-
1
-
-
0028485232
-
HIV-1 Nef leads to inhibition or activation of T-cells depending on its intracellular-localization
-
Baur AS, Sawai ET, Dazin P, Fantl WJ, Chengmayer C, Peterlin BM. HIV-1 Nef leads to inhibition or activation of T-cells depending on its intracellular-localization. Immunity 1994; 1(5): 373-84.
-
(1994)
Immunity
, vol.1
, Issue.5
, pp. 373-384
-
-
Baur, A.S.1
Sawai, E.T.2
Dazin, P.3
Fantl, W.J.4
Chengmayer, C.5
Peterlin, B.M.6
-
2
-
-
0028224464
-
HIV-1 Nef activity in murine T-cells-CD4 modulation and positive enhancement
-
Rhee SS, Marsh JW. HIV-1 Nef activity in murine T-cells-CD4 modulation and positive enhancement. J Immunol 1994; 152(10): 5128-34.
-
(1994)
J Immunol
, vol.152
, Issue.10
, pp. 5128-5134
-
-
Rhee, S.S.1
Marsh, J.W.2
-
3
-
-
0027315870
-
CD4 down-regulation by Nef alleles Isolated from Human-Immunodeficiency-Virus Type 1-infected individuals
-
Mariani R, Skowronski J. CD4 down-regulation by Nef alleles Isolated from Human-Immunodeficiency-Virus Type 1-infected individuals. Proc Natl Acad Sci USA 1993; 90(12): 5549-53.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.12
, pp. 5549-5553
-
-
Mariani, R.1
Skowronski, J.2
-
4
-
-
0028302998
-
Optimal infectivity in-vitro of humanimmunodeficiency-virus type-1 requires an intact Nef gene
-
Chowers MY, Spina CA, Kwoh TJ, Fitch NJS, Richman DD, Guatelli JC. Optimal infectivity in-vitro of humanimmunodeficiency-virus type-1 requires an intact Nef gene. J Virol 1994; 68(5): 2906-14.
-
(1994)
J Virol
, vol.68
, Issue.5
, pp. 2906-2914
-
-
Chowers, M.Y.1
Spina, C.A.2
Kwoh, T.J.3
Fitch, N.J.S.4
Richman, D.D.5
Guatelli, J.C.6
-
5
-
-
0033529258
-
HIV-1 Nef increases T cell activation in a stimulus-dependent manner
-
Schrager JA, Marsh JW. HIV-1 Nef increases T cell activation in a stimulus-dependent manner. Proc Natl Acad Sci USA 1999; 96(14): 8167-72.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.14
, pp. 8167-8172
-
-
Schrager, J.A.1
Marsh, J.W.2
-
6
-
-
0034602776
-
The Nef protein of HIV-1 associates with rafts and primes T cells for activation
-
Wang JK, Kiyokawa E, Verdin E, Trono D. The Nef protein of HIV-1 associates with rafts and primes T cells for activation. Proc Natl Acad Sci USA 2000; 97(1): 394-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.1
, pp. 394-399
-
-
Wang, J.K.1
Kiyokawa, E.2
Verdin, E.3
Trono, D.4
-
7
-
-
4544288671
-
Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4(+) T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappa B, and AP-1 induction
-
Fortin JF, Barat C, Beausejour Y, Barbeau B, Tremblay MJ. Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4(+) T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappa B, and AP-1 induction. J Biol Chem 2004; 279(38): 39520-31.
-
(2004)
J Biol Chem
, vol.279
, Issue.38
, pp. 39520-39531
-
-
Fortin, J.F.1
Barat, C.2
Beausejour, Y.3
Barbeau, B.4
Tremblay, M.J.5
-
8
-
-
27144505682
-
Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement
-
Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA, Greene WC. Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. J Immunol 2005; 175(9): 6050-7.
-
(2005)
J Immunol
, vol.175
, Issue.9
, pp. 6050-6057
-
-
Fenard, D.1
Yonemoto, W.2
de Noronha, C.3
Cavrois, M.4
Williams, S.A.5
Greene, W.C.6
-
9
-
-
0034064726
-
P21-activated kinase 1 plays a critical role in cellular activation by Nef
-
Fackler OT, Lu XB, Frost JA, et al. P21-activated kinase 1 plays a critical role in cellular activation by Nef. Mol Cell Biol 2000; 20(7): 2619-27.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.7
, pp. 2619-2627
-
-
Fackler, O.T.1
Lu, X.B.2
Frost, J.A.3
-
10
-
-
0035123886
-
Activation of NFAT-dependent gene expression by Nef: Conservation among divergent Nef alleles, dependence on SH3 binding and membrane association, and cooperation with protein kinase C-theta
-
Manninen A, Huotari P, Hiipakka M, Renkema GH, Saksela K. Activation of NFAT-dependent gene expression by Nef: Conservation among divergent Nef alleles, dependence on SH3 binding and membrane association, and cooperation with protein kinase C-theta. J Virol 2001; 75(6): 3034-7.
-
(2001)
J Virol
, vol.75
, Issue.6
, pp. 3034-3037
-
-
Manninen, A.1
Huotari, P.2
Hiipakka, M.3
Renkema, G.H.4
Saksela, K.5
-
11
-
-
0034595806
-
Synergistic activation of NFAT by HIV-1 Nef and the Ras/MAPK pathway
-
Manninen A, Renkema GH, Saksela K. Synergistic activation of NFAT by HIV-1 Nef and the Ras/MAPK pathway. J Biol Chem 2000; 275(22): 16513-7.
-
(2000)
J Biol Chem
, vol.275
, Issue.22
, pp. 16513-16517
-
-
Manninen, A.1
Renkema, G.H.2
Saksela, K.3
-
12
-
-
79961104556
-
Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2
-
Olivieri KC, Mukerji J, Gabuzda D. Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2. Retrovirology 2011; 8: 64.
