-
1
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
doi: 10.1016/S0092-8674(00)81333-1
-
Kinzler KW, Vogelstein B, (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170. doi:10.1016/S0092-8674(00)81333-1. PubMed: 8861899.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
2
-
-
35648988947
-
Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene
-
doi: 10.1242/jcs.03485
-
Aoki K, Taketo MM, (2007) Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene. J Cell Sci 120: 3327-3335. doi:10.1242/jcs.03485. PubMed: 17881494.
-
(2007)
J Cell Sci
, vol.120
, pp. 3327-3335
-
-
Aoki, K.1
Taketo, M.M.2
-
3
-
-
41549117418
-
Cell regulation by the apc protein apc as master regulator of epithelia
-
doi: 10.1016/j.ceb.2008.02.001
-
McCartney BM, Näthke IS, (2008) Cell regulation by the apc protein apc as master regulator of epithelia. Curr Opin Cell Biol 20: 186-193. doi:10.1016/j.ceb.2008.02.001. PubMed: 18359618.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 186-193
-
-
McCartney, B.M.1
Näthke, I.S.2
-
4
-
-
79957597124
-
Deconstructing the sscatenin destruction complex: Mechanistic roles for the tumor suppressor APC in regulating wnt signaling
-
doi: 10.1091/mbc.E10-11-0871
-
Roberts DM, Pronobis MI, Poulton JS, Waldmann JD, Stephenson EM, et al. (2011) Deconstructing the sscatenin destruction complex: Mechanistic roles for the tumor suppressor APC in regulating wnt signaling. Mol Cell Biol 22: 1845-1863. doi:10.1091/mbc.E10-11-0871.
-
(2011)
Mol Cell Biol
, vol.22
, pp. 1845-1863
-
-
Roberts, D.M.1
Pronobis, M.I.2
Poulton, J.S.3
Waldmann, J.D.4
Stephenson, E.M.5
-
5
-
-
0027738023
-
Association of the APC gene product with beta-catenin
-
doi: 10.1126/science.8259518
-
Rubinfeld B, Souza B, Albert I, Müller O, Chamberlain SH, et al. (1993) Association of the APC gene product with beta-catenin. Science 262: 1731-1734. doi:10.1126/science.8259518. PubMed: 8259518.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Müller, O.4
Chamberlain, S.H.5
-
6
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
doi: 10.1126/science.8259519
-
Su LK, Vogelstein B, Kinzler KW, (1993) Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737. doi:10.1126/science.8259519. PubMed: 8259519.
-
(1993)
Science
, vol.262
, pp. 1734-1737
-
-
Su, L.K.1
Vogelstein, B.2
Kinzler, K.W.3
-
7
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
-
doi: 10.1126/science.280.5363.596
-
Behrens J, Jerchow BA, Würtele M, Grimm J, Asbrand C, et al. (1998) Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 280: 596-599. doi:10.1126/science.280.5363.596. PubMed: 9554852.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Würtele, M.3
Grimm, J.4
Asbrand, C.5
-
8
-
-
0032079884
-
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin
-
doi: 10.1074/jbc.273.18.10823
-
Kishida S, Yamamoto H, Ikeda S, Kishida M, Sakamoto I, et al. (1998) Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin. J Biol Chem 273: 10823-10826. doi:10.1074/jbc.273.18.10823. PubMed: 9556553.
-
(1998)
J Biol Chem
, vol.273
, pp. 10823-10826
-
-
Kishida, S.1
Yamamoto, H.2
Ikeda, S.3
Kishida, M.4
Sakamoto, I.5
-
9
-
-
0031813650
-
Axin, an inhibitor of the wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level
-
doi: 10.1046/j.1365-2443.1998.00198.x
-
Nakamura T, Hamada F, Ishidate T, Anai K, Kawahara K, et al. (1998) Axin, an inhibitor of the wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level. Genes Cells 3: 395-403. doi:10.1046/j.1365-2443.1998.00198.x. PubMed: 9734785.
-
(1998)
Genes Cells
, vol.3
, pp. 395-403
-
-
Nakamura, T.1
Hamada, F.2
Ishidate, T.3
Anai, K.4
Kawahara, K.5
-
10
-
-
0034657187
-
Structural basis of the axin-adenomatous polyposis coli interaction
-
doi: 10.1093/emboj/19.10.2270
-
Spink KE, Polakis P, Weis WI, (2000) Structural basis of the axin-adenomatous polyposis coli interaction. EMBO J 19: 2270-2279. doi:10.1093/emboj/19.10.2270. PubMed: 10811618.
