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Volumn 90, Issue 1, 1998, Pages 135-141

Plasmodium and Leishmania: The role of mdr genes in mediating drug resistance

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; CHLOROQUINE; VINBLASTINE;

EID: 0031751905     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1998.4311     Document Type: Article
Times cited : (23)

References (56)
  • 1
    • 0026645269 scopus 로고
    • Selection for high level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
    • Barnes, D. A., Foote, S. J., Galatis, D., Kemp, D. J., and Cowman, A. F. 1992. Selection for high level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. EMBO Journal 11, 3067-3075.
    • (1992) EMBO Journal , vol.11 , pp. 3067-3075
    • Barnes, D.A.1    Foote, S.J.2    Galatis, D.3    Kemp, D.J.4    Cowman, A.F.5
  • 2
    • 0029586497 scopus 로고
    • Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from subsaharan Africa
    • Basco, L. K., Le Bras, J., Rhoades, Z., and Wilson, C. M. 1995. Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from subsaharan Africa. Molecular and Biochemical Parasitology 74, 157-166.
    • (1995) Molecular and Biochemical Parasitology , vol.74 , pp. 157-166
    • Basco, L.K.1    Le Bras, J.2    Rhoades, Z.3    Wilson, C.M.4
  • 4
    • 0030592439 scopus 로고    scopus 로고
    • Cloning and sequence analysis of a novel member of the ATP-binding cassette (ABC) protein gene family from Plasmodium falciparum
    • Bozdech, Z., Delling, U., Volkman, S. K., Cowman, A. F., and Schurr, E. 1996. Cloning and sequence analysis of a novel member of the ATP-binding cassette (ABC) protein gene family from Plasmodium falciparum. Molecular and Biochemical Parasitology 81, 41-51.
    • (1996) Molecular and Biochemical Parasitology , vol.81 , pp. 41-51
    • Bozdech, Z.1    Delling, U.2    Volkman, S.K.3    Cowman, A.F.4    Schurr, E.5
  • 5
    • 0025945313 scopus 로고
    • Heavy metal resistance: A new role for P-glycoproteins in Leishmania
    • Callahan, H. L., and Beverley, S. M. 1991. Heavy metal resistance: A new role for P-glycoproteins in Leishmania. Journal of Biological Chemistry 266, 18427-18430.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 18427-18430
    • Callahan, H.L.1    Beverley, S.M.2
  • 6
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
    • Chen, C. J., Chin, J. E., Ueda, K., Clark, D. P., Pastan, I., Gottesman, M. M., and Roninson, I. B. 1986. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 47, 381-389.
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen, C.J.1    Chin, J.E.2    Ueda, K.3    Clark, D.P.4    Pastan, I.5    Gottesman, M.M.6    Roninson, I.B.7
  • 7
    • 0027178549 scopus 로고
    • Cloning and functional analysis of an extrachromosomally amplified multi-drug resistance-like gene in Leishmania enriettii
    • Chow, L. M., Wong, A. K., Ullman, B., and Wirth, D. F. 1993. Cloning and functional analysis of an extrachromosomally amplified multi-drug resistance-like gene in Leishmania enriettii. Molecular and Biochemical Parasitology 60, 195-208.
    • (1993) Molecular and Biochemical Parasitology , vol.60 , pp. 195-208
    • Chow, L.M.1    Wong, A.K.2    Ullman, B.3    Wirth, D.F.4
  • 9
    • 0028014644 scopus 로고
    • Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine
    • Cowman, A. F., Galatis, D., and Thompson, J. K. 1994. Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proceedings of the National Academy of Sciences USA 91, 1143-1147.
    • (1994) Proceedings of the National Academy of Sciences USA , vol.91 , pp. 1143-1147
    • Cowman, A.F.1    Galatis, D.2    Thompson, J.K.3
  • 10
    • 0025786518 scopus 로고
    • A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
    • Cowman, A. F., Karcz, S., Galatis, D., and Culvenor, J. G. 1991. A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole. Journal of Biological Chemistry 113, 1033-1042.
