Micro- and Nanopatterning of Active Biomolecules and Cells

Intelligent Surfaces in Biotechnology: Scientific and Engineering Concepts, Enabling Technologies, and Translation to Bio-Oriented Applications

Volumn , Issue , 2012, Pages 291-319

  Aydin, Daniel ^a,b   Hirschfeld Warneken, Vera C ^a,b   Louban, Ilia ^a,b   Spatz, Joachim P ^a,b  

^a MAX PLANCK INSTITUTE FOR INTELLIGENT SYSTEMS   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

BCML; Biosensor nanopatterning; Immobilization chemistry; Micellar nanolithography; Nanoscale control, and cell response

Indexed keywords

EID: 84886520929     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118181249.ch8     Document Type: Chapter

References (105)

1. Torres , A.J. , Wu , M. , Holowka , D. , & Baird , B. Nanobiotechnology and cell biology: micro- and nanofabricated surfaces to investigate receptor - mediated signaling . Annual Reviews of Biophysics 37 , 265 - 288 ( 2008 ).
2. Jonkheijm , P. , Weinrich , D. , Schroder , H. , Niemeyer , C.M. , & Waldmann , H. Chemical strategies for generating protein biochips . Angewandte Chemie (International ed. in English) 47 , 9618 - 9647 ( 2008 ).
3. Holland - Nell , K. & Beck - Sickinger , A.G. Specifically immobilised aldo/keto reductase AKR1A1 shows a dramatic increase in activity relative to the randomly immobilised enzyme . Chembiochem 8 , 1071 - 1076 ( 2007 ).
4. Hearn , M.T. & Acosta , D. Applications of novel affinity cassette methods: use of peptide fusion handles for the purification of recombinant proteins . Journal of Molecular Recognition 14 , 323 - 369 ( 2001 ).
5. Miller , D.M. , 3rd. , Olson , J.S. , Pflugrath , J.W. , & Quiocho , F.A. Rates of ligand binding to periplasmic proteins involved in bacterial transport and chemotaxis . The Journal of Biological Chemistry 258 , 13665 - 13672 ( 1983 ).
6. Terpe , K. Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems . Applied Microbiology and Biotechnology 60 , 523 - 533 ( 2003 ).
7. Waugh, D.S. Making the most of affinity tags . Trends in Biotechnology 23 , 316 - 320 ( 2005 ).
8. Lesaicherre , M.L. , Lue , R.Y. , Chen , G.Y. , Zhu , Q. , & Yao , S.Q. Intein - mediated biotinylation of proteins and its application in a protein microarray . Journal of the American Chemical Society 124 , 8768 - 8769 ( 2002 ).
9. Duckworth , B.P. , Xu , J. , Taton , T.A. , Guo , A. , & Distefano , M.D. Site - specific, covalent attachment of proteins to a solid surface . Bioconjugate Chemistry 17 , 967 - 974 ( 2006 ).
10. Soellner , M.B. , Dickson , K.A. , Nilsson , B.L. , & Raines , R.T. Site - specific protein immobilization by Staudinger ligation . Journal of the American Chemical Society 125 , 11790 - 11791 ( 2003 ).
11. Lata , S. , Gavutis , M. , Tampe , R. , & Piehler , J. Specific and stable fluorescence labeling of histidine - tagged proteins for dissecting multi - protein complex formation . Journal of the American Chemical Society 128 , 2365 - 2372 ( 2006 ).
12. Lata , S. & Piehler , J. Stable and functional immobilization of histidine - tagged proteins via multivalent chelator headgroups on a molecular poly(ethylene glycol) brush . Analytical Chemistry 77 , 1096 - 1105 ( 2005 ).
13. Johnson , D. & Martin , L. Controlling protein orientation at interfaces using histidine tags: an alternative to Ni/NTA . Journal of the American Chemical Society 127 , 2018 - 2019 ( 2005 ).
14. Marin , V.L. , Bayburt , T.H. , Sligar , S.G. , & Mrksich , M. Functional assays of membrane - bound proteins with SAMDI - TOF mass spectrometry . Angewandte Chemie (International ed. in English) 46 , 8796 - 8798 ( 2007 ).
15. Zompa , L. Metal complexes of cyclic triamines. 2. Stability and electronic spectra of nickel (II), copper (II), and zinc (II) complexes containing nine - through twelve - membered cyclic triamine ligands . Inorganic Chemistry 17 , 2531 - 2536 ( 1978 ).