-
(2000)
EMBO J
, vol.19
, pp. 2270-2279
-
-
Spink, K.E.1
Polakis, P.2
Weis, W.I.3
-
11
-
-
0035890060
-
Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex
-
doi: 10.1093/emboj/20.22.6203
-
Eklof Spink K, Fridman SG, Weis WI, (2001) Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. EMBO J 20: 6203-6212. doi:10.1093/emboj/20.22.6203. PubMed: 11707392.
-
(2001)
EMBO J
, vol.20
, pp. 6203-6212
-
-
Eklof Spink, K.1
Fridman, S.G.2
Weis, W.I.3
-
12
-
-
4344562126
-
Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
-
doi: 10.1016/j.molcel.2004.08.010
-
Ha NC, Tonozuka T, Stamos JL, Choi HJ, Weis WI, (2004) Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Mol Cell 15: 511-521. doi:10.1016/j.molcel.2004.08.010. PubMed: 15327768.
-
(2004)
Mol Cell
, vol.15
, pp. 511-521
-
-
Ha, N.C.1
Tonozuka, T.2
Stamos, J.L.3
Choi, H.J.4
Weis, W.I.5
-
13
-
-
77956537091
-
The WTX/AMER1 gene family: Evolution, signature and function
-
doi: 10.1186/1471-2148-10-280
-
Boutet A, Comai G, Schedl A, (2010) The WTX/AMER1 gene family: Evolution, signature and function. BMC Evol Biol 10280:: 280-. doi:10.1186/1471-2148-10-280. PubMed: 20843316.
-
(2010)
BMC Evol Biol
, vol.10
, pp. 280
-
-
Boutet, A.1
Comai, G.2
Schedl, A.3
-
14
-
-
79955009076
-
1/WTX couples wnt-induced formation of PtdIns(4,5). AmerP2to LRP6 phosphorylation
-
doi: 10.1038/emboj.2011.28
-
Tanneberger K, Pfister AS, Brauburger K, Schneikert J, Hadjihannas MV, et al. (2011) 1/WTX couples wnt-induced formation of PtdIns(4,5). AmerP2to LRP6 phosphorylation. EMBO J 30: 1433-1443 doi:10.1038/emboj.2011.28.
-
(2011)
EMBO J
, vol.30
, pp. 1433-1443
-
-
Tanneberger, K.1
Pfister, A.S.2
Brauburger, K.3
Schneikert, J.4
Hadjihannas, M.V.5
-
15
-
-
84856635802
-
Triple SILAC to determine stimulus specific interactions in the wnt pathway
-
doi: 10.1021/pr200740a
-
Hilger M, Mann M, (2012) Triple SILAC to determine stimulus specific interactions in the wnt pathway. J Proteome Res 11: 982-994. doi:10.1021/pr200740a. PubMed: 22011079.
-
(2012)
J Proteome Res
, vol.11
, pp. 982-994
-
-
Hilger, M.1
Mann, M.2
-
16
-
-
84861972831
-
Wnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complex
-
doi: 10.1016/j.cell.2012.05.002
-
Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, et al. (2012) Wnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complex. Cell 149: 1245-1256. doi:10.1016/j.cell.2012.05.002. PubMed: 22682247.
-
(2012)
Cell
, vol.149
, pp. 1245-1256
-
-
Li, V.S.1
Ng, S.S.2
Boersema, P.J.3
Low, T.Y.4
Karthaus, W.R.5
-
17
-
-
5444233462
-
APC dosage effects in tumorigenesis and stem cell differentiation
-
doi: 10.1387/ijdb.041807cg
-
Gaspar C, Fodde R, (2004) APC dosage effects in tumorigenesis and stem cell differentiation. Int J Dev Biol 48: 377-386. doi:10.1387/ijdb.041807cg. PubMed: 15349813.
-
(2004)
Int J Dev Biol
, vol.48
, pp. 377-386
-
-
Gaspar, C.1
Fodde, R.2
-
18
-
-
80052028694
-
Messing up disorder: How do missense mutations in the tumor suppressor protein APC lead to cancer?
-
doi: 10.1186/1476-4598-10-101
-
Minde DP, Anvarian Z, Rüdiger SGD, Maurice MM, (2011) Messing up disorder: How do missense mutations in the tumor suppressor protein APC lead to cancer? Mol Cancer 10101:: 101-. doi:10.1186/1476-4598-10-101. PubMed: 21859464.
-
(2011)
Mol Cancer
, vol.10
, pp. 101
-
-
Minde, D.P.1
Anvarian, Z.2
Rüdiger, S.G.D.3
Maurice, M.M.4
-
19
-
-
4344684495
-
Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function
-
doi: 10.1016/j.molcel.2004.08.001
-
Xing Y, Clements WK, Le Trong I, Hinds TR, Stenkamp R, et al. (2004) Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function. Mol Cell 15: 523-533. doi:10.1016/j.molcel.2004.08.001. PubMed: 15327769.
