-
1
-
-
83055186549
-
Neuronal activity regulates glutamate transporter dynamics in developing astrocytes
-
Benediktsson AM, Marrs GS, Tu JC, Worley PF, Rothstein JD, Bergles DE, Dailey ME. 2012. Neuronal activity regulates glutamate transporter dynamics in developing astrocytes. Glia 60:175-188.
-
(2012)
Glia
, vol.60
, pp. 175-188
-
-
Benediktsson, A.M.1
Marrs, G.S.2
Tu, J.C.3
Worley, P.F.4
Rothstein, J.D.5
Bergles, D.E.6
Dailey, M.E.7
-
2
-
-
34047095297
-
The two TORCs and Akt
-
Bhaskar PT, Hay N. 2007. The two TORCs and Akt. Dev Cell 12:487-502.
-
(2007)
Dev Cell
, vol.12
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
3
-
-
43049104698
-
Normobaric hyperoxia induces ischemic tolerance and upregulation of glutamate transporters in the rat brain and serum TNF-alpha level
-
Bigdeli MR, Hajizadeh S, Froozandeh M, Heidarianpour A, Rasoulian B, Asgari AR, Pourkhalili K, Khoshbaten A. 2008. Normobaric hyperoxia induces ischemic tolerance and upregulation of glutamate transporters in the rat brain and serum TNF-alpha level. Exp Neurol 212:298-306.
-
(2008)
Exp Neurol
, vol.212
, pp. 298-306
-
-
Bigdeli, M.R.1
Hajizadeh, S.2
Froozandeh, M.3
Heidarianpour, A.4
Rasoulian, B.5
Asgari, A.R.6
Pourkhalili, K.7
Khoshbaten, A.8
-
4
-
-
0028929371
-
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
-
Brockman JA, Scherer DC, McKinsey TA, Hall SM, Qi X, Lee WY, Ballard DW. 1995. Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. Mol Cell Biol 15:2809-2818.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2809-2818
-
-
Brockman, J.A.1
Scherer, D.C.2
McKinsey, T.A.3
Hall, S.M.4
Qi, X.5
Lee, W.Y.6
Ballard, D.W.7
-
5
-
-
1342308184
-
Maturation of astrocyte morphology and the establishment of astrocyte domains during postnatal hippocampal development
-
Bushong EA, Martone ME, Ellisman MH. 2004. Maturation of astrocyte morphology and the establishment of astrocyte domains during postnatal hippocampal development. Int J Dev Neurosci 22:73-86.
-
(2004)
Int J Dev Neurosci
, vol.22
, pp. 73-86
-
-
Bushong, E.A.1
Martone, M.E.2
Ellisman, M.H.3
-
6
-
-
0036139877
-
Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains
-
Bushong EA, Martone ME, Jones YZ, Ellisman MH. 2002. Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J Neurosci 22:183-192.
-
(2002)
J Neurosci
, vol.22
, pp. 183-192
-
-
Bushong, E.A.1
Martone, M.E.2
Jones, Y.Z.3
Ellisman, M.H.4
-
7
-
-
68249115320
-
Injury and repair mechanisms in ischemic stroke: Considerations for the development of novel neurotherapeutics
-
Candelario-Jalil E. 2009. Injury and repair mechanisms in ischemic stroke: Considerations for the development of novel neurotherapeutics. Curr Opin Investig Drugs 10:644-654.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 644-654
-
-
Candelario-Jalil, E.1
-
8
-
-
84863278527
-
Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes
-
Chen LL, Wu JC, Wang LH, Wang J, Qin ZH, Difiglia M, Lin F. 2012. Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes. Acta Pharmacol Sin 33:385-392.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 385-392
-
-
Chen, L.L.1
Wu, J.C.2
Wang, L.H.3
Wang, J.4
Qin, Z.H.5
Difiglia, M.6
Lin, F.7
-
9
-
-
35348820823
-
Targeting the mTOR signaling network in cancer
-
Chiang GG, Abraham RT. 2007. Targeting the mTOR signaling network in cancer. Trends Mol Med 13:433-442.
-
(2007)
Trends Mol Med
, vol.13
, pp. 433-442
-
-
Chiang, G.G.1
Abraham, R.T.2
-
10
-
-
77957596899
-
Transient cerebral ischemia induces active astrocytosis without distinct neuronal death in the gerbil main olfactory bulb: A long-term analysis
-
Choi JH, Yoo KY, Lee CH, Park O, Yan BC, Li H, Moon YS, Hwang IK, Lee YL, Shin HC, Won MH. 2010. Transient cerebral ischemia induces active astrocytosis without distinct neuronal death in the gerbil main olfactory bulb: A long-term analysis. Neurochem Res 35:1588-1598.
