Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes

Acta Pharmacologica Sinica

Volumn 33, Issue 3, 2012, Pages 385-392

  Chen, Lei Lei ^a   Wu, Jun Chao ^a   Wang, Lin Hui ^a   Wang, Jin ^a   Qin, Zheng Hong ^a   Difiglia, Marian ^b   Lin, Fang ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

3 MA; autophagy; GLT 1; glutamate uptake; huntingtin 552; Huntington's disease; rapamycin

Indexed keywords

3 METHYLADENINE; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; HUNTINGTIN; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN GLT 1; PROTEIN P62; RAPAMYCIN; UNCLASSIFIED DRUG;

ADENOVIRUS INFECTION; AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; HUNTINGTON CHOREA; LIQUID SCINTILLATION COUNTING; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; EXCITATORY AMINO ACID TRANSPORTER 2; HUNTINGTON DISEASE; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIROLIMUS;

EID: 84863278527     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.162     Document Type: Article

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