    • (1991) Journal of Biological Chemistry , vol.113 , pp. 1033-1042
    • Cowman, A.F.1    Karcz, S.2    Galatis, D.3    Culvenor, J.G.4
  • 11
    • 0029942616 scopus 로고    scopus 로고
    • Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi
    • Dallagiovanna, B., Gamarro, F., and Castanys, S. 1996. Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi. Molecular and Biochemical Parasitology 75, 145-157.
    • (1996) Molecular and Biochemical Parasitology , vol.75 , pp. 145-157
    • Dallagiovanna, B.1    Gamarro, F.2    Castanys, S.3
  • 16
    • 0024268092 scopus 로고
    • The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes
    • Dreesen, T. D., Johnson, D. H., and Henikoff, S. 1988. The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes. Molecular and Cellular Biology 8, 5206-5215.
    • (1988) Molecular and Cellular Biology , vol.8 , pp. 5206-5215
    • Dreesen, T.D.1    Johnson, D.H.2    Henikoff, S.3
  • 17
    • 0024415802 scopus 로고
    • Multiple drug resistance and conservative amplification of the H region in Leishmania major
    • Ellenberger, T. E., and Beverley, S. M. 1989. Multiple drug resistance and conservative amplification of the H region in Leishmania major. Journal of Biological Chemistry 264, 15094-15103.
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 15094-15103
    • Ellenberger, T.E.1    Beverley, S.M.2
  • 18
    • 0028334009 scopus 로고
    • Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falciparum
    • Foley, M., Deady, L. W., Ng, K., Cowman, A. F., and Tilley, L. 1994. Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falciparum. Journal of Biological Chemistry 269, 6955-6961.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 6955-6961
    • Foley, M.1    Deady, L.W.2    Ng, K.3    Cowman, A.F.4    Tilley, L.5
  • 19
    • 0025269612 scopus 로고
    • Several alleles of the multidrug resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
    • Foote, S. J., Kyle, D. E., Martin, R. K., Oduola, M. J., Forsyth, K., Kemp, D. J., and Cowman, A. F. 1990. Several alleles of the multidrug resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345, 255-258.
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, M.J.4    Forsyth, K.5    Kemp, D.J.6    Cowman, A.F.7
  • 20
    • 0024338609 scopus 로고
    • Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
    • Foote, S. J., Thompson, J. K., Cowman, A. F., and Kemp, D. J. 1989. Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57, 921-930.
    • (1989) Cell , vol.57 , pp. 921-930
    • Foote, S.J.1    Thompson, J.K.2    Cowman, A.F.3    Kemp, D.J.4
  • 21
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. M., and Pastan, I. 1993. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annual Reviews of Biochemistry 62, 385-427.
    • (1993) Annual Reviews of Biochemistry , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 22
    • 0030924243 scopus 로고    scopus 로고
    • Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae
    • Grondin, K., Haimeur, A., Mukhopadhyay, R., Rosen, B. P., and Ouellette, M. 1997. Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae. EMBO Journal 16, 3057-3065.
    • (1997) EMBO Journal , vol.16 , pp. 3057-3065
    • Grondin, K.1    Haimeur, A.2    Mukhopadhyay, R.3    Rosen, B.P.4    Ouellette, M.5
  • 23
    • 0029565603 scopus 로고
    • Leishmania amazonensis: Multidrug resistance in vinblastine-resistant promastigotes is associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr1 gene
    • Gueiros-Filho, F. J., Viola, J. P., Gomes, F. C., Farina, M., Lins, U., Bertho, A. L., Wirth, D. F., and Lopes, U. G. 1995. Leishmania amazonensis: Multidrug resistance in vinblastine-resistant promastigotes is associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr1 gene. Experimental Parasitology 81, 480-490.