16. Kumar , A. & Whitesides , G.M. Features of gold having micrometer to centimeter dimensions can be formed through a combination of stamping with an elastomeric stamp and an alkanethiol " ink " followed by chemical etching . Applied Physics Letters 63 , 2002 - 2004 ( 1993 ).
17. Whitesides , G.M. , Ostuni , E. , Takayama , S. , Jiang , X. , & Ingber , D.E. Soft lithography in biology and biochemistry . Annual Review of Biomedical Engineering 3 , 335 - 373 ( 2001 ).
18. Renault , J.P. et al. Fabricating arrays of single protein molecules on glass using microcontact printing . Journal of Physical Chemistry. B, Condensed Phase 107 , 703 - 711 ( 2003 ).
19. Coyer , S.R. , Garcia , A.J. , & Delamarche , E. Facile preparation of complex protein architectures with sub - 100 - nm resolution on surfaces . Angewandte Chemie (International ed. in English) 46 , 6837 - 6840 ( 2007 ).
20. Guo , L.J. Nanoimprint lithography: methods and material requirements . Advanced Materials 19 , 495 - 513 ( 2007 ).
21. Truskett , V.N. & Watts , M.P.C. Trends in imprint lithography for biological applications . Trends in Biotechnology 24 , 312 - 317 ( 2006 ).
22. Falconnet , D. , Koenig , A. , Assi , F. , & Textor , M. A combined photolithographic and molecular - assembly approach to produce functional micropatterns for applications in the biosciences . Advanced Functional Materials 14 , 749 - 756 ( 2004 ).
23. Falconnet , D. et al. A novel approach to produce protein nanopatterns by combining nanoimprint lithography and molecular self - assembly . Nano Letters 4 , 1909 - 1914 ( 2004 ).
24. Hoff , J.D. , Cheng , L.J. , Meyhofer , E. , Guo , L.J. , & Hunt , A.J. Nanoscale protein patterning by imprint lithography . Nano Letters 4 , 853 - 857 ( 2004 ).
25. Maury , P. et al. Creating nanopatterns of his - tagged proteins on surfaces by nanoimprint lithography using specific NiNTA - histidine interactions . Small 3 , 1584 - 1592 ( 2007 ).
26. Austin , M.D. et al. Fabrication of 5 nm line width and 14 nm pitch features by nanoimprint lithography . Applied Physics Letters 84 , 5299 - 5301 ( 2004 ).
27. Chou , S.Y. , Krauss , P.R. , Zhang , W. , Guo , L. , & Zhuang , L. Sub - 10 nm imprint lithography and applications . Journal of Vacuum Science & Technology. B 15 , 2897 - 2904 ( 1997 ).
28. Hua , F. et al. Polymer imprint lithography with molecular - scale resolution . Nano Letters 4 , 2467 - 2472 ( 2004 ).
29. Denis , F.A. , Pallandre , A. , Nysten , B. , Jonas , A.M. , & Dupont - Gillain , C.C. Alignment and assembly of adsorbed collagen molecules induced by anisotropic chemical nanopatterns . Small 1 , 984 - 991 ( 2005 ).
30. Turchanin , A. et al. Molecular self - assembly, chemical lithography, and biochemical tweezers: a path for the fabrication of functional nanometer - scale protein arrays . Advanced Materials 20 , 471 - 477 ( 2008 ).
31. Zhang , G.J. et al. Nanoscale patterning of protein using electron beam lithography of organosilane self - assembled monolayers . Small 1 , 833 - 837 ( 2005 ).
32. Christman , K.L. et al. Positioning multiple proteins at the nanoscale with electron beam cross - linked functional polymers . Journal of the American Chemical Society 131 , 30 - 31 ( 2009 ).
33. Piner , R.D. , Zhu , J. , Xu , F. , Hong , S. , & Mirkin , C.A. " Dip - pen " nanolithography . Science 283 , 661 - 663 ( 1999 ).
34. Salaita , K. , Wang , Y. , & Mirkin , C.A. Applications of dip - pen nanolithography . Nature Nanotechnology 2 , 145 - 155 ( 2007 ).
35. Noy , A. et al. Fabrication of luminescent nanostructures and polymer nanowires using dip - pen nanolithography . Nano Letters 2 , 109 - 112 ( 2002 ).
36. Gundiah , G. et al. Dip - pen nanolithography with magnetic Fe 2 O 3 nanocrystals . Applied Physics Letters 84 , 5341 - 5343 ( 2004 ).
