메뉴 건너뛰기




Volumn 62, Issue 6, 2013, Pages 639-646

Transport proteins of the ABC systems superfamily and their role in drug action and resistance in nematodes

Author keywords

ABC systems; ABC transporter; Drug resistance; Nematode; P glycoprotein

Indexed keywords

ABC TRANSPORTER; ANTHELMINTIC AGENT; BENZIMIDAZOLE; CAMBENDAZOLE; CARRIER PROTEIN; CHLOROQUINE; IVERMECTIN; KETOCONAZOLE; LEVAMISOLE; MILBEMYCIN; MOXIDECTIN; MULTIDRUG RESISTANCE PROTEIN; POLOXAMER; ANTINEMATODAL AGENT;

EID: 84885374641     PISSN: 13835769     EISSN: 18730329     Source Type: Journal    
DOI: 10.1016/j.parint.2013.02.008     Document Type: Review
Times cited : (43)

References (92)
  • 1
    • 53849096994 scopus 로고    scopus 로고
    • An overview of cancer multidrug resistance: a still unsolved problem
    • Lage H. An overview of cancer multidrug resistance: a still unsolved problem. Cellular and Molecular Life Sciences 2008, 65(20):3145-3167.
    • (2008) Cellular and Molecular Life Sciences , vol.65 , Issue.20 , pp. 3145-3167
    • Lage, H.1
  • 2
    • 79960938721 scopus 로고    scopus 로고
    • Bacterial resistance mechanisms against host defense peptides
    • Koprivnjak T., Peschel A. Bacterial resistance mechanisms against host defense peptides. Cellular and Molecular Life Sciences 2011, 68(13):2243-2254.
    • (2011) Cellular and Molecular Life Sciences , vol.68 , Issue.13 , pp. 2243-2254
    • Koprivnjak, T.1    Peschel, A.2
  • 3
    • 34147214716 scopus 로고    scopus 로고
    • Multiple molecular mechanisms for multidrug resistance transporters
    • Higgins C.F. Multiple molecular mechanisms for multidrug resistance transporters. Nature Reviews 2007, 446:749-757.
    • (2007) Nature Reviews , vol.446 , pp. 749-757
    • Higgins, C.F.1
  • 4
    • 64649085938 scopus 로고    scopus 로고
    • Multidrug efflux transporters in the MATE family
    • Kuroda T., Tsuchiya T. Multidrug efflux transporters in the MATE family. Biochemica et Biophysica Acta 2009, 1794:763-768.
    • (2009) Biochemica et Biophysica Acta , vol.1794 , pp. 763-768
    • Kuroda, T.1    Tsuchiya, T.2
  • 8
    • 34250196496 scopus 로고    scopus 로고
    • Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two phase epidemiological study
    • Osei-Atweneboana M.Y., Eng J.K.L., Boakye D.A., Gyapong J.O., Prichard R.K. Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two phase epidemiological study. Lancet 2007, 369:2021-2029.
    • (2007) Lancet , vol.369 , pp. 2021-2029
    • Osei-Atweneboana, M.Y.1    Eng, J.K.L.2    Boakye, D.A.3    Gyapong, J.O.4    Prichard, R.K.5
  • 10
    • 10644263172 scopus 로고    scopus 로고
    • Genetic variability of glutamate-gated chloride channel genes in ivermectin-susceptible and -resistant strains of Cooperia oncophora
    • Njue A., Prichard R.K. Genetic variability of glutamate-gated chloride channel genes in ivermectin-susceptible and -resistant strains of Cooperia oncophora. Parasitology 2004, 129:741-751.
    • (2004) Parasitology , vol.129 , pp. 741-751
    • Njue, A.1    Prichard, R.K.2
  • 11
    • 0141428987 scopus 로고    scopus 로고
    • Selection at a gamma-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins
    • Blackhall W.J., Prichard R.K., Beech R.N. Selection at a gamma-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins. Molecular and Biochemical Parasitology 2003, 131:137-145.
    • (2003) Molecular and Biochemical Parasitology , vol.131 , pp. 137-145
    • Blackhall, W.J.1    Prichard, R.K.2    Beech, R.N.3
  • 13
    • 84870864541 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin
    • Ardelli B.F., Prichard R.K. Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin. Veterinary Parasitology 2013, 191:264-275.
    • (2013) Veterinary Parasitology , vol.191 , pp. 264-275
    • Ardelli, B.F.1    Prichard, R.K.2
  • 14
    • 0035014565 scopus 로고    scopus 로고
    • The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms
    • Dassa E., Bouige P. The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms. Research in Microbiology 2001, 152:211-229.
    • (2001) Research in Microbiology , vol.152 , pp. 211-229
    • Dassa, E.1    Bouige, P.2
  • 15
    • 0033819143 scopus 로고    scopus 로고
    • The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis
    • Braibant M., Gilot P., Content J. The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis. FEMS Microbiology Reviews 2000, 24:449-467.