-
(2011)
Retrovirology
, vol.8
, pp. 64
-
-
Olivieri, K.C.1
Mukerji, J.2
Gabuzda, D.3
-
13
-
-
2642557101
-
HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion
-
Djordjevic JT, Schibeci SD, Stewart GJ, Williamson P. HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion. AIDS Res Hum Retroviruses 2004; 20(5): 547-55.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.5
, pp. 547-555
-
-
Djordjevic, J.T.1
Schibeci, S.D.2
Stewart, G.J.3
Williamson, P.4
-
14
-
-
0033827320
-
HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line
-
Schibeci SD, Clegg AO, Biti RA, Sagawa K, Stewart GJ, Williamson P. HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line. AIDS 2000; 14(12): 1701-7.
-
(2000)
AIDS
, vol.14
, Issue.12
, pp. 1701-1707
-
-
Schibeci, S.D.1
Clegg, A.O.2
Biti, R.A.3
Sagawa, K.4
Stewart, G.J.5
Williamson, P.6
-
15
-
-
0028006247
-
The human immunodeficiency virus-1 Nef gene-product-a positive factor for viral-infection and replication in primary lymphocytes and macrophages
-
Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB. The human immunodeficiency virus-1 Nef gene-product-a positive factor for viral-infection and replication in primary lymphocytes and macrophages. J Exp Med 1994; 179(1): 101-13.
-
(1994)
J Exp Med
, vol.179
, Issue.1
, pp. 101-113
-
-
Miller, M.D.1
Warmerdam, M.T.2
Gaston, I.3
Greene, W.C.4
Feinberg, M.B.5
-
16
-
-
0027952787
-
The importance of Nef in the induction of human-immunodeficiencyvirus type-1 replication from primary quiescent CD4 lymphocytes
-
Spina CA, Kwoh TJ, Chowers MY, Guatelli JC, Richman DD. The importance of Nef in the induction of human-immunodeficiencyvirus type-1 replication from primary quiescent CD4 lymphocytes. J Exp Med 1994; 179(1): 115-23.
-
(1994)
J Exp Med
, vol.179
, Issue.1
, pp. 115-123
-
-
Spina, C.A.1
Kwoh, T.J.2
Chowers, M.Y.3
Guatelli, J.C.4
Richman, D.D.5
-
17
-
-
0035943355
-
Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA
-
Wu YT, Marsh JW. Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA. Science 2001; 293(5534): 1503-6.
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1503-1506
-
-
Wu, Y.T.1
Marsh, J.W.2
-
18
-
-
0026717493
-
Natural HIV-1 Nef accelerates virus-replication in primary humanlymphocytes
-
Deronde A, Klaver B, Keulen W, Smit L, Goudsmit J. Natural HIV-1 Nef accelerates virus-replication in primary humanlymphocytes. Virology 1992; 188(1): 391-5.
-
(1992)
Virology
, vol.188
, Issue.1
, pp. 391-395
-
-
Deronde, A.1
Klaver, B.2
Keulen, W.3
Smit, L.4
Goudsmit, J.5
-
19
-
-
0036319189
-
Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism
-
Papkalla A, Munch J, Otto C, Kirchhoff F. Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism. J Virol 2002; 76(16): 8455-9.
-
(2002)
J Virol
, vol.76
, Issue.16
, pp. 8455-8459
-
-
Papkalla, A.1
Munch, J.2
Otto, C.3
Kirchhoff, F.4
-
20
-
-
0025773849
-
Cloning of a cellular factor, interleukin binding-factor, that binds to NFAT-like motifs in the human-immunodeficiency-virus long terminal repeat
-
Li C, Lai CF, Sigman DS, Gaynor RB. Cloning of a cellular factor, interleukin binding-factor, that binds to NFAT-like motifs in the human-immunodeficiency-virus long terminal repeat. Proc Natl Acad Sci USA 1991; 88(17): 7739-43.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, Issue.17
, pp. 7739-7743
-
-
Li, C.1
Lai, C.F.2
Sigman, D.S.3
Gaynor, R.B.4
-
21
-
-
0027275406
-
Human T-cell transcription factor GATA-3 stimulates HIV-1 expression
-
Yang ZY, Engel JD. Human T-cell transcription factor GATA-3 stimulates HIV-1 expression. Nucleic Acids Res 1993; 21(12): 2831-6.
-
(1993)
Nucleic Acids Res
, vol.21
, Issue.12
, pp. 2831-2836
-
-
Yang, Z.Y.1
Engel, J.D.2
-
22
-
-
0027209915
-
A cooperative interaction between NF-kappa-B and SP1 is required for HIV-1 enhancer activation
-
Perkins ND, Edwards NL, Duckett CS, Agranoff AB, Schmid RM, Nabel GJ. A cooperative interaction between NF-kappa-B and SP1 is required for HIV-1 enhancer activation. EMBO J 1993; 12(9): 3551-8.
-
(1993)
EMBO J
, vol.12
, Issue.9
, pp. 3551-3558
-
-
Perkins, N.D.1
Edwards, N.L.2
Duckett, C.S.3
Agranoff, A.B.4
Schmid, R.M.5
Nabel, G.J.6
-
23
-
-
0025974973
-
Cellular factors regulate transactivation of human-immunodeficiency-virus type-1
-
Barry PA, Prattlowe E, Unger RE, Luciw PA. Cellular factors regulate transactivation of human-immunodeficiency-virus type-1. J Virol 1991; 65(3): 1392-9.
-
(1991)
J Virol
, vol.65
, Issue.3
, pp. 1392-1399
-
-
Barry, P.A.1
Prattlowe, E.2
Unger, R.E.3
Luciw, P.A.4
-
24
-
-
0028290825
-
Control of RNA initiation and elongation at the HIV-1 promoter
-
Jones KA, Peterlin BM. Control of RNA initiation and elongation at the HIV-1 promoter. Annu Rev Biochem 1994; 63: 717-43.
