Neuroinflammation in healthy aging: A PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [18F]-FEPPA

NeuroImage

Volumn 84, Issue , 2014, Pages 868-875

  Suridjan, I ^a   Rusjan, P M ^a   Voineskos, A N ^a,b   Selvanathan, T ^a   Setiawan, E ^a   Strafella, A P ^a,c   Wilson, A A ^a,b   Meyer, J H ^a,b   Houle, S ^a   Mizrahi, R ^a,b  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Healthy aging; Microglia activation; Neuroinflammation; PET imaging; TSPO

Indexed keywords

FEPPA F 18; GENOMIC DNA; MITOCHONDRIAL PROTEIN; RADIOLIGAND; TSPO PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; AGING; ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG DISTRIBUTION; FEMALE; GENE; GENOTYPE; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; TEMPORAL CORTEX; TSPO GENE; VOLUNTEER;

HEALTHY AGING; MICROGLIA ACTIVATION; NEUROINFLAMMATION; PET IMAGING; TSPO; [(18)F]-FEPPA;

AGING; ANILIDES; BRAIN; FEMALE; FLUORINE RADIOISOTOPES; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; INFLAMMATION; MALE; MICROGLIA; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RADIOPHARMACEUTICALS; RECEPTORS, GABA;

EID: 84885710671     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2013.09.021     Document Type: Article

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