    • (2000) FEMS Microbiology Reviews , vol.24 , pp. 449-467
    • Braibant, M.1    Gilot, P.2    Content, J.3
  • 16
    • 0346814102 scopus 로고    scopus 로고
    • Phylogenetic and functional classification of ABC (ATP-binding cassette) systems
    • Academic Press, London, I.B. Holland, S.P.C. Cole, K. Kuchler, C.F. Higgins (Eds.)
    • Dassa E. Phylogenetic and functional classification of ABC (ATP-binding cassette) systems. ABC proteins: from bacteria to man 2003, 3-35. Academic Press, London. I.B. Holland, S.P.C. Cole, K. Kuchler, C.F. Higgins (Eds.).
    • (2003) ABC proteins: from bacteria to man , pp. 3-35
    • Dassa, E.1
  • 17
    • 0033515437 scopus 로고    scopus 로고
    • Inventory, assembly and analysis of Bacillus subtilis ABC transport systems
    • Quentin Y., Fichant G., Denizot F. Inventory, assembly and analysis of Bacillus subtilis ABC transport systems. Journal of Molecular Biology 1999, 287:467-484.
    • (1999) Journal of Molecular Biology , vol.287 , pp. 467-484
    • Quentin, Y.1    Fichant, G.2    Denizot, F.3
  • 18
    • 0032720231 scopus 로고    scopus 로고
    • Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance
    • Bauer B.E., Wolfger H., Kuchler K. Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochimica et Biophysica Acta 1999, 1461:217-236.
    • (1999) Biochimica et Biophysica Acta , vol.1461 , pp. 217-236
    • Bauer, B.E.1    Wolfger, H.2    Kuchler, K.3
  • 19
    • 0031056684 scopus 로고    scopus 로고
    • Complete inventory of the yeast ABC proteins
    • Decottignies A., Goffeau A. Complete inventory of the yeast ABC proteins. Nature genetics 1997, 15:137-145.
    • (1997) Nature genetics , vol.15 , pp. 137-145
    • Decottignies, A.1    Goffeau, A.2
  • 20
    • 0025834782 scopus 로고
    • Isolation and characterization of Drosophila multidrug resistance gene homologs
    • Wu C.T., Budding M., Griffin M.S., Croop J.M. Isolation and characterization of Drosophila multidrug resistance gene homologs. Molecular and Cellular Biology 1991, 11:3940-3948.
    • (1991) Molecular and Cellular Biology , vol.11 , pp. 3940-3948
    • Wu, C.T.1    Budding, M.2    Griffin, M.S.3    Croop, J.M.4
  • 21
    • 0028177555 scopus 로고
    • Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster - implications for structure-function relationships
    • Ewart G.D., Cannell D., Cox G.B., Howells A.J. Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster - implications for structure-function relationships. Journal of Biological Chemistry 1994, 269:10370-10377.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 10370-10377
    • Ewart, G.D.1    Cannell, D.2    Cox, G.B.3    Howells, A.J.4
  • 24
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M., Rzhetsky A., Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Research 2001, 11:1156-1166.
    • (2001) Genome Research , vol.11 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 26
    • 0031751905 scopus 로고    scopus 로고
    • Plasmodium and Leishmania: the role of mdr genes in mediating drug resistance
    • Chow L.M.C., Volkman S.K. Plasmodium and Leishmania: the role of mdr genes in mediating drug resistance. Experimental Parasitology 1998, 90:135-141.
    • (1998) Experimental Parasitology , vol.90 , pp. 135-141
    • Chow, L.M.C.1    Volkman, S.K.2
  • 27
    • 0031882865 scopus 로고    scopus 로고
    • Identification of three ABC transporter genes in Trypanosoma brucei spp
    • Maser P., Kaminsky R. Identification of three ABC transporter genes in Trypanosoma brucei spp. Parasitology Research 1998, 84:106-111.
    • (1998) Parasitology Research , vol.84 , pp. 106-111
    • Maser, P.1    Kaminsky, R.2
  • 28
    • 4444266487 scopus 로고    scopus 로고
    • The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes
    • Sheps J.A., Ralph S., Zhao Z., Baillie D.L., Ling V. The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes. Genome Biology 2004, 5:R15.
    • (2004) Genome Biology , vol.5
    • Sheps, J.A.1    Ralph, S.2    Zhao, Z.3    Baillie, D.L.4    Ling, V.5
  • 29
    • 0001769249 scopus 로고    scopus 로고
    • Periplasmic binding protein-dependent ABC transporters
    • ASM Press, Washington, F.C. Neidhardt (Ed.)
    • Boos W., Lucht J.M. Periplasmic binding protein-dependent ABC transporters. Escherichia coli and Salmonella cellular and molecular biology 1999, 1175-1209. ASM Press, Washington. 2nd ed. F.C. Neidhardt (Ed.).