-
(2010)
Neurochem Res
, vol.35
, pp. 1588-1598
-
-
Choi, J.H.1
Yoo, K.Y.2
Lee, C.H.3
Park, O.4
Yan, B.C.5
Li, H.6
Moon, Y.S.7
Hwang, I.K.8
Lee, Y.L.9
Shin, H.C.10
Won, M.H.11
-
11
-
-
59649110910
-
The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord
-
Codeluppi S, Svensson CI, Hefferan MP, Valencia F, Silldorff MD, Oshiro M, Marsala M, Pasquale EB. 2009. The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. J Neurosci 29:1093-1104.
-
(2009)
J Neurosci
, vol.29
, pp. 1093-1104
-
-
Codeluppi, S.1
Svensson, C.I.2
Hefferan, M.P.3
Valencia, F.4
Silldorff, M.D.5
Oshiro, M.6
Marsala, M.7
Pasquale, E.B.8
-
12
-
-
0029990439
-
Astrocytes protect neurons from hydrogen peroxide toxicity
-
Desagher S, Glowinski J, Premont J. 1996. Astrocytes protect neurons from hydrogen peroxide toxicity. J Neurosci 16:2553-2562.
-
(1996)
J Neurosci
, vol.16
, pp. 2553-2562
-
-
Desagher, S.1
Glowinski, J.2
Premont, J.3
-
13
-
-
70350545722
-
Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR Complex 2 by S6K1
-
Dibble CC, Asara JM, Manning BD. 2009. Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR Complex 2 by S6K1. Mol Cell Biol 29:5657-5670.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5657-5670
-
-
Dibble, C.C.1
Asara, J.M.2
Manning, B.D.3
-
14
-
-
0033899176
-
Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species
-
Dringen R, Gutterer JM, Hirrlinger J. 2000. Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur J Biochem 267:4912-4916.
-
(2000)
Eur J Biochem
, vol.267
, pp. 4912-4916
-
-
Dringen, R.1
Gutterer, J.M.2
Hirrlinger, J.3
-
16
-
-
1542317072
-
Reactive astrocytes protect tissue and preserve function after spinal cord injury
-
Faulkner JR, Herrmann JE, Woo MJ, Tansey KE, Doan NB, Sofroniew MV. 2004. Reactive astrocytes protect tissue and preserve function after spinal cord injury. J Neurosci 24:2143-2155.
-
(2004)
J Neurosci
, vol.24
, pp. 2143-2155
-
-
Faulkner, J.R.1
Herrmann, J.E.2
Woo, M.J.3
Tansey, K.E.4
Doan, N.B.5
Sofroniew, M.V.6
-
17
-
-
0030657941
-
Neuronal soluble factors differentially regulate the expression of the GLT-1 and GLAST glutamate transporters in cultured astroglia
-
Gegelashvili G, Danbolt NC, Schousboe A. 1997. Neuronal soluble factors differentially regulate the expression of the GLT-1 and GLAST glutamate transporters in cultured astroglia. J Neurochem 69:2612-2615.
-
(1997)
J Neurochem
, vol.69
, pp. 2612-2615
-
-
Gegelashvili, G.1
Danbolt, N.C.2
Schousboe, A.3
-
18
-
-
79959640003
-
Nuclear factor-k{cyrillic}B contributes to neuron-dependent induction of glutamate transporter-1 expression in astrocytes
-
Ghosh M, Yang Y, Rothstein JD, Robinson MB. 2011. Nuclear factor-k{cyrillic}B contributes to neuron-dependent induction of glutamate transporter-1 expression in astrocytes. J Neurosci 31:9159-9169.
-
(2011)
J Neurosci
, vol.31
, pp. 9159-9169
-
-
Ghosh, M.1
Yang, Y.2
Rothstein, J.D.3
Robinson, M.B.4
-
19
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin DA, Sabatini DM. 2007. Defining the role of mTOR in cancer. Cancer Cell 12:9-22.
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
20
-
-
33751348056
-
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
-
Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. 2006. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev Cell 11:859-871.
-
(2006)
Dev Cell
, vol.11
, pp. 859-871
-
-
Guertin, D.A.1
Stevens, D.M.2
Thoreen, C.C.3
Burds, A.A.4
Kalaany, N.Y.5
Moffat, J.6
Brown, M.7
Fitzgerald, K.J.8
Sabatini, D.M.9
-
21
-
-
42949139481
-
AMPK phosphorylation of Raptor mediates a metabolic checkpoint
-
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, Turk BE, Shaw RJ. 2008. AMPK phosphorylation of Raptor mediates a metabolic checkpoint. Mol Cell 30:214-226.