-
(2004)
Mol Cell
, vol.15
, pp. 523-533
-
-
Xing, Y.1
Clements, W.K.2
Le Trong, I.3
Hinds, T.R.4
Stenkamp, R.5
-
20
-
-
33745276261
-
The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin
-
doi: 10.1016/j.jmb.2006.04.064
-
Liu J, Xing Y, Hinds TR, Zheng J, Xu W, (2006) The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin. J Mol Biol 360: 133-144. doi:10.1016/j.jmb.2006.04.064. PubMed: 16753179.
-
(2006)
J Mol Biol
, vol.360
, pp. 133-144
-
-
Liu, J.1
Xing, Y.2
Hinds, T.R.3
Zheng, J.4
Xu, W.5
-
21
-
-
35448947338
-
Chemical dissection of the APC repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3
-
doi: 10.1021/bi701674z
-
Ferrarese A, Marin O, Bustos VH, Venerando A, Antonelli M, et al. (2007) Chemical dissection of the APC repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3. Biochemistry 46: 11902-11910. doi:10.1021/bi701674z. PubMed: 17910481.
-
(2007)
Biochemistry
, vol.46
, pp. 11902-11910
-
-
Ferrarese, A.1
Marin, O.2
Bustos, V.H.3
Venerando, A.4
Antonelli, M.5
-
22
-
-
0037199975
-
The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). its structure and its interaction with chromosome maintenance region 1 (crm-1)
-
doi: 10.1074/jbc.M203990200
-
Tickenbrock L, Cramer J, Vetter IR, Muller O, (2002) The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). its structure and its interaction with chromosome maintenance region 1 (crm-1). J Biol Chem 277: 32332-32338. doi:10.1074/jbc.M203990200. PubMed: 12070164.
-
(2002)
J Biol Chem
, vol.277
, pp. 32332-32338
-
-
Tickenbrock, L.1
Cramer, J.2
Vetter, I.R.3
Muller, O.4
-
23
-
-
80054060426
-
Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of Sam68
-
doi: 10.1016/j.str.2011.07.013
-
Morishita EC, Murayama K, Kato-Murayama M, Ishizuka-Katsura Y, Tomabechi Y, et al. (2011) Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of Sam68. Structure 19: 1496-1508. doi:10.1016/j.str.2011.07.013. PubMed: 22000517.
-
(2011)
Structure
, vol.19
, pp. 1496-1508
-
-
Morishita, E.C.1
Murayama, K.2
Kato-Murayama, M.3
Ishizuka-Katsura, Y.4
Tomabechi, Y.5
-
24
-
-
84856592108
-
Structural basis for the recognition of asef by adenomatous polyposis coli
-
doi: 10.1038/cr.2011.119, Retrieved onpublished at whilst December year 1111 from
-
Zhang Z, Chen L, Gao L, Lin K, Zhu L, et al. (2012) Structural basis for the recognition of asef by adenomatous polyposis coli. Cell Res 22: 372-386. doi:10.1038/cr.2011.119. PubMed: 21788986; Retrieved onpublished at whilst December year 1111 from. doi:10.1038/cr.2011.119.
-
(2012)
Cell Res
, vol.22
, pp. 372-386
-
-
Zhang, Z.1
Chen, L.2
Gao, L.3
Lin, K.4
Zhu, L.5
-
25
-
-
80052633958
-
Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility
-
doi: 10.1016/j.bbrc.2011.08.044
-
Zhang Z, Lin K, Gao L, Chen L, Shi X, et al. (2011) Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility. Biochem Biophys Res Commun 412: 732-736. doi:10.1016/j.bbrc.2011.08.044. PubMed: 21871439.
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 732-736
-
-
Zhang, Z.1
Lin, K.2
Gao, L.3
Chen, L.4
Shi, X.5
-
26
-
-
0034604366
-
Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor
-
doi: 10.1006/jmbi.2000.3895
-
Day CL, Alber T, (2000) Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor. J Mol Biol 301: 147-156. doi:10.1006/jmbi.2000.3895. PubMed: 10926498.
-
(2000)
J Mol Biol
, vol.301
, pp. 147-156
-
-
Day, C.L.1
Alber, T.2
-
27
-
-
39049097331
-
Multiple rare nonsynonymous variants in the adenomatous polyposis coli gene predispose to colorectal adenomas
-
doi: 10.1158/0008-5472.CAN-07-5733
-
Azzopardi D, Dallosso AR, Eliason K, Hendrickson BC, Jones N, et al. (2008) Multiple rare nonsynonymous variants in the adenomatous polyposis coli gene predispose to colorectal adenomas. Cancer Res 68: 358-363. doi:10.1158/0008-5472.CAN-07-5733. PubMed: 18199528.