    • (1999) Escherichia coli and Salmonella cellular and molecular biology , pp. 1175-1209
    • Boos, W.1    Lucht, J.M.2
  • 30
    • 0027132575 scopus 로고
    • ABC transporters - bacterial exporters
    • Fath M.J., Kolter R. ABC transporters - bacterial exporters. Microbiological Reviews 1993, 57:995-1017.
    • (1993) Microbiological Reviews , vol.57 , pp. 995-1017
    • Fath, M.J.1    Kolter, R.2
  • 31
    • 77957363104 scopus 로고    scopus 로고
    • Inventory and analysis of ATP binding cassette (ABC systems) in Brugia malayi
    • Ardelli B.F., Stitt L.E., Tompkins J.B. Inventory and analysis of ATP binding cassette (ABC systems) in Brugia malayi. Parasitology 2010, 137:1-18.
    • (2010) Parasitology , vol.137 , pp. 1-18
    • Ardelli, B.F.1    Stitt, L.E.2    Tompkins, J.B.3
  • 33
    • 59149089885 scopus 로고    scopus 로고
    • The role of ATP binding cassette transporters in tissue defense and organ regeneration
    • Huls M., Russel F.G.M., Masereeuw R. The role of ATP binding cassette transporters in tissue defense and organ regeneration. Perspectives in Pharmacology 2008, 328(1):3-9.
    • (2008) Perspectives in Pharmacology , vol.328 , Issue.1 , pp. 3-9
    • Huls, M.1    Russel, F.G.M.2    Masereeuw, R.3
  • 34
    • 69549103132 scopus 로고    scopus 로고
    • Effects of ivermectin and moxidectin on the transcription of genes coding for multidrug resistance associated proteins and behaviour in Caenorhabditis elegans
    • Ardelli B.F., Prichard R.K. Effects of ivermectin and moxidectin on the transcription of genes coding for multidrug resistance associated proteins and behaviour in Caenorhabditis elegans. Journal of Nematology 2008, 40:290-298.
    • (2008) Journal of Nematology , vol.40 , pp. 290-298
    • Ardelli, B.F.1    Prichard, R.K.2
  • 35
    • 57649087686 scopus 로고    scopus 로고
    • Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans
    • James C.E., Davey M.W. Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans. International Journal of Parasitology 2009, 39:213-220.
    • (2009) International Journal of Parasitology , vol.39 , pp. 213-220
    • James, C.E.1    Davey, M.W.2
  • 36
    • 80052402872 scopus 로고    scopus 로고
    • ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance
    • Stitt L.E., Tompkins J.B., Dooley L.A., Ardelli B.F. ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance. Experimental Parasitology 2011, 129:137-144.
    • (2011) Experimental Parasitology , vol.129 , pp. 137-144
    • Stitt, L.E.1    Tompkins, J.B.2    Dooley, L.A.3    Ardelli, B.F.4
  • 37
    • 82955198399 scopus 로고    scopus 로고
    • The role of Brugia malayi ATP-binding cassette transporters in potentiating drug sensitivity
    • Tompkins J.B., Stitt L.E., Morrissette A.M., Ardelli B.F. The role of Brugia malayi ATP-binding cassette transporters in potentiating drug sensitivity. Parasitology Research 2011, 109(5):1311-1322.
    • (2011) Parasitology Research , vol.109 , Issue.5 , pp. 1311-1322
    • Tompkins, J.B.1    Stitt, L.E.2    Morrissette, A.M.3    Ardelli, B.F.4
  • 38
    • 0001607723 scopus 로고
    • Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker J.E., Saraste M., Runswick M.J., Gay N.J. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO Journal 1982, 1:945-951.
    • (1982) EMBO Journal , vol.1 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.J.4
  • 39
    • 0026621245 scopus 로고
    • ABC transporters: from microorganisms to man
    • Higgins C.F. ABC transporters: from microorganisms to man. Annual Review of Cell Biology 1992, 8:67-113.
    • (1992) Annual Review of Cell Biology , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 40
    • 0035019469 scopus 로고    scopus 로고
    • ABC transporters: physiology, structure and mechanism - an overview
    • Higgins C.F. ABC transporters: physiology, structure and mechanism - an overview. Research in Microbiology 2001, 152:205-210.
    • (2001) Research in Microbiology , vol.152 , pp. 205-210
    • Higgins, C.F.1
  • 41
    • 0031810816 scopus 로고    scopus 로고
    • ATP-binding cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains
    • Schneider E., Hunke S. ATP-binding cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains. FEMS microbiology reviews 1998, 22:1-20.
    • (1998) FEMS microbiology reviews , vol.22 , pp. 1-20
    • Schneider, E.1    Hunke, S.2
  • 42
    • 0037398027 scopus 로고    scopus 로고
    • Rad 50/SMC proteins and ABC transporters: unifying concepts from high resolution structures
    • Hopfner K.P., Trainer J.A. Rad 50/SMC proteins and ABC transporters: unifying concepts from high resolution structures. Current Opinion in Structural Biology 2003, 13:249-255.
