메뉴 건너뛰기




Volumn 136, Issue 9, 2009, Pages 1081-1088

P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus

Author keywords

ABC transporters; Anthelmintic resistance; Haemonchus contortus; Ivermectin; P glycoprotein; Teladorsagia circumcincta

Indexed keywords

GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; IVERMECTIN; KETOCONAZOLE; PLURONIC P85; QUERCETIN; UNCLASSIFIED DRUG; VALSPODAR; VERAPAMIL; ANTHELMINTIC AGENT;

EID: 70349574862     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182009990345     Document Type: Article
Times cited : (86)

References (64)
  • 2
    • 33344474213 scopus 로고    scopus 로고
    • Modulation of the P-glycoproteinmediated intestinal secretion of ivermectin: In vitro and in vivo assessments
    • Ballent, M., Lifschitz, A., Virkel, G., Sallovitz, J. and Lanusse, C. (2006). Modulation of the P-glycoproteinmediated intestinal secretion of ivermectin: in vitro and in vivo assessments. Drug Metabolism and Disposition 34, 457-463.
    • (2006) Drug Metabolism and Disposition , vol.34 , pp. 457-463
    • Ballent, M.1    Lifschitz, A.2    Virkel, G.3    Sallovitz, J.4    Lanusse, C.5
  • 4
    • 28044441364 scopus 로고    scopus 로고
    • Further characterisation of a triple resistant field isolate of Teladorsagia from a Scottish lowland sheep farm
    • Bartley, D. J., Jackson, E., Sargison, N. and Jackson, F. (2005). Further characterisation of a triple resistant field isolate of Teladorsagia from a Scottish lowland sheep farm. Veterinary Parasitology 134, 261-266.
    • (2005) Veterinary Parasitology , vol.134 , pp. 261-266
    • Bartley, D.J.1    Jackson, E.2    Sargison, N.3    Jackson, F.4
  • 6
    • 0029809394 scopus 로고    scopus 로고
    • Interaction between fenbendazole and piperonyl butoxide: Pharmacokinetic and pharmacodynamic implications
    • Benchaoui, H. A. and McKellar, Q. A. (1996). Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications. Journal of Pharmacy and Pharmacology 48, 753-759.
    • (1996) Journal of Pharmacy and Pharmacology , vol.48 , pp. 753-759
    • Benchaoui, H.A.1    McKellar, Q.A.2
  • 7
    • 0030831635 scopus 로고    scopus 로고
    • Partial in vitro reversal of benzimidazole resistance by the free-living stages of Haemonchus contortus with verapamil
    • Beugnet, F., Gauthey, M. and Kerboeuf, D. (1997). Partial in vitro reversal of benzimidazole resistance by the free-living stages of Haemonchus contortus with verapamil. Veterinary Record 141, 575-576.
    • (1997) Veterinary Record , vol.141 , pp. 575-576
    • Beugnet, F.1    Gauthey, M.2    Kerboeuf, D.3
  • 8
    • 0032531334 scopus 로고    scopus 로고
    • Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus
    • Blackhall, W. J., Liu, H. Y., Xu ,M., Prichard, R. K. and Beech, R. N. (1998). Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus. Molecular and Biochemical Parasitology 95, 193-201.
    • (1998) Molecular and Biochemical Parasitology , vol.95 , pp. 193-201
    • Blackhall, W.J.1    Liu, H.Y.2    Xu, M.3    Prichard, R.K.4    Beech, R.N.5
  • 9
    • 0023340708 scopus 로고
    • Changes in LC50 in an in vitro egg development assay during the patent period of Haemonchus contortus in sheep
    • Borgsteede, F. H. and Couwenberg, T. (1987). Changes in LC50 in an in vitro egg development assay during the patent period of Haemonchus contortus in sheep. Research in Veterinary Science 42, 413-414.
    • (1987) Research in Veterinary Science , vol.42 , pp. 413-414
    • Borgsteede, F.H.1    Couwenberg, T.2
  • 11
    • 0028988540 scopus 로고
    • A P-glycoprotein protects Caenorhabditis elegans against natural toxins
    • Broeks, A., Janssen, H. W., Calafat, J. and Plasterk, R. H. (1995). A P-glycoprotein protects Caenorhabditis elegans against natural toxins. The EMBO Journal 14, 1858-1866.
