eIF2α phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation

Journal of Neuroscience

Volumn 30, Issue 7, 2010, Pages 2582-2594

  Jiang, Zhihong ^a   Belforte, Juan E ^a   Lu, Yuan ^a   Yabe, Yoko ^a   Pickel, James ^a   Smith, Carolyn Beebe ^a   Je, Hyun Soo ^b   Lu, Bai ^a,b   Nakazawa, Kazu ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ANISOMYCIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INITIATION FACTOR 2ALPHA; PROTEIN KINASE R; 2 HYDROXY 4,4' DIAMIDINOSTILBENE, METHANESULFONATE SALT; 2-HYDROXY-4,4'-DIAMIDINOSTILBENE, METHANESULFONATE SALT; AP20187; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DRUG DERIVATIVE; INITIATION FACTOR 2; MICROTUBULE ASSOCIATED PROTEIN; MTAP2 PROTEIN, MOUSE; PROTEIN C FOS; PROTEIN KINASE; PROTEIN SYNTHESIS INHIBITOR; STILBAMIDINE; TACROLIMUS; TCF4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENETIC MANIPULATION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PYRAMIDAL NERVE CELL; RNA TRANSLATION; SYNAPSE; ANALYSIS OF VARIANCE; ANIMAL; AVOIDANCE BEHAVIOR; BIOPHYSICS; CONDITIONING; DOSE RESPONSE; DRUG EFFECT; ELECTROSTIMULATION; ENZYME ACTIVATION; FEAR; GENE EXPRESSION REGULATION; GENETICS; IN VITRO STUDY; LONG TERM POTENTIATION; MAZE TEST; MEMORY DISORDER; METABOLISM; MUTATION; NONPARAMETRIC TEST; PATCH CLAMP; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; ANISOMYCIN; AVOIDANCE LEARNING; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BIOPHYSICS; CONDITIONING (PSYCHOLOGY); CREB-BINDING PROTEIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; FEAR; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-FOS; PYRAMIDAL CELLS; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; STILBAMIDINES; TACROLIMUS;

EID: 77249127919     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3971-09.2010     Document Type: Article

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