-
(2008)
Cancer Res
, vol.68
, pp. 358-363
-
-
Azzopardi, D.1
Dallosso, A.R.2
Eliason, K.3
Hendrickson, B.C.4
Jones, N.5
-
28
-
-
45749140081
-
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours
-
doi: 10.1093/hmg/ddn095
-
Kohler EM, Derungs A, Daum G, Behrens J, Schneikert J, (2008) Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours. Hum Mol Genet 17: 1978-1987. doi:10.1093/hmg/ddn095. PubMed: 18387968.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1978-1987
-
-
Kohler, E.M.1
Derungs, A.2
Daum, G.3
Behrens, J.4
Schneikert, J.5
-
29
-
-
84859320307
-
The roles of intrinsic disorder in orchestrating the wnt-pathway
-
doi: 10.1080/073911012010525024
-
Xue B, Dunker AK, Uversky VN, (2012) The roles of intrinsic disorder in orchestrating the wnt-pathway. J Biomol Struct Dyn 29: 843-861. doi:10.1080/073911012010525024. PubMed: 22292947.
-
(2012)
J Biomol Struct Dyn
, vol.29
, pp. 843-861
-
-
Xue, B.1
Dunker, A.K.2
Uversky, V.N.3
-
30
-
-
77951645923
-
Sequence determinants of compaction in intrinsically disordered proteins
-
doi: 10.1016/j.bpj.2010.02.006
-
Marsh JA, Forman-Kay JD, (2010) Sequence determinants of compaction in intrinsically disordered proteins. Biophys J 98: 2383-2390. doi:10.1016/j.bpj.2010.02.006. PubMed: 20483348.
-
(2010)
Biophys J
, vol.98
, pp. 2383-2390
-
-
Marsh, J.A.1
Forman-Kay, J.D.2
-
31
-
-
77957092799
-
From the cover: Charge interactions can dominate the dimensions of intrinsically disordered proteins
-
doi: 10.1073/pnas.1001743107
-
Müller-Späth S, Soranno A, Hirschfeld V, Hofmann H, Rüegger S, et al. (2010) From the cover: Charge interactions can dominate the dimensions of intrinsically disordered proteins. Proc Natl Acad Sci U S A 107: 14609-14614. doi:10.1073/pnas.1001743107. PubMed: 20639465.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14609-14614
-
-
Müller-Späth, S.1
Soranno, A.2
Hirschfeld, V.3
Hofmann, H.4
Rüegger, S.5
-
32
-
-
0035961594
-
High-temperature protein mass mapping using a thermophilic protease
-
doi: 10.1021/ja002909n
-
Bark SJ, Muster N, Yates JR 3rd, Siuzdak G, (2001) High-temperature protein mass mapping using a thermophilic protease. J Am Chem Soc 123: 1774-1775. doi:10.1021/ja002909n. PubMed: 11456785.
-
(2001)
J Am Chem Soc
, vol.123
, pp. 1774-1775
-
-
Bark, S.J.1
Muster, N.2
Yates 3rd, J.R.3
Siuzdak, G.4
-
33
-
-
0030028728
-
Principles of protein-protein interactions
-
doi: 10.1073/pnas.93.1.13
-
Jones S, Thornton JM, (1996) Principles of protein-protein interactions. Proc Natl Acad Sci U S A 93: 13-20. doi:10.1073/pnas.93.1.13. PubMed: 8552589.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13-20
-
-
Jones, S.1
Thornton, J.M.2
-
34
-
-
84859590040
-
Folding without charges
-
doi: 10.1073/pnas.1118640109
-
Kurnik M, Hedberg L, Danielsson J, Oliveberg M, (2012) Folding without charges. Proc Natl Acad Sci U S A 109: 5705-5710. doi:10.1073/pnas.1118640109. PubMed: 22454493.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 5705-5710
-
-
Kurnik, M.1
Hedberg, L.2
Danielsson, J.3
Oliveberg, M.4
-
35
-
-
18744391410
-
Pulse proteolysis: A simple method for quantitative determination of protein stability and ligand binding
-
doi: 10.1038/nmeth740
-
Park C, Marqusee S, (2005) Pulse proteolysis: A simple method for quantitative determination of protein stability and ligand binding. Nat Methods 2: 207-212. doi:10.1038/nmeth740. PubMed: 15782190.
-
(2005)
Nat Methods
, vol.2
, pp. 207-212
-
-
Park, C.1
Marqusee, S.2
-
36
-
-
84867090696
-
Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTpp
-
doi: 10.1371/journal.pone.0046147, Retrieved onpublished at whilst December year 1111 from
-
Minde DP, Maurice MM, Rüdiger SGD, (2012) Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTpp. PLOS ONE 7: e46147. doi:10.1371/journal.pone.0046147. PubMed: 23056252; Retrieved onpublished at whilst December year 1111 from. doi:10.1371/journal.pone.0046147.