    • (1995) The EMBO Journal , vol.14 , pp. 1858-1866
    • Broeks, A.1    Janssen, H.W.2    Calafat, J.3    Plasterk, R.H.4
  • 12
    • 0029966747 scopus 로고    scopus 로고
    • The abamectin derivative ivermectin is a potent P-glycoprotein inhibitor
    • Didier, A. and Loor, F. (1996). The abamectin derivative ivermectin is a potent P-glycoprotein inhibitor. Anticancer Drugs 7, 745-751.
    • (1996) Anticancer Drugs , vol.7 , pp. 745-751
    • Didier, A.1    Loor, F.2
  • 13
    • 0037465616 scopus 로고    scopus 로고
    • Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: Quercetin
    • Dupuy, J., Larrieu, G., Sutra, J. F., Lespine, A. and Alvinerie, M. (2003). Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin. Veterinary Parasitololgy 112, 337-347.
    • (2003) Veterinary Parasitololgy , vol.112 , pp. 337-347
    • Dupuy, J.1    Larrieu, G.2    Sutra, J.F.3    Lespine, A.4    Alvinerie, M.5
  • 14
    • 0037413374 scopus 로고    scopus 로고
    • Amphidial structure of ivermectin-resistant and susceptible laboratory and field strains of Haemonchus contortus
    • Freeman, A. S., Nghiem, C., Li, J., Ashton, F. T., Guerrero, J., Shoop, W. L. and Schad, G. A. (2003). Amphidial structure of ivermectin-resistant and susceptible laboratory and field strains of Haemonchus contortus. Veterinary Parasitololgy 110, 217-226.
    • (2003) Veterinary Parasitololgy , vol.110 , pp. 217-226
    • Freeman, A.S.1    Nghiem, C.2    Li, J.3    Ashton, F.T.4    Guerrero, J.5    Shoop, W.L.6    Schad, G.A.7
  • 16
    • 26844575149 scopus 로고    scopus 로고
    • Ivermectin 20 years on: Maturation of a wonder drug
    • Geary, T. G. (2005). Ivermectin 20 years on: maturation of a wonder drug. Trends in Parasitology 21, 530-532.
    • (2005) Trends in Parasitology , vol.21 , pp. 530-532
    • Geary, T.G.1
  • 17
    • 0028958746 scopus 로고
    • Avermectin inhibition of larval development in Haemonchus contortus - Effects of ivermectin resistance
    • Gill, J. H., Redwin, J. M., van Wyk, J. A. and Lacey, E. (1995). Avermectin inhibition of larval development in Haemonchus contortus - effects of ivermectin resistance. International Journal for Parasitology 25, 463-470.
    • (1995) International Journal for Parasitology , vol.25 , pp. 463-470
    • Gill, J.H.1    Redwin, J.M.2    Van Wyk, J.A.3    Lacey, E.4
  • 18
    • 0031803119 scopus 로고    scopus 로고
    • Evidence of multiple mechanisms of avermectin resistance in Haemonchus contortus - Comparison of selection protocols
    • Gill, J. H., Kerr, C. A., Shoop, W. L. and Lacey, E. (1998). Evidence of multiple mechanisms of avermectin resistance in Haemonchus contortus - comparison of selection protocols. International Journal for Parasitology 28, 783-789.
    • (1998) International Journal for Parasitology , vol.28 , pp. 783-789
    • Gill, J.H.1    Kerr, C.A.2    Shoop, W.L.3    Lacey, E.4
  • 19
    • 0031834886 scopus 로고    scopus 로고
    • Avermectin/milbemycin resistance in trichostrongyloid nematodes
    • Gill, J. H. and Lacey, E. (1998). Avermectin/milbemycin resistance in trichostrongyloid nematodes. International Journal for Parasitology 28, 863-877.
    • (1998) International Journal for Parasitology , vol.28 , pp. 863-877
    • Gill, J.H.1    Lacey, E.2
  • 20
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. M. and Pastan, I. (1993). Biochemistry of multidrug resistance mediated by the multidrug transporter. Annual Review of Biochemistry 62, 385-427.
    • (1993) Annual Review of Biochemistry , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 21
    • 4844225150 scopus 로고    scopus 로고
    • Amphids: The neuronal ultrastructure of macrocyclic-lactone-resistant Haemonchus contortus
    • Guerrero, J. and Freeman, A. S. (2004). Amphids: the neuronal ultrastructure of macrocyclic-lactone-resistant Haemonchus contortus. Parasitologia 46, 237-240.