-
(1994)
Annu Rev Biochem
, vol.63
, pp. 717-743
-
-
Jones, K.A.1
Peterlin, B.M.2
-
25
-
-
0025238945
-
HIV-1 replication is controlled at the level of T-cell activation and proviral integration
-
Stevenson M, Stanwick TL, Dempsey MP, Lamonica CA. HIV-1 replication is controlled at the level of T-cell activation and proviral integration. EMBO J 1990; 9(5): 1551-60.
-
(1990)
EMBO J
, vol.9
, Issue.5
, pp. 1551-1560
-
-
Stevenson, M.1
Stanwick, T.L.2
Dempsey, M.P.3
Lamonica, C.A.4
-
26
-
-
0024545370
-
Signaling through lymphocyte-T surface-proteins, TCR/CD3 and CD28, activates the HIV-1 long terminal repeat
-
Tongstarksen SE, Luciw PA, Peterlin BM. Signaling through lymphocyte-T surface-proteins, TCR/CD3 and CD28, activates the HIV-1 long terminal repeat. J Immunol 1989; 142(2): 702-7.
-
(1989)
J Immunol
, vol.142
, Issue.2
, pp. 702-707
-
-
Tongstarksen, S.E.1
Luciw, P.A.2
Peterlin, B.M.3
-
27
-
-
0027461317
-
Regulation of lymphocyte function by protein-phosphorylation
-
Perlmutter RM, Levin SD, Appleby MW, Anderson SJ, Alberolaila J. Regulation of lymphocyte function by protein-phosphorylation. Annu Rev Immunol 1993; 11: 451-99.
-
(1993)
Annu Rev Immunol
, vol.11
, pp. 451-499
-
-
Perlmutter, R.M.1
Levin, S.D.2
Appleby, M.W.3
Anderson, S.J.4
Alberolaila, J.5
-
28
-
-
0028014460
-
Signal-transduction by lymphocyte antigen receptors
-
Weiss A, Littman DR. Signal-transduction by lymphocyte antigen receptors. Cell 1994; 76(2): 263-74.
-
(1994)
Cell
, vol.76
, Issue.2
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
29
-
-
0037155156
-
HIV Nef increases T cell Erk MAP kinase activity
-
Schrager JA, Minassian VD, Marsh JW. HIV Nef increases T cell Erk MAP kinase activity. J Biol Chem 2002; 277(8): 6137-42.
-
(2002)
J Biol Chem
, vol.277
, Issue.8
, pp. 6137-6142
-
-
Schrager, J.A.1
Minassian, V.D.2
Marsh, J.W.3
-
30
-
-
10944244131
-
HIV-1 Nef promotes survival of TF-1 macrophages by inducing Bcl-X-L expression in an extracellular signal-regulated kinase-dependent manner
-
Choi HJ, Smithgall TE. HIV-1 Nef promotes survival of TF-1 macrophages by inducing Bcl-X-L expression in an extracellular signal-regulated kinase-dependent manner. J Biol Chem 2004; 279(49): 51688-96.
-
(2004)
J Biol Chem
, vol.279
, Issue.49
, pp. 51688-51696
-
-
Choi, H.J.1
Smithgall, T.E.2
-
31
-
-
58849132949
-
Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of Erk1/2 but not NF kappa B
-
Witte V, Laffert B, Gintschel P, et al. Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of Erk1/2 but not NF kappa B. J Immunol 2008; 181(12): 8425-32.
-
(2008)
J Immunol
, vol.181
, Issue.12
, pp. 8425-8432
-
-
Witte, V.1
Laffert, B.2
Gintschel, P.3
-
32
-
-
84856077084
-
HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling
-
Pan XY, Rudolph JM, Abraham L, et al. HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling. Blood 2012; 119(3): 786-97.
-
(2012)
Blood
, vol.119
, Issue.3
, pp. 786-797
-
-
Pan, X.Y.1
Rudolph, J.M.2
Abraham, L.3
-
33
-
-
78751701271
-
The HIV-1 Nef protein has a dual role in T cell receptor signaling in infected CD4(+) T lymphocytes
-
Neri F, Giolo G, Potesta M, Petrini S, Doria M. The HIV-1 Nef protein has a dual role in T cell receptor signaling in infected CD4(+) T lymphocytes. Virology 2011; 410(2): 316-26.
-
(2011)
Virology
, vol.410
, Issue.2
, pp. 316-326
-
-
Neri, F.1
Giolo, G.2
Potesta, M.3
Petrini, S.4
Doria, M.5
-
34
-
-
0032955536
-
Direct evidence that ERK regulates the production/secretion of interleukin-2 in PHA/PMAstimulated T lymphocytes
-
Li YQ, Hii CST, Der CJ, Ferrante A. Direct evidence that ERK regulates the production/secretion of interleukin-2 in PHA/PMAstimulated T lymphocytes. Immunology 1999; 96(4): 524-8.
-
(1999)
Immunology
, vol.96
, Issue.4
, pp. 524-528
-
-
Li, Y.Q.1
Hii, C.S.T.2
Der, C.J.3
Ferrante, A.4
-
35
-
-
0029777285
-
Multiple p21ras effector pathways regulate nuclear factor of activated T cells
-
Genot E, Cleverley S, Henning S, Cantrell D. Multiple p21ras effector pathways regulate nuclear factor of activated T cells. EMBO J 1996; 15(15): 3923-33.
-
(1996)
EMBO J
, vol.15
, Issue.15
, pp. 3923-3933
-
-
Genot, E.1
Cleverley, S.2
Henning, S.3
Cantrell, D.4
-
36
-
-
0029043582
-
How MAP kinases are regulated
-
Cobb MH, Goldsmith EJ. How MAP kinases are regulated. J Biol Chem 1995; 270(25): 14843-6.