37. Demers , L.M. et al. Direct patterning of modified oligonucleotides on metals and insulators by dip - pen nanolithography . Science 296 , 1836 - 1838 ( 2002 ).
38. Lee , K.B. , Lim , J.H. , & Mirkin , C.A. Protein nanostructures formed via direct - write dip - pen nanolithography . Journal of the American Chemical Society 125 , 5588 - 5589 ( 2003 ).
39. Lee , S.W. et al. Biologically active protein nanoarrays generated using parallel dip - pen nanolithography . Advanced Materials 18 , 1133 - 1136 ( 2006 ).
40. Lim , J.H. et al. Direct - write dip - pen nanolithography of proteins on modified silicon oxide surfaces . Angewandte Chemie (International ed. in English) 42 , 2309 - 2312 ( 2003 ).
41. Lee , K.B. , Park , S.J. , Mirkin , C.A. , Smith , J.C. , & Mrksich , M. Protein nanoarrays generated by dip - pen nanolithography . Science 295 , 1702 - 1705 ( 2002 ).
42. Salaita , K. et al. Sub - 100 nm, centimeter - scale, parallel dip - pen nanolithography . Small 1 , 940 - 945 ( 2005 ).
43. Salaita , K. et al. Massively parallel dip - pen nanolithography with 55.000 - pen two - dimensional arrays . Angewandte Chemie (International ed. in English) 45 , 7220 - 7223 ( 2006 ).
44. Huo , F. et al. Polymer pen lithography . Science 321 , 1658 - 1660 ( 2008 ).
45. Wang , Y. et al. A self - correcting inking strategy for cantilever arrays addressed by an inkjet printer and used for dip - pen nanolithography . Small 4 , 1666 - 1670 ( 2008 ).
46. Xu , S. & Liu , G. Nanometer - scale fabrication by simultaneous nanoshaving and molecular self - assembly . Langmuir 13 , 127 - 129 ( 1997 ).
47. Staii , C. , Wood , D.W. , & Scoles , G. Verification of biochemical activity for proteins nanografted on gold surfaces . Journal of the American Chemical Society 130 , 640 - 646 ( 2008 ).
48. Krishnamoorthy , S. , Hinderling , C. , & Heinzelmann , H. Nanoscale patterning with block copolymers . Materials Today 9 , 40 - 47 ( 2006 ).
49. Bates , F.S. & Fredrickson , G.H. Block copolymer thermodynamics: theory and experiment. Annual Review of Physical Chemistry 41 , 525 - 557 ( 1990 ).
50. Gao , Z. & Eisenberg , A. A model of micellization for block copolymers in solutions . Macromolecules 26 , 7353 - 7360 ( 1993 ).
51. Israelachvili , J.N. Intermolecular and Surface Forces , 2nd edn. London; Orlando, fl: Academic Press ( 1992 ).
52. Israelachvili , J.N. Self - assembly in two dimensions: surface micelles and domain formation in monolayers . Langmuir 10 , 3774 - 3781 ( 1994 ).
53. Izzo , D. & Marques , C.M. Formation of micelles of diblock and triblock copolymers in a selective solvent . Macromolecules 26 , 7189 - 7194 ( 1993 ).
54. Spatz , J.P. , Röscher , A. , Sheiko , S. , Krausch , G. , & Möller , M. Noble metal loaded block lonomers: micelle organization, adsorption of free chains and formation of thin films . Advanced Materials 7 , 731 - 735 ( 1995 ).
55. Glass , R. , Möller , M. , & Spatz , J.P. Block copolymer micelle nanolithography . Nanotechnology 14 , 1153 - 1160 ( 2003 ). doi:10.1088/0957 - 4484/14/10/314.
56. Arnold , M. et al. Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing . Nano Letters 8 , 2063 - 2069 ( 2008 ). doi:10.1021/nl801483w
57. Möller , M. et al. Ordering and packing periodicity of Au - containing block copolymer micelles . PMSE Preprints 90 , 255 - 256 ( 2004 ).
58. Darhuber , A.A. , Troian , S.M. , Miller , S.M. , & Wagner , S. Morphology of liquid microstructures on chemically patterned surfaces . Journal of Applied Physics 87 , 7768 - 7775 ( 2000 ).
59. Lohm ü ller , T. , Bock , E. , & Spatz , J.P. Synthesis of quasi - hexagonal ordered arrays of metallic nanoparticles with tuneable particle size . Advanced Materials 20 , 2297 - 2302 ( 2008 ).
60. Bl ü mmel , J. et al. Protein repellent properties of covalently attached PEG coatings on nanostructured SiO(2) - based interfaces . Biomaterials 28 , 4739 - 4747 ( 2007 ).
