-
1
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
Naldini L, Blomer U, Gage FH, Trono D, Verma IM, (1996) Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A 93: 11382-11388.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
Trono, D.4
Verma, I.M.5
-
2
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, et al. (1996) In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272: 263-267.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
-
3
-
-
33750031102
-
Vector-based RNAi approaches for stable, inducible and genome-wide screens
-
Fewell GD, Schmitt K, (2006) Vector-based RNAi approaches for stable, inducible and genome-wide screens. Drug Discov Today 11: 975-982.
-
(2006)
Drug Discov Today
, vol.11
, pp. 975-982
-
-
Fewell, G.D.1
Schmitt, K.2
-
4
-
-
84860133437
-
Lentiviral vectors: basic to translational
-
Sakuma T, Barry MA, Ikeda Y, (2012) Lentiviral vectors: basic to translational. Biochem J 443: 603-618.
-
(2012)
Biochem J
, vol.443
, pp. 603-618
-
-
Sakuma, T.1
Barry, M.A.2
Ikeda, Y.3
-
5
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R, (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
6
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison PJ, Caudy AA, Bernstein E, Hannon GJ, Conklin DS, (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 16: 948-958.
-
(2002)
Genes Dev
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
8
-
-
31744445721
-
A versatile tool for conditional gene expression and knockdown
-
Szulc J, Wiznerowicz M, Sauvain MO, Trono D, Aebischer P, (2006) A versatile tool for conditional gene expression and knockdown. Nat Methods 3: 109-116.
-
(2006)
Nat Methods
, vol.3
, pp. 109-116
-
-
Szulc, J.1
Wiznerowicz, M.2
Sauvain, M.O.3
Trono, D.4
Aebischer, P.5
-
9
-
-
33747778686
-
Tuning silence: conditional systems for RNA interference
-
Wiznerowicz M, Szulc J, Trono D, (2006) Tuning silence: conditional systems for RNA interference. Nat Methods 3: 682-688.
-
(2006)
Nat Methods
, vol.3
, pp. 682-688
-
-
Wiznerowicz, M.1
Szulc, J.2
Trono, D.3
-
10
-
-
24944560377
-
A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
-
Stegmeier F, Hu G, Rickles RJ, Hannon GJ, Elledge SJ, (2005) A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc Natl Acad Sci U S A 102: 13212-13217.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13212-13217
-
-
Stegmeier, F.1
Hu, G.2
Rickles, R.J.3
Hannon, G.J.4
Elledge, S.J.5
-
11
-
-
33747754760
-
Lessons from Nature: microRNA-based shRNA libraries
-
Chang K, Elledge SJ, Hannon GJ, (2006) Lessons from Nature: microRNA-based shRNA libraries. Nat Methods 3: 707-714.
-
(2006)
Nat Methods
, vol.3
, pp. 707-714
-
-
Chang, K.1
Elledge, S.J.2
Hannon, G.J.3
-
12
-
-
0025085655
-
Ligation-independent cloning of PCR products (LIC-PCR)
-
Aslanidis C, de Jong PJ, (1990) Ligation-independent cloning of PCR products (LIC-PCR). Nucleic Acids Res 18: 6069-6074.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 6069-6074
-
-
Aslanidis, C.1
de Jong, P.J.2
-
13
-
-
0028605713
-
Novel approach to molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase
-
Shuman S, (1994) Novel approach to molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase. J Biol Chem 269: 32678-32684.
-
(1994)
J Biol Chem
, vol.269
, pp. 32678-32684
-
-
Shuman, S.1
-
14
-
-
0028945025
-
Novel methods for cloning and engineering genes using the polymerase chain reaction
-
Rashtchian A, (1995) Novel methods for cloning and engineering genes using the polymerase chain reaction. Curr Opin Biotechnol 6: 30-36.
-
(1995)
Curr Opin Biotechnol
, vol.6
, pp. 30-36
-
-
Rashtchian, A.1
-
15
-
-
34247846396
-
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications
-
Berrow NS, Alderton D, Sainsbury S, Nettleship J, Assenberg R, et al. (2007) A versatile ligation-independent cloning method suitable for high-throughput expression screening applications. Nucleic Acids Res 35: e45.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Berrow, N.S.1
Alderton, D.2
Sainsbury, S.3
Nettleship, J.4
Assenberg, R.5
-
16
-
-
78349289201
-
A ligation-independent cloning method using nicking DNA endonuclease
-
Yang J, Zhang Z, Zhang XA, Luo Q, (2010) A ligation-independent cloning method using nicking DNA endonuclease. Biotechniques 49: 817-821.
