메뉴 건너뛰기




Volumn 4, Issue , 2007, Pages

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

(16)  Gorry, Paul R a,b,c   McPhee, Dale A b,c,e   Verity, Erin a,d,e   Dyer, Wayne B f,g   Wesselingh, Steven L a,b,c   Learmont, Jennifer f   Sullivan, John S f,g   Roche, Michael a   Zaunders, John J h   Gabuzda, Dana i,j   Crowe, Suzanne M a,c   Mills, John a   Lewin, Sharon R c,k   Brew, Bruce J h   Cunningham, Anthony L l   Churchill, Melissa J a  


Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ANTIGEN P24; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; G PROTEIN COUPLED RECEPTOR; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INDINAVIR; LAMIVUDINE; NEF PROTEIN; NEVIRAPINE; STAVUDINE; ZIDOVUDINE;

EID: 36048974619     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-4-66     Document Type: Review
Times cited : (60)

References (100)
  • 1
    • 33746598200 scopus 로고    scopus 로고
    • HIV vaccines: New frontiers in vaccine development
    • 10.1086/505979 16838241
    • Duerr A Wasserheit JN Corey L HIV vaccines: New frontiers in vaccine development Clin Infect Dis 2006, 43(4);500-511 10.1086/505979 16838241
    • (2006) Clin Infect Dis , vol.43 , Issue.4 , pp. 500-511
    • Duerr, A.1    Wasserheit, J.N.2    Corey, L.3
  • 2
    • 33845207660 scopus 로고    scopus 로고
    • Progress and obstacles in the development of an AIDS vaccine
    • 10.1038/nri1959 17124514
    • Letvin NL Progress and obstacles in the development of an AIDS vaccine Nat Rev Immunol 2006, 6(12);930-939 10.1038/nri1959 17124514
    • (2006) Nat Rev Immunol , vol.6 , Issue.12 , pp. 930-939
    • Letvin, N.L.1
  • 3
    • 33646172660 scopus 로고    scopus 로고
    • HIV vaccines
    • 10.1146/annurev.immunol.24.021605.090605 16551249
    • McMichael AJ HIV vaccines Annu Rev Immunol 2006, 24:227-255 10.1146/ annurev.immunol.24.021605.090605 16551249
    • (2006) Annu Rev Immunol , vol.24 , pp. 227-255
    • McMichael, A.J.1
  • 4
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • 1664601 17132052 10.1371/journal.pmed.0030442
    • Mathers CD Loncar D Projections of global mortality and burden of disease from 2002 to 2030 PLoS Med 2006, 3(11):e442 1664601 17132052 10.1371/journal.pmed.0030442
    • (2006) PLoS Med , vol.3 , Issue.11
    • Mathers, C.D.1    Loncar, D.2
  • 5
    • 0036677041 scopus 로고    scopus 로고
    • Molecular virology and immunology of HIV infection
    • 10.1067/mai.2002.126226 12170257
    • Chinen J Shearer WT Molecular virology and immunology of HIV infection J Allergy Clin Immunol 2002, 110(2);189-198 10.1067/mai.2002.126226 12170257
    • (2002) J Allergy Clin Immunol , vol.110 , Issue.2 , pp. 189-198
    • Chinen, J.1    Shearer, W.T.2
  • 6
    • 0038717548 scopus 로고    scopus 로고
    • Immunopathogenesis and immunotherapy in AIDS virus infections
    • 10.1038/nm0703-861 12835706
    • Letvin NL Walker BD Immunopathogenesis and immunotherapy in AIDS virus infections Nat Med 2003, 9(7):861-866 10.1038/nm0703-861 12835706
    • (2003) Nat Med , vol.9 , Issue.7 , pp. 861-866
    • Letvin, N.L.1    Walker, B.D.2
  • 7
    • 33645558355 scopus 로고    scopus 로고
    • Current progress in the development of HIV vaccines
    • 10.2174/138161206776055859 16515492
    • Spearman P Current progress in the development of HIV vaccines Curr Pharm Des 2006, 12(9)1147-1167 10.2174/138161206776055859 16515492
    • (2006) Curr Pharm Des , vol.12 , Issue.9 , pp. 1147-1167
    • Spearman, P.1
  • 8
    • 0038638590 scopus 로고    scopus 로고
    • HIV vaccines 1983-2003
    • 10.1038/nm0703-874 12835708
    • McMichael AJ Hanke T HIV vaccines 1983-2003 Nat Med 2003, 9(7):874-880 10.1038/nm0703-874 12835708
    • (2003) Nat Med , vol.9 , Issue.7 , pp. 874-880
    • McMichael, A.J.1    Hanke, T.2
  • 9
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • 10.1086/428404 15688278
    • Flynn NM Forthal DN Harro CD Judson FN Mayer KH Para MF Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection J Infect Dis 2005, 191(5);654-665 10.1086/428404 15688278
    • (2005) J Infect Dis , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3    Judson, F.N.4    Mayer, K.H.5    Para, M.F.6
  • 10
    • 24644479045 scopus 로고    scopus 로고
    • HIV-1 virologic and immunologic progression and initiation of antiretroviral therapy among HIV-1-infected subjects in a trial of the efficacy of recombinant glycoprotein 120 vaccine
    • 10.1086/432734 16107949
    • Gilbert PB Ackers ML Berman PW Francis DP Popovic V Hu DJ Heyward WL Sinangil F Shepherd BE Gurwith M HIV-1 virologic and immunologic progression and initiation of antiretroviral therapy among HIV-1-infected subjects in a trial of the efficacy of recombinant glycoprotein 120 vaccine J Infect Dis 2005, 192(6):974-983 10.1086/ 432734 16107949
    • (2005) J Infect Dis , vol.192 , Issue.6 , pp. 974-983
    • Gilbert, P.B.1    Ackers, M.L.2    Berman, P.W.3    Francis, D.P.4    Popovic, V.5    Hu, D.J.6    Heyward, W.L.7    Sinangil, F.8    Shepherd, B.E.9    Gurwith, M.10
  • 12
    • 13944262072 scopus 로고    scopus 로고
    • Lessons from failure--preparing for future HIV-1 vaccine efficacy trials
    • 10.1086/428406 15688276
    • Graham BS Mascola JR Lessons from failure--preparing for future HIV-1 vaccine efficacy trials J Infect Dis 2005, 191(5):647-649 10.1086/428406 15688276
    • (2005) J Infect Dis , vol.191 , pp. 647-649
    • Graham, B.S.1    Mascola, J.R.2
  • 13
    • 4043060710 scopus 로고    scopus 로고
    • Correlates of immune protection in HIV-1 infection: What we know, what we don't know, what we should know
    • 10.1038/nm0804-806 15286782
    • Pantaleo G Koup RA Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know Nat Med 2004, 10(8):806-810 10.1038/nm0804-806 15286782
    • (2004) Nat Med , vol.10 , Issue.8 , pp. 806-810
    • Pantaleo, G.1    Koup, R.A.2
  • 14
    • 3042819783 scopus 로고    scopus 로고
    • Live attenuated HIV vaccines: Pitfalls and prospects
    • 10.1097/00001432-200402000-00004 15090885
    • Whitney JB Ruprecht RM Live attenuated HIV vaccines: Pitfalls and prospects Curr Opin Infect Dis 2004, 17(1):17-26 10.1097/ 00001432-200402000-00004 15090885
    • (2004) Curr Opin Infect Dis , vol.17 , Issue.1 , pp. 17-26
    • Whitney, J.B.1    Ruprecht, R.M.2
  • 15
    • 33748620021 scopus 로고    scopus 로고
    • No vaccine against HIV yet - Are we not perfectly equipped?