-
(1995)
J Biol Chem
, vol.270
, Issue.25
, pp. 14843-14846
-
-
Cobb, M.H.1
Goldsmith, E.J.2
-
37
-
-
24944490193
-
The ERK cascade-A prototype of MAPK signaling
-
Rubinfeld H, Seger R. The ERK cascade-A prototype of MAPK signaling. Mol Biotechnol 2005; 31(2): 151-74.
-
(2005)
Mol Biotechnol
, vol.31
, Issue.2
, pp. 151-174
-
-
Rubinfeld, H.1
Seger, R.2
-
38
-
-
0032974805
-
Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway
-
Yang XY, Gabuzda D. Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway. J Virol 1999; 73(4): 3460-6.
-
(1999)
J Virol
, vol.73
, Issue.4
, pp. 3460-3466
-
-
Yang, X.Y.1
Gabuzda, D.2
-
39
-
-
0028609382
-
Integrinmediated signal-transduction linked to ras pathway by grb2 binding to focal adhesion kinase
-
Schlaepfer DD, Hanks SK, Hunter T, Vandergeer P. Integrinmediated signal-transduction linked to ras pathway by grb2 binding to focal adhesion kinase. Nature 1994; 372(6508): 786-91.
-
(1994)
Nature
, vol.372
, Issue.6508
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Vandergeer, P.4
-
40
-
-
0032538798
-
Integrins induce activation of EGF receptor: Role in MAP kinase induction and adhesiondependent cell survival
-
Moro L, Venturino M, Bozzo C, et al. Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesiondependent cell survival. EMBO J 1998; 17(22): 6622-32.
-
(1998)
EMBO J
, vol.17
, Issue.22
, pp. 6622-6632
-
-
Moro, L.1
Venturino, M.2
Bozzo, C.3
-
41
-
-
0030830220
-
Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins
-
Frost JA, Steen H, Shapiro P, et al. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J 1997; 16(21): 6426-38.
-
(1997)
EMBO J
, vol.16
, Issue.21
, pp. 6426-6438
-
-
Frost, J.A.1
Steen, H.2
Shapiro, P.3
-
42
-
-
0042672912
-
PAKI phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
-
Slack-Davis JK, Eblen ST, Zecevic M, et al. PAKI phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation. J Cell Biol 2003; 162(2): 281-91.
-
(2003)
J Cell Biol
, vol.162
, Issue.2
, pp. 281-291
-
-
Slack-Davis, J.K.1
Eblen, S.T.2
Zecevic, M.3
-
43
-
-
0036333485
-
Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEKI-ERK complexes
-
Eblen ST, Slack JK, Weber MJ, Catling AD. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEKI-ERK complexes. Mol Cell Biol 2002; 22(17): 6023-33.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.17
, pp. 6023-6033
-
-
Eblen, S.T.1
Slack, J.K.2
Weber, M.J.3
Catling, A.D.4
-
44
-
-
0037192630
-
PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway
-
Coles LC, Shaw PE. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. Oncogene 2002; 21(14): 2236-44.
-
(2002)
Oncogene
, vol.21
, Issue.14
, pp. 2236-2244
-
-
Coles, L.C.1
Shaw, P.E.2
-
45
-
-
27744521323
-
Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors
-
Beeser A, Jaffer ZM, Hofmann C, Chernoff J. Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors. J Biol Chem 2005; 280(44): 36609-15.
-
(2005)
J Biol Chem
, vol.280
, Issue.44
, pp. 36609-36615
-
-
Beeser, A.1
Jaffer, Z.M.2
Hofmann, C.3
Chernoff, J.4
-
46
-
-
0027958148
-
Human-Immunodeficiency-Virus Type-1 Nef associates with a cellular serine kinase in T-lymphocytes
-
Sawai ET, Baur A, Struble H, Peterlin BM, Levy JA, Chengmayer C. Human-Immunodeficiency-Virus Type-1 Nef associates with a cellular serine kinase in T-lymphocytes. Proc Natl Acad Sci USA 1994; 91(4): 1539-43.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.4
, pp. 1539-1543
-
-
Sawai, E.T.1
Baur, A.2
Struble, H.3
Peterlin, B.M.4
Levy, J.A.5
Chengmayer, C.6
-
47
-
-
0029793714
-
Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family
-
Nunn MF, Marsh JW. Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family. J Virol 1996; 70(9): 6157-61.
-
(1996)
J Virol
, vol.70
, Issue.9
, pp. 6157-6161
-
-
Nunn, M.F.1
Marsh, J.W.2
-
48
-
-
0030947406
-
The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix
-
Swingler S, Gallay P, Camaur D, Song JP, Abo A, Trono D. The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix. J Virol 1997; 71(6): 4372-7.
-
(1997)
J Virol
, vol.71
, Issue.6
, pp. 4372-4377
-
-
Swingler, S.1
Gallay, P.2
Camaur, D.3
Song, J.P.4
Abo, A.5
Trono, D.6
-
49
-
-
0035173735
-
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals
-
Wolf D, Witte V, Laffert B, et al. HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals. Nat Med 2001; 7(11): 1217-24.
-
(2001)
Nat Med
, vol.7
, Issue.11
, pp. 1217-1224
-
-
Wolf, D.1
Witte, V.2
Laffert, B.3
-
50
-
-
27744540710
-
Activation of p21-activated kinase 2 by human immunodeficiency virus type 1 Nef induces merlin phosphorylation
-
Wei BL, Arora VK, Raney A, et al. Activation of p21-activated kinase 2 by human immunodeficiency virus type 1 Nef induces merlin phosphorylation. J Virol 2005; 79(23): 14976-80.