    • (2003) Current Opinion in Structural Biology , vol.13 , pp. 249-255
    • Hopfner, K.P.1    Trainer, J.A.2
  • 43
    • 84867883248 scopus 로고    scopus 로고
    • Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans
    • Jin M.S., Oldham M.L., Zhang Q., Chen J. Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans. Nature 2012, 490:566-569.
    • (2012) Nature , vol.490 , pp. 566-569
    • Jin, M.S.1    Oldham, M.L.2    Zhang, Q.3    Chen, J.4
  • 44
    • 84862223905 scopus 로고    scopus 로고
    • Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data
    • Martin J., Abubucker S., Heizer E., Taylor C.M., Mitreva M. Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data. Nucleic Acids Research 2012, 40(Database issue):D720-D728.
    • (2012) Nucleic Acids Research , vol.40 , Issue.DATABASE ISSUE
    • Martin, J.1    Abubucker, S.2    Heizer, E.3    Taylor, C.M.4    Mitreva, M.5
  • 45
    • 7444224600 scopus 로고    scopus 로고
    • Expression analysis of ABC transporters reveals differential functions of tandemly duplicated genes in Caenorhabditis elegans
    • Zhao Z., Sheps J.A., Ling V., Fang L.L., Baillie D.L. Expression analysis of ABC transporters reveals differential functions of tandemly duplicated genes in Caenorhabditis elegans. Journal of Molecular Biology 2004, 344:409-417.
    • (2004) Journal of Molecular Biology , vol.344 , pp. 409-417
    • Zhao, Z.1    Sheps, J.A.2    Ling, V.3    Fang, L.L.4    Baillie, D.L.5
  • 46
    • 34249037676 scopus 로고    scopus 로고
    • Comparative genomics and adaptive selection of the ATP-binding-cassette gene family in Caenorhabditis species
    • Zhao Z., Thomas J.H., Chen N., Sheps J.A., Baillie D.L. Comparative genomics and adaptive selection of the ATP-binding-cassette gene family in Caenorhabditis species. Genetics 2007, 175(3):1407-1418.
    • (2007) Genetics , vol.175 , Issue.3 , pp. 1407-1418
    • Zhao, Z.1    Thomas, J.H.2    Chen, N.3    Sheps, J.A.4    Baillie, D.L.5
  • 47
    • 79955538642 scopus 로고    scopus 로고
    • Anthelmintics are substrates and activators of nematode P-glycoprotein
    • Kerboeuf D., Guégnard F. Anthelmintics are substrates and activators of nematode P-glycoprotein. Antimicrobial Agents and Chemotherapy 2011, 55(5):2224-2232.
    • (2011) Antimicrobial Agents and Chemotherapy , vol.55 , Issue.5 , pp. 2224-2232
    • Kerboeuf, D.1    Guégnard, F.2
  • 49
    • 79958715150 scopus 로고    scopus 로고
    • Disruption of the ATP-binding cassette B7 (ABTM-1/ABCB7) induces oxidative stress and premature cell death in Caenorhabditis elegans
    • González-Cabo P., Bolinches-Amorós A., Cabello J., Ros S., Moreno S., Baylis H.A., et al. Disruption of the ATP-binding cassette B7 (ABTM-1/ABCB7) induces oxidative stress and premature cell death in Caenorhabditis elegans. Journal of Biological Chemistry 2011, 286(24):21304-21314.
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.24 , pp. 21304-21314
    • González-Cabo, P.1    Bolinches-Amorós, A.2    Cabello, J.3    Ros, S.4    Moreno, S.5    Baylis, H.A.6
  • 50
    • 77949694722 scopus 로고    scopus 로고
    • Detoxification of multiple heavy metals by a half-molecule ABC transporter, HMT-1, and coelomocytes of Caenorhabditis elegans
    • Schwartz M.S., Benci J.L., Selote D.S., Sharma A.K., Chen A.G., Dang H., et al. Detoxification of multiple heavy metals by a half-molecule ABC transporter, HMT-1, and coelomocytes of Caenorhabditis elegans. PLoS One 2010, 5(3):e9564.
    • (2010) PLoS One , vol.5 , Issue.3
    • Schwartz, M.S.1    Benci, J.L.2    Selote, D.S.3    Sharma, A.K.4    Chen, A.G.5    Dang, H.6
  • 51
    • 76849100919 scopus 로고    scopus 로고
    • The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC3767.7 in C. elegans
    • Haynes C.M., Yang Y., Blais S.P., Neubert T.A., Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC3767.7 in C. elegans. Molecular Cell 2010, 37(4):529-540.
