메뉴 건너뛰기




Volumn 490, Issue 7419, 2012, Pages 283-289

HIV-infected T cells are migratory vehicles for viral dissemination

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

EID: 84867329009     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11398     Document Type: Article
Times cited : (259)

References (40)
  • 1
    • 79551578453 scopus 로고    scopus 로고
    • Early events in sexual transmission of HIV and SIV and opportunities for interventions
    • Haase, A. T. Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annu. Rev. Med. 62, 127-139 (2011).
    • (2011) Annu. Rev. Med. , vol.62 , pp. 127-139
    • Haase, A.T.1
  • 2
    • 54149119141 scopus 로고    scopus 로고
    • Avoiding the void: Cell-to-cell spread of human viruses
    • Sattentau, Q. Avoiding the void: cell-to-cell spread of human viruses. Nature Rev. Microbiol. 6, 815-826 (2008).
    • (2008) Nature Rev. Microbiol. , vol.6 , pp. 815-826
    • Sattentau, Q.1
  • 3
    • 80052555420 scopus 로고    scopus 로고
    • Different patterns of peripheral migration bymemoryCD41 and CD81 T cells
    • Gebhardt, T. et al. Different patterns of peripheral migration bymemoryCD41 and CD81 T cells. Nature 477, 216-219 (2011).
    • (2011) Nature , vol.477 , pp. 216-219
    • Gebhardt, T.1
  • 4
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel, T. R., Henrickson, S. E. & von Andrian, U. H. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature427, 154-159 (2004).
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1    Henrickson, S.E.2    Von Andrian, U.H.3
  • 5
    • 33750705617 scopus 로고    scopus 로고
    • Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1
    • Melkus, M. W. et al. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nature Med. 12, 1316-1322 (2006).
    • (2006) Nature Med. , vol.12 , pp. 1316-1322
    • Melkus, M.W.1
  • 6
    • 38849136442 scopus 로고    scopus 로고
    • Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice
    • Denton, P. W. et al. Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice. PLoS Med. 5, e16 (2008).
    • (2008) PLoS Med. , vol.5
    • Denton, P.W.1
  • 7
    • 34247392343 scopus 로고    scopus 로고
    • Intrarectal transmission, systemic infection, andCD41Tcelldepletion in humanized mice infected with HIV-1
    • Sun, Z. et al. Intrarectal transmission, systemic infection, andCD41Tcelldepletion in humanized mice infected with HIV-1. J. Exp. Med. 204, 705-714 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 705-714
    • Sun, Z.1
  • 8
    • 67650410026 scopus 로고    scopus 로고
    • Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice
    • Brainard, D. M. et al. Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice. J. Virol. 83, 7305-7321 (2009).
    • (2009) J. Virol. , vol.83 , pp. 7305-7321
    • Brainard, D.M.1
  • 9
    • 0242551584 scopus 로고    scopus 로고
    • Homing and cellular traffic in lymph nodes
    • von Andrian, U. H. & Mempel, T. R. Homing and cellular traffic in lymph nodes. Nature Rev. Immunol. 3, 867-878 (2003).
    • (2003) Nature Rev. Immunol. , vol.3 , pp. 867-878
    • Von Andrian, U.H.1    Mempel, T.R.2
  • 10
    • 33947372536 scopus 로고    scopus 로고
    • CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo
    • Worbs, T., Mempel, T. R., Bolter, J., von Andrian, U. H. & Forster, R. CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J. Exp. Med. 204, 489-495 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 489-495
    • Worbs, T.1    Mempel, T.R.2    Bolter, J.3    Von Andrian, U.H.4    Forster, R.5
  • 11
    • 33845455093 scopus 로고    scopus 로고
    • Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
    • Bajénoff, M. et al. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 25, 989-1001 (2006).
    • (2006) Immunity , vol.25 , pp. 989-1001
    • Bajénoff, M.1
  • 12
    • 17444413400 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism
    • Schindler, M., Munch, J. & Kirchhoff, F. Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism. J. Virol. 79, 5489-5498 (2005).
    • (2005) J. Virol. , vol.79 , pp. 5489-5498
    • Schindler, M.1    Munch, J.2    Kirchhoff, F.3
  • 13
    • 0029793620 scopus 로고    scopus 로고
    • CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu env and nef
    • Chen, B. K., Gandhi, R. T. & Baltimore, D.CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef. J. Virol. 70, 6044-6053 (1996).
    • (1996) J. Virol. , vol.70 , pp. 6044-6053
    • Chen, B.K.1    Gandhi, R.T.2    Baltimore, D.3
  • 14
    • 0032742547 scopus 로고    scopus 로고
    • Sexual transmission and propagation of SIV and HIV in resting and activated CD41 T cells
    • Zhang, Z. et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD41 T cells. Science 286, 1353-1357 (1999).