    • 1563999 16939652 10.1186/1743-422X-3-60
    • Singh M No vaccine against HIV yet - are we not perfectly equipped? Virol J 2006, 3:60 1563999 16939652 10.1186/1743-422X-3-60
    • (2006) Virol J , vol.3 , pp. 60
    • Singh, M.1
  • 16
    • 30644457180 scopus 로고    scopus 로고
    • A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames
    • 1360091 16398928 10.1186/1742-4690-3-1
    • Klase Z Donio MJ Blauvelt A Marx PA Jeang KT Smith SM A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames Retrovirology 2006, 3:1 1360091 16398928 10.1186/1742-4690-3-1
    • (2006) Retrovirology , vol.3 , pp. 1
    • Klase, Z.1    Donio, M.J.2    Blauvelt, A.3    Marx, P.A.4    Jeang, K.T.5    Smith, S.M.6
  • 17
    • 34250192603 scopus 로고    scopus 로고
    • Antigen-presenting particle technology using inactivated surface-engineered viruses: Induction of immune responses against infectious agents
    • 1885814 17504532 10.1186/1742-4690-4-32
    • Mosca JD Chang YN Williams G Antigen-presenting particle technology using inactivated surface-engineered viruses: Induction of immune responses against infectious agents Retrovirology 2007, 4:32 1885814 17504532 10.1186/1742-4690-4-32
    • (2007) Retrovirology , vol.4 , pp. 32
    • Mosca, J.D.1    Chang, Y.N.2    Williams, G.3
  • 18
    • 0032849066 scopus 로고    scopus 로고
    • Protection by live, attenuated simian immunodeficiency virus against heterologous challenge
    • 112853 10482586
    • Wyand MS Manson K Montefiori DC Lifson JD Johnson RP Desrosiers RC Protection by live, attenuated simian immunodeficiency virus against heterologous challenge J Virol 1999, 73(10):8356-8363 112853 10482586
    • (1999) J Virol , vol.73 , Issue.10 , pp. 8356-8363
    • Wyand, M.S.1    Manson, K.2    Montefiori, D.C.3    Lifson, J.D.4    Johnson, R.P.5    Desrosiers, R.C.6
  • 19
    • 0029951823 scopus 로고    scopus 로고
    • Vaccine protection by a triple deletion mutant of simian immunodeficiency virus
    • 190248 8648707
    • Wyand MS Manson KH Garcia-Moll M Montefiori D Desrosiers RC Vaccine protection by a triple deletion mutant of simian immunodeficiency virus J Virol 1996, 70(6);3724-3733 190248 8648707
    • (1996) J Virol , vol.70 , Issue.6 , pp. 3724-3733
    • Wyand, M.S.1    Manson, K.H.2    Garcia-Moll, M.3    Montefiori, D.4    Desrosiers, R.C.5
  • 20
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
    • 1941 10.1126/science.1470917 1470917
    • Daniel MD Kirchhoff F Czajak SC Sehgal PK Desrosiers RC Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene Science 1992, 258:5090-1938 1941 10.1126/science.1470917 1470917
    • (1992) Science , vol.258 , pp. 1938-1941
    • Daniel, M.D.1    Kirchhoff, F.2    Czajak, S.C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 21
    • 0029652922 scopus 로고
    • Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells
    • 1344 10.1016/S0140-6736(95)92540-6 7752758
    • Almond N Kent K Cranage M Rud E Clarke B Stott EJ Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells Lancet 1995, 345:8961-1342 1344 10.1016/ S0140-6736(95)92540-6 7752758
    • (1995) Lancet , vol.345 , pp. 1342-1344
    • Almond, N.1    Kent, K.2    Cranage, M.3    Rud, E.4    Clarke, B.5    Stott, E.J.6
  • 26
    • 0342505323 scopus 로고    scopus 로고
    • Pathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated Nef
    • 10.1128/JVI.74.4.2038-2045.2000
    • Sawai ET Hamza MS Ye M Shaw KE Luciw PA Pathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated Nef J Virol 2000, 74(4):2038-2045 111683 10644378 10.1128/JVI.74.4.2038-2045.2000
    • (2000) J Virol , vol.74 , Issue.4 , pp. 2038-2045
    • Sawai, E.T.1    Hamza, M.S.2    Ye, M.3    Shaw, K.E.4    Luciw, P.A.5
  • 27
    • 0037462706 scopus 로고    scopus 로고
    • Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation
    • 10.1097/00002030-200301240-00004 12545074
    • Hofmann-Lehmann R Vlasak J Williams AL Chenine AL McClure HM Anderson DC O'Neil S Ruprecht RM Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation Aids 2003, 17(2);157-166 10.1097/00002030-200301240-00004 12545074
    • (2003) Aids , vol.17 , Issue.2 , pp. 157-166
    • Hofmann-Lehmann, R.1    Vlasak, J.2    Williams, A.L.3    Chenine, A.L.4    McClure, H.M.5    Anderson, D.C.6    O'Neil, S.7    Ruprecht, R.M.8
  • 29
    • 30344441124 scopus 로고    scopus 로고
    • Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source
    • 1346882 16379007 10.1128/JVI.80.2.1047-1052.2006
    • Churchill MJ Rhodes DI Learmont JC Sullivan JS Wesselingh SL Cooke IR Deacon NJ Gorry PR Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source J Virol 2006, 80(2):1047-1052 1346882 16379007 10.1128/JVI.80.2.1047-1052.2006
    • (2006) J Virol , vol.80 , Issue.2 , pp. 1047-1052
    • Churchill, M.J.1    Rhodes, D.I.2    Learmont, J.C.3    Sullivan, J.S.4    Wesselingh, S.L.5    Cooke, I.R.6    Deacon, N.J.7    Gorry, P.R.8
  • 33
    • 0028835788 scopus 로고
    • Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
    • 10.1056/NEJM199501263320405 7808489
    • Kirchhoff F Greenough TC Brettler DB Sullivan JL Desrosiers RC Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection N Engl J Med 1995, 332(4):228-232 10.1056/ NEJM199501263320405 7808489
    • (1995) N Engl J Med , vol.332 , Issue.4 , pp. 228-232
    • Kirchhoff, F.1    Greenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 34
    • 20844432390 scopus 로고    scopus 로고
    • Identification of attenuated variants of HIV-1 circulating recombinant form 01Æ that are associated with slow disease progression due to gross genetic alterations in the nef/long terminal repeat sequences