-
(2012)
PLOS ONE
, vol.7
-
-
Minde, D.P.1
Maurice, M.M.2
Rüdiger, S.G.D.3
-
37
-
-
78650858373
-
Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded
-
doi: 10.1016/j.jmb.2010.11.013
-
Noutsou M, Duarte AM, Anvarian Z, Didenko T, Minde DP, et al. (2011) Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded. J Mol Biol 405: 773-786. doi:10.1016/j.jmb.2010.11.013. PubMed: 21087614.
-
(2011)
J Mol Biol
, vol.405
, pp. 773-786
-
-
Noutsou, M.1
Duarte, A.M.2
Anvarian, Z.3
Didenko, T.4
Minde, D.P.5
-
38
-
-
0028009873
-
Characterization of a trifluoroethanol-induced partially folded state of alpha-lactalbumin
-
doi: 10.1006/jmbi.1994.1015
-
Alexandrescu AT, Ng YL, Dobson CM, (1994) Characterization of a trifluoroethanol-induced partially folded state of alpha-lactalbumin. J Mol Biol 235: 587-599. doi:10.1006/jmbi.1994.1015. PubMed: 8289283.
-
(1994)
J Mol Biol
, vol.235
, pp. 587-599
-
-
Alexandrescu, A.T.1
Ng, Y.L.2
Dobson, C.M.3
-
39
-
-
78049336297
-
Residue-specific side-chain packing determines the backbone dynamics of transmembrane model helices
-
doi: 10.1016/j.bpj.2010.08.031
-
Quint S, Widmaier S, Minde D, Hornburg D, Langosch D, et al. (2010) Residue-specific side-chain packing determines the backbone dynamics of transmembrane model helices. Biophys J 99: 2541-2549. doi:10.1016/j.bpj.2010.08.031. PubMed: 20959095.
-
(2010)
Biophys J
, vol.99
, pp. 2541-2549
-
-
Quint, S.1
Widmaier, S.2
Minde, D.3
Hornburg, D.4
Langosch, D.5
-
40
-
-
0034601093
-
Protein folding transition states: Elicitation of hammond effects by febbraio,2,2-trifluoroethanol
-
doi: 10.1002/1439-7633(20000703)1:1
-
Yiu CP, Mateu MG, Fersht AR, (2000) Protein folding transition states: Elicitation of hammond effects by febbraio,2,2-trifluoroethanol. Chembiochem 1: 49-55. doi:10.1002/1439-7633(20000703)1:1. PubMed: 11828398.
-
(2000)
Chembiochem
, vol.1
, pp. 49-55
-
-
Yiu, C.P.1
Mateu, M.G.2
Fersht, A.R.3
-
41
-
-
0032748895
-
Theoretical studies toward quantitative protein circular dichroism calculations
-
Besley NA, Hirst JD, (1999) Theoretical studies toward quantitative protein circular dichroism calculations. J Am Chem Soc 121: 9636-9644. Available: http://dx.doi.org/10.1021/ja990627l via the Internet.
-
(1999)
J Am Chem Soc
, vol.121
, pp. 9636-9644
-
-
Besley, N.A.1
Hirst, J.D.2
-
42
-
-
0038502170
-
Folding dynamics and mechanism of beta-hairpin formation
-
doi: 10.1038/36626
-
Muñoz V, Thompson PA, Hofrichter J, Eaton WA, (1997) Folding dynamics and mechanism of beta-hairpin formation. Nature 390196-199:: 196-9. doi:10.1038/36626. PubMed: 9367160.
-
(1997)
Nature
, vol.390
, pp. 196-199
-
-
Muñoz, V.1
Thompson, P.A.2
Hofrichter, J.3
Eaton, W.A.4
-
43
-
-
44149105911
-
PHOSIDA (phosphorylation site database): Management, structural and evolutionary investigation, and prediction of phosphosites
-
doi: 10.1186/gb-2007-8-11-r250
-
Gnad F, Ren S, Cox J, Olsen JV, Macek B, et al. (2007) PHOSIDA (phosphorylation site database): Management, structural and evolutionary investigation, and prediction of phosphosites. Genome Biol 8R250:: R250-. doi:10.1186/gb-2007-8-11-r250. PubMed: 18039369.
-
(2007)
Genome Biol
, vol.8
-
-
Gnad, F.1
Ren, S.2
Cox, J.3
Olsen, J.V.4
Macek, B.5
-
44
-
-
73349138284
-
Separation and detection of large phosphoproteins using phos-tag SDS-PAGE
-
doi: 10.1038/nprot.2009.154
-
Kinoshita E, Kinoshita-Kikuta E, Koike T, (2009) Separation and detection of large phosphoproteins using phos-tag SDS-PAGE. Nat Protoc 4: 1513-1521. doi:10.1038/nprot.2009.154. PubMed: 19798084.