61. Aydin , D. et al. Polymeric substrates with tunable elasticity and nanoscopically controlled biomolecule presentation . Langmuir: The ACS Journal of Surfaces and Colloids , 26 ( 19 ), 15472 - 15480 ( 2010 ). doi:10.1021/la103065x
62. Gr ä ter , S.V. et al. Mimicking cellular environments by nanostructured soft interfaces . Nano Letters 7 , 1413 - 1418 ( 2007 ).
63. Arnold , M. et al. Activation of integrin function by nanopatterned adhesive interfaces . ChemPhysChem 5 , 383 - 388 ( 2004 ).
64. Aydin , D. et al. Micro - nanostructured protein arrays - a tool for geometrically controlled ligand presentation . Small 5 , 1014 - 1018 ( 2009 ).
65. Wolfram , T. , Belz , F. , Schön , T. , & Spatz , J.P. Site - specific presentation of single recombinant proteins in defined nanoarrays . Biointerphases 2 , 44 - 48 ( 2007 ).
66. Glass , R. et al. Micro - nanostructured interfaces fabricated by the use of inorganic block copolymer micellar monolayers as negative resist for electron - beam lithography . Advanced Functional Materials 13 , 569 - 575 ( 2003 ).
67. Glass , R. et al. Block copolymer micelle nanolithography on non - conductive substrates . New Journal of Physics 6 , 1 - 17 ( 2004 ).
68. Gorzolnik , B. , Mela , P. , & Möller , M. Nano - structured micropatterns by combination of block copolymer self - assembly and UV photolithography . Nanotechnology 17 , 5027 - 5032 ( 2006 ).
69. Mela , P. et al. Low - ion - dose FIB modification of monomicellar layers for the creation of highly ordered metal nanodot arrays . Small 3 , 1368 - 1373 ( 2007 ).
70. Yun , S.H. et al. Micropatterning of a single layer of nanoparticles by lithographical methods with diblock copolymer micelles . Nanotechnology 17 , 450 - 454 ( 2006 ).
71. Chen , J. , Mela , P. , Möller , M. , & Lensen , M. Microcontact deprinting: a technique to pattern gold nanoparticles . ACS Nano 3 , 1451 - 1456 ( 2009 ).
72. De Gennes , P.G. , Brochard - Wyart , F. , & Que ' re ' , D. Capillarity and Wetting Phenomena: Drops, Bubbles, Pearls, Waves . Springer Science + Business Media ( 2004 ).
73. Darhuber , A.A. , Troian , S.M. , Davis , J.M. , Miller , S.M. , & Wagner , S. Selective dip - coating of chemically micropatterned surfaces . Journal of Applied Physics 88 , 5119 - 5126 ( 2000 ).
74. Landau , L. & Levich , B. Dragging of a liquid by a moving plate . Acta Physicochimica USSR 17 , 42 - 54 ( 1942 ).
75. Wilson , S.D.R. The drag - out problem in film coating theory . Journal of Engineering Mathematics 16 , 209 - 221 ( 1982 ).
76. Engler , A.J. , Sen , S. , Sweeney , H.L. , & Discher , D.E. Matrix elasticity directs stem cell lineage specification . Cell 126 , 677 - 689 ( 2006 ).
77. Vogel , V. & Sheetz , M. Local force and geometry sensing regulate cell functions . Nature Reviews. Molecular Cell Biology 2006 , 265 - 275 ( 2004 ).
78. Gilmore , A.P. Anoikis . Cell Death and Differentiation 12 ( Suppl 2 ), 1473 - 1477 ( 2005 ).
79. Discher , D.E. , Janmey , P. , & Wang , Y.L. Tissue cells feel and respond to the stiffness of their substrate . Science 310 , 1139 - 1143 ( 2005 ).
80. Giancotti , F.G. & Ruoslahti , E. Integrin signaling. Science 285 , 1028 - 1032 ( 1999 ).
81. Ruoslahti, E. & Pierschbacher , M.D. New perspectives in cell adhesion: RGD and integrins . Science 238 , 491 - 497 ( 1987 ).
82. Bershadsky , A. , Kozlov , M. , & Geiger , B. Adhesion - mediated mechanosensitivity: a time to experiment, and a time to theorize . Current Opinion in Cell Biology 18 , 472 - 481 ( 2006 ).
83. Chen , C.S. Mechanotransduction - a field pulling together? Journal of Cell Science 121 , 3285 - 3292 ( 2008 ).
84. Biggs , M.J.P. , Richards , R.G. , Gadegaard , N. , Wilkinson , C.D.W. , & Dalby , M.J. The effects of nanoscale pits on primary human osteoblast adhesion formation and cellular spreading . Journal of Materials Science. Materials in Medicine 18 , 399 - 404 ( 2007 ).