    • (1995) Experimental Parasitology , vol.81 , pp. 480-490
    • Gueiros-Filho, F.J.1    Viola, J.P.2    Gomes, F.C.3    Farina, M.4    Lins, U.5    Bertho, A.L.6    Wirth, D.F.7    Lopes, U.G.8
  • 24
    • 0026720137 scopus 로고
    • Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene
    • Henderson, D. M., Sifri, C. D., Rodgers, M., Wirth, D. F., Hendrickson, N., and Ullman, B. 1992. Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene. Molecular and Cellular Biology 12, 2855-2865.
    • (1992) Molecular and Cellular Biology , vol.12 , pp. 2855-2865
    • Henderson, D.M.1    Sifri, C.D.2    Rodgers, M.3    Wirth, D.F.4    Hendrickson, N.5    Ullman, B.6
  • 26
    • 0027984930 scopus 로고
    • Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis
    • Johnson, P. J., Schuck, B. L., and Delgadillo, M. G. 1994. Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis. Molecular and Biochemical Parasitology 66, 127-137.
    • (1994) Molecular and Biochemical Parasitology , vol.66 , pp. 127-137
    • Johnson, P.J.1    Schuck, B.L.2    Delgadillo, M.G.3
  • 28
    • 0024833061 scopus 로고
    • Saccharomyces cerevisiae STE6 gene product: A novel pathway for protein export in eukaryotic cells
    • Kuchler, K., Sterne, R. E., and Thorner, J. 1989. Saccharomyces cerevisiae STE6 gene product: A novel pathway for protein export in eukaryotic cells. EMBO Journal 8, 3973-3984.
    • (1989) EMBO Journal , vol.8 , pp. 3973-3984
    • Kuchler, K.1    Sterne, R.E.2    Thorner, J.3
  • 30
    • 0028855545 scopus 로고
    • An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast
    • Leighton, J., and Schatz, G. 1995. An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast. EMBO Journal 14, 188-195.
    • (1995) EMBO Journal , vol.14 , pp. 188-195
    • Leighton, J.1    Schatz, G.2
  • 31
    • 0030219812 scopus 로고    scopus 로고
    • Plasmodium falciparum: Amplification and overexpression of pfmdr1 is not necessary for increased mefloquine resistance
    • Lim, A. S., Galatis, D., and Cowman, A. F. 1996. Plasmodium falciparum: Amplification and overexpression of pfmdr1 is not necessary for increased mefloquine resistance. Experimental Parasitology 83, 295-303.
    • (1996) Experimental Parasitology , vol.83 , pp. 295-303
    • Lim, A.S.1    Galatis, D.2    Cowman, A.F.3
  • 32
    • 0023137728 scopus 로고
    • Reversal of chloroquine resistance in Plasmodium falciparum by verapamil
    • Martin, S. K., Oduola, A. M., and Milhous, W. K. 1987. Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science 235, 899-901.
    • (1987) Science , vol.235 , pp. 899-901
    • Martin, S.K.1    Oduola, A.M.2    Milhous, W.K.3
  • 34
    • 0025321675 scopus 로고
    • The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene
    • Ouellette, M., Fase-Fowler, F., and Borst, P. 1990. The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene. EMBO Journal 9, 1027-1033.
    • (1990) EMBO Journal , vol.9 , pp. 1027-1033
    • Ouellette, M.1    Fase-Fowler, F.2    Borst, P.3
  • 36
    • 0028365282 scopus 로고
    • Contribution of the Leishmania P-glycoprotein-related gene ltpgpA to oxyanion resistance
    • Papadopoulou, B., Roy, G., Dey, S., Rosen, B. P., and Ouellette, M. 1994. Contribution of the Leishmania P-glycoprotein-related gene ltpgpA to oxyanion resistance. Journal of Biological Chemistry 269, 11980-11986.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 11980-11986
    • Papadopoulou, B.1    Roy, G.2    Dey, S.3    Rosen, B.P.4    Ouellette, M.5
  • 37
    • 0028135205 scopus 로고
    • A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro
    • Peel, S. A., Bright, P., Yount, B., Handy, J., and Baric, R. S. 1994. A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. American Journal of Tropical Medicine and Hygiene 51, 648-658.