-
(2005)
J Virol
, vol.79
, Issue.23
, pp. 14976-14980
-
-
Wei, B.L.1
Arora, V.K.2
Raney, A.3
-
51
-
-
84874238349
-
HIV Nef, Paxillin, and Pak1/2 Regulate Activation and Secretion of TACE/ADAM10 Proteases
-
Lee J-H, Wittki S, Brau T, et al. HIV Nef, Paxillin, and Pak1/2 Regulate Activation and Secretion of TACE/ADAM10 Proteases. Mol Cell 2013; 49(4): 668-79.
-
(2013)
Mol Cell
, vol.49
, Issue.4
, pp. 668-679
-
-
Lee, J.-H.1
Wittki, S.2
Brau, T.3
-
52
-
-
68549123450
-
HIV-1 Nef interferes with host cell motility by deregulation of Cofilin
-
Stolp B, Reichman-Fried M, Abraham L, et al. HIV-1 Nef interferes with host cell motility by deregulation of Cofilin. Cell Host Microbe 2009; 6(2): 174-86.
-
(2009)
Cell Host Microbe
, vol.6
, Issue.2
, pp. 174-186
-
-
Stolp, B.1
Reichman-Fried, M.2
Abraham, L.3
-
53
-
-
36349022028
-
Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in Ex vivo-infected human lymphoid tissue
-
Schindler M, Rajan D, Specht A, et al. Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in Ex vivo-infected human lymphoid tissue. J Virol 2007; 81(23): 13005-14.
-
(2007)
J Virol
, vol.81
, Issue.23
, pp. 13005-13014
-
-
Schindler, M.1
Rajan, D.2
Specht, A.3
-
54
-
-
0034682812
-
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
-
Tan Y, Demeter MR, Ruan H, Comb MJ. BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival. J Biol Chem 2000; 275(33): 25865-9.
-
(2000)
J Biol Chem
, vol.275
, Issue.33
, pp. 25865-25869
-
-
Tan, Y.1
Demeter, M.R.2
Ruan, H.3
Comb, M.J.4
-
55
-
-
0030755466
-
Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney
-
Yin TG, Sandhu G, Wolfgang CD, et al. Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney. J Biol Chem 1997; 272(32): 19943-50.
-
(1997)
J Biol Chem
, vol.272
, Issue.32
, pp. 19943-19950
-
-
Yin, T.G.1
Sandhu, G.2
Wolfgang, C.D.3
-
56
-
-
0033546439
-
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
-
Rena G, Guo SD, Cichy SC, Unterman TG, Cohen P. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 1999; 274(24): 17179-83.
-
(1999)
J Biol Chem
, vol.274
, Issue.24
, pp. 17179-17183
-
-
Rena, G.1
Guo, S.D.2
Cichy, S.C.3
Unterman, T.G.4
Cohen, P.5
-
57
-
-
0038013782
-
Ataxia-telangiectasiamutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation
-
Gatei M, Sloper K, Sorensen C, et al. Ataxia-telangiectasiamutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation. J Biol Chem 2003; 278(17): 14806-11.
-
(2003)
J Biol Chem
, vol.278
, Issue.17
, pp. 14806-14811
-
-
Gatei, M.1
Sloper, K.2
Sorensen, C.3
-
58
-
-
3242683662
-
Single cell profiling of potentiated phospho-protein networks in cancer cells
-
Irish JM, Hovland R, Krutzik PO, et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 2004; 118(2): 217-28.
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 217-228
-
-
Irish, J.M.1
Hovland, R.2
Krutzik, P.O.3
-
59
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell-surface CD4 by Nef
-
Garcia JV, Miller AD. Serine phosphorylation-independent downregulation of cell-surface CD4 by Nef. Nature 1991; 350(6318): 508-11.
-
(1991)
Nature
, vol.350
, Issue.6318
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
60
-
-
0035980010
-
HIV Nef-mediated cellular phenotypes are differentially expressed as a function of intracellular NEF concentrations
-
Liu XX, Schrager JA, Lange GD, Marsh JW. HIV Nef-mediated cellular phenotypes are differentially expressed as a function of intracellular NEF concentrations. J Biol Chem 2001; 276(35): 32763-70.
-
(2001)
J Biol Chem
, vol.276
, Issue.35
, pp. 32763-32770
-
-
Liu, X.X.1
Schrager, J.A.2
Lange, G.D.3
Marsh, J.W.4
-
61
-
-
0022546877
-
AIDS retrovirus induced cytopathology-giant-cell formation and involvement of CD4 antigen
-
Lifson JD, Reyes GR, McGrath MS, Stein BS, Engleman EG. AIDS retrovirus induced cytopathology-giant-cell formation and involvement of CD4 antigen. Science 1986; 232(4754): 1123-7.
-
(1986)
Science
, vol.232
, Issue.4754
, pp. 1123-1127
-
-
Lifson, J.D.1
Reyes, G.R.2
McGrath, M.S.3
Stein, B.S.4
Engleman, E.G.5
-
62
-
-
0021707158
-
T4 positive human neoplastic cell-lines susceptible to and permissive for HTLV-III
-
Popovic M, Readconnole E, Gallo RC. T4 positive human neoplastic cell-lines susceptible to and permissive for HTLV-III. Lancet 1984; 2(8417): 1472-3.
-
(1984)
Lancet
, vol.2
, Issue.8417
, pp. 1472-1473
-
-
Popovic, M.1
Readconnole, E.2
Gallo, R.C.3
-
63
-
-
0028180868
-
Nef induces CD4 endocytosis-requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
-
Aiken C, Konner J, Landau NR, Lenburg ME, Trono D. Nef induces CD4 endocytosis-requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 1994; 76(5): 853-64.
-
(1994)
Cell
, vol.76
, Issue.5
, pp. 853-864
-
-
Aiken, C.1
Konner, J.2
Landau, N.R.3
Lenburg, M.E.4
Trono, D.5
-
64
-
-
0028200761
-
Human-immunodeficiency-virus type-1 Nefinduced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4
-
Rhee SS, Marsh JW. Human-immunodeficiency-virus type-1 Nefinduced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. J Virol 1994; 68(8): 5156-63.