    • 10.1086/430739 15942894
    • Kondo M Shima T Nishizawa M Sudo K Iwamuro S Okabe T Takebe Y Imai M Identification of attenuated variants of HIV-1 circulating recombinant form 01Æ that are associated with slow disease progression due to gross genetic alterations in the nef/long terminal repeat sequences Journal of Infectious Diseases 2005, 192:56-61 10.1086/430739 15942894
    • (2005) Journal of Infectious Diseases , vol.192 , pp. 56-61
    • Kondo, M.1    Shima, T.2    Nishizawa, M.3    Sudo, K.4    Iwamuro, S.5    Okabe, T.6    Takebe, Y.7    Imai, M.8
  • 35
    • 0029846223 scopus 로고    scopus 로고
    • High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection
    • 190845 8892896
    • Mariani R Kirchhoff F Greenough TC Sullivan JL Desrosiers RC Skowronski J High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection J Virol 1996, 70(11);7752-7764 190845 8892896
    • (1996) J Virol , vol.70 , Issue.11 , pp. 7752-7764
    • Mariani, R.1    Kirchhoff, F.2    Greenough, T.C.3    Sullivan, J.L.4    Desrosiers, R.C.5    Skowronski, J.6
  • 36
    • 0033766992 scopus 로고    scopus 로고
    • Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group
    • 110932 11044102 10.1128/JVI.74.22.10581-10588.2000
    • Rhodes DI Ashton L Solomon A Carr A Cooper D Kaldor J Deacon N Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group J Virol 2000, 74(22);10581-10588 110932 11044102 10.1128/JVI.74.22.10581-10588.2000
    • (2000) J Virol , vol.74 , Issue.22 , pp. 10581-10588
    • Rhodes, D.I.1    Ashton, L.2    Solomon, A.3    Carr, A.4    Cooper, D.5    Kaldor, J.6    Deacon, N.7
  • 37
    • 0031979771 scopus 로고    scopus 로고
    • Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor
    • 109585 9557645
    • Salvi R Garbuglia AR Di Caro A Pulciani S Montella F Benedetto A Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor J Virol 1998, 72(5):3646-3657 109585 9557645
    • (1998) J Virol , vol.72 , Issue.5 , pp. 3646-3657
    • Salvi, R.1    Garbuglia, A.R.2    Di Caro, A.3    Pulciani, S.4    Montella, F.5    Benedetto, A.6
  • 42
    • 0033230961 scopus 로고    scopus 로고
    • Identification of a new recipient in the Sydney Blood Bank Cohort: A long-term HIV type 1-infected seroindeterminate individual
    • 10.1089/088922299309946 10555106
    • Rhodes D Solomon A Bolton W Wood J Sullivan J Learmont J Deacon N Identification of a new recipient in the Sydney Blood Bank Cohort: A long-term HIV type 1-infected seroindeterminate individual AIDS Res Hum Retroviruses 1999, 15(16):1433-1439 10.1089/088922299309946 10555106
    • (1999) AIDS Res Hum Retroviruses , vol.15 , Issue.16 , pp. 1433-1439
    • Rhodes, D.1    Solomon, A.2    Bolton, W.3    Wood, J.4    Sullivan, J.5    Learmont, J.6    Deacon, N.7
  • 43
    • 0033994315 scopus 로고    scopus 로고
    • Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo
    • 111962 10756060 10.1128/JVI.74.9.4433-4440.2000
    • Etemad-Moghadam B Sun Y Nicholson EK Fernandes M Liou K Gomila R Lee J Sodroski J Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo J Virol 2000, 74(9):4433-4440 111962 10756060 10.1128/ JVI.74.9.4433-4440.2000
    • (2000) J Virol , vol.74 , Issue.9 , pp. 4433-4440
    • Etemad-Moghadam, B.1    Sun, Y.2    Nicholson, E.K.3    Fernandes, M.4    Liou, K.5    Gomila, R.6    Lee, J.7    Sodroski, J.8
  • 44
    • 20444395434 scopus 로고    scopus 로고
    • Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome
    • 10.1016/j.virol.2005.04.034 15916792
    • Gray L Sterjovski J Churchill M Ellery P Nasr N Lewin SR Crowe SM Wesselingh S Cunningham AL Gorry PR Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome Virology 2005, 337:384-398 10.1016/j.virol.2005.04.034 15916792
    • (2005) Virology , vol.337 , pp. 384-398
    • Gray, L.1    Sterjovski, J.2    Churchill, M.3    Ellery, P.4    Nasr, N.5    Lewin, S.R.6    Crowe, S.M.7    Wesselingh, S.8    Cunningham, A.L.9    Gorry, P.R.10
  • 45
    • 20644447360 scopus 로고    scopus 로고
    • In vivo replication kinetics of a nef-deleted strain of HIV-1
    • 10.1097/01.aids.0000168984.05209.f1 15867504
    • Crowe SM Ho DD Marriott D Brew B Gorry PR Sullivan JS Learmont J Mills J In vivo replication kinetics of a nef-deleted strain of HIV-1 Aids 2005, 19(8);842-843 10.1097/01.aids.0000168984.05209.f1 15867504
    • (2005) Aids , vol.19 , Issue.8 , pp. 842-843
    • Crowe, S.M.1    Ho, D.D.2    Marriott, D.3    Brew, B.4    Gorry, P.R.5    Sullivan, J.S.6    Learmont, J.7    Mills, J.8
  • 46
    • 0030952479 scopus 로고    scopus 로고
    • Decay characteristics of HIV-1-infected compartments during combination therapy
    • 10.1038/387188a0 9144290
    • Perelson AS Essunger P Cao Y Vesanen M Hurley A Saksela K Markowitz M Ho DD Decay characteristics of HIV-1-infected compartments during combination therapy Nature 1997, 387(6629):188-191 10.1038/387188a0 9144290
    • (1997) Nature , vol.387 , Issue.6629 , pp. 188-191
    • Perelson, A.S.1    Essunger, P.2    Cao, Y.3    Vesanen, M.4    Hurley, A.5    Saksela, K.6    Markowitz, M.7    Ho, D.D.8
  • 47
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • 10.1126/science.271.5255.1582 8599114
    • Perelson AS Neumann AU Markowitz M Leonard JM Ho DD HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time Science 1996, 271(5255):1582-1586 10.1126/ science.271.5255.1582 8599114
    • (1996) Science , vol.271 , Issue.5255 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 49
