-744
-
-
Nagasawa, S.1
Takuwa, N.2
Sugimoto, N.3
Mabuchi, H.4
Takuwa, Y.5
-
40
-
-
15444373513
-
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
-
Sanchez, T., Thangada, S., Wu, M. T., Kontos, C. D., Wu, D., et al. (2005) PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proc. Natl. Acad. Sci. USA 102, 4312-4317.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4312-4317
-
-
Sanchez, T.1
Thangada, S.2
Wu, M.T.3
Kontos, C.D.4
Wu, D.5
-
41
-
-
49949099544
-
Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system
-
Takuwa, Y., Okamoto, Y., Yoshioka, K., Takuwa, N. (2008) Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system. Biochim. Biophys. Acta. 1781, 483-488.
-
(2008)
Biochim. Biophys. Acta.
, vol.1781
, pp. 483-488
-
-
Takuwa, Y.1
Okamoto, Y.2
Yoshioka, K.3
Takuwa, N.4
-
42
-
-
3142744111
-
The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis
-
Kono, M., Mi, Y., Liu, Y., Sasaki, T., Allende, M. L., et al. (2004) The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis. J. Biol. Chem. 279, 29367-29373.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29367-29373
-
-
Kono, M.1
Mi, Y.2
Liu, Y.3
Sasaki, T.4
Allende, M.L.5
-
43
-
-
33644830810
-
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
-
Visentin, B., Vekich, J. A., Sibbald, B. J., Cavalli, A. L., Moreno, K. M., et al. (2006) Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 9, 225-238.
-
(2006)
Cancer Cell
, vol.9
, pp. 225-238
-
-
Visentin, B.1
Vekich, J.A.2
Sibbald, B.J.3
Cavalli, A.L.4
Moreno, K.M.5
-
44
-
-
0141679087
-
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and hematogenous metastasis of melanoma cells
-
Yamaguchi, H., Kitayama, J., Takuwa, N., Arikawa, K., Inoki, I., et al. (2003) Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and hematogenous metastasis of melanoma cells. Biochem. J. 374, 715-722.
-
(2003)
Biochem. J.
, vol.374
, pp. 715-722
-
-
Yamaguchi, H.1
Kitayama, J.2
Takuwa, N.3
Arikawa, K.4
Inoki, I.5
-
45
-
-
34848892421
-
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina
-
Skoura, A., Sanchez, T., Claffey, K., Mandala, S. M., Proia, R. L., et al. (2007) Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina. J. Clin. Invest. 117, 2506-2516.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2506-2516
-
-
Skoura, A.1
Sanchez, T.2
Claffey, K.3
Mandala, S.M.4
Proia, R.L.5
-
46
-
-
72249096210
-
Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation
-
Cattoretti, G., Mandelbaum, J., Lee, N., Chaves, A. H., Mahler, A. M., et al. (2009) Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation. Cancer Res. 69, 8686-8692.
-
(2009)
Cancer Res.
, vol.69
, pp. 8686-8692
-
-
Cattoretti, G.1
Mandelbaum, J.2
Lee, N.3
Chaves, A.H.4
Mahler, A.M.5
-
47
-
-
67449152428
-
Sphingosine-1-phosphate and modulation of vascular tone
-
Igarashi, J., Michel, T. (2009) Sphingosine-1-phosphate and modulation of vascular tone. Cardiovasc. Res. 82, 212-220.
-
(2009)
Cardiovasc. Res.
, vol.82
, pp. 212-220
-
-
Igarashi, J.1
Michel, T.2
-
48
-
-
33846135087
-
Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice
-
Lorenz, J. N., Arend, L. J., Robitz, R., Paul, R. J., MacLennan, A. J. (2007) Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R440-R446.
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.292
-
-
Lorenz, J.N.1
Arend, L.J.2
Robitz, R.3
Paul, R.J.4
MacLennan, A.J.5
-
49
-
-
0034799675
-
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
-
Garcia, J. G., Liu, F., Verin, A. D., Birukova, A., Dechert, M. A., et al. (2001) Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J. Clin. Invest. 108, 689-701.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 689-701
-
-
Garcia, J.G.1
Liu, F.2
Verin, A.D.3
Birukova, A.4
Dechert, M.A.5
-
50
-
-
34249280944
-
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscler
-
Sanchez, T., Skoura, A., Wu, M. T., Casserly, B., Harrington, E. O., et al. (2007 Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscler. Thromb. Vasc. Biol. 27, 1312-1318.
-
(2007)
Thromb. Vasc. Biol.