-
(2010)
Biotechniques
, vol.49
, pp. 817-821
-
-
Yang, J.1
Zhang, Z.2
Zhang, X.A.3
Luo, Q.4
-
17
-
-
0033676098
-
DNA cloning using in vitro site-specific recombination
-
Hartley JL, Temple GF, Brasch MA, (2000) DNA cloning using in vitro site-specific recombination. Genome Res 10: 1788-1795.
-
(2000)
Genome Res
, vol.10
, pp. 1788-1795
-
-
Hartley, J.L.1
Temple, G.F.2
Brasch, M.A.3
-
18
-
-
0019748408
-
Strand exchange in lambda integrative recombination: genetics, biochemistry, and models
-
Nash HA, Mizuuchi K, Enquist LW, Weisberg RA, (1981) Strand exchange in lambda integrative recombination: genetics, biochemistry, and models. Cold Spring Harb Symp Quant Biol 45 Pt 1: 417-428.
-
(1981)
Cold Spring Harb Symp Quant Biol 45 Pt
, vol.1
, pp. 417-428
-
-
Nash, H.A.1
Mizuuchi, K.2
Enquist, L.W.3
Weisberg, R.A.4
-
19
-
-
0025761119
-
The 41 carboxy-terminal residues of the miniF plasmid CcdA protein are sufficient to antagonize the killer activity of the CcdB protein
-
Bernard P, Couturier M, (1991) The 41 carboxy-terminal residues of the miniF plasmid CcdA protein are sufficient to antagonize the killer activity of the CcdB protein. Mol Gen Genet 226: 297-304.
-
(1991)
Mol Gen Genet
, vol.226
, pp. 297-304
-
-
Bernard, P.1
Couturier, M.2
-
20
-
-
0026728290
-
Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes
-
Bernard P, Couturier M, (1992) Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes. J Mol Biol 226: 735-745.
-
(1992)
J Mol Biol
, vol.226
, pp. 735-745
-
-
Bernard, P.1
Couturier, M.2
-
21
-
-
7444236455
-
Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones
-
Cheo DL, Titus SA, Byrd DR, Hartley JL, Temple GF, et al. (2004) Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones. Genome Res 14: 2111-2120.
-
(2004)
Genome Res
, vol.14
, pp. 2111-2120
-
-
Cheo, D.L.1
Titus, S.A.2
Byrd, D.R.3
Hartley, J.L.4
Temple, G.F.5
-
22
-
-
0025809486
-
New pUC-derived cloning vectors with different selectable markers and DNA replication origins
-
Vieira J, Messing J, (1991) New pUC-derived cloning vectors with different selectable markers and DNA replication origins. Gene 100: 189-194.
-
(1991)
Gene
, vol.100
, pp. 189-194
-
-
Vieira, J.1
Messing, J.2
-
23
-
-
33144454419
-
Development of a new bicistronic retroviral vector with strong IRES activity
-
Martin P, Albagli O, Poggi MC, Boulukos KE, Pognonec P, (2006) Development of a new bicistronic retroviral vector with strong IRES activity. BMC Biotechnol 6: 4.
-
(2006)
BMC Biotechnol
, vol.6
, pp. 4
-
-
Martin, P.1
Albagli, O.2
Poggi, M.C.3
Boulukos, K.E.4
Pognonec, P.5
-
24
-
-
0346132122
-
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
-
Yu SF, von Ruden T, Kantoff PW, Garber C, Seiberg M, et al. (1986) Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proc Natl Acad Sci U S A 83: 3194-3198.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 3194-3198
-
-
Yu, S.F.1
von Ruden, T.2
Kantoff, P.W.3
Garber, C.4
Seiberg, M.5
-
25
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, et al. (1998) Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 72: 9873-9880.
-
(1998)
J Virol
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
Bukovsky, A.4
Quiroz, D.5
-
26
-
-
39749163245
-
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
-
Xiao C, Srinivasan L, Calado DP, Patterson HC, Zhang B, et al. (2008) Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 9: 405-414.
