Bioreducible hyaluronic acid conjugates as siRNA carrier for tumor targeting

Journal of Controlled Release

Volumn 172, Issue 3, 2013, Pages 653-661

  Yoon, Hong Yeol ^a,b   Kim, Hyun Ryoung ^c   Saravanakumar, Gurusamy ^a   Heo, Roun ^a   Chae, Su Young ^c   Um, Wooram ^a   Kim, Kwangmeyung ^b   Kwon, Ick Chan ^b   Lee, Jun Young ^a   Lee, Doo Sung ^a   Park, Jae Chan ^c   Park, Jae Hyung ^a  

^a Sungkyunkwan University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Samsung Advanced Institute of Technology (SAIT)   (South Korea)

Author keywords

Bioreducible conjugate; Hyaluronic acid; siRNA; Stability; Tumor targetability

Indexed keywords

BIOREDUCIBLE CONJUGATE; CLINICAL TRANSLATION; DIMETHYLAMINOETHYL METHACRYLATES; FIBROBLAST CELLS; POLYMERIC NANOCARRIERS; SIRNA; SYSTEMIC ADMINISTRATION; TUMOR TARGETING;

CELL CULTURE; CELLS; CONVERGENCE OF NUMERICAL METHODS; COVALENT BONDS; CROSSLINKING; HYALURONIC ACID; ONCOLOGY; ORGANIC ACIDS; TUMORS;

SYNTHESIS (CHEMICAL);

DISULFIDE; HERMES ANTIGEN; HYALURONIC ACID; POLY(DIMETHYLAMINOETHYL METHACRYLATE); POLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER GENE THERAPY; CATABOLISM; CELL VIABILITY; CHEMICAL STRUCTURE; CONJUGATE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; ENDOCYTOSIS; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SURFACE CHARGE;

BIOREDUCIBLE CONJUGATE; HYALURONIC ACID; SIRNA; STABILITY; TUMOR TARGETABILITY;

ANIMALS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GENE SILENCING; HAPLORHINI; HYALURONIC ACID; MELANOMA; METHACRYLATES; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; NIH 3T3 CELLS; RNA, SMALL INTERFERING;

EID: 84887162804     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.09.008     Document Type: Article

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