    • (2010) Molecular Cell , vol.37 , Issue.4 , pp. 529-540
    • Haynes, C.M.1    Yang, Y.2    Blais, S.P.3    Neubert, T.A.4    Ron, D.5
  • 52
    • 67449162042 scopus 로고    scopus 로고
    • Normal function of a subset of intestinal granules in Caenorhabditis elegans requires ATP-binding cassette transporters HAF-4 and HAF-9, which are highly homologous to human lysosomal peptide transporter TAP-like
    • Kawai H., Tanji T., Shiraishi H., Yamada M., Iijima R., Inoue T., et al. Normal function of a subset of intestinal granules in Caenorhabditis elegans requires ATP-binding cassette transporters HAF-4 and HAF-9, which are highly homologous to human lysosomal peptide transporter TAP-like. Molecular Biology of the Cell 2009, 20(12):2979-2990.
    • (2009) Molecular Biology of the Cell , vol.20 , Issue.12 , pp. 2979-2990
    • Kawai, H.1    Tanji, T.2    Shiraishi, H.3    Yamada, M.4    Iijima, R.5    Inoue, T.6
  • 53
  • 54
    • 37249049742 scopus 로고    scopus 로고
    • Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiation
    • Currie E., King B., Lawrenson A.L., Schroeder L.K., Kershner A.M., Hermann G.J. Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiation. Genetics 2007, 177(3):1569-1582.
    • (2007) Genetics , vol.177 , Issue.3 , pp. 1569-1582
    • Currie, E.1    King, B.2    Lawrenson, A.L.3    Schroeder, L.K.4    Kershner, A.M.5    Hermann, G.J.6
  • 55
    • 34547743049 scopus 로고    scopus 로고
    • Two alternative mechanisms that regulate the presentation of apoptotic cell engulfment signal in Caenorhabditis elegans
    • Venegas V., Zhou Z. Two alternative mechanisms that regulate the presentation of apoptotic cell engulfment signal in Caenorhabditis elegans. Molecular Biology of the Cell 2007, 18(8):3180-3192.
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.8 , pp. 3180-3192
    • Venegas, V.1    Zhou, Z.2
  • 56
    • 0026618689 scopus 로고
    • The P-glycoprotein gene family of Caenorhabditis elegans. Cloning and characterization of genomic and complementary DNA sequences
    • Lincke C.R., The I., van Groenigen M., Borst P. The P-glycoprotein gene family of Caenorhabditis elegans. Cloning and characterization of genomic and complementary DNA sequences. Journal of Molecular Biology 1992, 228:701-711.
    • (1992) Journal of Molecular Biology , vol.228 , pp. 701-711
    • Lincke, C.R.1    The, I.2    van Groenigen, M.3    Borst, P.4
  • 57
    • 33947158693 scopus 로고    scopus 로고
    • Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle
    • Schroeder L.K., Kremer S., Kramer M.J., Currie E., Kwan E., Watts J.L., et al. Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Molecular Biology of the Cell 2007, 18(3):995-1008.
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.3 , pp. 995-1008
    • Schroeder, L.K.1    Kremer, S.2    Kramer, M.J.3    Currie, E.4    Kwan, E.5    Watts, J.L.6
  • 58
    • 27744446443 scopus 로고    scopus 로고
    • The ABC transporter PGP-2 from Caenorhabditis elegans is expressed in the sensory neuron pair AWA and contributes to lysosome formation and lipid storage within the intestine
    • Nunes F., Wolf M., hartmann J., Paul R.J. The ABC transporter PGP-2 from Caenorhabditis elegans is expressed in the sensory neuron pair AWA and contributes to lysosome formation and lipid storage within the intestine. Biochemical and Biophysical Research Communications 2005, 338(2):862-871.
    • (2005) Biochemical and Biophysical Research Communications , vol.338 , Issue.2 , pp. 862-871
    • Nunes, F.1    Wolf, M.2    Hartmann, J.3    Paul, R.J.4
  • 59
    • 33750429328 scopus 로고    scopus 로고
    • Suppression of the cup-5 mucolipidosis type IV-related lysosomal dysfunction by the inactivation of an ABC transporter in C. elegans
    • Schaheen L., Patton G., Fares H. Suppression of the cup-5 mucolipidosis type IV-related lysosomal dysfunction by the inactivation of an ABC transporter in C. elegans. Development 2006, 133(19):3939-3948.
    • (2006) Development , vol.133 , Issue.19 , pp. 3939-3948
    • Schaheen, L.1    Patton, G.2    Fares, H.3
  • 60
    • 23844539924 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein MRP-1 regulates dauer diapause by its export activity in Caenorhabditis elegans
    • Yabe T., Suzuki N., Furukawa T., Ishihara T., Katsura I. Multidrug resistance-associated protein MRP-1 regulates dauer diapause by its export activity in Caenorhabditis elegans. Development 2005, 132:3197-3207.