    • (2004) Parasitologia , vol.46 , pp. 237-240
    • Guerrero, J.1    Freeman, A.S.2
  • 22
    • 0037032676 scopus 로고    scopus 로고
    • Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats
    • Hsiu, S. L., Hou, Y. C., Wang, Y. H., Tsao, C. W., Su, S. F. and Chao, P. D. (2002). Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats. Life Sciences 72, 227-235.
    • (2002) Life Sciences , vol.72 , pp. 227-235
    • Hsiu, S.L.1    Hou, Y.C.2    Wang, Y.H.3    Tsao, C.W.4    Su, S.F.5    Chao, P.D.6
  • 25
    • 0034110796 scopus 로고    scopus 로고
    • The development of anthelmintic resistance in sheep nematodes
    • Jackson, F. and Coop, R. L. (2000). The development of anthelmintic resistance in sheep nematodes. Parasitology 120 (Suppl.), S95-S107.
    • (2000) Parasitology , vol.120 , Issue.SUPPL.
    • Jackson, F.1    Coop, R.L.2
  • 26
    • 57649087686 scopus 로고    scopus 로고
    • Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans
    • James, C. E. and Davey, M. W. (2009). Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans. International Journal for Parasitology 39, 213-220.
    • (2009) International Journal for Parasitology , vol.39 , pp. 213-220
    • James, C.E.1    Davey, M.W.2
  • 28
    • 4444375921 scopus 로고    scopus 로고
    • Drug resistance in nematodes of veterinary importance: A status report
    • Kaplan, R. M. (2004). Drug resistance in nematodes of veterinary importance: a status report. Trends in Parasitology 20, 477-481.
    • (2004) Trends in Parasitology , vol.20 , pp. 477-481
    • Kaplan, R.M.1
  • 29
    • 0024970193 scopus 로고
    • Haemonchus contortus: Infectivity and resistance to benzimidazoles
    • Kerboeuf, D., Hubert, J. and Mallet, S. (1989). Haemonchus contortus: infectivity and resistance to benzimidazoles. Veterinary Record 124, 399-400.
    • (1989) Veterinary Record , vol.124 , pp. 399-400
    • Kerboeuf, D.1    Hubert, J.2    Mallet, S.3
  • 30
    • 0036038983 scopus 로고    scopus 로고
    • Analysis and partial reversal of multidrug resistance to anthelmintics due to P-glycoprotein in Haemonchus contortus eggs using Lens culinaris lectin
    • Kerboeuf, D., Guegnard, F. and Le Vern, Y. (2002). Analysis and partial reversal of multidrug resistance to anthelmintics due to P-glycoprotein in Haemonchus contortus eggs using Lens culinaris lectin. Parasitology Research 88, 816-821.
    • (2002) Parasitology Research , vol.88 , pp. 816-821
    • Kerboeuf, D.1    Guegnard, F.2    Le Vern, Y.3
  • 32
    • 0031843251 scopus 로고    scopus 로고
    • Effects of macrocyclic lactones on ingestion in susceptible and resistant Haemonchus contortus larvae
    • Kotze, A. C. (1998). effects of macrocyclic lactones on ingestion in susceptible and resistant Haemonchus contortus larvae. Journal of Parasitology 84, 631-635.
    • (1998) Journal of Parasitology , vol.84 , pp. 631-635
    • Kotze, A.C.1
  • 33
    • 0037179485 scopus 로고    scopus 로고
    • High-level ivermectin resistance in a field isolate of Haemonchus contortus associated with a low level of resistance in the larval stage: Implications for resistance detection
    • Kotze, A. C., Dobson, R. J., Tyrrell, K. L. and Stein, P. A. (2002). High-level ivermectin resistance in a field isolate of Haemonchus contortus associated with a low level of resistance in the larval stage: implications for resistance detection. Veterinary Parasitology 108, 255-263.
    • (2002) Veterinary Parasitology , vol.108 , pp. 255-263
    • Kotze, A.C.1    Dobson, R.J.2    Tyrrell, K.L.3    Stein, P.A.4
  • 34
    • 0027162531 scopus 로고
    • Clinical pharmacokinetics and metabolism of benzimidazole anthelmintics in ruminants
    • Lanusse, C. E. and Prichard, R. K. (1993). Clinical pharmacokinetics and metabolism of benzimidazole anthelmintics in ruminants. Drug Metabolism Reviews 25, 235-279.
