HDL and sphingosine-1-phosphate activate Stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion

Prostate

Volumn 71, Issue 7, 2011, Pages 690-699

  Sekine, Yoshitaka ^a,b   Suzuki, Kazuhiro ^b   Remaley, Alan T ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

DU145; HDL; Prostate cancer; S1P; Stat3

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; G PROTEIN COUPLED RECEPTOR; HIGH DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SERINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; STAT3 PROTEIN; TYROSINE;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL INVASION; CELL MIGRATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MALE; METASTASIS; PATHOGENESIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CELL LINE, TUMOR; CELL MOVEMENT; CHOLESTEROL, HDL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYSOPHOSPHOLIPIDS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROSTATIC NEOPLASMS; RECEPTORS, LYSOSPHINGOLIPID; RNA, MESSENGER; SPHINGOSINE; STAT3 TRANSCRIPTION FACTOR;

EID: 79953698725     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21285     Document Type: Article

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