Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment

Angewandte Chemie - International Edition

Volumn 51, Issue 29, 2012, Pages 7203-7207

  Lee, So Jin ^a   Huh, Myung Sook ^a   Lee, Seung Young ^a,b   Min, Solki ^a   Lee, Seulki ^a   Koo, Heebeom ^a   Chu, Jun Uk ^a   Lee, Kyung Eun ^a   Jeon, Hyesung ^a   Choi, Yongseok ^b   Choi, Kuiwon ^a   Byun, Youngro ^c   Jeong, Seo Young ^d   Park, Kinam ^e   Kim, Kwangmeyung ^a   Kwon, Ick Chan ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

^c Seoul National University   (South Korea)

^d Kyung Hee University   (South Korea)

^e PURDUE UNIVERSITY   (United States)

Author keywords

Antitumor agents; Glycol chitosan; Nanoparticles; Poly siRNA; SiRNA delivery

Indexed keywords

ANTI-TUMOR AGENTS; CHARGE-CHARGE INTERACTIONS; CHITOSAN NANOPARTICLES; GLYCOL CHITOSAN; IN-VIVO; POLY-SIRNA; SIRNA DELIVERY; TUMOR SIZE; VASCULARIZATION;

CHITOSAN; GLYCOLS; RNA; TUMORS;

NANOPARTICLES;

CHITOSAN; GLYCOL CHITOSAN; GLYCOL-CHITOSAN; NANOPARTICLE; SMALL INTERFERING RNA; THIOL DERIVATIVE; VASCULOTROPIN A;

ANIMAL; ARTICLE; CHEMISTRY; GENE THERAPY; GENETICS; HUMAN; MOUSE; NEOPLASM; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHITOSAN; GENE THERAPY; HUMANS; MICE; NANOPARTICLES; NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SULFHYDRYL COMPOUNDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84863848240     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201201390     Document Type: Article

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