-
(1994)
J Virol
, vol.68
, Issue.8
, pp. 5156-5163
-
-
Rhee, S.S.1
Marsh, J.W.2
-
65
-
-
0036635758
-
The K252a derivatives, inhibitors for the PAK/MLK kinase family, selectively block the growth of RAS transformants
-
Nheu TV, He H, Hirokawa Y, et al. The K252a derivatives, inhibitors for the PAK/MLK kinase family, selectively block the growth of RAS transformants. Cancer J 2002; 8(4): 328-36.
-
(2002)
Cancer J
, vol.8
, Issue.4
, pp. 328-336
-
-
Nheu, T.V.1
He, H.2
Hirokawa, Y.3
-
66
-
-
41949100602
-
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase
-
Deacon SW, Beeser A, Fukui JA, et al. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol 2008; 15(4): 322-31.
-
(2008)
Chem Biol
, vol.15
, Issue.4
, pp. 322-331
-
-
Deacon, S.W.1
Beeser, A.2
Fukui, J.A.3
-
67
-
-
70349484472
-
An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently
-
Viaud J, Peterson JR. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther 2009; 8(9): 2559-65.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.9
, pp. 2559-2565
-
-
Viaud, J.1
Peterson, J.R.2
-
68
-
-
0028078824
-
A brain serine threonine protein-kinase activated by CDC42 and Rac1
-
Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L. A brain serine threonine protein-kinase activated by CDC42 and Rac1. Nature 1994; 367(6458): 40-6.
-
(1994)
Nature
, vol.367
, Issue.6458
, pp. 40-46
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Zhao, Z.S.4
Lim, L.5
-
69
-
-
0035907296
-
The mechanism of PAK activation-Autophosphorylation events in both regulatory and kinase domains control activity
-
Chong C, Tan L, Lim L, Manser E. The mechanism of PAK activation-Autophosphorylation events in both regulatory and kinase domains control activity. J Biol Chem 2001; 276(20): 17347-53.
-
(2001)
J Biol Chem
, vol.276
, Issue.20
, pp. 17347-17353
-
-
Chong, C.1
Tan, L.2
Lim, L.3
Manser, E.4
-
70
-
-
0032478605
-
A GTPase-independent mechanism of PAK activation: Regulation by sphingosine and other biologically active lipids
-
King CC, Bokoch GM, Reilly AM, et al. A GTPase-independent mechanism of PAK activation: Regulation by sphingosine and other biologically active lipids. J Leukoc Biol 1998: 273(14): 8137-44.
-
(1998)
J Leukoc Biol
, vol.273
, Issue.14
, pp. 8137-8144
-
-
King, C.C.1
Bokoch, G.M.2
Reilly, A.M.3
-
71
-
-
1942518365
-
GITI activates p21-activated kinase through a mechanism independent of p21 binding
-
Loo TH, Ng YW, Lim L, Manser E. GITI activates p21-activated kinase through a mechanism independent of p21 binding. Mol Cell Biol 2004; 24(9): 3849-59.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.9
, pp. 3849-3859
-
-
Loo, T.H.1
Ng, Y.W.2
Lim, L.3
Manser, E.4
-
72
-
-
37249019970
-
Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of rac family small GTPases
-
Shutes A, Onesto C, Picard V, Leblond B, Schweighoffer F, Der CJ. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of rac family small GTPases. J Biol Chem 2007; 282(49): 35666-78.
-
(2007)
J Biol Chem
, vol.282
, Issue.49
, pp. 35666-35678
-
-
Shutes, A.1
Onesto, C.2
Picard, V.3
Leblond, B.4
Schweighoffer, F.5
Der, C.J.6
-
73
-
-
2442664118
-
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
-
Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci USA 2004; 101(20): 7618-23.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.20
, pp. 7618-7623
-
-
Gao, Y.1
Dickerson, J.B.2
Guo, F.3
Zheng, J.4
Zheng, Y.5
-
74
-
-
19344363916
-
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate Rac and inhibit lymphocyte chemotaxis
-
Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J. HIV-1 Nef binds the DOCK2-ELMO1 complex to activate Rac and inhibit lymphocyte chemotaxis. PLoS Biol 2004; 2(1): 65-76.
-
(2004)
PLoS Biol
, vol.2
, Issue.1
, pp. 65-76
-
-
Janardhan, A.1
Swigut, T.2
Hill, B.3
Myers, M.P.4
Skowronski, J.5
-
75
-
-
0032566903
-
SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
-
Manninen A, Hiipakka M, Vihinen M, Lu W, Mayer BJ, Saksela K. SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase. Virology 1998; 250(2): 273-82.
-
(1998)
Virology
, vol.250
, Issue.2
, pp. 273-282
-
-
Manninen, A.1
Hiipakka, M.2
Vihinen, M.3
Lu, W.4
Mayer, B.J.5
Saksela, K.6
-
76
-
-
0030273317
-
HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis
-
Wiskerchen M, Chengmayer C. HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis. Virology 1996; 224(1): 292-301.
-
(1996)
Virology
, vol.224
, Issue.1
, pp. 292-301
-
-
Wiskerchen, M.1
Chengmayer, C.2
-
77
-
-
33644778761
-
A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2
-
Agopian K, Wei BL, Garcia JV, Gabuzda D. A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. J Virol 2006; 80(6): 3050-61.
-
(2006)
J Virol
, vol.80
, Issue.6
, pp. 3050-3061
-
-
Agopian, K.1
Wei, B.L.2
Garcia, J.V.3
Gabuzda, D.4
-
78
-
-
31144476786
-
Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef
-
O'Neill E, Kuo LS, Krisko JF, Tomchick DR, Garcia JV, Foster JL. Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef. J Virol 2006; 80(3): 1311-20.