-
(2009)
Nat Protoc
, vol.4
, pp. 1513-1521
-
-
Kinoshita, E.1
Kinoshita-Kikuta, E.2
Koike, T.3
-
45
-
-
49749115736
-
Separation of phosphoprotein isotypes having the same number of phosphate groups using phosphate-affinity SDS-PAGE
-
doi: 10.1002/pmic.200800243
-
Kinoshita E, Kinoshita-Kikuta E, Matsubara M, Yamada S, Nakamura H, et al. (2008) Separation of phosphoprotein isotypes having the same number of phosphate groups using phosphate-affinity SDS-PAGE. Proteomics 8: 2994-3003. doi:10.1002/pmic.200800243. PubMed: 18615432.
-
(2008)
Proteomics
, vol.8
, pp. 2994-3003
-
-
Kinoshita, E.1
Kinoshita-Kikuta, E.2
Matsubara, M.3
Yamada, S.4
Nakamura, H.5
-
46
-
-
33645714857
-
Phosphate-binding tag, a new tool to visualize phosphorylated proteins
-
doi: 10.1074/mcp.T500024-MCP200
-
Kinoshita E, Kinoshita-Kikuta E, Takiyama K, Koike T, (2006) Phosphate-binding tag, a new tool to visualize phosphorylated proteins. Mol Cell Proteomics 5: 749-757. doi:10.1074/mcp.T500024-MCP200. PubMed: 16340016.
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 749-757
-
-
Kinoshita, E.1
Kinoshita-Kikuta, E.2
Takiyama, K.3
Koike, T.4
-
47
-
-
62849122802
-
Interactions between casein kinase iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificity
-
doi: 10.1371/journal.pone.0004766
-
Dahlberg CL, Nguyen EZ, Goodlett D, Kimelman D, (2009) Interactions between casein kinase iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificity. PLOS ONE 4: e4766. doi:10.1371/journal.pone.0004766. PubMed: 19274088.
-
(2009)
PLOS ONE
, vol.4
-
-
Dahlberg, C.L.1
Nguyen, E.Z.2
Goodlett, D.3
Kimelman, D.4
-
48
-
-
76849087968
-
PONDR-FIT: A meta-predictor of intrinsically disordered amino acids
-
doi: 10.1016/j.bbapap.2010.01.011
-
Xue B, Dunbrack RL, Williams RW, Dunker AK, Uversky VN, (2010) PONDR-FIT: A meta-predictor of intrinsically disordered amino acids. Biochim Biophys Acta 1804: 996-1010. doi:10.1016/j.bbapap.2010.01.011. PubMed: 20100603.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 996-1010
-
-
Xue, B.1
Dunbrack, R.L.2
Williams, R.W.3
Dunker, A.K.4
Uversky, V.N.5
-
49
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
-
doi: 10.1038/nrm2918
-
Taipale M, Jarosz DF, Lindquist S, (2010) HSP90 at the hub of protein homeostasis: Emerging mechanistic insights. Nat Rev Mol Cell Biol 11: 515-528. doi:10.1038/nrm2918. PubMed: 20531426.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
50
-
-
20444384040
-
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex
-
doi: 10.1038/nature03588
-
Reverter D, Lima CD, (2005) Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature 435: 687-692. doi:10.1038/nature03588. PubMed: 15931224.
-
(2005)
Nature
, vol.435
, pp. 687-692
-
-
Reverter, D.1
Lima, C.D.2
-
51
-
-
70450270900
-
Awakening guardian angels: Drugging the p53 pathway
-
doi: 10.1038/nrc2763
-
Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP, (2009) Awakening guardian angels: Drugging the p53 pathway. Nat Rev Cancer 9: 862-873. doi:10.1038/nrc2763. PubMed: 19935675.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 862-873
-
-
Brown, C.J.1
Lain, S.2
Verma, C.S.3
Fersht, A.R.4
Lane, D.P.5
-
52
-
-
47649096991
-
Structural biology of the tumor suppressor p53
-
doi: 10.1146/annurev.biochem.77.060806.091238
-
Joerger AC, Fersht AR, (2008) Structural biology of the tumor suppressor p53. Annu Rev Biochem 77: 557-582. doi:10.1146/annurev.biochem.77.060806.091238. PubMed: 18410249.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 557-582
-
-
Joerger, A.C.1
Fersht, A.R.2
-
53
-
-
68049093193
-
Direct observation of the dynamic process underlying allosteric signal transmission
-
doi: 10.1021/ja809947w
-
Brüschweiler S, Schanda P, Kloiber K, Brutscher B, Kontaxis G, et al. (2009) Direct observation of the dynamic process underlying allosteric signal transmission. J Am Chem Soc 131: 3063-3068. doi:10.1021/ja809947w. PubMed: 19203263.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 3063-3068
-
-
Brüschweiler, S.1
Schanda, P.2
Kloiber, K.3
Brutscher, B.4
Kontaxis, G.5
-
54
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
doi: 10.1126/science.1056784
-
Nucifora FC Jr, Sasaki M, Peters MF, Huang H, Cooper JK, et al. (2001) Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 291: 2423-2428. doi:10.1126/science.1056784. PubMed: 11264541.