-
(2008)
Nat Immunol
, vol.9
, pp. 405-414
-
-
Xiao, C.1
Srinivasan, L.2
Calado, D.P.3
Patterson, H.C.4
Zhang, B.5
-
27
-
-
27644436787
-
Second-generation shRNA libraries covering the mouse and human genomes
-
Silva JM, Li MZ, Chang K, Ge W, Golding MC, et al. (2005) Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet 37: 1281-1288.
-
(2005)
Nat Genet
, vol.37
, pp. 1281-1288
-
-
Silva, J.M.1
Li, M.Z.2
Chang, K.3
Ge, W.4
Golding, M.C.5
-
28
-
-
84858382422
-
A pipeline for the generation of shRNA transgenic mice
-
Dow LE, Premsrirut PK, Zuber J, Fellmann C, McJunkin K, et al. (2012) A pipeline for the generation of shRNA transgenic mice. Nat Protoc 7: 374-393.
-
(2012)
Nat Protoc
, vol.7
, pp. 374-393
-
-
Dow, L.E.1
Premsrirut, P.K.2
Zuber, J.3
Fellmann, C.4
McJunkin, K.5
-
29
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, et al. (2000) Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev 14: 3037-3050.
-
(2000)
Genes Dev
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
-
30
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine
-
Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, et al. (1995) A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A 92: 7297-7301.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
-
31
-
-
33747156647
-
A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays
-
Hampf M, Gossen M, (2006) A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays. Anal Biochem 356: 94-99.
-
(2006)
Anal Biochem
, vol.356
, pp. 94-99
-
-
Hampf, M.1
Gossen, M.2
-
32
-
-
0034660683
-
A noncommercial dual luciferase enzyme assay system for reporter gene analysis
-
Dyer BW, Ferrer FA, Klinedinst DK, Rodriguez R, (2000) A noncommercial dual luciferase enzyme assay system for reporter gene analysis. Anal Biochem 282: 158-161.
-
(2000)
Anal Biochem
, vol.282
, pp. 158-161
-
-
Dyer, B.W.1
Ferrer, F.A.2
Klinedinst, D.K.3
Rodriguez, R.4
-
33
-
-
68149157175
-
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
-
DuPage M, Dooley AL, Jacks T, (2009) Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc 4: 1064-1072.
-
(2009)
Nat Protoc
, vol.4
, pp. 1064-1072
-
-
DuPage, M.1
Dooley, A.L.2
Jacks, T.3
-
34
-
-
0038359205
-
Safety and efficiency of modulating paracellular permeability to enhance airway epithelial gene transfer in vivo
-
Johnson LG, Vanhook MK, Coyne CB, Haykal-Coates N, Gavett SH, (2003) Safety and efficiency of modulating paracellular permeability to enhance airway epithelial gene transfer in vivo. Hum Gene Ther 14: 729-747.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 729-747
-
-
Johnson, L.G.1
Vanhook, M.K.2
Coyne, C.B.3
Haykal-Coates, N.4
Gavett, S.H.5
-
35
-
-
33847201454
-
A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors
-
Dankort D, Filenova E, Collado M, Serrano M, Jones K, et al. (2007) A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors. Genes Dev 21: 379-384.
-
(2007)
Genes Dev
, vol.21
, pp. 379-384
-
-
Dankort, D.1
Filenova, E.2
Collado, M.3
Serrano, M.4
Jones, K.5
-
36
-
-
80052882155
-
Advances in Gene Delivery Systems
-
Kamimura K, Suda T, Zhang G, Liu D, (2011) Advances in Gene Delivery Systems. Pharmaceut Med 25: 293-306.
-
(2011)
Pharmaceut Med
, vol.25
, pp. 293-306
-
-
Kamimura, K.1
Suda, T.2
Zhang, G.3
Liu, D.4
-
37
-
-
68449083213
-
A versatile viral system for expression and depletion of proteins in mammalian cells
-
Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, et al. (2009) A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS ONE 4: e6529.
-
(2009)
PLoS ONE
, vol.4
-
-
Campeau, E.1
Ruhl, V.E.2
Rodier, F.3
Smith, C.L.4
Rahmberg, B.L.5
-
38
-
-
31444448624
-
E unum pluribus: multiple proteins from a self-processing polyprotein
-
de Felipe P, Luke GA, Hughes LE, Gani D, Halpin C, et al. (2006) E unum pluribus: multiple proteins from a self-processing polyprotein. Trends Biotechnol 24: 68-75.