-
(2006)
J Virol
, vol.80
, Issue.3
, pp. 1311-1320
-
-
O'Neill, E.1
Kuo, L.S.2
Krisko, J.F.3
Tomchick, D.R.4
Garcia, J.V.5
Foster, J.L.6
-
79
-
-
0031039979
-
Separable functions of nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
-
Iafrate AJ, Bronson S, Skowronski J. Separable functions of nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J 1997; 16(4): 673-84.
-
(1997)
EMBO J
, vol.16
, Issue.4
, pp. 673-684
-
-
Iafrate, A.J.1
Bronson, S.2
Skowronski, J.3
-
80
-
-
0028878783
-
Proline-rich (pxxp) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of nef(+) viruses but not for down-regulation of CD4
-
Saksela K, Cheng GH, Baltimore D. Proline-rich (pxxp) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of nef(+) viruses but not for down-regulation of CD4. EMBO J 1995; 14(3): 484-91.
-
(1995)
EMBO J
, vol.14
, Issue.3
, pp. 484-491
-
-
Saksela, K.1
Cheng, G.H.2
Baltimore, D.3
-
81
-
-
0032525137
-
The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
-
Greenberg ME, Iafrate AJ, Skowronski J. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J 1998; 17(10): 2777-89.
-
(1998)
EMBO J
, vol.17
, Issue.10
, pp. 2777-2789
-
-
Greenberg, M.E.1
Iafrate, A.J.2
Skowronski, J.3
-
82
-
-
0033568473
-
Analysis of the SH3-Binding region of HIV-1 Nef: Partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket
-
Craig HM, Pandori MW, Riggs NL, Richman DD, Guatelli JC. Analysis of the SH3-Binding region of HIV-1 Nef: Partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket. Virology 1999; 262(1): 55-63.
-
(1999)
Virology
, vol.262
, Issue.1
, pp. 55-63
-
-
Craig, H.M.1
Pandori, M.W.2
Riggs, N.L.3
Richman, D.D.4
Guatelli, J.C.5
-
83
-
-
0031036626
-
Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
-
Manser E, Huang HY, Loo TH, et al. Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes. Mol Cell Biol 1997; 17(3): 1129-43.
-
(1997)
Mol Cell Biol
, vol.17
, Issue.3
, pp. 1129-1143
-
-
Manser, E.1
Huang, H.Y.2
Loo, T.H.3
-
84
-
-
0032582669
-
Cleavage and activation of pal-activated protein kinase gamma-PAK by CPP32 (Caspase 3)-Effects of autophosphorylation on activity
-
Walter BN, Huang ZD, Jakobi R, et al. Cleavage and activation of pal-activated protein kinase gamma-PAK by CPP32 (Caspase 3)-Effects of autophosphorylation on activity. J Biol Chem 1998; 273(44): 28733-9.
-
(1998)
J Biol Chem
, vol.273
, Issue.44
, pp. 28733-28739
-
-
Walter, B.N.1
Huang, Z.D.2
Jakobi, R.3
-
85
-
-
0034731505
-
P21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositidedependent kinase-1 (PDK1)
-
King CC, Gardiner EMM, Zenke FT, et al. P21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositidedependent kinase-1 (PDK1). J Biol Chem 2000; 275(52): 41201-9.
-
(2000)
J Biol Chem
, vol.275
, Issue.52
, pp. 41201-41209
-
-
King, C.C.1
Gardiner, E.M.M.2
Zenke, F.T.3
-
86
-
-
0033583287
-
Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation
-
Gatti A, Huang ZD, Tuazon PT, Traugh JA. Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation. J Biol Chem 1999; 274(12): 8022-8.
-
(1999)
J Biol Chem
, vol.274
, Issue.12
, pp. 8022-8028
-
-
Gatti, A.1
Huang, Z.D.2
Tuazon, P.T.3
Traugh, J.A.4
-
87
-
-
0029134875
-
Activation of an S6/H4 kinase (Pak-65) from human placenta by intramolecular and intermolecular autophosphorylation
-
Benner GE, Dennis PB, Masaracchia RA. Activation of an S6/H4 kinase (Pak-65) from human placenta by intramolecular and intermolecular autophosphorylation. J Biol Chem 1995; 270(36): 21121-8.
-
(1995)
J Biol Chem
, vol.270
, Issue.36
, pp. 21121-21128
-
-
Benner, G.E.1
Dennis, P.B.2
Masaracchia, R.A.3
-
88
-
-
2942555187
-
A novel role for p21-activated protein kinase 2 in T cell activation
-
Chu PC, Wu J, Liao XC, et al. A novel role for p21-activated protein kinase 2 in T cell activation. J Immunol 2004; 172(12): 7324-34.
-
(2004)
J Immunol
, vol.172
, Issue.12
, pp. 7324-7334
-
-
Chu, P.C.1
Wu, J.2
Liao, X.C.3
-
89
-
-
0035873136
-
Phosphorylation of the activation loop of gamma p21-activated kinase (gamma-Pak) and related kinases (MSTs) in normal and stressed neutrophils
-
Lian JP, Toker A, Badwey JA. Phosphorylation of the activation loop of gamma p21-activated kinase (gamma-Pak) and related kinases (MSTs) in normal and stressed neutrophils. J Immunol 2001; 166(10): 6349-57.
-
(2001)
J Immunol
, vol.166
, Issue.10
, pp. 6349-6357
-
-
Lian, J.P.1
Toker, A.2
Badwey, J.A.3
-
90
-
-
0037015055
-
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
-
Riley JL, Mao M, Kobayashi S, et al. Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors. Proc Natl Acad Sci USA 2002; 99(18): 11790-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.18
, pp. 11790-11795
-
-
Riley, J.L.1
Mao, M.2
Kobayashi, S.3
-
91
-
-
33845350068
-
AILIM/ICOSmediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade
-
Nukada Y, Okamoto N, Konakahara S, et al. AILIM/ICOSmediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade. Int Immunol 2006; 18(12): 1815-24.
