Synthesis of poly(β-amino ester)s with thiol-reactive side chains for DNA delivery

Journal of the American Chemical Society

Volumn 128, Issue 39, 2006, Pages 12726-12734

  Zugates, Gregory T ^a   Anderson, Daniel G ^a   Little, Steven R ^a,b   Lawhorn, Ingrid E B ^a   Langer, Robert ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b University of Pittsburgh   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADABLE POLYMERS; INTRACELLULAR GLUTATHIONE CONCENTRATIONS; MERCAPTOETHYLAMINE (MEA); PYRIDYLDITHIO ETHYLAMINE (PDA);

AMINO ACIDS; DNA; GENETIC ENGINEERING; MONOMERS; ORGANIC POLYMERS; SYNTHESIS (CHEMICAL);

ESTERS;

ARGININE; ASPARTIC ACID; CATION; CYSTEINE; DNA; ESTER DERIVATIVE; ETHYLAMINE; GLUTATHIONE; GLYCINE; INTEGRIN RECEPTOR; LIGAND; MERCAPTAMINE; MONOMER; PLASMID DNA; POLYAMINE; PYRIDINE DERIVATIVE; THIOL DERIVATIVE;

AGAR GEL ELECTROPHORESIS; ARTICLE; BINDING AFFINITY; BIODEGRADATION; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); DNA BINDING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIGAND BINDING; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PROTEIN DNA BINDING;

BIOCOMPATIBLE MATERIALS; CARCINOMA, HEPATOCELLULAR; CYSTEAMINE; DNA; ELECTROPHORESIS, AGAR GEL; ESTERS; ETHYLAMINES; HUMANS; LIVER NEOPLASMS; POLYMERS; PYRIDINES; TRANSFECTION;

EID: 33749529741     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja061570n     Document Type: Article

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