-
(2006)
Trends Biotechnol
, vol.24
, pp. 68-75
-
-
de Felipe, P.1
Luke, G.A.2
Hughes, L.E.3
Gani, D.4
Halpin, C.5
-
39
-
-
53149149440
-
Use of the viral 2A peptide for bicistronic expression in transgenic mice
-
Trichas G, Begbie J, Srinivas S, (2008) Use of the viral 2A peptide for bicistronic expression in transgenic mice. BMC Biol 6: 40.
-
(2008)
BMC Biol
, vol.6
, pp. 40
-
-
Trichas, G.1
Begbie, J.2
Srinivas, S.3
-
40
-
-
0035015174
-
Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip
-
Donnelly ML, Luke G, Mehrotra A, Li X, Hughes LE, et al. (2001) Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. J Gen Virol 82: 1013-1025.
-
(2001)
J Gen Virol
, vol.82
, pp. 1013-1025
-
-
Donnelly, M.L.1
Luke, G.2
Mehrotra, A.3
Li, X.4
Hughes, L.E.5
-
41
-
-
0025934319
-
Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence
-
Ryan MD, King AM, Thomas GP, (1991) Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence. J Gen Virol 72 (Pt 11): 2727-2732.
-
(1991)
J Gen Virol
, vol.72
, Issue.Pt 11
, pp. 2727-2732
-
-
Ryan, M.D.1
King, A.M.2
Thomas, G.P.3
-
42
-
-
0033453239
-
Attenuation of green fluorescent protein half-life in mammalian cells
-
Corish P, Tyler-Smith C, (1999) Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng 12: 1035-1040.
-
(1999)
Protein Eng
, vol.12
, pp. 1035-1040
-
-
Corish, P.1
Tyler-Smith, C.2
-
43
-
-
0037710130
-
High stability of Discosoma DsRed as compared to Aequorea EGFP
-
Verkhusha VV, Kuznetsova IM, Stepanenko OV, Zaraisky AG, Shavlovsky MM, et al. (2003) High stability of Discosoma DsRed as compared to Aequorea EGFP. Biochemistry 42: 7879-7884.
-
(2003)
Biochemistry
, vol.42
, pp. 7879-7884
-
-
Verkhusha, V.V.1
Kuznetsova, I.M.2
Stepanenko, O.V.3
Zaraisky, A.G.4
Shavlovsky, M.M.5
-
44
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, Dickins RA, Hernando E, et al. (2007) Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445: 656-660.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
-
46
-
-
70349438994
-
Tumour suppression by p53: a role for the DNA damage response?
-
Meek DW, (2009) Tumour suppression by p53: a role for the DNA damage response? Nat Rev Cancer 9: 714-723.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 714-723
-
-
Meek, D.W.1
-
47
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE, (1993) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
49
-
-
12644303224
-
Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G
-
Tarun SZ Jr, Sachs AB, (1996) Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G. Embo J 15: 7168-7177.
-
(1996)
Embo J
, vol.15
, pp. 7168-7177
-
-
Tarun Jr., S.Z.1
Sachs, A.B.2
-
50
-
-
0030952218
-
Translation initiation factors eIF-iso4G and eIF-4B interact with the poly(A)-binding protein and increase its RNA binding activity
-
Le H, Tanguay RL, Balasta ML, Wei CC, Browning KS, et al. (1997) Translation initiation factors eIF-iso4G and eIF-4B interact with the poly(A)-binding protein and increase its RNA binding activity. J Biol Chem 272: 16247-16255.
-
(1997)
J Biol Chem
, vol.272
, pp. 16247-16255
-
-
Le, H.1
Tanguay, R.L.2
Balasta, M.L.3
Wei, C.C.4
Browning, K.S.5
-
51
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis
-
Landthaler M, Yalcin A, Tuschl T, (2004) The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14: 2162-2167.
-
(2004)
Curr Biol
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
52
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen NJ, Parrish S, Imani F, Fire A, Morgan RA, (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci U S A 98: 9742-9747.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
53
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA, (1999) Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 13: 3191-3197.
-
(1999)
Genes Dev
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
54
-
-
0023084783
-
Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system
-
DuBridge RB, Tang P, Hsia HC, Leong PM, Miller JH, et al. (1987) Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol Cell Biol 7: 379-387.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 379-387
-
-
DuBridge, R.B.1
Tang, P.2
Hsia, H.C.3
Leong, P.M.4
Miller, J.H.5
-
55
-
-
0032582477
-
Infectious human papillomavirus type 18 pseudovirions
-
Stauffer Y, Raj K, Masternak K, Beard P, (1998) Infectious human papillomavirus type 18 pseudovirions. J Mol Biol 283: 529-536.