    • (1994) American Journal of Tropical Medicine and Hygiene , vol.51 , pp. 648-658
    • Peel, S.A.1    Bright, P.2    Yount, B.3    Handy, J.4    Baric, R.S.5
  • 38
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
    • published erratum appears in Science 1989 Sep 29, 245 (4925), 1437
    • Riordan, J. R., Rommens, J. M., Kerem, B., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J. L., et al. 1989. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA [published erratum appears in Science 1989 Sep 29, 245 (4925), 1437]. Science 245, 1066-1073.
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1    Rommens, J.M.2    Kerem, B.3    Alon, N.4    Rozmahel, R.5    Grzelczak, Z.6    Zielenski, J.7    Lok, S.8    Plavsic, N.9    Chou, J.L.10
  • 39
    • 0030007435 scopus 로고    scopus 로고
    • The ATP-binding cassette (ABC) gene family of Plasmodium falciparum
    • Rubio, J., and Cowman, A. 1996. The ATP-binding cassette (ABC) gene family of Plasmodium falciparum. Parasitology Today 12, 135-140.
    • (1996) Parasitology Today , vol.12 , pp. 135-140
    • Rubio, J.1    Cowman, A.2
  • 40
    • 0028169583 scopus 로고
    • Plasmodium falciparum: The pfmdr2 protein is not overexpressed in chloroquine-resistant isolates of the malaria parasite
    • Rubio, J. P., and Cowman, A. F. 1994. Plasmodium falciparum: the pfmdr2 protein is not overexpressed in chloroquine-resistant isolates of the malaria parasite. Experimental Parasitology 79, 137-147.
    • (1994) Experimental Parasitology , vol.79 , pp. 137-147
    • Rubio, J.P.1    Cowman, A.F.2
  • 41
  • 42
    • 0031037514 scopus 로고    scopus 로고
    • Identification of a chloroquine importer in Plasmodium falciparum. Differences in import kinetics are genetically linked with the chloroquine-resistant phenotype
    • Sanchez, C. P., Wunsch, S., and Lanzer, M. 1997. Identification of a chloroquine importer in Plasmodium falciparum. Differences in import kinetics are genetically linked with the chloroquine-resistant phenotype. Journal of Biological Chemistry 272, 2652-2658.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 2652-2658
    • Sanchez, C.P.1    Wunsch, S.2    Lanzer, M.3
  • 43
    • 0026514177 scopus 로고
    • Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites
    • Slater, A. F., and Cerami, A. 1992. Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites [see comments]. Nature 355, 167-169.
    • (1992) Nature , vol.355 , pp. 167-169
    • Slater, A.F.1    Cerami, A.2
  • 44
    • 0031589733 scopus 로고    scopus 로고
    • Complex polymorphisms in an ∼330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa
    • Su, X., Kirkman, L. A., Fujioka, H., and Wellems, T. E. 1997. Complex polymorphisms in an ∼330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. Cell 91, 593-603.
    • (1997) Cell , vol.91 , pp. 593-603
    • Su, X.1    Kirkman, L.A.2    Fujioka, H.3    Wellems, T.E.4
  • 45
    • 0028064872 scopus 로고
    • A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein
    • Szczypka, M. S., Wemmie, J. A., Moye-Rowley, W. S., and Thiele, D. J. 1994. A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. Journal of Biological Chemistry 269, 22853-22857.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 22853-22857
    • Szczypka, M.S.1    Wemmie, J.A.2    Moye-Rowley, W.S.3    Thiele, D.J.4
  • 46
    • 9544233652 scopus 로고    scopus 로고
    • A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
    • Taniguchi, K., Wada, M., Kohno, K., Nakamura, T., Kawabe, T., Kawakami, M., Kagotani, K., Okumura, K., Akiyama, S., and Kuwano, M. 1996. A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Research 56, 4124-4129.