    • (2005) Development , vol.132 , pp. 3197-3207
    • Yabe, T.1    Suzuki, N.2    Furukawa, T.3    Ishihara, T.4    Katsura, I.5
  • 61
    • 3142630022 scopus 로고    scopus 로고
    • Identification of variant ABC transporter genes among Onchocerca volvulus collected from treated and untreated patients in Ghana, West Africa
    • Ardelli B.F., Prichard R.K. Identification of variant ABC transporter genes among Onchocerca volvulus collected from treated and untreated patients in Ghana, West Africa. Annals of Tropical Medicine and Parasitology 2004, 98:371-384.
    • (2004) Annals of Tropical Medicine and Parasitology , vol.98 , pp. 371-384
    • Ardelli, B.F.1    Prichard, R.K.2
  • 62
    • 35648951781 scopus 로고    scopus 로고
    • Reduced genetic polymorphism in an Onchocerca volvulus ABC transporter gene following treatment with ivermectin
    • Ardelli B.F., Prichard R.K. Reduced genetic polymorphism in an Onchocerca volvulus ABC transporter gene following treatment with ivermectin. Transactions of the Royal Society of Tropical Medicine and Hygiene 2007, 101:1223-1232.
    • (2007) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.101 , pp. 1223-1232
    • Ardelli, B.F.1    Prichard, R.K.2
  • 63
    • 22844449116 scopus 로고    scopus 로고
    • Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein
    • Ardelli B.F., Guerriero S.B., Prichard R.K. Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein. Molecular and Biochemical Parasitology 2005, 143:58-66.
    • (2005) Molecular and Biochemical Parasitology , vol.143 , pp. 58-66
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 64
    • 28044444352 scopus 로고    scopus 로고
    • Characterization of a half-size ATP binding cassette transporter gene which may be a useful marker for ivermectin selection in Onchocerca volvulus
    • Ardelli B.F., Guerriero S.B., Prichard R.K. Characterization of a half-size ATP binding cassette transporter gene which may be a useful marker for ivermectin selection in Onchocerca volvulus. Molecular and Biochemical Parasitology 2006, 145:94-100.
    • (2006) Molecular and Biochemical Parasitology , vol.145 , pp. 94-100
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 65
    • 80052416428 scopus 로고    scopus 로고
    • Ivermectin imposes selection pressure on P-glycoprotein from Onchocerca volvulus: linkage disequilibrium and genotype diversity
    • Ardelli B.F., Guerriero S.B., Prichard R.K. Ivermectin imposes selection pressure on P-glycoprotein from Onchocerca volvulus: linkage disequilibrium and genotype diversity. Parasitology 2006, 11:1-12.
    • (2006) Parasitology , vol.11 , pp. 1-12
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 66
    • 70349574862 scopus 로고    scopus 로고
    • P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus
    • Bartley D.J., McAllister H., Bartley Y., Dupuy J., Menez C., Alvinerie M., et al. P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus. Parasitology 2009, 136:1081-1088.
    • (2009) Parasitology , vol.136 , pp. 1081-1088
    • Bartley, D.J.1    McAllister, H.2    Bartley, Y.3    Dupuy, J.4    Menez, C.5    Alvinerie, M.6
  • 67
    • 0032531334 scopus 로고    scopus 로고
    • Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus
    • Blackhall W.J., Liu H.Y., Xu M., Prichard R.K., Beech R.N. Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus. Molecular and Biochemical Parasitology 1998, 95:193-201.
    • (1998) Molecular and Biochemical Parasitology , vol.95 , pp. 193-201
    • Blackhall, W.J.1    Liu, H.Y.2    Xu, M.3    Prichard, R.K.4    Beech, R.N.5
  • 69
    • 20644432213 scopus 로고    scopus 로고
    • A comparison of genetic polymorphism in populations of Onchocerca volvulus from untreated- and ivermectin-treated patients
    • Eng J.K., Prichard R.K. A comparison of genetic polymorphism in populations of Onchocerca volvulus from untreated- and ivermectin-treated patients. Molecular and Biochemical Parasitology 2005, 142(2):193-202.
    • (2005) Molecular and Biochemical Parasitology , vol.142 , Issue.2 , pp. 193-202
    • Eng, J.K.1    Prichard, R.K.2
  • 70
    • 0032753556 scopus 로고    scopus 로고
    • Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus)
    • Molento M.B., Prichard R.K. Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus). Parasitology Research 1999, 85:1007-1011.
    • (1999) Parasitology Research , vol.85 , pp. 1007-1011
    • Molento, M.B.1    Prichard, R.K.2
  • 71
    • 0036801051 scopus 로고    scopus 로고
    • Immunocompetence may be important in the effectiveness of Mectizan (ivermectin) in the treatment of human onchocerciasis
    • Ali M.M., Mukhtar M.M., Baraka O.Z., Homeida M.M., Kheir M.M., Mackenzie C.D. Immunocompetence may be important in the effectiveness of Mectizan (ivermectin) in the treatment of human onchocerciasis. Acta Tropica 2002, 84:49-53.