-
(2008)
Mol Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
Mihaylova, M.M.4
Mery, A.5
Vasquez, D.S.6
Turk, B.E.7
Shaw, R.J.8
-
22
-
-
33846621575
-
The tripartite synapse: Roles for gliotransmission in health and disease
-
Halassa MM, Fellin T, Haydon PG. 2007. The tripartite synapse: Roles for gliotransmission in health and disease. Trends Mol Med 13:54-63.
-
(2007)
Trends Mol Med
, vol.13
, pp. 54-63
-
-
Halassa, M.M.1
Fellin, T.2
Haydon, P.G.3
-
23
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR) mediates TOR action
-
Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K. 2002. Raptor, a binding partner of target of rapamycin (TOR) mediates TOR action. Cell 110:177-189.
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
24
-
-
33644943620
-
AMPK: A key sensor of fuel and energy status in skeletal muscle
-
Hardie DG, Sakamoto K. 2006. AMPK: A key sensor of fuel and energy status in skeletal muscle. Physiol (Bethesda) 21:48-60.
-
(2006)
Physiol (Bethesda)
, vol.21
, pp. 48-60
-
-
Hardie, D.G.1
Sakamoto, K.2
-
25
-
-
2942575981
-
Glutamate transporters bring competition to the synapse
-
Huang YH, Bergles DE. 2004. Glutamate transporters bring competition to the synapse. Curr Opin Neurobiol 14:346-352.
-
(2004)
Curr Opin Neurobiol
, vol.14
, pp. 346-352
-
-
Huang, Y.H.1
Bergles, D.E.2
-
26
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127:125-137.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
Huang, Q.7
Qin, J.8
Su, B.9
-
27
-
-
79951950577
-
Insulin increases glutamate transporter GLT-1 in cultured astrocytes
-
Ji YF, Xu SM, Zhu J, Wang XX, Shen Y. 2011. Insulin increases glutamate transporter GLT-1 in cultured astrocytes. Biochem Biophys Res Commun 405:691-696.
-
(2011)
Biochem Biophys Res Commun
, vol.405
, pp. 691-696
-
-
Ji, Y.F.1
Xu, S.M.2
Zhu, J.3
Wang, X.X.4
Shen, Y.5
-
28
-
-
75749105049
-
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling
-
Julien LA, Carriere A, Moreau J, Roux PP. 2010. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. Mol Cell Biol 30:908-921.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 908-921
-
-
Julien, L.A.1
Carriere, A.2
Moreau, J.3
Roux, P.P.4
-
29
-
-
0030858918
-
Family of neutral and acidic amino acid transporters: Molecular biology, physiology and medical implications
-
Kanai Y. 1997. Family of neutral and acidic amino acid transporters: Molecular biology, physiology and medical implications. Curr Opin Cell Biol 9:565-572.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 565-572
-
-
Kanai, Y.1
-
30
-
-
0036917896
-
Selective blockade of astrocytic glutamate transporter GLT-1 with dihydrokainate prevents neuronal death during ouabain treatment of astrocyte/neuron cocultures
-
Kawahara K, Hosoya R, Sato H, Tanaka M, Nakajima T, Iwabuchi S. 2002. Selective blockade of astrocytic glutamate transporter GLT-1 with dihydrokainate prevents neuronal death during ouabain treatment of astrocyte/neuron cocultures. Glia 40:337-349.
-
(2002)
Glia
, vol.40
, pp. 337-349
-
-
Kawahara, K.1
Hosoya, R.2
Sato, H.3
Tanaka, M.4
Nakajima, T.5
Iwabuchi, S.6
-
31
-
-
13544254640
-
Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures
-
Kawahara K, Kosugi T, Tanaka M, Nakajima T, Yamada T. 2005. Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures. Glia 49:349-359.
-
(2005)
Glia
, vol.49
, pp. 349-359
-
-
Kawahara, K.1
Kosugi, T.2
Tanaka, M.3
Nakajima, T.4
Yamada, T.5
-
32
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL. 2011. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 13:132-141.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
33
-
-
0028950574
-
Expression of glutamate transporters in cultured glial cells
-
Kondo K, Hashimoto H, Kitanaka J, Sawada M, Suzumura A, Marunouchi T, Baba A. 1995. Expression of glutamate transporters in cultured glial cells. Neurosci Lett 188:140-142.