    • (1993) Drug Metabolism Reviews , vol.25 , pp. 235-279
    • Lanusse, C.E.1    Prichard, R.K.2
  • 35
    • 0029821995 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the multidrug resistance protein (MRP) gene
    • Lautier, D., Canitrot, Y., Deeley, R. G. and Cole, S. P. (1996). Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochemical Pharmacology 52, 967-977.
    • (1996) Biochemical Pharmacology , vol.52 , pp. 967-977
    • Lautier, D.1    Canitrot, Y.2    Deeley, R.G.3    Cole, S.P.4
  • 36
  • 40
    • 45449101104 scopus 로고    scopus 로고
    • ABC transporter modulation: A strategy to enhance the activity of macrocyclic lactone anthelmintics
    • Lespine, A., Alvinerie, M., Vercruysse, J., Prichard, R. K. and Geldhof, P. (2008). ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics. Trends in Parasitology 24, 293-298.
    • (2008) Trends in Parasitology , vol.24 , pp. 293-298
    • Lespine, A.1    Alvinerie, M.2    Vercruysse, J.3    Prichard, R.K.4    Geldhof, P.5
  • 43
    • 0032753556 scopus 로고    scopus 로고
    • Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the effcacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus)
    • Molento, M. B. and Prichard, R. K. (1999). effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the effcacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus). Parasitology Research 85, 1007-1011.
    • (1999) Parasitology Research , vol.85 , pp. 1007-1011
    • Molento, M.B.1    Prichard, R.K.2
  • 44
    • 0442298029 scopus 로고    scopus 로고
    • Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep
    • Molento, M. B., Lifschitz, A., Sallovitz, J., Lanusse, C. and Prichard, R. (2004). influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep. Parasitology Research 92, 121-127.
    • (2004) Parasitology Research , vol.92 , pp. 121-127
    • Molento, M.B.1    Lifschitz, A.2    Sallovitz, J.3    Lanusse, C.4    Prichard, R.5
  • 45
    • 26044454086 scopus 로고    scopus 로고
    • Is anthelmintic resistance a concern for heartworm control? What can we learn from the human filariasis control programs?
    • Prichard, R. K. (2005). Is anthelmintic resistance a concern for heartworm control? What can we learn from the human filariasis control programs? Veterinary Parasitology 133, 243-253.
    • (2005) Veterinary Parasitology , vol.133 , pp. 243-253
    • Prichard, R.K.1
  • 46
    • 35448972959 scopus 로고    scopus 로고
    • Ivermectin resistance and overview of the consortium for anthelmintic resistance SNPs
    • Prichard, R. K. (2007). Ivermectin resistance and overview of the consortium for anthelmintic resistance SNPs. Expert Opinion on Drug Discovery 2, S41-S52.
    • (2007) Expert Opinion on Drug Discovery , vol.2
    • Prichard, R.K.1
  • 47
    • 34347399591 scopus 로고    scopus 로고
    • ABC transporters and beta-tubulin in macrocyclic lactone resistance: Prospects for marker development
    • Prichard, R. K. and Roulet, A. (2007). ABC transporters and beta-tubulin in macrocyclic lactone resistance: prospects for marker development. Parasitology 134, 1123-1132.
    • (2007) Parasitology , vol.134 , pp. 1123-1132
    • Prichard, R.K.1    Roulet, A.2
  • 48
    • 0030901902 scopus 로고    scopus 로고
    • Haemonchus contortus: The uptake and metabolism of closantel
    • Rothwell, J. and Sangster, N. (1997). Haemonchus contortus: the uptake and metabolism of closantel. International Journal for Parasitology 27, 313-319.
    • (1997) International Journal for Parasitology , vol.27 , pp. 313-319
    • Rothwell, J.1    Sangster, N.2
  • 49
    • 0030517172 scopus 로고    scopus 로고
    • Pharmacology of anthelmintic resistance
    • Sangster, N. (1996). Pharmacology of anthelmintic resistance. Parasitology 113 (Suppl.), S201-S216.
    • (1996) Parasitology , vol.113 , Issue.SUPPL.
    • Sangster, N.1
  • 50
    • 0032789210 scopus 로고    scopus 로고
    • Haemonchus contortus: Sequence heterogeneity of internucleotide binding domains from P-glycoproteins
    • Sangster, N. C., Bannan, S. C., Weiss, A. S., Nulf, S. C., Klein, R. D. and Geary, T. G. (1999). Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins. Experimental Parasitology 91, 250-257.