    • 0011419832 scopus 로고    scopus 로고
    • Characterization of viral dynamics in human immunodeficiency virus type 1-infected patients treated with combination antiretroviral therapy: Relationships to host factors, cellular restoration, and virologic end points
    • 10.1086/314670 10068574
    • Wu H Kuritzkes DR McClernon DR Kessler H Connick E Landay A Spear G Heath-Chiozzi M Rousseau F Fox L Spritzler J Leonard JM Lederman MM Characterization of viral dynamics in human immunodeficiency virus type 1-infected patients treated with combination antiretroviral therapy: relationships to host factors, cellular restoration, and virologic end points J Infect Dis 1999, 179(4):799-807 10.1086/314670 10068574
    • (1999) J Infect Dis , vol.179 , Issue.4 , pp. 799-807
    • Wu, H.1    Kuritzkes, D.R.2    McClernon, D.R.3    Kessler, H.4    Connick, E.5    Landay, A.6    Spear, G.7    Heath-Chiozzi, M.8    Rousseau, F.9    Fox, L.10    Spritzler, J.11    Leonard, J.M.12    Lederman, M.M.13
  • 51
    • 0036633807 scopus 로고    scopus 로고
    • Coreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence
    • 136331 12072497 10.1128/JVI.76.14.6966-6973.2002
    • Jekle A Schramm B Jayakumar P Trautner V Schols D De Clercq E Mills J Crowe SM Goldsmith MA Coreceptor phenotype of natural human immunodeficiency virus with nef deleted evolves in vivo, leading to increased virulence J Virol 2002, 76(14):6966-6973 136331 12072497 10.1128/JVI.76.14.6966-6973.2002
    • (2002) J Virol , vol.76 , Issue.14 , pp. 6966-6973
    • Jekle, A.1    Schramm, B.2    Jayakumar, P.3    Trautner, V.4    Schols, D.5    De Clercq, E.6    Mills, J.7    Crowe, S.M.8    Goldsmith, M.A.9
  • 52
    • 85056036796 scopus 로고    scopus 로고
    • Macrophage tropism and cytopathicity of HIV-1 variants isolated sequentially from a long-term survivor infected with nef-deleted virus
    • Gorry PR McPhee DA Wesselingh SL Churchill MJ Macrophage tropism and cytopathicity of HIV-1 variants isolated sequentially from a long-term survivor infected with nef-deleted virus. The Open Microbiology Journal 2007, 1:1-7
    • (2007) The Open Microbiology Journal , vol.1 , pp. 1-7
    • Gorry, P.R.1    McPhee, D.A.2    Wesselingh, S.L.3    Churchill, M.J.4
  • 54
    • 0032933836 scopus 로고    scopus 로고
    • Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: Evidence for a role of the envelope
    • 103909 9882290
    • Ohagen A Ghosh S He J Huang K Chen Y Yuan M Osathanondh R Gartner S Shi B Shaw G Gabuzda D Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope Journal of Virology 1999, 73(2):897-906 103909 9882290
    • (1999) Journal of Virology , vol.73 , Issue.2 , pp. 897-906
    • Ohagen, A.1    Ghosh, S.2    He, J.3    Huang, K.4    Chen, Y.5    Yuan, M.6    Osathanondh, R.7    Gartner, S.8    Shi, B.9    Shaw, G.10    Gabuzda, D.11
  • 55
    • 2942687021 scopus 로고    scopus 로고
    • Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages
    • 10.1128/JVI.78.13.6915-6926.2004
    • Peters PJ Bhattacharya J Hibbitts S Dittmar MT Simmons G Bell J Simmonds P Clapham PR Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages J Virol 2004, 78(13);6915-6926 421670 15194768 10.1128/JVI.78.13.6915-6926.2004
    • (2004) J Virol , vol.78 , pp. 6915-6926
    • Peters, P.J.1    Bhattacharya, J.2    Hibbitts, S.3    Dittmar, M.T.4    Simmons, G.5    Bell, J.6    Simmonds, P.7    Clapham, P.R.8
  • 56
    • 0033589778 scopus 로고    scopus 로고
    • Effect of long-term infection with nef-defective attenuated HIV type 1 on CD4+ and CD8+ T lymphocytes: Increased CD45RO+CD4+ T lymphocytes and limited activation of CD8+ T lymphocytes
    • 10.1089/088922299309801 10580402
    • Zaunders JJ Geczy AF Dyer WB McIntyre LB Cooley MA Ashton LJ Raynes-Greenow CH Learmont J Cooper DA Sullivan JS Effect of long-term infection with nef-defective attenuated HIV type 1 on CD4+ and CD8+ T lymphocytes: Increased CD45RO+CD4+ T lymphocytes and limited activation of CD8+ T lymphocytes AIDS Res Hum Retroviruses 1999, 15(17):1519-1527 10.1089/088922299309801 10580402
    • (1999) AIDS Res Hum Retroviruses , vol.15 , Issue.17 , pp. 1519-1527
    • Zaunders, J.J.1    Geczy, A.F.2    Dyer, W.B.3    McIntyre, L.B.4    Cooley, M.A.5    Ashton, L.J.6    Raynes-Greenow, C.H.7    Learmont, J.8    Cooper, D.A.9    Sullivan, J.S.10
  • 57
    • 0031010762 scopus 로고    scopus 로고
    • Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI
    • 191662 191662 9151834
    • Chun TW Chadwick K Margolick J Siliciano RF Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI J Virol 1997, 71(6):4436-4444 191662 9151834
    • (1997) J Virol , vol.71 , Issue.6 , pp. 4436-4444
    • Chun, T.W.1    Chadwick, K.2    Margolick, J.3    Siliciano, R.F.4
  • 58
    • 0033617547 scopus 로고    scopus 로고
    • Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs
    • Harouse JM Gettie A Tan RC Blanchard J Cheng-Mayer C Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs Science, 1999 284(5415):816-819 10.1126/science.284.5415.816 10221916
    • (1999) Science , vol.284 , Issue.5415 , pp. 816-819
    • Harouse, J.M.1    Gettie, A.2    Tan, R.C.3    Blanchard, J.4    Cheng-Mayer, C.5
  • 59
    • 0031774861 scopus 로고    scopus 로고
    • Human lymphoblastoid CD4(+) T cells become permissive to macrophage-tropic strains of human immunodeficiency virus type 1 after passage into severe combined immunodeficient mice through in vivo upregulation of CCR5: In vivo dynamics of CD4(+) T-cell differentiation in pathogenesis of AIDS