-
(1995)
Neurosci Lett
, vol.188
, pp. 140-142
-
-
Kondo, K.1
Hashimoto, H.2
Kitanaka, J.3
Sawada, M.4
Suzumura, A.5
Marunouchi, T.6
Baba, A.7
-
34
-
-
70350418625
-
mTOR signaling at a glance
-
Laplante M, Sabatini DM. 2009. mTOR signaling at a glance. J Cell Sci 122:3589-3594.
-
(2009)
J Cell Sci
, vol.122
, pp. 3589-3594
-
-
Laplante, M.1
Sabatini, D.M.2
-
35
-
-
84860653702
-
Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes
-
Lee E, Sidoryk-Wegrzynowicz M, Yin Z, Webb A, Son DS, Aschner M. 2012. Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes. Glia 60:1024-1036.
-
(2012)
Glia
, vol.60
, pp. 1024-1036
-
-
Lee, E.1
Sidoryk-Wegrzynowicz, M.2
Yin, Z.3
Webb, A.4
Son, D.S.5
Aschner, M.6
-
36
-
-
33645847822
-
Regulation of astrocytic glutamate transporter expression by Akt: Evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype
-
Li LB, Toan SV, Zelenaia O, Watson DJ, Wolfe JH, Rothstein JD, Robinson MB. 2006. Regulation of astrocytic glutamate transporter expression by Akt: Evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype. J Neurochem 97:759-771.
-
(2006)
J Neurochem
, vol.97
, pp. 759-771
-
-
Li, L.B.1
Toan, S.V.2
Zelenaia, O.3
Watson, D.J.4
Wolfe, J.H.5
Rothstein, J.D.6
Robinson, M.B.7
-
37
-
-
0030872412
-
Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression
-
Li S, Mallory M, Alford M, Tanaka S, Masliah E. 1997. Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression. J Neuropathol Exp Neurol 56:901-911.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 901-911
-
-
Li, S.1
Mallory, M.2
Alford, M.3
Tanaka, S.4
Masliah, E.5
-
39
-
-
0030767736
-
Hypoxia-ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn pig striatum
-
Martin LJ, Brambrink AM, Lehmann C, Portera-Cailliau C, Koehler R, Rothstein J, Traystman RJ. 1997. Hypoxia-ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn pig striatum. Ann Neurol 42:335-348.
-
(1997)
Ann Neurol
, vol.42
, pp. 335-348
-
-
Martin, L.J.1
Brambrink, A.M.2
Lehmann, C.3
Portera-Cailliau, C.4
Koehler, R.5
Rothstein, J.6
Traystman, R.J.7
-
40
-
-
84864013769
-
Cell surface turnover of the glutamate transporter GLT-1 is mediated by ubiquitination/deubiquitination
-
Martínez-Villarreal J, García Tardón N, Ibáñez I, Giménez C, Zafra F. 2012. Cell surface turnover of the glutamate transporter GLT-1 is mediated by ubiquitination/deubiquitination. Glia 60:1356-1365.
-
(2012)
Glia
, vol.60
, pp. 1356-1365
-
-
Martínez-Villarreal, J.1
García Tardón, N.2
Ibáñez, I.3
Giménez, C.4
Zafra, F.5
-
41
-
-
0033015919
-
Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy
-
Mathern GW, Mendoza D, Lozada A, Pretorius JK, Dehnes Y, Danbolt NC, Nelson N, Leite JP, Chimelli L, Born DE, Sakamoto AC, Assirati JA, Fried I, Peacock WJ, Ojemann GA, Adelson PD. 1999. Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. Neurol 52:453-472.
-
(1999)
Neurol
, vol.52
, pp. 453-472
-
-
Mathern, G.W.1
Mendoza, D.2
Lozada, A.3
Pretorius, J.K.4
Dehnes, Y.5
Danbolt, N.C.6
Nelson, N.7
Leite, J.P.8
Chimelli, L.9
Born, D.E.10
Sakamoto, A.C.11
Assirati, J.A.12
Fried, I.13
Peacock, W.J.14
Ojemann, G.A.15
Adelson, P.D.16
-
43
-
-
54849417590
-
Mechanisms of substrate transport-induced clustering of a glial glutamate transporter GLT-1 in astroglial-neuronal cultures
-
Nakagawa T, Otsubo Y, Yatani Y, Shirakawa H, Kaneko S. 2008. Mechanisms of substrate transport-induced clustering of a glial glutamate transporter GLT-1 in astroglial-neuronal cultures. Eur J Neurosci 28:1719-1730.