-
(2006)
Int Immunol
, vol.18
, Issue.12
, pp. 1815-1824
-
-
Nukada, Y.1
Okamoto, N.2
Konakahara, S.3
-
92
-
-
44349127316
-
alpha PIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling
-
Missy K, Hu B, Schilling K, et al. alpha PIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling. Mol Cell Biol 2008; 28(11): 3776-89.
-
(2008)
Mol Cell Biol
, vol.28
, Issue.11
, pp. 3776-3789
-
-
Missy, K.1
Hu, B.2
Schilling, K.3
-
93
-
-
0141920605
-
P21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases
-
Zhan Q, Ge QY, Ohira T, Van Dyke T, Badwey JA. P21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases. J Immunol 2003; 171(7): 3785-93.
-
(2003)
J Immunol
, vol.171
, Issue.7
, pp. 3785-3793
-
-
Zhan, Q.1
Ge, Q.Y.2
Ohira, T.3
van Dyke, T.4
Badwey, J.A.5
-
94
-
-
0034469146
-
Lentivirus Nef specifically activates Pak2
-
Arora VK, Molina RP, Foster JL, et al. Lentivirus Nef specifically activates Pak2. J Virol 2000; 74(23): 11081-7.
-
(2000)
J Virol
, vol.74
, Issue.23
, pp. 11081-11087
-
-
Arora, V.K.1
Molina, R.P.2
Foster, J.L.3
-
95
-
-
0033518291
-
Identification of the Nef-associated kinase as p21-activated kinase 2
-
Renkema GH, Manninen A, Mann DA, Harris M, Saksela K. Identification of the Nef-associated kinase as p21-activated kinase 2. Curr Biol 1999; 9(23): 1407-10.
-
(1999)
Curr Biol
, vol.9
, Issue.23
, pp. 1407-1410
-
-
Renkema, G.H.1
Manninen, A.2
Mann, D.A.3
Harris, M.4
Saksela, K.5
-
96
-
-
26444552330
-
Reconstitution and molecular analysis of an active human immunodeficiency virus type 1 Nef/p21-activated kinase 2 complex
-
Raney A, Kuo LS, Baugh LL, Foster JL, Garcia JV. Reconstitution and molecular analysis of an active human immunodeficiency virus type 1 Nef/p21-activated kinase 2 complex. J Virol 2005; 79(20): 12732-41.
-
(2005)
J Virol
, vol.79
, Issue.20
, pp. 12732-12741
-
-
Raney, A.1
Kuo, L.S.2
Baugh, L.L.3
Foster, J.L.4
Garcia, J.V.5
-
97
-
-
12144291075
-
Human immunodeficiency virus type 1 nef activates p21-activated kinase via recruitment into lipid rafts
-
Krautkramer E, Giese SI, Gasteier JE, Muranyi W, Fackler OT. Human immunodeficiency virus type 1 nef activates p21-activated kinase via recruitment into lipid rafts. J Virol 2004; 78(8): 4085-97.
-
(2004)
J Virol
, vol.78
, Issue.8
, pp. 4085-4097
-
-
Krautkramer, E.1
Giese, S.I.2
Gasteier, J.E.3
Muranyi, W.4
Fackler, O.T.5
-
98
-
-
8644224930
-
Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts
-
Pulkkinen K, Renkema GH, Kirchhoff F, Saksela K. Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts. J Virol 2004; 78(23): 12773-80.
-
(2004)
J Virol
, vol.78
, Issue.23
, pp. 12773-12780
-
-
Pulkkinen, K.1
Renkema, G.H.2
Kirchhoff, F.3
Saksela, K.4
-
99
-
-
0029064101
-
A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinaseactivity
-
Sawai ET, Baur AS, Peterlin BM, Levy JA, Chengmayer C. A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinaseactivity. J Biol Chem 1995; 270(25): 15307-14.
-
(1995)
J Biol Chem
, vol.270
, Issue.25
, pp. 15307-15314
-
-
Sawai, E.T.1
Baur, A.S.2
Peterlin, B.M.3
Levy, J.A.4
Chengmayer, C.5
-
100
-
-
40149097137
-
Human immunodeficiency virus type 1 nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity
-
Rauch S, Pulkkinen K, Saksela K, Fackler OT. Human immunodeficiency virus type 1 nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity. J Virol 2008; 82(6): 2918-29.
-
(2008)
J Virol
, vol.82
, Issue.6
, pp. 2918-2929
-
-
Rauch, S.1
Pulkkinen, K.2
Saksela, K.3
Fackler, O.T.4
-
101
-
-
0031080595
-
Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
-
Lu WG, Katz S, Gupta R, Mayer BJ. Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. Curr Biol 1997; 7(2): 85-94.
-
(1997)
Curr Biol
, vol.7
, Issue.2
, pp. 85-94
-
-
Lu, W.G.1
Katz, S.2
Gupta, R.3
Mayer, B.J.4
-
102
-
-
69949177832
-
Dissecting Activation of the PAK1 Kinase at Protrusions in Living Cells
-
Parrini MC, Camonis J, Matsuda M, de Gunzburg J. Dissecting Activation of the PAK1 Kinase at Protrusions in Living Cells. J Biol Chem 2009; 284(36): 24133-43.
-
(2009)
J Biol Chem
, vol.284
, Issue.36
, pp. 24133-24143
-
-
Parrini, M.C.1
Camonis, J.2
Matsuda, M.3
de Gunzburg, J.4
-
103
-
-
10744228109
-
HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane
-
Witte V, Laffert B, Rosorius O, et al. HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane. Mol Cell 2004; 13(2): 179-90.
-
(2004)
Mol Cell
, vol.13
, Issue.2
, pp. 179-190
-
-
Witte, V.1
Laffert, B.2
Rosorius, O.3
|