    • (1999) Science , vol.286 , pp. 1353-1357
    • Zhang, Z.1
  • 15
    • 68549123450 scopus 로고    scopus 로고
    • HIV-1 Nef interferes with host cell motility by deregulation of Cofilin
    • Stolp, B. et al. HIV-1 Nef interferes with host cell motility by deregulation of Cofilin. Cell Host Microbe 6, 174-186 (2009).
    • (2009) Cell Host Microbe , vol.6 , pp. 174-186
    • Stolp, B.1
  • 16
    • 77649228424 scopus 로고    scopus 로고
    • HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes
    • Nobile, C. et al. HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes. J. Virol. 84, 2282-2293 (2010).
    • (2010) J. Virol. , vol.84 , pp. 2282-2293
    • Nobile, C.1
  • 17
    • 24744465855 scopus 로고    scopus 로고
    • HLA-A2 downregulation on primary human macrophages infected with an M-tropic EGFPtagged HIV-1 reporter virus
    • Brown, A., Gartner, S., Kawano, T., Benoit, N. & Cheng-Mayer, C. HLA-A2 downregulation on primary human macrophages infected with an M-tropic EGFPtagged HIV-1 reporter virus. J. Leukoc. Biol. 78, 675-685 (2005).
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 675-685
    • Brown, A.1    Gartner, S.2    Kawano, T.3    Benoit, N.4    Cheng-Mayer, C.5
  • 18
    • 77954668607 scopus 로고    scopus 로고
    • Tetherin restricts productive HIV-1 cell-to-cell transmission
    • Casartelli, N. et al. Tetherin restricts productive HIV-1 cell-to-cell transmission. PLoS Pathog. 6, e1000955 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Casartelli, N.1
  • 19
    • 78449233400 scopus 로고    scopus 로고
    • Nucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cells
    • Llewellyn, G. N., Hogue, I. B., Grover, J. R. & Ono, A. Nucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cells. PLoS Pathog. 6, e1001167 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Llewellyn, G.N.1    Hogue, I.B.2    Grover, J.R.3    Ono, A.4
  • 20
    • 1642540589 scopus 로고    scopus 로고
    • HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse
    • Jolly, C., Kashefi, K., Hollinshead, M. & Sattentau, Q. J. HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse. J. Exp. Med. 199, 283-293 (2004).
    • (2004) J. Exp. Med. , vol.199 , pp. 283-293
    • Jolly, C.1    Kashefi, K.2    Hollinshead, M.3    Sattentau, Q.J.4
  • 21
    • 36049037370 scopus 로고    scopus 로고
    • Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Envdependent neutralization-resistant virological synapses
    • Chen, P., Hubner, W., Spinelli, M. A. & Chen, B. K. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Envdependent neutralization-resistant virological synapses. J. Virol. 81, 12582-12595 (2007).
    • (2007) J. Virol. , vol.81 , pp. 12582-12595
    • Chen, P.1    Hubner, W.2    Spinelli, M.A.3    Chen, B.K.4
  • 22
    • 63449126562 scopus 로고    scopus 로고
    • Quantitative 3D video microscopy of HIV transfer across T cell virological synapses
    • Hübner, W. et al. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science 323, 1743-1747 (2009).
    • (2009) Science , vol.323 , pp. 1743-1747
    • Hübner, W.1
  • 23
    • 66149137185 scopus 로고    scopus 로고
    • Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses
    • Rudnicka, D. et al. Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses. J. Virol. 83, 6234-6246 (2009).
    • (2009) J. Virol. , vol.83 , pp. 6234-6246
    • Rudnicka, D.1
  • 24
    • 0022518143 scopus 로고
    • Role of the HTLVIII/LAV envelope in syncytium formation and cytopathicity
    • Sodroski, J., Goh, W. C., Rosen, C., Campbell, K. & Haseltine, W. A. Role of the HTLVIII/LAV envelope in syncytium formation and cytopathicity. Nature 322, 470-474 (1986).
    • (1986) Nature , vol.322 , pp. 470-474
    • Sodroski, J.1    Goh, W.C.2    Rosen, C.3    Campbell, K.4    Haseltine, W.A.5
  • 25
    • 39449098115 scopus 로고    scopus 로고
    • HIV-1 envelope protein binds to and signals through integrin a4b7, the gut mucosal homing receptor for peripheral T cells
    • Arthos, J. et al. HIV-1 envelope protein binds to and signals through integrin a4b7, the gut mucosal homing receptor for peripheral T cells. Nature Immunol. 9, 301-309 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 301-309
    • Arthos, J.1
  • 26
    • 0026095929 scopus 로고
    • Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity
    • Thali, M. et al. Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity. J. Virol. 65, 5007-5012 (1991).
    • (1991) J. Virol. , vol.65 , pp. 5007-5012
    • Thali, M.1
  • 27
    • 38849168755 scopus 로고    scopus 로고
    • Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission
    • Sowinski, S. et al. Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nature Cell Biol. 10, 211-219 (2008).