-
(2008)
Eur J Neurosci
, vol.28
, pp. 1719-1730
-
-
Nakagawa, T.1
Otsubo, Y.2
Yatani, Y.3
Shirakawa, H.4
Kaneko, S.5
-
44
-
-
0346094456
-
+ entry through TRPM7 channels and anoxic neuronal death
-
+ entry through TRPM7 channels and anoxic neuronal death. Cell 115:768-770.
-
(2003)
Cell
, vol.115
, pp. 768-770
-
-
Nicotera, P.1
Bano, D.2
-
45
-
-
32944457518
-
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
O'Reilly KE, Rojo F, She QB, Solit D, Mills GB, Smith D, Lane H, Hofmann F, Hicklin DJ, Ludwig DL, Baselga J, Rosen N. 2006. mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res 66:1500-1508.
-
(2006)
Cancer Res
, vol.66
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
Lane, H.7
Hofmann, F.8
Hicklin, D.J.9
Ludwig, D.L.10
Baselga, J.11
Rosen, N.12
-
46
-
-
0033517189
-
NF-k{cyrillic}B activation by tumor necrosis factor requires the Akt serine and threonine kinase
-
Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. 1999. NF-k{cyrillic}B activation by tumor necrosis factor requires the Akt serine and threonine kinase. Nature 401:82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
47
-
-
69249146951
-
mTOR/S6 Kinase pathway contributes to astrocyte survival during ischemia
-
Pastor MD, García-Yébenes I, Fradejas N, Pérez-Ortiz JM, Mora-Lee S, Tranque P, Moro MA, Pende M, Calvo S. 2009. mTOR/S6 Kinase pathway contributes to astrocyte survival during ischemia. J Biol Chem 284:22067-22078.
-
(2009)
J Biol Chem
, vol.284
, pp. 22067-22078
-
-
Pastor, M.D.1
García-Yébenes, I.2
Fradejas, N.3
Pérez-Ortiz, J.M.4
Mora-Lee, S.5
Tranque, P.6
Moro, M.A.7
Pende, M.8
Calvo, S.9
-
48
-
-
2642709999
-
Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain
-
Rao VLR, Baskaya MK, Dogan A, Rothstein JD, Dempsey RJ. 1998. Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain. J Neurochem 70:2020-2027.
-
(1998)
J Neurochem
, vol.70
, pp. 2020-2027
-
-
Rao, V.L.R.1
Baskaya, M.K.2
Dogan, A.3
Rothstein, J.D.4
Dempsey, R.J.5
-
49
-
-
0034879989
-
Transient focal cerebral ischemia down-regulates glutamate transporters GLT-1 and EAAC1 expression in rat brain neurochemical research
-
Rao VLR, Bowen KK, Dempsey RJ. 2001a. Transient focal cerebral ischemia down-regulates glutamate transporters GLT-1 and EAAC1 expression in rat brain neurochemical research. Neurochem Res 26:497-502.
-
(2001)
Neurochem Res
, vol.26
, pp. 497-502
-
-
Rao, V.L.R.1
Bowen, K.K.2
Dempsey, R.J.3
-
50
-
-
0035869460
-
Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbated transient focal cerebral ischemia-induced neuronal damage in rat brain
-
Rao VLR, Dogan A, Todd KG, Bowen KK, Kim B-T, Rothstein JD, Dempsey RJ. 2001b. Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbated transient focal cerebral ischemia-induced neuronal damage in rat brain. J Neurosci 21:1876-1883.
-
(2001)
J Neurosci
, vol.21
, pp. 1876-1883
-
-
Rao, V.L.R.1
Dogan, A.2
Todd, K.G.3
Bowen, K.K.4
Kim, B.-T.5
Rothstein, J.D.6
Dempsey, R.J.7
-
51
-
-
34250870091
-
Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS
-
Regan MR, Huang YH, Kim YS, Dykes-Hoberg MI, Jin L, Watkins M, Bergles DE, Rothstein JD. 2007. Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS. J Neurosci 27:6607-6619.
-
(2007)
J Neurosci
, vol.27
, pp. 6607-6619
-
-
Regan, M.R.1
Huang, Y.H.2
Kim, Y.S.3
Dykes-Hoberg, M.I.4
Jin, L.5
Watkins, M.6
Bergles, D.E.7
Rothstein, J.D.8
-
52
-
-
0032449129
-
The family of sodium-dependent glutamate transporters: A focus on the GLT-1/EAAT2 subtype
-
Robinson MB. 1998. The family of sodium-dependent glutamate transporters: A focus on the GLT-1/EAAT2 subtype. Neurochem Int 33:479-491.