    • (2002) Acta Tropica , vol.84 , pp. 49-53
    • Ali, M.M.1    Mukhtar, M.M.2    Baraka, O.Z.3    Homeida, M.M.4    Kheir, M.M.5    Mackenzie, C.D.6
  • 73
    • 38749105426 scopus 로고    scopus 로고
    • P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles
    • Blackhall W.J., Prichard R.K., Beech R.N. P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles. Veterinary Parasitology 2008, 152(1-2):101-107.
    • (2008) Veterinary Parasitology , vol.152 , Issue.1-2 , pp. 101-107
    • Blackhall, W.J.1    Prichard, R.K.2    Beech, R.N.3
  • 74
    • 0033486171 scopus 로고    scopus 로고
    • A hybridization technique to identify anthelmintic resistance genes in Haemonchus
    • Le Jambre L.F., Lenane I.J., Wardrop A.J. A hybridization technique to identify anthelmintic resistance genes in Haemonchus. International Journal of Parasitology 1999, 29(12):1979-1985.
    • (1999) International Journal of Parasitology , vol.29 , Issue.12 , pp. 1979-1985
    • Le Jambre, L.F.1    Lenane, I.J.2    Wardrop, A.J.3
  • 75
    • 79960556216 scopus 로고    scopus 로고
    • Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta
    • Dicker A.J., Nisbet A.J., Skuce P.J. Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta. International Journal of Parasitology 2011, 41(9):935-942.
    • (2011) International Journal of Parasitology , vol.41 , Issue.9 , pp. 935-942
    • Dicker, A.J.1    Nisbet, A.J.2    Skuce, P.J.3
  • 77
    • 0033214947 scopus 로고    scopus 로고
    • Cystic canal mutants in Caenorhabditis elegans are defective in the apical membrane domain of the renal (excretory) cell
    • Buechner M., Hall D.H., Bhatt H., Hedgecock E.M. Cystic canal mutants in Caenorhabditis elegans are defective in the apical membrane domain of the renal (excretory) cell. Developmental Biology 1999, 214:227-241.
    • (1999) Developmental Biology , vol.214 , pp. 227-241
    • Buechner, M.1    Hall, D.H.2    Bhatt, H.3    Hedgecock, E.M.4
  • 78
    • 80054694509 scopus 로고    scopus 로고
    • Candidate anthelmintic resistance-associated gene expression and sequence polymorphism in a triple-resistant field isolate of Haemonchus contortus
    • Williamson S.M., Storey B., Howell S., Harper K.M., Kaplan R.M., Wolstenholme A.J. Candidate anthelmintic resistance-associated gene expression and sequence polymorphism in a triple-resistant field isolate of Haemonchus contortus. Molecular and Biochemical Parasitology 2011, 180(2):99-105.
    • (2011) Molecular and Biochemical Parasitology , vol.180 , Issue.2 , pp. 99-105
    • Williamson, S.M.1    Storey, B.2    Howell, S.3    Harper, K.M.4    Kaplan, R.M.5    Wolstenholme, A.J.6
  • 79
    • 0032789210 scopus 로고    scopus 로고
    • Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoprotein
    • Sangster N.C., Bannan S.C., Weiss A.S., Nulf S.C., Klein R.D., Geary T.G. Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoprotein. Experimental Parasitology 1999, 91(3):250-257.
    • (1999) Experimental Parasitology , vol.91 , Issue.3 , pp. 250-257
    • Sangster, N.C.1    Bannan, S.C.2    Weiss, A.S.3    Nulf, S.C.4    Klein, R.D.5    Geary, T.G.6
  • 80
    • 0032790754 scopus 로고    scopus 로고
    • Identification and stage specific-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus
    • Huang Y.J., Prichard R.K. Identification and stage specific-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus. Molecular and Biochemical Parasitology 1999, 102:273-281.
    • (1999) Molecular and Biochemical Parasitology , vol.102 , pp. 273-281
    • Huang, Y.J.1    Prichard, R.K.2
  • 81
    • 0028229150 scopus 로고
    • Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
    • Schinkel A.H., Smit J.J.M., van Tellingen O., Beiinen J.H., Wagenarr E., van Deemter L., et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 1994, 77:491-502.
    • (1994) Cell , vol.77 , pp. 491-502
    • Schinkel, A.H.1    Smit, J.J.M.2    van Tellingen, O.3    Beiinen, J.H.4    Wagenarr, E.5    van Deemter, L.6
  • 82
    • 0029910521 scopus 로고    scopus 로고
    • Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans
    • Broeks A., Gerrard B., Allikmets R., Dean M., Plasterak R.H. Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans. EMBO Journal 1996, 15:6132-6143.
    • (1996) EMBO Journal , vol.15 , pp. 6132-6143
    • Broeks, A.1    Gerrard, B.2    Allikmets, R.3    Dean, M.4    Plasterak, R.H.5
  • 83
    • 0028988540 scopus 로고
    • A P-glycoprotein protects Caenorhabditis elegans against natural toxins
    • Broeks A., Janssen H.W., Calafat J., Plasterak R.H. A P-glycoprotein protects Caenorhabditis elegans against natural toxins. EMBO Journal 1995, 14:1858-1866.
