Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain

Journal of Neuroscience

Volumn 21, Issue 6, 2001, Pages 1876-1883

  Rao, Vemuganti L Raghavendra ^a,b   Dogan, Aclan ^a   Todd, Kathryn G ^d   Bowen, Kellie K ^a   Kim, Bum Tae ^a,e   Rothstein, Jeffrey D ^f   Dempsey, Robert J ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b University of Wisconsin Cardiovascular Research Center   (United States)

^c WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^d UNIVERSITY OF ALBERTA   (Canada)

^e Soonchunhyang University College of Medicine   (South Korea)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antisense knockdown; EAAC1; Focal cerebral ischemia; GLT 1; Glutamate transporters; Middle cerebral artery occlusion; Neuronal damage; Stroke

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GLUTAMATE TRANSPORTER;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; KNOCKOUT GENE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; NERVE CELL LESION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035869460     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-06-01876.2001     Document Type: Article

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