-
(1998)
Neurochem Int
, vol.33
, pp. 479-491
-
-
Robinson, M.B.1
-
53
-
-
1242314199
-
In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway
-
Romera C, Hurtado O, Botella SH, Lizasoain I, Cárdenas A, Fernández-Tomé P, Leza JC, Lorenzo P, Moro MA. 2004. In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway. J Neurosci 24:1350-1357.
-
(2004)
J Neurosci
, vol.24
, pp. 1350-1357
-
-
Romera, C.1
Hurtado, O.2
Botella, S.H.3
Lizasoain, I.4
Cárdenas, A.5
Fernández-Tomé, P.6
Leza, J.C.7
Lorenzo, P.8
Moro, M.A.9
-
54
-
-
34250741677
-
Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection
-
Romera C, Hurtado O, Mallolas J, Pereira MP, Morales JR, Romera A, Serena J, Vivancos J, Nombela F, Lorenzo P, Lizasoain I, Moro MA. 2007. Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection. J Cereb Blood Flow Metab 27:1327-1338.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1327-1338
-
-
Romera, C.1
Hurtado, O.2
Mallolas, J.3
Pereira, M.P.4
Morales, J.R.5
Romera, A.6
Serena, J.7
Vivancos, J.8
Nombela, F.9
Lorenzo, P.10
Lizasoain, I.11
Moro, M.A.12
-
55
-
-
52949137425
-
Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: Rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1
-
Rosner M, Hengstschläger M. 2008. Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: Rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1. Hum Mol Genet 17:2934-2948.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2934-2948
-
-
Rosner, M.1
Hengstschläger, M.2
-
56
-
-
0028060648
-
Localization of neuronal and glial glutamate transporters
-
Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW. 1994. Localization of neuronal and glial glutamate transporters. Neuron 13:713-725.
-
(1994)
Neuron
, vol.13
, pp. 713-725
-
-
Rothstein, J.D.1
Martin, L.2
Levey, A.I.3
Dykes-Hoberg, M.4
Jin, L.5
Wu, D.6
Nash, N.7
Kuncl, R.W.8
-
57
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW. 1995. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38:73-84.
-
(1995)
Ann Neurol
, vol.38
, pp. 73-84
-
-
Rothstein, J.D.1
Van Kammen, M.2
Levey, A.I.3
Martin, L.J.4
Kuncl, R.W.5
-
58
-
-
33747819801
-
mTOR and cancer: Insights into a complex relationship
-
Sabatini DM. 2006. mTOR and cancer: Insights into a complex relationship. Nat Rev Cancer 6:729-734.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 729-734
-
-
Sabatini, D.M.1
-
59
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF, Markhard AL, Sabatini DM. 2006. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 22:159-168.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
60
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
62
-
-
0032925862
-
Excitatory amino acid transporters: A family in flux
-
Seal RP, Amara SG. 1999. Excitatory amino acid transporters: A family in flux. Ann Rev Pharmacol Toxicol 39:431-456.
-
(1999)
Ann Rev Pharmacol Toxicol
, vol.39
, pp. 431-456
-
-
Seal, R.P.1
Amara, S.G.2
-
63
-
-
84883613359
-
Distinct functions of nuclear distribution proteins LIS1, Ndel1 and NudCL in regulating axonal mitochondrial transport
-
Shao CY, Zhu J, Xie YJ, Wang Z, Wang YN, Wang Y, Su LD, Zhou L, Zhou TH, Shen Y. 2013. Distinct functions of nuclear distribution proteins LIS1, Ndel1 and NudCL in regulating axonal mitochondrial transport. Traffic 14:785-797.
-
(2013)
Traffic
, vol.14
, pp. 785-797
-
-
Shao, C.Y.1
Zhu, J.2
Xie, Y.J.3
Wang, Z.4
Wang, Y.N.5
Wang, Y.6
Su, L.D.7
Zhou, L.8
Zhou, T.H.9
Shen, Y.10
-
64
-
-
56349112723
-
Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1
-
Sheldon A, González M, Krizman-Genda E, Susarla B, Robinson MB. 2008. Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1. Neurochem Int 53:296-308.
