Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function

Journal of Pathology

Volumn 229, Issue 1, 2013, Pages 36-48

  García Bernal, David ^a   Redondo Muñoz, Javier ^a   Dios Esponera, Ana ^a   Chèvre, Raphaël ^b   Bailõn, Elvira ^a   Garayoa, Mercedes ^c   Arellano Sánchez, Nohemí ^a   Gutierrez, Norma C ^d   Hidalgo, Andrés ^b   García Pardo, Angeles ^a   Teixidõ, Joaquin ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c CSIC   (Spain)

^d HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

bone marrow; cell adhesion and migration; chemokines; integrins; multiple myeloma; signalling

Indexed keywords

BETA1 INTEGRIN; CHEMOKINE; G PROTEIN COUPLED RECEPTOR; PROTEIN DOCK2; RAC1 PROTEIN; SCAFFOLD PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; STROMAL CELL DERIVED FACTOR 1; TALIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 3; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; BINDING AFFINITY; BONE MARROW; CANCER GROWTH; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CELL SPREADING; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; MICROVASCULATURE; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR UPREGULATION;

ANIMALS; BONE MARROW; CELL ADHESION; CELL SHAPE; CHEMOKINE CXCL12; COCULTURE TECHNIQUES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; INTEGRIN ALPHA4BETA1; INTEGRIN ALPHA5BETA1; K562 CELLS; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED NOD; MICE, SCID; MULTIPLE MYELOMA; RAC1 GTP-BINDING PROTEIN; RECEPTORS, LYSOSPHINGOLIPID; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPHINGOSINE; STROMAL CELLS; TALIN; TIME FACTORS; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TRANSFECTION; TUMOR CELLS, CULTURED; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84872846683     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4066     Document Type: Article

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