Messing up disorder: How do missense mutations in the tumor suppressor protein APC lead to cancer?

Molecular Cancer

Volumn 10, Issue , 2011, Pages

  Minde, David P ^a   Anvarian, Zeinab ^b   Rüdiger, Stefan G D ^a   Maurice, Madelon M ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; WNT PROTEIN;

CARCINOGENESIS; CELL FUNCTION; COLON CANCER; COMPLEX FORMATION; GERM LINE; HUMAN; MISSENSE MUTATION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL TRANSFORMATION; CHEMISTRY; COLON POLYPOSIS; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; PHYSIOLOGY; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; TUMOR SUPPRESSOR GENE;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; GENES, APC; GENES, TUMOR SUPPRESSOR; HUMANS; MODELS, BIOLOGICAL; MUTATION, MISSENSE; NEOPLASMS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 80052028694     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-10-101     Document Type: Review

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