    • 110622 9811784
    • Lapenta C Parlato S Spada M Santini SM Rizza P Logozzi M Proietti E Belardelli F Fais S Human lymphoblastoid CD4(+) T cells become permissive to macrophage-tropic strains of human immunodeficiency virus type 1 after passage into severe combined immunodeficient mice through in vivo upregulation of CCR5: In vivo dynamics of CD4(+) T-cell differentiation in pathogenesis of AIDS J Virol 1998, 72(12):10323-10327 110622 9811784
    • (1998) J Virol , vol.72 , Issue.12 , pp. 10323-10327
    • Lapenta, C.1    Parlato, S.2    Spada, M.3    Santini, S.M.4    Rizza, P.5    Logozzi, M.6    Proietti, E.7    Belardelli, F.8    Fais, S.9
  • 60
    • 0025160079 scopus 로고
    • Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals
    • 54471 2385584 10.1073/pnas.87.16.6058
    • Schnittman SM Lane HC Greenhouse J Justement JS Baseler M Fauci AS Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals Proc Natl Acad Sci U S A 1990, 87(16):6058-6062 54471 2385584 10.1073/pnas.87.16.6058
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.16 , pp. 6058-6062
    • Schnittman, S.M.1    Lane, H.C.2    Greenhouse, J.3    Justement, J.S.4    Baseler, M.5    Fauci, A.S.6
  • 61
    • 33646441497 scopus 로고    scopus 로고
    • Decimated or missing in action: CD4+ T cells as targets and effectors in the pathogenesis of primary HIV infection
    • 10.1007/s11904-006-0002-5 16522253
    • Kelleher AD Zaunders JJ Decimated or missing in action: CD4+ T cells as targets and effectors in the pathogenesis of primary HIV infection Curr HIV/AIDS Rep 2006, 3(1):5-12 10.1007/s11904-006-0002-5 16522253
    • (2006) Curr HIV/AIDS Rep , vol.3 , Issue.1 , pp. 5-12
    • Kelleher, A.D.1    Zaunders, J.J.2
  • 62
    • 0033503076 scopus 로고    scopus 로고
    • Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: Partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia
    • 10.1086/314880 10395845
    • Zaunders JJ Cunningham PH Kelleher AD Kaufmann GR Jaramillo AB Wright R Smith D Grey P Vizzard J Carr A Cooper DA Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia J Infect Dis 1999, 180(2):320-329 10.1086/314880 10395845
    • (1999) J Infect Dis , vol.180 , Issue.2 , pp. 320-329
    • Zaunders, J.J.1    Cunningham, P.H.2    Kelleher, A.D.3    Kaufmann, G.R.4    Jaramillo, A.B.5    Wright, R.6    Smith, D.7    Grey, P.8    Vizzard, J.9    Carr, A.10    Cooper, D.A.11
  • 63
    • 0033647217 scopus 로고    scopus 로고
    • The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS
    • 10.1034/j.1600-065X.2000.17710.x 11138790
    • O'Brien SJ Moore JP The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS Immunol Rev 2000, 177:99-111 10.1034/j.1600-065X.2000.17710.x 11138790
    • (2000) Immunol Rev , vol.177 , pp. 99-111
    • O'Brien, S.J.1    Moore, J.P.2
  • 64
    • 0031806468 scopus 로고    scopus 로고
    • Influence of host genes on HIV-1 disease progression
    • 9619442
    • Roger M Influence of host genes on HIV-1 disease progression Faseb J 1998, 12(9):625-632 9619442
    • (1998) Faseb J , vol.12 , Issue.9 , pp. 625-632
    • Roger, M.1
  • 65
    • 0034304597 scopus 로고    scopus 로고
    • T cell depletion in HIV-1 infection: How CD4+ T cells go out of stock
    • 10.1038/79724 11017098
    • Hazenberg MD Hamann D Schuitemaker H Miedema F T cell depletion in HIV-1 infection: How CD4+ T cells go out of stock Nat Immunol 2000, 1(4):285-289 10.1038/79724 11017098
    • (2000) Nat Immunol , vol.1 , Issue.4 , pp. 285-289
    • Hazenberg, M.D.1    Hamann, D.2    Schuitemaker, H.3    Miedema, F.4
  • 66
    • 0035912232 scopus 로고    scopus 로고
    • The dynamics of CD4+ T-cell depletion in HIV disease
    • 10.1038/35073648 11309627
    • McCune JM The dynamics of CD4+ T-cell depletion in HIV disease Nature 2001, 410(6831):974-979 10.1038/35073648 11309627
    • (2001) Nature , vol.410 , Issue.6831 , pp. 974-979
    • McCune, J.M.1
  • 67
    • 0038618867 scopus 로고    scopus 로고
    • Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys
    • 156171 12768002 10.1128/JVI.77.12.6823-6835.2003
    • Alexander L Illyinskii PO Lang SM Means RE Lifson J Mansfield K Desrosiers RC Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys J Virol 2003, 77(12):6823-6835 156171 12768002 10.1128/ JVI.77.12.6823-6835.2003
    • (2003) J Virol , vol.77 , Issue.12 , pp. 6823-6835
    • Alexander, L.1    Illyinskii, P.O.2    Lang, S.M.3    Means, R.E.4    Lifson, J.5    Mansfield, K.6    Desrosiers, R.C.7
  • 68
    • 33750035813 scopus 로고    scopus 로고
    • Transcriptional activity of blood-and cerebrospinal fluid-derived nef/ long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia
    • 10.1080/13550280600827369 16877303
    • Churchill MJ Figueiredo A Cowley D Gray L Purcell DF Sullivan JS McPhee DA Wesselingh SL Brew BJ Gorry PR Transcriptional activity of blood-and cerebrospinal fluid-derived nef/long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia J Neurovirol 2006, 12(3);219-228 10.1080/13550280600827369 16877303
    • (2006) J Neurovirol , vol.12 , Issue.3 , pp. 219-228
    • Churchill, M.J.1    Figueiredo, A.2    Cowley, D.3    Gray, L.4    Purcell, D.F.5    Sullivan, J.S.6    McPhee, D.A.7    Wesselingh, S.L.8    Brew, B.J.9    Gorry, P.R.10
  • 69
    • 0034030611 scopus 로고    scopus 로고
    • Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G
    • 111883 10729149 10.1128/JVI.74.8.3740-3751.2000
    • Jeeninga RE Hoogenkamp M Armand-Ugon M de Baar M Verhoef K Berkhout B Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G J Virol 2000, 74(8);3740-3751 111883 10729149 10.1128/ JVI.74.8.3740-3751.2000