-
(1998)
J Mol Biol
, vol.283
, pp. 529-536
-
-
Stauffer, Y.1
Raj, K.2
Masternak, K.3
Beard, P.4
-
56
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS, (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
57
-
-
34548186667
-
Cellular senescence: when bad things happen to good cells
-
Campisi J, d'Adda di Fagagna F, (2007) Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 8: 729-740.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
d'Adda di Fagagna, F.2
-
58
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, et al. (1998) Extension of life-span by introduction of telomerase into normal human cells. Science 279: 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
-
59
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW, (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
60
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW, (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88: 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
61
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, et al. (1999) Creation of human tumour cells with defined genetic elements. Nature 400: 464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
-
62
-
-
25144514580
-
C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence
-
Sebastian T, Malik R, Thomas S, Sage J, Johnson PF, (2005) C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence. Embo J 24: 3301-3312.
-
(2005)
Embo J
, vol.24
, pp. 3301-3312
-
-
Sebastian, T.1
Malik, R.2
Thomas, S.3
Sage, J.4
Johnson, P.F.5
-
63
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, et al. (1997) Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91: 649-659.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
-
65
-
-
0035412401
-
Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
-
Van Tendeloo VF, Ponsaerts P, Lardon F, Nijs G, Lenjou M, et al. (2001) Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 98: 49-56.
-
(2001)
Blood
, vol.98
, pp. 49-56
-
-
Van Tendeloo, V.F.1
Ponsaerts, P.2
Lardon, F.3
Nijs, G.4
Lenjou, M.5
-
66
-
-
0034921818
-
Cationic lipid-mediated transfection in vitro and in vivo (review)
-
Audouy S, Hoekstra D, (2001) Cationic lipid-mediated transfection in vitro and in vivo (review). Mol Membr Biol 18: 129-143.
-
(2001)
Mol Membr Biol
, vol.18
, pp. 129-143
-
-
Audouy, S.1
Hoekstra, D.2
-
67
-
-
0030663073
-
Adenoviral vectors for gene transfer
-
Kovesdi I, Brough DE, Bruder JT, Wickham TJ, (1997) Adenoviral vectors for gene transfer. Curr Opin Biotechnol 8: 583-589.
-
(1997)
Curr Opin Biotechnol
, vol.8
, pp. 583-589
-
-
Kovesdi, I.1
Brough, D.E.2
Bruder, J.T.3
Wickham, T.J.4
-
68
-
-
1642450247
-
Sendai virus vectors as an emerging negative-strand RNA viral vector system
-
Bitzer M, Armeanu S, Lauer UM, Neubert WJ, (2003) Sendai virus vectors as an emerging negative-strand RNA viral vector system. J Gene Med 5: 543-553.
-
(2003)
J Gene Med
, vol.5
, pp. 543-553
-
-
Bitzer, M.1
Armeanu, S.2
Lauer, U.M.3
Neubert, W.J.4
-
70
-
-
68649119307
-
Strategies for the episomal modification of cells
-
Wong SP, Argyros O, Coutelle C, Harbottle RP, (2009) Strategies for the episomal modification of cells. Curr Opin Mol Ther 11: 433-441.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 433-441
-
-
Wong, S.P.1
Argyros, O.2
Coutelle, C.3
Harbottle, R.P.4
-
71
-
-
44049103962
-
Adeno-associated virus integration: virus versus vector
-
Smith RH, (2008) Adeno-associated virus integration: virus versus vector. Gene Ther 15: 817-822.
-
(2008)
Gene Ther
, vol.15
, pp. 817-822
-
-
Smith, R.H.1
-
72
-
-
68649111166
-
Adeno-associated virus vector integration
-
Deyle DR, Russell DW, (2009) Adeno-associated virus vector integration. Curr Opin Mol Ther 11: 442-447.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 442-447
-
-
Deyle, D.R.1
Russell, D.W.2
-
73
-
-
23744479962
-
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
-
Ding S, Wu X, Li G, Han M, Zhuang Y, et al. (2005) Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell 122: 473-483.