, vol.27
, pp. 1312-1318
-
-
Sanchez, T.1
Skoura, A.2
Wu, M.T.3
Casserly, B.4
Harrington, E.O.5
-
51
-
-
77952327561
-
Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung. Am. J. Respir
-
Sammani, S., Moreno-Vinasco, L., Mirzapoiazova, T., Singleton, P. A., Chiang, E. T., et al. (2010) Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung. Am. J. Respir. Cell. Mol. Biol. 43, 394-402.
-
(2010)
Cell. Mol. Biol.
, vol.43
, pp. 394-402
-
-
Sammani, S.1
Moreno-Vinasco, L.2
Mirzapoiazova, T.3
Singleton, P.A.4
Chiang, E.T.5
-
52
-
-
65549167989
-
Differential regulation of sphingosine kinases 1 and 2 in lung injury
-
Wadgaonkar, R., Patel, V., Grinkina, N., Romano, C., Liu, J., et al. (2009) Differential regulation of sphingosine kinases 1 and 2 in lung injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 296, L603-L613.
-
(2009)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.296
-
-
Wadgaonkar, R.1
Patel, V.2
Grinkina, N.3
Romano, C.4
Liu, J.5
-
53
-
-
79957925060
-
Engagement of S1P1-degradative mechanisms leads to vascular leak in mice
-
Oo, M. L., Chang, S. H., Thangada, S., Wu, M. T., Rezaul, K., et al. (2011) Engagement of S1P1-degradative mechanisms leads to vascular leak in mice. J. Clin. Invest. 121, 2290-2300.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2290-2300
-
-
Oo, M.L.1
Chang, S.H.2
Thangada, S.3
Wu, M.T.4
Rezaul, K.5
-
54
-
-
77951817430
-
Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice
-
Olivera, A., Eisner, C., Kitamura, Y., Dillahunt, S., Allende, L., et al. (2010) Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice. J. Clin. Invest. 120, 1429-1440.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1429-1440
-
-
Olivera, A.1
Eisner, C.2
Kitamura, Y.3
Dillahunt, S.4
Allende, L.5
-
55
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez, S. E., Harikumar, K. B., Hait, N. C., Allegood, J., Strub, G. M., et al. (2010) Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465: 1084-1088.
-
(2010)
Nature
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
-
56
-
-
33847131347
-
Tipping the gatekeeper: S1P regulation of endothelial barrier function
-
Rosen, H., Sanna, M. G., Cahalan, S. M., Gonzalez-Cabrera, P. J. (2007) Tipping the gatekeeper: S1P regulation of endothelial barrier function. Trends Immunol. 28, 102-107.
-
(2007)
Trends Immunol.
, vol.28
, pp. 102-107
-
-
Rosen, H.1
Sanna, M.G.2
Cahalan, S.M.3
Gonzalez-Cabrera, P.J.4
-
57
-
-
79959377393
-
The sphingosine 1-phosphate receptor S1P maintains the homeostasis of germinal center B cells and promotes niche confinement
-
Green, J. A., Suzuki, K., Cho, B., Willison, L. D., Palmer, D., et al. (2011) The sphingosine 1-phosphate receptor S1P maintains the homeostasis of germinal center B cells and promotes niche confinement. Nat. Immunol. 12, 672-680.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 672-680
-
-
Green, J.A.1
Suzuki, K.2
Cho, B.3
Willison, L.D.4
Palmer, D.5
-
58
-
-
41649094810
-
Dendritic cell PAR1-S1P3 signaling couples coagulation and inflammation
-
Niessen, F., Schaffner, F., Furlan-Freguia, C., Pawlinski, R., Bhattacharjee, G., et al. (2008) Dendritic cell PAR1-S1P3 signaling couples coagulation and inflammation. Nature 452, 654-658.
-
(2008)
Nature
, vol.452
, pp. 654-658
-
-
Niessen, F.1
Schaffner, F.2
Furlan-Freguia, C.3
Pawlinski, R.4
Bhattacharjee, G.5
-
59
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate
-
Hait, N. C., Allegood, J., Maceyka, M., Strub, G. M., Harikumar, K. B., et al. (2009) Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science 325: 1254-1257.
-
(2009)
Science
, vol.325
, pp. 1254-1257
-
-
Hait, N.C.1
Allegood, J.2
Maceyka, M.3
Strub, G.M.4
Harikumar, K.B.5
-
60
-
-
79551648970
-
Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
-
Strub, G. M., Paillard, M., Liang, J., Gomez, L., Allegood, J. C., et al. (2011) Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration. Faseb J 25: 600-612.
-
(2011)
Faseb J
, vol.25
, pp. 600-612
-
-
Strub, G.M.1
Paillard, M.2
Liang, J.3
Gomez, L.4
Allegood, J.C.5
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