    • (1995) EMBO Journal , vol.14 , pp. 1858-1866
    • Broeks, A.1    Janssen, H.W.2    Calafat, J.3    Plasterak, R.H.4
  • 84
    • 4644269603 scopus 로고    scopus 로고
    • Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy
    • Summers M.A., Moore J.L., McAuley J.W. Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy. The Annals of Pharmacotherapy 2004, 38:1631-1634.
    • (2004) The Annals of Pharmacotherapy , vol.38 , pp. 1631-1634
    • Summers, M.A.1    Moore, J.L.2    McAuley, J.W.3
  • 85
    • 77956012325 scopus 로고    scopus 로고
    • Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep
    • Lifschitz A., Entrocasso C., Alvarez L., Lloberas M., Ballent M., Manazza G., et al. Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep. Veterinary Parasitology 2010, 172(304):291-298.
    • (2010) Veterinary Parasitology , vol.172 , Issue.304 , pp. 291-298
    • Lifschitz, A.1    Entrocasso, C.2    Alvarez, L.3    Lloberas, M.4    Ballent, M.5    Manazza, G.6
  • 86
    • 0036038983 scopus 로고    scopus 로고
    • Analysis and partial reversal of multidrug resistance to anthelmintics due to P-glycoprotein in Haemonchus contortus eggs using Lens culinaris lectin
    • Kerboeuf D., Guégnard F., La Vern Y. Analysis and partial reversal of multidrug resistance to anthelmintics due to P-glycoprotein in Haemonchus contortus eggs using Lens culinaris lectin. Parasitology Research 2002, 88(9):816-821.
    • (2002) Parasitology Research , vol.88 , Issue.9 , pp. 816-821
    • Kerboeuf, D.1    Guégnard, F.2    La Vern, Y.3
  • 87
    • 0032948271 scopus 로고    scopus 로고
    • Flow cytometry analysis of drug transport mechanisms in Haemonchus contortus susceptible or resistant to anthelmintics
    • Kerboeuf D., Chambrier P., Le Vern Y., Aycardi J. Flow cytometry analysis of drug transport mechanisms in Haemonchus contortus susceptible or resistant to anthelmintics. Parasitology Research 1999, 85(2):118-123.
    • (1999) Parasitology Research , vol.85 , Issue.2 , pp. 118-123
    • Kerboeuf, D.1    Chambrier, P.2    Le Vern, Y.3    Aycardi, J.4
  • 88
    • 84862500665 scopus 로고    scopus 로고
    • Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate
    • Bartley D.J., Morrison A.A., Dupuy J., Bartley Y., Sutra J.F., Menez C., et al. Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate. Veterinary Parasitology 2012, 187(3-4):464-472.
    • (2012) Veterinary Parasitology , vol.187 , Issue.3-4 , pp. 464-472
    • Bartley, D.J.1    Morrison, A.A.2    Dupuy, J.3    Bartley, Y.4    Sutra, J.F.5    Menez, C.6
  • 89
    • 79957587290 scopus 로고    scopus 로고
    • Triterpenoid saponins affect the function of P-glycoprotein and reduce the survival of the free-living stages of Heligmosomoides bakeri
    • Doligalska M., Jóźwicka K., Kiersnowska M., Mroczek A., Paczkowski C., Janiszowska W. Triterpenoid saponins affect the function of P-glycoprotein and reduce the survival of the free-living stages of Heligmosomoides bakeri. Veterinary Parasitology 2011, 179(1-3):144-151.
    • (2011) Veterinary Parasitology , vol.179 , Issue.1-3 , pp. 144-151
    • Doligalska, M.1    Jóźwicka, K.2    Kiersnowska, M.3    Mroczek, A.4    Paczkowski, C.5    Janiszowska, W.6
  • 90
    • 84860535245 scopus 로고    scopus 로고
    • Three decades of P-gp inhibitors: skimming through several generations and scaffolds
    • Palmiera A., Sousa E., Vasconcelos M.H., Pinto M.M. Three decades of P-gp inhibitors: skimming through several generations and scaffolds. Current Medicinal Chemistry 2012, 19(13):1946-2025.
    • (2012) Current Medicinal Chemistry , vol.19 , Issue.13 , pp. 1946-2025
    • Palmiera, A.1    Sousa, E.2    Vasconcelos, M.H.3    Pinto, M.M.4
  • 92
    • 0742269421 scopus 로고    scopus 로고
    • Impact of genetic polymorphisms in transmembrane carrier-systems on drug an xenobiotic distribution
    • Gerloff T. Impact of genetic polymorphisms in transmembrane carrier-systems on drug an xenobiotic distribution. Archives of Pharmacology 2004, 369:69-77.
    • (2004) Archives of Pharmacology , vol.369 , pp. 69-77
    • Gerloff, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.