    • (2000) J Virol , vol.74 , Issue.8 , pp. 3740-3751
    • Jeeninga, R.E.1    Hoogenkamp, M.2    Armand-Ugon, M.3    de Baar, M.4    Verhoef, K.5    Berkhout, B.6
  • 70
    • 0031876686 scopus 로고    scopus 로고
    • Restricted HIV-1 infection of human astrocytes: Potential role of nef in the regulation of virus replication
    • Gorry P Purcell D Howard J McPhee D Restricted HIV-1 infection of human astrocytes: Potential role of nef in the regulation of virus replication Journal of Neurovirology 1998, 4(4):377-386 9718129
    • (1998) Journal of Neurovirology , vol.4 , Issue.4 , pp. 377-386
    • Gorry, P.1    Purcell, D.2    Howard, J.3    McPhee, D.4
  • 71
    • 0030917941 scopus 로고    scopus 로고
    • In vivo sequence variability of human immunodeficiency virus type 1 envelope gp120: Association of V2 extension with slow disease progression
    • 191717 9188549
    • Shioda T Oka S Xin X Liu H Harukuni R Kurotani A Fukushima M Hasan MK Shiino T Takebe Y Iwamoto A Nagai Y In vivo sequence variability of human immunodeficiency virus type 1 envelope gp120: Association of V2 extension with slow disease progression J Virol 1997, 71(7):4871-4881 191717 9188549
    • (1997) J Virol , vol.71 , Issue.7 , pp. 4871-4881
    • Shioda, T.1    Oka, S.2    Xin, X.3    Liu, H.4    Harukuni, R.5    Kurotani, A.6    Fukushima, M.7    Hasan, M.K.8    Shiino, T.9    Takebe, Y.10    Iwamoto, A.11    Nagai, Y.12
  • 72
    • 0034054474 scopus 로고    scopus 로고
    • HIV-1 strains from a cohort of American subjects reveal the presence of a V2 region extension unique to slow progressors and non-progressors
    • 10.1097/00002030-200002180-00002 10716496
    • Wang B Spira TJ Owen S Lal RB Saksena NK HIV-1 strains from a cohort of American subjects reveal the presence of a V2 region extension unique to slow progressors and non-progressors Aids 2000, 14(3);213-223 10.1097/ 00002030-200002180-00002 10716496
    • (2000) Aids , vol.14 , Issue.3 , pp. 213-223
    • Wang, B.1    Spira, T.J.2    Owen, S.3    Lal, R.B.4    Saksena, N.K.5
  • 74
    • 0036785579 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by a two-amino-acid insertion in HIV-1 Vif from a nonprogressing mother and child
    • 136583 12239333 10.1128/JVI.76.20.10533-10539.2002
    • Alexander L Aquino-DeJesus MJ Chan M Andiman WA Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by a two-amino-acid insertion in HIV-1 Vif from a nonprogressing mother and child J Virol 2002, 76(20);10533-10539 136583 12239333 10.1128/ JVI.76.20.10533-10539.2002
    • (2002) J Virol , vol.76 , Issue.20 , pp. 10533-10539
    • Alexander, L.1    Aquino-DeJesus, M.J.2    Chan, M.3    Andiman, W.A.4
  • 75
    • 0031900150 scopus 로고    scopus 로고
    • Persistent antibody responses but declining cytotoxic T-lymphocyte responses to multiple human immunodeficiency virus type 1 antigens in a long-term nonprogressing individual with a defective p17 proviral sequence and no detectable viral RNA expression
    • 109859 9525685
    • Binley JM Jin X Huang Y Zhang L Cao Y Ho DD Moore JP Persistent antibody responses but declining cytotoxic T-lymphocyte responses to multiple human immunodeficiency virus type 1 antigens in a long-term nonprogressing individual with a defective p17 proviral sequence and no detectable viral RNA expression J Virol 1998, 72(4):3472-3474 109859 9525685
    • (1998) J Virol , vol.72 , pp. 3472-3474
    • Binley, J.M.1    Jin, X.2    Huang, Y.3    Zhang, L.4    Cao, Y.5    Ho, D.D.6    Moore, J.P.7
  • 76
    • 0030247883 scopus 로고    scopus 로고
    • Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: In vivo evolution of vpr quasispecies in blood and plasma
    • 10.1006/viro.1996.0471 8806556
    • Wang B Ge YC Palasanthiran P Xiang SH Ziegler J Dwyer DE Randle C Dowton D Cunningham A Saksena NK Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: in vivo evolution of vpr quasispecies in blood and plasma Virology 1996, 223(1);224-232 10.1006/viro.1996.0471 8806556
    • (1996) Virology , vol.223 , Issue.1 , pp. 224-232
    • Wang, B.1    Ge, Y.C.2    Palasanthiran, P.3    Xiang, S.H.4    Ziegler, J.5    Dwyer, D.E.6    Randle, C.7    Dowton, D.8    Cunningham, A.9    Saksena, N.K.10
  • 77
    • 0034128313 scopus 로고    scopus 로고
    • Comparison of proviral accessory genes between long-term nonprogressors and progressors of human immunodeficiency virus type 1 infection
    • 10.1007/s007050050692 10881687
    • Yamada T Iwamoto A Comparison of proviral accessory genes between long-term nonprogressors and progressors of human immunodeficiency virus type 1 infection Arch Virol 2000, 145(5);1021-1027 10.1007/s007050050692 10881687
    • (2000) Arch Virol , vol.145 , Issue.5 , pp. 1021-1027
    • Yamada, T.1    Iwamoto, A.2
  • 78
    • 0029019603 scopus 로고
    • Defective accessory genes in a human immunodeficiency virus type 1-infected long-term survivor lacking recoverable virus
    • 189160 7769682
    • Michael NL Chang G d'Arcy LA Ehrenberg PK Mariani R Busch MP Birx DL Schwartz DH Defective accessory genes in a human immunodeficiency virus type 1-infected long-term survivor lacking recoverable virus J Virol 1995, 69(7):4228-4236 189160 7769682
    • (1995) J Virol , vol.69 , Issue.7 , pp. 4228-4236
    • Michael, N.L.1    Chang, G.2    d'Arcy, L.A.3    Ehrenberg, P.K.4    Mariani, R.5    Busch, M.P.6    Birx, D.L.7    Schwartz, D.H.8
  • 79
    • 0030586764 scopus 로고    scopus 로고
    • Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev
