In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis

Retrovirology

Volumn 10, Issue 1, 2013, Pages

  Watkins, Richard L ^a   Zou, Wei ^a   Denton, Paul W ^a   Krisko, John F ^a   Foster, John L ^a   Garcia, J V ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

BLT humanized mice; HIV 1; Mutation; Nef; Pathogenesis; Replication

Indexed keywords

CD4 ANTIGEN; NEF PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CD4+ T LYMPHOCYTE; CELL ACTIVITY; CELL LOSS; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; OPEN READING FRAME; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; T CELL DEPLETION; VIRUS IDENTIFICATION; VIRUS PATHOGENESIS; VIRUS REPLICATION; WILD TYPE;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

ANIMALS; ANTIGENS, CD4; DOWN-REGULATION; FRAMESHIFT MUTATION; HIV-1; MICE; MICE, SCID; MUTATION, MISSENSE; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; SEQUENCE DELETION; VIRUS REPLICATION;

EID: 84886484554     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-125     Document Type: Article

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