-
(2008)
Neurochem Int
, vol.53
, pp. 296-308
-
-
Sheldon, A.1
González, M.2
Krizman-Genda, E.3
Susarla, B.4
Robinson, M.B.5
-
65
-
-
0033452720
-
Characterization of AMPA receptors on isolated amacrine-like cells in carp retina
-
Shen Y, Zhou Y, Yang XL. 1999. Characterization of AMPA receptors on isolated amacrine-like cells in carp retina. Eur J Neurosci 11:4233-4240.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 4233-4240
-
-
Shen, Y.1
Zhou, Y.2
Yang, X.L.3
-
66
-
-
29144460321
-
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
-
Shin JY, Fang ZH, Yu ZX, Wang CE, Li SH, Li XJ. 2005. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J Cell Biol 171:1001-1012.
-
(2005)
J Cell Biol
, vol.171
, pp. 1001-1012
-
-
Shin, J.Y.1
Fang, Z.H.2
Yu, Z.X.3
Wang, C.E.4
Li, S.H.5
Li, X.J.6
-
67
-
-
23844438209
-
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition
-
Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, Khuri FR. 2005. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. Cancer Res 65:7052-7058.
-
(2005)
Cancer Res
, vol.65
, pp. 7052-7058
-
-
Sun, S.Y.1
Rosenberg, L.M.2
Wang, X.3
Zhou, Z.4
Yue, P.5
Fu, H.6
Khuri, F.R.7
-
68
-
-
38649137724
-
Internalization and degradation of the glutamate transporter GLT-1 in response to phorbol ester
-
Susarla B, Robinson MB. 2008. Internalization and degradation of the glutamate transporter GLT-1 in response to phorbol ester. Neurochem Int 52:709-722.
-
(2008)
Neurochem Int
, vol.52
, pp. 709-722
-
-
Susarla, B.1
Robinson, M.B.2
-
69
-
-
0031020015
-
Neuronal regulation of glutamate transporter subtype expression in astrocytes
-
Swanson RA, Liu J, Miller JW, Rothstein JD, Farrell K, Stein BA, Longuemare MC. 1997. Neuronal regulation of glutamate transporter subtype expression in astrocytes. J Neurosci 17:932-940.
-
(1997)
J Neurosci
, vol.17
, pp. 932-940
-
-
Swanson, R.A.1
Liu, J.2
Miller, J.W.3
Rothstein, J.D.4
Farrell, K.5
Stein, B.A.6
Longuemare, M.C.7
-
70
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
Tanaka K, Watase K, Manabe T, Yamada K, Watanabe M, Takahashi K, Iwama H, Nishikawa T, Ichihara N, Kikuchi T, Okuyama S, Kawashima N, Hori S, Takimoto M, Wada K. 1997. Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science 276:1699-1702.
-
(1997)
Science
, vol.276
, pp. 1699-1702
-
-
Tanaka, K.1
Watase, K.2
Manabe, T.3
Yamada, K.4
Watanabe, M.5
Takahashi, K.6
Iwama, H.7
Nishikawa, T.8
Ichihara, N.9
Kikuchi, T.10
Okuyama, S.11
Kawashima, N.12
Hori, S.13
Takimoto, M.14
Wada, K.15
-
71
-
-
0028904229
-
Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus
-
Torp R, Lekieffre D, Levy LM, Haug FM, Danbolt NC, Meldrum BS, Ottersen OP. 1995. Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus. Exp Brain Res 103:51-58.
-
(1995)
Exp Brain Res
, vol.103
, pp. 51-58
-
-
Torp, R.1
Lekieffre, D.2
Levy, L.M.3
Haug, F.M.4
Danbolt, N.C.5
Meldrum, B.S.6
Ottersen, O.P.7
-
72
-
-
77149163803
-
Rictor is a novel target of p70 S6 kinase-1
-
Treins C, Warne PH, Magnuson MA, Pende M, Downward J. 2010. Rictor is a novel target of p70 S6 kinase-1. Oncogene 29:1003-1016.
-
(2010)
Oncogene
, vol.29
, pp. 1003-1016
-
-
Treins, C.1
Warne, P.H.2
Magnuson, M.A.3
Pende, M.4
Downward, J.5
-
73
-
-
14244252683
-
Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes
-
Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A. 2005. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes. Endocrinology 146:1328-1337.
-
(2005)
Endocrinology
, vol.146
, pp. 1328-1337
-
-
Tremblay, F.1
Gagnon, A.2
Veilleux, A.3
Sorisky, A.4
Marette, A.5
-
74
-
-
66049119030
-
Activation of the mammalian target of rapamycin. (mTOR) is essential for oligodendrocyte differentiation
-
Tyler WA, Gangoli N, Gokina P, Kim HA, Covey M, Levison SW, Wood TL. 2009. Activation of the mammalian target of rapamycin. (mTOR) is essential for oligodendrocyte differentiation. J Neurosci 29:6367-6378.