-
(2005)
Cell
, vol.122
, pp. 473-483
-
-
Ding, S.1
Wu, X.2
Li, G.3
Han, M.4
Zhuang, Y.5
-
74
-
-
0030662074
-
Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
-
Ivics Z, Hackett PB, Plasterk RH, Izsvak Z, (1997) Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91: 501-510.
-
(1997)
Cell
, vol.91
, pp. 501-510
-
-
Ivics, Z.1
Hackett, P.B.2
Plasterk, R.H.3
Izsvak, Z.4
-
75
-
-
0036835931
-
Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction
-
Mitta B, Rimann M, Ehrengruber MU, Ehrbar M, Djonov V, et al. (2002) Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction. Nucleic Acids Res 30: e113.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Mitta, B.1
Rimann, M.2
Ehrengruber, M.U.3
Ehrbar, M.4
Djonov, V.5
-
76
-
-
0043210428
-
Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference
-
Wiznerowicz M, Trono D, (2003) Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol 77: 8957-8961.
-
(2003)
J Virol
, vol.77
, pp. 8957-8961
-
-
Wiznerowicz, M.1
Trono, D.2
-
77
-
-
33748758189
-
A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression
-
Shin KJ, Wall EA, Zavzavadjian JR, Santat LA, Liu J, et al. (2006) A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression. Proc Natl Acad Sci U S A 103: 13759-13764.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13759-13764
-
-
Shin, K.J.1
Wall, E.A.2
Zavzavadjian, J.R.3
Santat, L.A.4
Liu, J.5
-
78
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
Gupta S, Schoer RA, Egan JE, Hannon GJ, Mittal V, (2004) Inducible, reversible, and stable RNA interference in mammalian cells. Proc Natl Acad Sci U S A 101: 1927-1932.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
79
-
-
77955661669
-
Multipurpose modular lentiviral vectors for RNA interference and transgene expression
-
Kesireddy V, van der Ven PF, Furst DO, (2010) Multipurpose modular lentiviral vectors for RNA interference and transgene expression. Mol Biol Rep 37: 2863-2870.
-
(2010)
Mol Biol Rep
, vol.37
, pp. 2863-2870
-
-
Kesireddy, V.1
van der Ven, P.F.2
Furst, D.O.3
-
80
-
-
41149099102
-
A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis
-
Weber K, Bartsch U, Stocking C, Fehse B, (2008) A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis. Mol Ther 16: 698-706.
-
(2008)
Mol Ther
, vol.16
, pp. 698-706
-
-
Weber, K.1
Bartsch, U.2
Stocking, C.3
Fehse, B.4
-
81
-
-
79952303452
-
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
-
Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, et al. (2011) The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A 108: 3665-3670.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3665-3670
-
-
Meerbrey, K.L.1
Hu, G.2
Kessler, J.D.3
Roarty, K.4
Li, M.Z.5
-
82
-
-
36448963734
-
The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
-
Kwan KM, Fujimoto E, Grabher C, Mangum BD, Hardy ME, et al. (2007) The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn 236: 3088-3099.
-
(2007)
Dev Dyn
, vol.236
, pp. 3088-3099
-
-
Kwan, K.M.1
Fujimoto, E.2
Grabher, C.3
Mangum, B.D.4
Hardy, M.E.5
-
83
-
-
0033732564
-
GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes
-
Walhout AJ, Temple GF, Brasch MA, Hartley JL, Lorson MA, et al. (2000) GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes. Methods Enzymol 328: 575-592.
-
(2000)
Methods Enzymol
, vol.328
, pp. 575-592
-
-
Walhout, A.J.1
Temple, G.F.2
Brasch, M.A.3
Hartley, J.L.4
Lorson, M.A.5
-
85
-
-
0029071190
-
Efficient screening of retroviral cDNA expression libraries
-
Kitamura T, Onishi M, Kinoshita S, Shibuya A, Miyajima A, et al. (1995) Efficient screening of retroviral cDNA expression libraries. Proc Natl Acad Sci U S A 92: 9146-9150.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9146-9150
-
-
Kitamura, T.1
Onishi, M.2
Kinoshita, S.3
Shibuya, A.4
Miyajima, A.5
-
86
-
-
38949193234
-
Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5
-
Chen Y, Gorski DH, (2008) Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 111: 1217-1226.
-
(2008)
Blood
, vol.111
, pp. 1217-1226
-
-
Chen, Y.1
Gorski, D.H.2
|