    • (2008) Nature Cell Biol. , vol.10 , pp. 211-219
    • Sowinski, S.1
  • 28
    • 33847366661 scopus 로고    scopus 로고
    • Retroviruses can establish filopodial bridges for efficient cell-tocell transmission
    • Sherer, N. M. et al. Retroviruses can establish filopodial bridges for efficient cell-tocell transmission. Nature Cell Biol. 9, 310-315 (2007).
    • (2007) Nature Cell Biol. , vol.9 , pp. 310-315
    • Sherer, N.M.1
  • 29
    • 62549151797 scopus 로고    scopus 로고
    • Evaluation of the lymphocyte trafficking drug FTY720 in SHIVSF162P3-infected rhesusmacaques
    • Kersh, E. N. et al. Evaluation of the lymphocyte trafficking drug FTY720 in SHIVSF162P3-infected rhesusmacaques. J. Antimicrob. Chemother. 63, 758-762 (2009).
    • (2009) J. Antimicrob. Chemother. , vol.63 , pp. 758-762
    • Kersh, E.N.1
  • 30
    • 67650410026 scopus 로고    scopus 로고
    • Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice
    • Brainard, D. M. et al. Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice. J. Virol. 83, 7305-7321 (2009).
    • (2009) J. Virol. , vol.83 , pp. 7305-7321
    • Brainard, D.M.1
  • 31
    • 0141521574 scopus 로고    scopus 로고
    • Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are wellconserved functions of human and simian immunodeficiency virus nef alleles
    • Schindler, M. et al. Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are wellconserved functions of human and simian immunodeficiency virus nef alleles. J. Virol. 77, 10548-10556 (2003).
    • (2003) J. Virol. , vol.77 , pp. 10548-10556
    • Schindler, M.1
  • 32
    • 0025783669 scopus 로고
    • Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
    • Hwang, S. S., Boyle, T. J., Lyerly, H. K.&Cullen, B. R. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 253, 71-74 (1991).
    • (1991) Science , vol.253 , pp. 71-74
    • Hwang, S.S.1    Boyle, T.J.2    Lyerly, H.K.3    Cullen, B.R.4
  • 33
    • 33750833078 scopus 로고    scopus 로고
    • Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer
    • Mostoslavsky, G., Fabian, A. J., Rooney, S., Alt, F. W. & Mulligan, R. C. Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proc. Natl Acad. Sci. USA 103, 16406-16411 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 16406-16411
    • Mostoslavsky, G.1    Fabian, A.J.2    Rooney, S.3    Alt, F.W.4    Mulligan, R.C.5
  • 34
    • 0033977791 scopus 로고    scopus 로고
    • Rapid phenotypic drug susceptibility assay for HIV-1 with a CCR5 expressing indicator cell line
    • Pirounaki, M., Heyden, N. A., Arens, M. & Ratner, L. Rapid phenotypic drug susceptibility assay for HIV-1 with a CCR5 expressing indicator cell line. J. Virol. Methods 85, 151-161 (2000).
    • (2000) J. Virol. Methods , vol.85 , pp. 151-161
    • Pirounaki, M.1    Heyden, N.A.2    Arens, M.3    Ratner, L.4
  • 35
    • 33344475250 scopus 로고    scopus 로고
    • Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes
    • Bondanza, A. et al. Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes. Blood 107, 1828-1836 (2006).
    • (2006) Blood , vol.107 , pp. 1828-1836
    • Bondanza, A.1
  • 36
    • 77954668607 scopus 로고    scopus 로고
    • Tetherin restricts productive HIV-1 cell-to-cell transmission
    • Casartelli, N. et al. Tetherin restricts productive HIV-1 cell-to-cell transmission. PLoS Pathog. 6, e1000955 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Casartelli, N.1
  • 37
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • Debes, G. F. et al. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nature Immunol. 6, 889-894 (2005).
    • (2005) Nature Immunol. , vol.6 , pp. 889-894
    • Debes, G.F.1
  • 38
    • 1542377328 scopus 로고    scopus 로고
    • B cell receptor signal strength determines B cell fate
    • Casola, S. et al. B cell receptor signal strength determines B cell fate. Nature Immunol. 5, 317-327 (2004).
    • (2004) Nature Immunol. , vol.5 , pp. 317-327
    • Casola, S.1
  • 39
    • 36248956701 scopus 로고    scopus 로고
    • Finding a way out: Lymphocyte egress from lymphoid organs
    • Schwab, S. R. & Cyster, J. G. Finding a way out: lymphocyte egress from lymphoid organs. Nature Immunol. 8, 1295-1301 (2007).
    • (2007) Nature Immunol. , vol.8 , pp. 1295-1301
    • Schwab, S.R.1    Cyster, J.G.2
  • 40
    • 80054735407 scopus 로고    scopus 로고
    • Multiphoton intravital microscopy to study lymphocyte motility in lymph nodes
    • Murooka, T. T. & Mempel, T. R. Multiphoton intravital microscopy to study lymphocyte motility in lymph nodes. Methods Mol. Biol. 757, 247-257 (2012).
    • (2012) Methods Mol. Biol. , vol.757 , pp. 247-257
    • Murooka, T.T.1    Mempel, T.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.