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora Jr., F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
-
55
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
doi: 10.1126/science.7545954
-
Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, et al. (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266: 66-71. doi:10.1126/science.7545954. PubMed: 7545954.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
-
56
-
-
48249097986
-
Intrinsically disordered proteins in human diseases: Introducing the D2 concept
-
doi: 10.1146/annurev.biophys.37.032807.125924
-
Uversky VN, Oldfield CJ, Dunker AK, (2008) Intrinsically disordered proteins in human diseases: Introducing the D2 concept. Annu Rev Biophys 37: 215-246. doi:10.1146/annurev.biophys.37.032807.125924. PubMed: 18573080.
-
(2008)
Annu Rev Biophys
, vol.37
, pp. 215-246
-
-
Uversky, V.N.1
Oldfield, C.J.2
Dunker, A.K.3
-
57
-
-
34249930064
-
Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain
-
doi: 10.1107/S1744309107022579
-
Shibata N, Tomimoto Y, Hanamura T, Yamamoto R, Ueda M, et al. (2007) Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain. Acta Crystallogr Sect Struct Biol Cryst Commun 63529-531:: 529-31. doi:10.1107/S1744309107022579. PubMed: 17554179.
-
(2007)
Acta Crystallogr Sect Struct Biol Cryst Commun
, vol.63
, pp. 529-531
-
-
Shibata, N.1
Tomimoto, Y.2
Hanamura, T.3
Yamamoto, R.4
Ueda, M.5
-
58
-
-
77949916296
-
Understanding protein non-folding
-
doi: 10.1016/j.bbapap.2010.01.017
-
Uversky VN, Dunker AK, (2010) Understanding protein non-folding. Biochim Biophys Acta 1804: 1231-1264. doi:10.1016/j.bbapap.2010.01.017. PubMed: 20117254.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1231-1264
-
-
Uversky, V.N.1
Dunker, A.K.2
-
59
-
-
84859701551
-
Orderly order in protein intrinsic disorder distribution: Disorder in 3500 proteomes from viruses and the three domains of life
-
doi: 10.1080/07391102.2012.675145
-
Xue B, Dunker AK, Uversky VN, (2012) Orderly order in protein intrinsic disorder distribution: Disorder in 3500 proteomes from viruses and the three domains of life. J Biomol Struct Dyn 30: 137-149. doi:10.1080/07391102.2012.675145. PubMed: 22702725.
-
(2012)
J Biomol Struct Dyn
, vol.30
, pp. 137-149
-
-
Xue, B.1
Dunker, A.K.2
Uversky, V.N.3
-
60
-
-
67650665028
-
High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1
-
doi: 10.1111/j.1742-4658.2009.07090.x, Retrieved onpublished at whilst December year 1111 from
-
Balázs A, Csizmok V, Buday L, Rakács M, Kiss R, et al. (2009) High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1. FEBS J 276: 3744-3756. doi:10.1111/j.1742-4658.2009.07090.x. PubMed: 19523119; Retrieved onpublished at whilst December year 1111 from.
-
(2009)
FEBS J
, vol.276
, pp. 3744-3756
-
-
Balázs, A.1
Csizmok, V.2
Buday, L.3
Rakács, M.4
Kiss, R.5
-
61
-
-
50049097448
-
Intrinsic disorder in scaffold proteins: Getting more from less
-
PubMed: 18619997, 85-106. 23 September 2009
-
Cortese MS, Uversky VN, Keith Dunker A, (2008) Intrinsic disorder in scaffold proteins: Getting more from less. Prog Biophys Mol Biol 98: 85-106: 85-106. 23 September 2009 PubMed: 18619997.
-
(2008)
Prog Biophys Mol Biol
, vol.98
, pp. 85-106
-
-
Cortese, M.S.1
Uversky, V.N.2
Keith Dunker, A.3
-
62
-
-
79958059909
-
Protein disorder--a breakthrough invention of evolution?
-
doi: 10.1016/j.sbi.2011.03.014
-
Schlessinger A, Schaefer C, Vicedo E, Schmidberger M, Punta M, et al. (2011) Protein disorder--a breakthrough invention of evolution? Curr Opin Struct Biol 21: 412-418. doi:10.1016/j.sbi.2011.03.014. PubMed: 21514145.