85. Brunetti , V. et al. Neurons sense nanoscale roughness with nanometer sensitivity . Proceedings of the National Academy of Sciences of the United States of America 107 , 6264 - 6269 ( 2010 ).
86. Hirschfeld - Warneken , V.C. et al. Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches . European Journal of Cell Biology 87 , 743 - 750 ( 2008 ).
87. Meller , D. , Peters , K. , & Meller , K. Human cornea and sclera studied by atomic force microscopy . Cell and Tissue Research 288 , 111 - 118 ( 1997 ).
88. Ploetz , C. , Zycband , E.I. , & Birk , D.E. Collagen fibril assembly and deposition in the developing dermis: segmental deposition in extracellular compartments . Journal of Structural Biology 106 , 73 - 81 ( 1991 ).
89. Xiong , J. - P. et al. Crystal structure of the extracellular segment of integrin alphaV beta3 in complex with an Arg - Gly - Asp ligand . Science 296 , 151 - 155 ( 2002 ).
90. Xiong , J.P. et al. Crystal structure of the extracellular segment of integrin alphaV beta3 . Science 294 , 339 - 345 ( 2001 ).
91. Hynes , R.O. Integrins: bidirectional, allosteric signaling machines . Cell 110 , 673 - 687 ( 2002 ).
92. Maheshwari , G. , Brown , G. , Lauffenburger , D.A. , Wells , A. , & Griffith , L.G. Cell adhesion and motility depend on nanoscale RGD clustering . Journal of Cell Science 113 , 1677 - 1686 ( 2000 ).
93. Danilov , Y.N. & Juliano , R.L. (Arg - Gly - Asp)n - Albumin conjugates as a model substratum for integrin - mediated cell adhesion . Experimental Cell Research 182 , 186 - 196 ( 1989 ).
94. Selhuber - Unkel , C. et al. Cell adhesion strength is controlled by intermolecular spacing of adhesion receptors . Biophysical Journal 98 , 543 - 551 ( 2010 ).
95. Walter , N. , Selhuber , C. , Kessler , H. , & Spatz , J.P. Cellular unbinding forces of initial adhesion processes on nanopatterned surfaces probed with magnetic tweezers . Nano Letters 6 , 398 - 402 ( 2006 ).
96. Lauffenburger , D.A. & Horwitz , A.F. Cell migration: a physically integrated molecular process . Cell 84 , 359 - 369 ( 1996 ).
97. Döbereiner , H. , Dubin - Thaler , B. , Giannone , G. , & Sheetz , M. Force sensing and generation in cell phases: analyses of complex functions . Journal of Applied Physiology 98 , 1542 - 1546 ( 2005 ).
98. Arnold , M. et al. Cell interactions with hierarchically structured nano - patterned adhesive surfaces . Soft Matter 5 , 72 - 77 ( 2009 ). http://dx.doi.org/10.1039/B815634D.
99. Guignet , E.G. , Hovius , R. , & Vogel , H. Reversible site - selective labeling of membrane proteins in live cells . Nature Biotechnology 22 , 440 - 444 ( 2004 ).
100. Wegner , G.J. , Lee , H.J. , & Corn , R.M. Characterization and optimization of peptide arrays for the study of epitope - antibody interactions using surface plasmon resonance imaging . Analytical Chemistry 74 , 5161 - 5168 ( 2002 ).
101. Eliasson , M. et al. Chimeric IgG - binding receptors engineered from staphylococcal protein A and streptococcal protein G . The Journal of Biological Chemistry 263 , 4323 - 4327 ( 1988 ).
102. Tolbert , T. & Wong , C. Intein - mediated synthesis of proteins containing carbohydrates and other molecular probes . Journal of the American Chemical Society 122 , 5421 - 5428 ( 2000 ).
103. Duckworth , B.P. , Zhang , Z. , Hosokawa , A. , & Distefano , M.D. Selective labeling of proteins by using protein farnesyltransferase . Chembiochem 8 , 98 - 105 ( 2007 ).
104. Kho , Y. et al. A tagging - via - substrate technology for detection and proteomics of farnesylated proteins . Proceedings of the National Academy of Sciences of the United States of America 101 , 12479 - 12484 ( 2004 ).
105. Aydin , D. , Hirschfeld - Warneken , V. C. , Louban , I. , & Spatz , J. P. Intelligent induction of active biosystem responses at interfaces . International Journal of Materials Research , 102 ( 7 ), 796 - 808 . Carl Hanser Verlag ( 2011 ).