    • (1999) Experimental Parasitology , vol.91 , pp. 250-257
    • Sangster, N.C.1    Bannan, S.C.2    Weiss, A.S.3    Nulf, S.C.4    Klein, R.D.5    Geary, T.G.6
  • 51
    • 33645565580 scopus 로고    scopus 로고
    • Resistance as a tool for discovering and understanding targets in parasite neuromusculature
    • Sangster, N. C., Song, J. and Demeler, J. (2005). Resistance as a tool for discovering and understanding targets in parasite neuromusculature. Parasitology 131 (Suppl.), S179-S190.
    • (2005) Parasitology , vol.131 , Issue.SUPPL.
    • Sangster, N.C.1    Song, J.2    Demeler, J.3
  • 53
    • 0002529726 scopus 로고
    • Cross-resistance to the biological insecticide abamectin in pyrethroid-resistant house flies
    • Scott, J. G. (1989). Cross-resistance to the biological insecticide abamectin in pyrethroid-resistant house flies. Pesticide Biochemistry and Physiology 34, 27-31.
    • (1989) Pesticide Biochemistry and Physiology , vol.34 , pp. 27-31
    • Scott, J.G.1
  • 55
    • 0036855152 scopus 로고    scopus 로고
    • Effects of macrocyclic lactone anthelmintics on feeding and pharyngeal pumping in Trichostrongylus colubriformis in vitro
    • Sheri, J. C., Kotze, A. C., Sangster, N. C. and Martin, R. J. (2002). effects of macrocyclic lactone anthelmintics on feeding and pharyngeal pumping in Trichostrongylus colubriformis in vitro. Parasitology 125, 477-484.
    • (2002) Parasitology , vol.125 , pp. 477-484
    • Sheri, J.C.1    Kotze, A.C.2    Sangster, N.C.3    Martin, R.J.4
  • 56
    • 0027359591 scopus 로고
    • Mutual resistance to avermectins and milbemycins: Oral activity of ivermectin and moxidectin against ivermectin-resistant and susceptible nematodes
    • Shoop, W. L., Haines, H. W., Michael, B. F. and Eary, C. H. (1993). Mutual resistance to avermectins and milbemycins: oral activity of ivermectin and moxidectin against ivermectin-resistant and susceptible nematodes. Veterinary Record 133, 445-447.
    • (1993) Veterinary Record , vol.133 , pp. 445-447
    • Shoop, W.L.1    Haines, H.W.2    Michael, B.F.3    Eary, C.H.4
  • 57
    • 0042967679 scopus 로고    scopus 로고
    • Resistance to prophylactic treatment with macrocyclic lactone anthelmintics in Teladorsagia circumcincta
    • Sutherland, I. A., Brown, A. E., Leathwick, D. M. and Bisset, S. A. (2003). Resistance to prophylactic treatment with macrocyclic lactone anthelmintics in Teladorsagia circumcincta. Veterinary Parasitology 115, 301-309.
    • (2003) Veterinary Parasitology , vol.115 , pp. 301-309
    • Sutherland, I.A.1    Brown, A.E.2    Leathwick, D.M.3    Bisset, S.A.4
  • 60
    • 33244491263 scopus 로고    scopus 로고
    • Molecular diagnosis of anthelmintic resistance
    • von Samson-Himmelstjerna, G. (2006). Molecular diagnosis of anthelmintic resistance. Veterinary Parasitology 136, 99-107.
    • (2006) Veterinary Parasitology , vol.136 , pp. 99-107
    • Von Samson-Himmelstjerna, G.1
  • 61
    • 0842347428 scopus 로고    scopus 로고
    • Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey
    • Ward, K. W., Stelman, G. J., Morgan, J. A., Zeigler, K. S., Azzarano, L. M., Kehler, J. R., McSurdy- Freed, J. E., Proksch, J. W. and Smith, B. R. (2004). Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey. Drug Metabolism and Disposition 32, 172-177.
    • (2004) Drug Metabolism and Disposition , vol.32 , pp. 172-177
    • Ward, K.W.1    Stelman, G.J.2    Morgan, J.A.3    Zeigler, K.S.4    Azzarano, L.M.5    Kehler, J.R.6    McSurdy- Freed, J.E.7    Proksch, J.W.8    Smith, B.R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.