-
(2009)
J Neurosci
, vol.29
, pp. 6367-6378
-
-
Tyler, W.A.1
Gangoli, N.2
Gokina, P.3
Kim, H.A.4
Covey, M.5
Levison, S.W.6
Wood, T.L.7
-
75
-
-
64849116285
-
Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002
-
Werzowa J, Cejka D, Fuereder T, Dekrout B, Thallinger C, Pehamberger H, Wacheck V, Pratscher B. 2009. Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002. Br J Dermatol 160:955-964.
-
(2009)
Br J Dermatol
, vol.160
, pp. 955-964
-
-
Werzowa, J.1
Cejka, D.2
Fuereder, T.3
Dekrout, B.4
Thallinger, C.5
Pehamberger, H.6
Wacheck, V.7
Pratscher, B.8
-
76
-
-
77949272199
-
PI3K/Akt/mTOR signaling regulates glutamate transporter 1 in astrocytes
-
Wu X, Kihara T, Akaike A, Niidome T, Sugimoto H. 2010. PI3K/Akt/mTOR signaling regulates glutamate transporter 1 in astrocytes. Biochem Biophys Res Commun 393:514-518.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 514-518
-
-
Wu, X.1
Kihara, T.2
Akaike, A.3
Niidome, T.4
Sugimoto, H.5
-
77
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN. 2006. TOR signaling in growth and metabolism. Cell 124:471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
79
-
-
62549128641
-
Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT-1
-
Yang YJ, Gozen O, Watkins A, Lorenzini I, Lepore A, Gao YZ, Vidensky S, Brennan J, Poulsen D, Park JW, Jeon NL, Robinson MB, Rothstein JD. 2009. Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT-1. Neuron 61:880-894.
-
(2009)
Neuron
, vol.61
, pp. 880-894
-
-
Yang, Y.J.1
Gozen, O.2
Watkins, A.3
Lorenzini, I.4
Lepore, A.5
Gao, Y.Z.6
Vidensky, S.7
Brennan, J.8
Poulsen, D.9
Park, J.W.10
Jeon, N.L.11
Robinson, M.B.12
Rothstein, J.D.13
-
80
-
-
0034038270
-
Epidermal growth factor receptor agonists increase expression of glutamate transporter GLT-1 in astrocytes through pathways dependent on phosphatidylinositol 3-kinase and transcription factor NF-kappaB
-
Zelenaia O, Schlag BD, Gochenauer GE, Ganel R, Song W, Beesley JS, Grinspan JB, Rothstein JD, Robinson MB. 2000. Epidermal growth factor receptor agonists increase expression of glutamate transporter GLT-1 in astrocytes through pathways dependent on phosphatidylinositol 3-kinase and transcription factor NF-kappaB. Mol Pharmacol 57:667-678.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 667-678
-
-
Zelenaia, O.1
Schlag, B.D.2
Gochenauer, G.E.3
Ganel, R.4
Song, W.5
Beesley, J.S.6
Grinspan, J.B.7
Rothstein, J.D.8
Robinson, M.B.9
-
81
-
-
42949140259
-
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
-
Zeng LH, Xu L, Gutmann DH, Wong M. 2008. Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol 63:444-453.
-
(2008)
Ann Neurol
, vol.63
, pp. 444-453
-
-
Zeng, L.H.1
Xu, L.2
Gutmann, D.H.3
Wong, M.4
-
82
-
-
3242693273
-
Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity
-
Zhou J, Sutherland ML. 2004. Glutamate transporter cluster formation in astrocytic processes regulates glutamate uptake activity. J Neurosci 24:6301-6306.
-
(2004)
J Neurosci
, vol.24
, pp. 6301-6306
-
-
Zhou, J.1
Sutherland, M.L.2
-
83
-
-
84866715394
-
Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons
-
Zhu J, Shao CY, Yang W, Zhang XM, Wu ZY, Zhou L, Wang XX, Li YH, Xia J, Luo JH, Shen Y. 2012. Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons. PLoS One 7:e46012.
-
(2012)
PLoS One
, vol.7
-
-
Zhu, J.1
Shao, C.Y.2
Yang, W.3
Zhang, X.M.4
Wu, Z.Y.5
Zhou, L.6
Wang, X.X.7
Li, Y.H.8
Xia, J.9
Luo, J.H.10
Shen, Y.11
|