    • 10.1006/viro.1996.0439 8806526
    • Hua J Caffrey JJ Cullen BR Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev Virology 1996, 222(2);423-429 10.1006/viro.1996.0439 8806526
    • (1996) Virology , vol.222 , Issue.2 , pp. 423-429
    • Hua, J.1    Caffrey, J.J.2    Cullen, B.R.3
  • 80
    • 0242342409 scopus 로고    scopus 로고
    • An in vivo replication-important function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection
    • 10.1074/jbc.M307546200 12947089
    • Smith SM Pentlicky S Klase Z Singh M Neuveut C Lu CY Reitz MS Jr. Yarchoan R Marx PA Jeang KT An in vivo replication-important function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection J Biol Chem 2003, 278(45):44816-44825 10.1074/jbc.M307546200 12947089
    • (2003) J Biol Chem , vol.278 , Issue.45 , pp. 44816-44825
    • Smith, S.M.1    Pentlicky, S.2    Klase, Z.3    Singh, M.4    Neuveut, C.5    Lu, C.Y.6    Reitz Jr., M.S.7    Yarchoan, R.8    Marx, P.A.9    Jeang, K.T.10
  • 81
    • 34547801169 scopus 로고    scopus 로고
    • Persistence of attenuated HIV-1 rev alleles in an epidemiologically linked cohort of long-term survivors infected with nef-deleted virus
    • 1933581 17601342 10.1186/1742-4690-4-43
    • Churchill M Chiavaroli L Wesselingh SL Gorry PR Persistence of attenuated HIV-1 rev alleles in an epidemiologically linked cohort of long-term survivors infected with nef-deleted virus Retrovirology 2007, 4:43 1933581 17601342 10.1186/1742-4690-4-43
    • (2007) Retrovirology , vol.4 , pp. 43
    • Churchill, M.1    Chiavaroli, L.2    Wesselingh, S.L.3    Gorry, P.R.4
  • 83
    • 10244232806 scopus 로고    scopus 로고
    • Incidence immunoassay for distinguishing recent from established HIV-1 infection in therapy-naive populations
    • 10.1097/00002030-200411190-00005 15577537
    • Wilson KM Johnson EI Croom HA Richards KM Doughty L Cunningham PH Kemp BE Branson BM Dax EM Incidence immunoassay for distinguishing recent from established HIV-1 infection in therapy-naive populations Aids 2004, 18(17):2253-2259 10.1097/00002030-200411190-00005 15577537
    • (2004) Aids , vol.18 , Issue.17 , pp. 2253-2259
    • Wilson, K.M.1    Johnson, E.I.2    Croom, H.A.3    Richards, K.M.4    Doughty, L.5    Cunningham, P.H.6    Kemp, B.E.7    Branson, B.M.8    Dax, E.M.9
  • 84
    • 0032505017 scopus 로고    scopus 로고
    • Neutralizing antibodies are positively associated with CD4+ T-cell counts and T-cell function in long-term AIDS-free infection
    • 10.1097/00002030-199813000-00005 9764777
    • Carotenuto P Looij D Keldermans L de Wolf F Goudsmit J Neutralizing antibodies are positively associated with CD4+ T-cell counts and T-cell function in long-term AIDS-free infection Aids 1998, 12(13):1591-1600 10.1097/00002030-199813000-00005 9764777
    • (1998) Aids , vol.12 , Issue.13 , pp. 1591-1600
    • Carotenuto, P.1    Looij, D.2    Keldermans, L.3    de Wolf, F.4    Goudsmit, J.5
  • 86
    • 0030856310 scopus 로고    scopus 로고
    • Augmented serum neutralizing activity against primary human immunodeficiency virus type 1 (HIV-1) isolates in two groups of HIV-1-infected long-term nonprogressors
    • 9359717
    • Zhang YJ Fracasso C Fiore JR Bjorndal A Angarano G Gringeri A Fenyo EM Augmented serum neutralizing activity against primary human immunodeficiency virus type 1 (HIV-1) isolates in two groups of HIV-1-infected long-term nonprogressors J Infect Dis 1997, 176(5):1180-1187 9359717
    • (1997) J Infect Dis , vol.176 , Issue.5 , pp. 1180-1187
    • Zhang, Y.J.1    Fracasso, C.2    Fiore, J.R.3    Bjorndal, A.4    Angarano, G.5    Gringeri, A.6    Fenyo, E.M.7
  • 88
    • 0036374965 scopus 로고    scopus 로고
    • Protection by intranasal immunization of a nef-deleted, nonpathogenic SHIV against intravaginal challenge with a heterologous pathogenic SHIV
    • 10.1006/viro.2002.1440 12127792
    • Enose Y Ui M Miyake A Suzuki H Uesaka H Kuwata T Kunisawa J Kiyono H Takahashi H Miura T Hayami M Protection by intranasal immunization of a nef-deleted, nonpathogenic SHIV against intravaginal challenge with a heterologous pathogenic SHIV Virology 2002, 298 (2):306-316 10.1006/ viro.2002.1440 12127792
    • (2002) Virology , vol.298 , Issue.2 , pp. 306-316
    • Enose, Y.1    Ui, M.2    Miyake, A.3    Suzuki, H.4    Uesaka, H.5    Kuwata, T.6    Kunisawa, J.7    Kiyono, H.8    Takahashi, H.9    Miura, T.10    Hayami, M.11
  • 89
    • 15644374365 scopus 로고    scopus 로고
    • Protection of monkeys vaccinated with vpr- and/or nef-defective simian immunodeficiency virus strain mac/human immunodeficiency virus type 1 chimeric viruses: A potential candidate live-attenuated human AIDS vaccine
    • 9152414
    • Igarashi T Ami Y Yamamoto H Shibata R Kuwata T Mukai R Shinohara K Komatsu T Adachi A Hayami M Protection of monkeys vaccinated with vpr- and/or nef-defective simian immunodeficiency virus strain mac/human immunodeficiency virus type 1 chimeric viruses: A potential candidate live-attenuated human AIDS vaccine J Gen Virol 1997, 78(Pt 5):985-989 9152414
    • (1997) J Gen Virol , vol.78 , Issue.PART 5 , pp. 985-989
    • Igarashi, T.1    Ami, Y.2    Yamamoto, H.3    Shibata, R.4    Kuwata, T.5    Mukai, R.6    Shinohara, K.7    Komatsu, T.8    Adachi, A.9    Hayami, M.10
  • 90
    • 0036398415 scopus 로고    scopus 로고
    • Immunization of macaques with live simian human immunodeficiency virus (SHIV) vaccines conferred protection against AIDS induced by homologous and heterologous SHIVs and simian immunodeficiency virus