-
(2011)
Curr Opin Struct Biol
, vol.21
, pp. 412-418
-
-
Schlessinger, A.1
Schaefer, C.2
Vicedo, E.3
Schmidberger, M.4
Punta, M.5
-
63
-
-
77949629173
-
Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be
-
doi: 10.1093/bioinformatics/btq012
-
Schaefer C, Schlessinger A, Rost B, (2010) Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be. Bioinformatics 26: 625-631. doi:10.1093/bioinformatics/btq012. PubMed: 20081223.
-
(2010)
Bioinformatics
, vol.26
, pp. 625-631
-
-
Schaefer, C.1
Schlessinger, A.2
Rost, B.3
-
64
-
-
0037459238
-
Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein
-
doi: 10.1016/S0022-2836(03)00144-X
-
Tickenbrock L, Kössmeier K, Rehmann H, Herrmann C, Müller O, (2003) Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein. J Mol Biol 327: 359-367. doi:10.1016/S0022-2836(03)00144-X. PubMed: 12628243.
-
(2003)
J Mol Biol
, vol.327
, pp. 359-367
-
-
Tickenbrock, L.1
Kössmeier, K.2
Rehmann, H.3
Herrmann, C.4
Müller, O.5
-
65
-
-
40049101403
-
Crystal structure of a full-length beta-catenin
-
doi: 10.1016/j.str.2007.12.021
-
Xing Y, Takemaru K, Liu J, Berndt JD, Zheng JJ, et al. (2008) Crystal structure of a full-length beta-catenin. Structure 16: 478-487. doi:10.1016/j.str.2007.12.021. PubMed: 18334222.
-
(2008)
Structure
, vol.16
, pp. 478-487
-
-
Xing, Y.1
Takemaru, K.2
Liu, J.3
Berndt, J.D.4
Zheng, J.J.5
-
66
-
-
84878224022
-
Stochastic machines as a colocalization mechanism for scaffold protein function
-
doi: 10.1016/j.febslet.2013.04.006, Retrieved onpublished at whilst December year 1111 from
-
Xue B, Romero PR, Noutsou M, Maurice MM, Rüdiger SGD, et al. (2013) Stochastic machines as a colocalization mechanism for scaffold protein function. FEBS Lett 587: 1587-1591. doi:10.1016/j.febslet.2013.04.006. PubMed: 23603389; Retrieved onpublished at whilst December year 1111 from.
-
(2013)
FEBS Lett
, vol.587
, pp. 1587-1591
-
-
Xue, B.1
Romero, P.R.2
Noutsou, M.3
Maurice, M.M.4
Rüdiger, S.G.D.5
-
67
-
-
57049095821
-
Function and structure of inherently disordered proteins
-
PubMed: 18952168, 756-764. 23 September 2009
-
Dunker AK, Silman I, Uversky VN, Sussman JL, (2008) Function and structure of inherently disordered proteins. Curr Opin Struct Biol 18: 756-64: 756-764. 23 September 2009 PubMed: 18952168.
-
(2008)
Curr Opin Struct Biol
, vol.18
, pp. 756-764
-
-
Dunker, A.K.1
Silman, I.2
Uversky, V.N.3
Sussman, J.L.4
-
68
-
-
78149481137
-
Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration
-
doi: 10.1186/bcr2581
-
Foldynová-Trantírková S, Sekyrová P, Tmejová K, Brumovská E, Bernatík O, et al. (2010) Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration. Breast Cancer Res 12R30:: R30-. doi:10.1186/bcr2581. PubMed: 20507565.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Foldynová-Trantírková, S.1
Sekyrová, P.2
Tmejová, K.3
Brumovská, E.4
Bernatík, O.5
-
69
-
-
33644670810
-
Quantitation of protein on gels and blots by infrared fluorescence of coomassie blue and fast green
-
doi: 10.1016/j.ab.2005.10.048
-
Luo S, Wehr NB, Levine RL, (2006) Quantitation of protein on gels and blots by infrared fluorescence of coomassie blue and fast green. Anal Biochem 350: 233-238. doi:10.1016/j.ab.2005.10.048. PubMed: 16336940.
-
(2006)
Anal Biochem
, vol.350
, pp. 233-238
-
-
Luo, S.1
Wehr, N.B.2
Levine, R.L.3
-
70
-
-
58049196841
-
Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours
-
doi: 10.1093/hmg/ddn338
-
Kohler EM, Chandra SH, Behrens J, Schneikert J, (2009) Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours. Hum Mol Genet 18: 213-226. doi:10.1093/hmg/ddn338. PubMed: 18854359.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 213-226
-
-
Kohler, E.M.1
Chandra, S.H.2
Behrens, J.3
Schneikert, J.4
|