    • (1996) Cancer Research , vol.56 , pp. 4124-4129
    • Taniguchi, K.1    Wada, M.2    Kohno, K.3    Nakamura, T.4    Kawabe, T.5    Kawakami, M.6    Kagotani, K.7    Okumura, K.8    Akiyama, S.9    Kuwano, M.10
  • 47
    • 0024267730 scopus 로고
    • Sequence of mdr3 cDNA encoding a human P-glycoprotein
    • van der Bliek, A. M., Kooiman, P. M., Schneider, C., and Borst, P. 1988. Sequence of mdr3 cDNA encoding a human P-glycoprotein. Gene 71, 401-411.
    • (1988) Gene , vol.71 , pp. 401-411
    • Van Der Bliek, A.M.1    Kooiman, P.M.2    Schneider, C.3    Borst, P.4
  • 48
    • 0028274565 scopus 로고
    • Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine
    • van Es, H. H., Karcz, S., Chu, F., Cowman, A. F., Vidal, S., Gros, P., and Schurr, E. 1994a. Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine. Molecular and Cellular Biology 14, 2419-2428.
    • (1994) Molecular and Cellular Biology , vol.14 , pp. 2419-2428
    • Van Es, H.H.1    Karcz, S.2    Chu, F.3    Cowman, A.F.4    Vidal, S.5    Gros, P.6    Schurr, E.7
  • 49
    • 0028607543 scopus 로고
    • Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene
    • van Es, H. H., Renkema, H., Aerts, H., and Schurr, E. 1994b. Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene. Molecular and Biochemical Parasitology 68, 209-219.
    • (1994) Molecular and Biochemical Parasitology , vol.68 , pp. 209-219
    • Van Es, H.H.1    Renkema, H.2    Aerts, H.3    Schurr, E.4
  • 50
    • 0029047328 scopus 로고
    • Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr 1 gene of Plasmodium falciparum
    • Volkman, S. K., Cowman, A. F., and Wirth, D. F. 1995. Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr 1 gene of Plasmodium falciparum. Proceedings of the National Academy of Sciences USA 92, 8921-8925.
    • (1995) Proceedings of the National Academy of Sciences USA , vol.92 , pp. 8921-8925
    • Volkman, S.K.1    Cowman, A.F.2    Wirth, D.F.3
  • 53
    • 0024356582 scopus 로고
    • Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
    • Wilson, C. M., Serrano, A. E., Wasley, A., Bogenschutz, M. P., Shankar, A. H., and Wirth, D. F. 1989. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244, 1184-1186.
    • (1989) Science , vol.244 , pp. 1184-1186
    • Wilson, C.M.1    Serrano, A.E.2    Wasley, A.3    Bogenschutz, M.P.4    Shankar, A.H.5    Wirth, D.F.6
  • 55
    • 0028351291 scopus 로고
    • A homologous recombination strategy to analyze the vinblastine resistance property of the V-circle in Leishmania
    • Wong, A. K., Chow, L. M., and Wirth, D. F. 1994. A homologous recombination strategy to analyze the vinblastine resistance property of the V-circle in Leishmania. Molecular and Biochemical Parasitology 64, 75-86.
    • (1994) Molecular and Biochemical Parasitology , vol.64 , pp. 75-86
    • Wong, A.K.1    Chow, L.M.2    Wirth, D.F.3
  • 56
    • 0027442477 scopus 로고
    • Characterization of the pfmdr 2 gene for Plasmodium falciparum
    • published erratum appears in Molecular and Biochemical Parasitology 1994 Feb, 63(2), 311
    • Zalis, M. G., Wilson, C. M., Zhang, Y., and Wirth, D. F. 1993. Characterization of the pfmdr 2 gene for Plasmodium falciparum [published erratum appears in Molecular and Biochemical Parasitology 1994 Feb, 63(2), 311]. Molecular and Biochemical Parasitology 62, 83-92.
    • (1993) Molecular and Biochemical Parasitology , vol.62 , pp. 83-92
    • Zalis, M.G.1    Wilson, C.M.2    Zhang, Y.3    Wirth, D.F.4


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