Failures to reconsolidate memory in a mouse model of Alzheimer's disease

Neurobiology of Learning and Memory

Volumn 92, Issue 3, 2009, Pages 455-459

  Ohno, Masuo ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5XFAD mice; Alzheimer's disease; Amnesia; Amyloid; APP transgenic; Fear conditioning; Reconsolidation

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; GENE MUTATION; HIPPOCAMPUS; LEARNING; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; RECALL; RETROGRADE AMNESIA; TRANSGENIC MOUSE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; FEAR; HUMANS; LEARNING DISORDERS; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; MUTATION; PRESENILIN-1; RECEPTORS, CELL SURFACE;

EID: 69249216440     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nlm.2009.05.001     Document Type: Article

References (40)

1. Alberini C.M. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes?. Trends in Neuroscience 28 (2005) 51-56
2. Ashe K.H. Learning and memory in transgenic mice modeling Alzheimer's disease. Learning and Memory 8 (2001) 301-308
3. 751SL mice results in cue-guided response. Neurobiology of Aging 29 (2008) 1011-1021
4. Dewachter I., Filipkowski R.K., Priller C., Ris L., Neyton J., Croes S., et al. Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice. Neurobiology of Aging 30 (2009) 241-256
5. Dickey C.A., Gordon M.N., Mason J.E., Wilson N.J., Diamond D.M., Guzowski J.F., et al. Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice. Journal of Neurochemistry 88 (2004) 434-442
6. Dickey C.A., Loring J.F., Montgomery J., Gordon M.N., Eastman P.S., and Morgan D. Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice. Journal of Neuroscience 23 (2003) 5219-5226
7. Dudai Y. The neurobiology of consolidations, or, how stable is the engram?. Annual Review of Psychology 55 (2004) 51-86
8. Dudai Y. Reconsolidation: The advantage of being refocused. Current Opinion in Neurobiology 16 (2006) 174-178
9. Duvarci S., Nader K., and LeDoux J.E. Activation of extracellular signal-regulated kinase-mitogen-activated protein kinase cascade in the amygdala is required for memory reconsolidation of auditory fear conditioning. European Journal of Neuroscience 21 (2005) 283-289
10. Eisenberg M., Kobilo T., Berman D.E., and Dudai Y. Stability of retrieved memory: Inverse correlation with trace dominance. Science 301 (2003) 1102-1104
11. Eriksen J.L., and Janus C.G. Plaques, tangles, and memory loss in mouse models of neurodegeneration. Behavior Genetics 37 (2007) 79-100
12. Fanselow M.S. Contextual fear, gestalt memories, and the hippocampus. Behavioural Brain Research 110 (2000) 73-81
13. Frankland P.W., and Bontempi B. The organization of recent and remote memories. Nature Reviews Neuroscience 6 (2005) 119-130
14. Gong B., Cao Z., Zheng P., Vitolo O.V., Liu S., Staniszewski A., et al. Ubiquitin hydrolase Uch-L1 rescues β-amyloid-induced decreases in synaptic function and contextual memory. Cell 126 (2006) 775-788
15. Gong B., Vitolo O.V., Trinchese F., Liu S., Shelanski M., and Arancio O. Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment. Journal of Clinical Investigation 114 (2004) 1624-1634
16. Gotz J., and Ittner L.M. Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience 9 (2008) 532-544
17. Kida S., Josselyn S.A., de Ortiz S.P., Kogan J.H., Chevere I., Masushige S., et al. CREB required for the stability of new and reactivated fear memories. Nature Neuroscience 5 (2002) 348-355
18. Kimura R., and Ohno M. Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model. Neurobiology of Disease 33 (2009) 229-235
19. Kimura R., Silva A.J., and Ohno M. Autophosphorylation of αCaMKII is differentially involved in new learning and unlearning mechanisms of memory extinction. Learning and Memory 15 (2008) 837-843
20. Kobayashi D.T., and Chen K.S. Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease. Genes, Brain and Behavior 4 (2005) 173-196
21. LaFerla F.M., and Oddo S. Alzheimer's disease: Aβ, tau and synaptic dysfunction. Trends in Molecular Medicine 11 (2005) 170-176
22. Lee J.L. Memory reconsolidation mediates the strengthening of memories by additional learning. Nature Neuroscience 11 (2008) 1264-1266
23. Lee J.L., Everitt B.J., and Thomas K.L. Independent cellular processes for hippocampal memory consolidation and reconsolidation. Science 304 (2004) 839-843
24. Ma Q.L., Harris-White M.E., Ubeda O.J., Simmons M., Beech W., Lim G.P., et al. Evidence of Aβ- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models. Journal of Neurochemistry 103 (2007) 1594-1607
25. Mamiya N., Fukushima H., Suzuki A., Matsuyama Z., Homma S., Frankland P.W., et al. Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory. Journal of Neuroscience 29 (2009) 402-413
26. McClelland J.L., McNaughton B.L., and O'Reilly R.C. Why there are complementary learning systems in the hippocampus and neocortex: Insights from the successes and failures of connectionist models of learning and memory. Psychological Review 102 (1995) 419-457
27. McGowan E., Eriksen J., and Hutton M. A decade of modeling Alzheimer's disease in transgenic mice. Trends in Genetics 22 (2006) 281-289
28. Nader K. Memory traces unbound. Trends in Neuroscience 26 (2003) 65-72
29. Nader K., Schafe G.E., and Le Doux J.E. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406 (2000) 722-726
30. Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., et al. Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation. Journal of Neuroscience 26 (2006) 10129-10140
31. Ohno M. Genetic and pharmacological basis for therapeutic inhibition of β- and g-secretases in mouse models of Alzheimer's memory deficits. Reviews in the Neurosciences 17 (2006) 429-454
32. Ohno M., Chang L., Tseng W., Oakley H., Citron M., Klein W.L., et al. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1. European Journal of Neuroscience 23 (2006) 251-260
33. Ohno M., Cole S.L., Yasvoina M., Zhao J., Citron M., Berry R., et al. BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice. Neurobiology of Disease 26 (2007) 134-145
34. Ohno M., Frankland P.W., Chen A.P., Costa R.M., and Silva A.J. Inducible, pharmacogenetic approaches to the study of learning and memory. Nature Neuroscience 4 (2001) 1238-1243
35. Snyder E.M., Nong Y., Almeida C.G., Paul S., Moran T., Choi E.Y., et al. Regulation of NMDA receptor trafficking by amyloid-β. Nature Neuroscience 8 (2005) 1051-1058
36. Squire L.R., and Bayley P.J. The neuroscience of remote memory. Current Opinion in Neurobiology 17 (2007) 185-196
37. Suzuki A., Josselyn S.A., Frankland P.W., Masushige S., Silva A.J., and Kida S. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. Journal of Neuroscience 24 (2004) 4787-4795
38. Tronson N.C., and Taylor J.R. Molecular mechanisms of memory reconsolidation. Nature Reviews Neuroscience 8 (2007) 262-275
39. Tronson N.C., Wiseman S.L., Olausson P., and Taylor J.R. Bidirectional behavioral plasticity of memory reconsolidation depends on amygdalar protein kinase A. Nature Neuroscience 9 (2006) 167-169
40. Wu Z.L., Ciallella J.R., Flood D.G., O'Kane T.M., Bozyczko-Coyne D., and Savage M.J. Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease. Neurobiology of Aging 27 (2006) 377-386