    • 10.1006/viro.2002.1544 12359422
    • Kumar A Mukherjee S Shen J Buch S Li Z Adany I Liu Z Zhuge W Piatak M Jr. Lifson J McClure H Narayan O Immunization of macaques with live simian human immunodeficiency virus (SHIV) vaccines conferred protection against AIDS induced by homologous and heterologous SHIVs and simian immunodeficiency virus Virology 2002, 301(2):189-205 10.1006/ viro.2002.1544 12359422
    • (2002) Virology , vol.301 , Issue.2 , pp. 189-205
    • Kumar, A.1    Mukherjee, S.2    Shen, J.3    Buch, S.4    Li, Z.5    Adany, I.6    Liu, Z.7    Zhuge, W.8    Piatak Jr., M.9    Lifson, J.10    McClure, H.11    Narayan, O.12
  • 91
    • 0030589259 scopus 로고    scopus 로고
    • Neutralizing and infection-enhancing antibody responses do not correlate with the differential pathogenicity of SIVmac239delta3 in adult and infant rhesus monkeys
    • 8955203
    • Montefiori DC Baba TW Li A Bilska M Ruprecht RM Neutralizing and infection-enhancing antibody responses do not correlate with the differential pathogenicity of SIVmac239delta3 in adult and infant rhesus monkeys J Immunol 1996, 157(12):5528-5535 8955203
    • (1996) J Immunol , vol.157 , Issue.12 , pp. 5528-5535
    • Montefiori, D.C.1    Baba, T.W.2    Li, A.3    Bilska, M.4    Ruprecht, R.M.5
  • 92
    • 0034633780 scopus 로고    scopus 로고
    • Characterization of immune escape viruses from a macaque immunized with live-virus vaccine and challenged with pathogenic SHIVKU-1
    • 10.1089/088922200750006092 11054270
    • Stipp HL Kumar A Narayan O Characterization of immune escape viruses from a macaque immunized with live-virus vaccine and challenged with pathogenic SHIVKU-1 AIDS Res Hum Retroviruses 2000, 16(15):1573-1580 10.1089/088922200750006092 11054270
    • (2000) AIDS Res Hum Retroviruses , vol.16 , Issue.15 , pp. 1573-1580
    • Stipp, H.L.1    Kumar, A.2    Narayan, O.3
  • 94
    • 33645288761 scopus 로고    scopus 로고
    • Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells
    • 10.1038/ni1302 16429138
    • Qiao X He B Chiu A Knowles DM Chadburn A Cerutti A Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells Nat Immunol 2006, 7(3):302-310 10.1038/ni1302 16429138
    • (2006) Nat Immunol , vol.7 , Issue.3 , pp. 302-310
    • Qiao, X.1    He, B.2    Chiu, A.3    Knowles, D.M.4    Chadburn, A.5    Cerutti, A.6
  • 95
    • 0031664158 scopus 로고    scopus 로고
    • Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: A predominant gag-specific response is associated with nonprogressive infection
    • 9806028
    • Pontesilli O Klein MR Kerkhof-Garde SR Pakker NG de Wolf F Schuitemaker H Miedema F Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection J Infect Dis 1998, 178(4):1008-1018 9806028
    • (1998) J Infect Dis , vol.178 , Issue.4 , pp. 1008-1018
    • Pontesilli, O.1    Klein, M.R.2    Kerkhof-Garde, S.R.3    Pakker, N.G.4    de Wolf, F.5    Schuitemaker, H.6    Miedema, F.7
  • 97
    • 33847176918 scopus 로고    scopus 로고
    • CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients
    • 1865944 17182686 10.1128/JVI.01847-06
    • Geldmacher C Currier JR Herrmann E Haule A Kuta E McCutchan F Njovu L Geis S Hoffmann O Maboko L Williamson C Birx D Meyerhans A Cox J Hoelscher M CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients J Virol 2007, 81(5):2440-2448 1865944 17182686 10.1128/JVI.01847-06
    • (2007) J Virol , vol.81 , Issue.5 , pp. 2440-2448
    • Geldmacher, C.1    Currier, J.R.2    Herrmann, E.3    Haule, A.4    Kuta, E.5    McCutchan, F.6    Njovu, L.7    Geis, S.8    Hoffmann, O.9    Maboko, L.10    Williamson, C.11    Birx, D.12    Meyerhans, A.13    Cox, J.14    Hoelscher, M.15
  • 98
    • 0032888972 scopus 로고    scopus 로고
    • Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1
    • 103850 9847349
    • Dyer WB Ogg GS Demoitie MA Jin X Geczy AF Rowland-Jones SL McMichael AJ Nixon DF Sullivan JS Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1 J Virol 1999, 73(1):436-443 103850 9847349
    • (1999) J Virol , vol.73 , Issue.1 , pp. 436-443
    • Dyer, W.B.1    Ogg, G.S.2    Demoitie, M.A.3    Jin, X.4    Geczy, A.F.5    Rowland-Jones, S.L.6    McMichael, A.J.7    Nixon, D.F.8    Sullivan, J.S.9
  • 99
    • 0030785330 scopus 로고    scopus 로고
    • Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection
    • 10.1097/00002030-199713000-00004 9365760
    • Dyer WB Geczy AF Kent SJ McIntyre LB Blasdall SA Learmont JC Sullivan JS Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection Aids 1997, 11(13);1565-1574 10.1097/00002030-199713000-00004 9365760
    • (1997) Aids , vol.11 , Issue.13 , pp. 1565-1574
    • Dyer, W.B.1    Geczy, A.F.2    Kent, S.J.3    McIntyre, L.B.4    Blasdall, S.A.5    Learmont, J.C.6    Sullivan, J.S.7
  • 100
    • 0036392037 scopus 로고    scopus 로고
    • Correlates of antiviral immune restoration in acute and chronic HIV type 1 infection: Sustained viral suppression and normalization of T cell subsets
    • 10.1089/08892220260235362 12396452
    • Dyer WB Kuipers H Coolen MW Geczy AF Forrester J Workman C Sullivan JS Correlates of antiviral immune restoration in acute and chronic HIV type 1 infection: sustained viral suppression and normalization of T cell subsets AIDS Res Hum Retroviruses 2002, 18(14):999-1010 10.1089/ 08892220260235362 12396452
    • (2002) AIDS Res Hum Retroviruses , vol.18 , Issue.14 , pp. 999-1010
    • Dyer, W.B.1    Kuipers, H.2    Coolen, M.W.3    Geczy, A.F.4    Forrester, J.5    Workman, C.6    Sullivan, J.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.