Inhibition of P-glycoprotein enhances sensitivity of Caenorhabditis elegans to ivermectin

Veterinary Parasitology

Volumn 191, Issue 3-4, 2013, Pages 264-275

  Ardelli, Bernadette F ^a   Prichard, Roger K ^b  

^a BRANDON UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

ABC transporter proteins; Caenorhabditis elegans; Chemosensitizers; Ivermectin; P glycoprotein; Phenotype

Indexed keywords

COLCHICINE; DACTINOMYCIN; DAUNORUBICIN; DOXORUBICIN; DRUG RECEPTOR; ETOPOSIDE; FORSKOLIN; IVERMECTIN; MULTIDRUG RESISTANCE PROTEIN; QUINIDINE; QUININE; RHODAMINE; VERAPAMIL; VINCRISTINE SULFATE; VINDESINE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SENSITIVITY; GENE; GENE EXPRESSION PROFILING; GENE INACTIVATION; GENE LOCATION; INTESTINE; NEMATODE; NERVE CELL; NONHUMAN; PARASITE MIGRATION; PGP 12 GENE; PGP 13 GENE; PGP 2 GENE; PGP 5 GENE; PGP 6 GENE; PGP 7 GENE; PHARYNX; PHENOTYPE; PROTEIN DEPLETION; PROTEIN FUNCTION; REGULATORY MECHANISM; SENSITIVITY ANALYSIS; STRAIN DIFFERENCE; WILD TYPE;

ANIMALS; ANTHELMINTICS; CAENORHABDITIS ELEGANS; CALCIUM CHANNEL BLOCKERS; DRUG RESISTANCE; IVERMECTIN; P-GLYCOPROTEIN; VERAPAMIL;

CAENORHABDITIS ELEGANS; NEMATODA; VERTEBRATA;

EID: 84870864541     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2012.09.021     Document Type: Article

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