-
1
-
-
11144265811
-
Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier
-
Augustine LM, Markelewicz RJ, Jr, Boekelheide K, and Cherrington NJ (2005) Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier. Drug Metab Dispos 33:182-189.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 182-189
-
-
Augustine, L.M.1
Markelewicz Jr., R.J.2
Boekelheide, K.3
Cherrington, N.J.4
-
2
-
-
0035038177
-
Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver
-
Beuers U, Bilzer M, Chittattu A, Kullak-Ublick GA, Keppler D, Paumgartner G, and Dombrowski F (2001) Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver. Hepatology 33:1206-1216.
-
(2001)
Hepatology
, vol.33
, pp. 1206-1216
-
-
Beuers, U.1
Bilzer, M.2
Chittattu, A.3
Kullak-Ublick, G.A.4
Keppler, D.5
Paumgartner, G.6
Dombrowski, F.7
-
3
-
-
2442700344
-
Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels
-
Buist SC and Klaassen CD (2004) Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels. Drug Metab Dispos 32:620-625.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 620-625
-
-
Buist, S.C.1
Klaassen, C.D.2
-
4
-
-
84860265830
-
IL-6, IL-17 and STAT3: A holy trinity in autoimmunity?
-
Camporeale A and Poli V (2012) IL-6, IL-17 and STAT3: a holy trinity in autoimmunity? Front Biosci (Landmark Ed) 17:2306-2326.
-
(2012)
Front Biosci (Landmark Ed)
, vol.17
, pp. 2306-2326
-
-
Camporeale, A.1
Poli, V.2
-
5
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, and Demengeot J (2003) Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 197:403-411.
-
(2003)
J Exp Med
, vol.197
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
Zelenay, S.4
Haury, M.5
Demengeot, J.6
-
6
-
-
3542995726
-
The complexities of hepatic drug transport: Current knowledge and emerging concepts
-
Chandra P and Brouwer KL (2004) The complexities of hepatic drug transport: current knowledge and emerging concepts. Pharmaceutical Res 21:719-735.
-
(2004)
Pharmaceutical Res
, vol.21
, pp. 719-735
-
-
Chandra, P.1
Brouwer, K.L.2
-
7
-
-
35348997075
-
Regulation of hepatic bile acid transporters Ntcp and Bsep expression
-
Cheng X, Buckley D, and Klaassen CD (2007) Regulation of hepatic bile acid transporters Ntcp and Bsep expression. Biochem Pharmacol 74:1665-1676.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1665-1676
-
-
Cheng, X.1
Buckley, D.2
Klaassen, C.D.3
-
8
-
-
3042599451
-
Lipopolysaccharidemediated regulation of hepatic transporter mRNA levels in rats
-
Cherrington NJ, Slitt AL, Li N, and Klaassen CD (2004) Lipopolysaccharidemediated regulation of hepatic transporter mRNA levels in rats. Drug Metab Dispos 32:734-741.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 734-741
-
-
Cherrington, N.J.1
Slitt, A.L.2
Li, N.3
Klaassen, C.D.4
-
9
-
-
33744497029
-
Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis
-
Clodfelter KH, Holloway MG, Hodor P, Park SH, Ray WJ, and Waxman DJ (2006) Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Mol Endocrinol 20:1333-1351.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 1333-1351
-
-
Clodfelter, K.H.1
Holloway, M.G.2
Hodor, P.3
Park, S.H.4
Ray, W.J.5
Waxman, D.J.6
-
10
-
-
34548813862
-
Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis
-
Clodfelter KH, Miles GD, Wauthier V, Holloway MG, Zhang X, Hodor P, Ray WJ, and Waxman DJ (2007) Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis. Physiol Genomics 31:63-74.
-
(2007)
Physiol Genomics
, vol.31
, pp. 63-74
-
-
Clodfelter, K.H.1
Miles, G.D.2
Wauthier, V.3
Holloway, M.G.4
Zhang, X.5
Hodor, P.6
Ray, W.J.7
Waxman, D.J.8
-
11
-
-
84862692575
-
Migration of lymphocytes into hepatic sinusoids
-
Crispe IN (2012) Migration of lymphocytes into hepatic sinusoids. J Hepatol 57: 218-220.
-
(2012)
J Hepatol
, vol.57
, pp. 218-220
-
-
Crispe, I.N.1
-
12
-
-
35748931783
-
The roles of innate immune cells in liver injury and regeneration
-
Dong Z, Wei H, Sun R, and Tian Z (2007) The roles of innate immune cells in liver injury and regeneration. Cell Mol Immunol 4:241-252.
-
(2007)
Cell Mol Immunol
, vol.4
, pp. 241-252
-
-
Dong, Z.1
Wei, H.2
Sun, R.3
Tian, Z.4
-
13
-
-
79960282665
-
Targeting the diverse immunological functions expressed by hepatic NKT cells
-
Duwaerts CC and Gregory SH (2011) Targeting the diverse immunological functions expressed by hepatic NKT cells. Expert Opin Ther Targets 15:973-988.
-
(2011)
Expert Opin Ther Targets
, vol.15
, pp. 973-988
-
-
Duwaerts, C.C.1
Gregory, S.H.2
-
14
-
-
0033152796
-
Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells
-
Eberl G, Lees R, Smiley ST, Taniguchi M, Grusby MJ, and MacDonald HR (1999) Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells. J Immunol 162:6410-6419.
-
(1999)
J Immunol
, vol.162
, pp. 6410-6419
-
-
Eberl, G.1
Lees, R.2
Smiley, S.T.3
Taniguchi, M.4
Grusby, M.J.5
MacDonald, H.R.6
-
15
-
-
84862067321
-
Effects of aging on mRNA profiles for drug-metabolizing enzymes and transporters in livers of male and female mice
-
Fu ZD, Csanaky IL, and Klaassen CD (2012) Effects of aging on mRNA profiles for drug-metabolizing enzymes and transporters in livers of male and female mice. Drug Metab Dispos 40:1216-1225.
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 1216-1225
-
-
Fu, Z.D.1
Csanaky, I.L.2
Klaassen, C.D.3
-
16
-
-
33749356605
-
Mechanisms of disease: Mechanisms and clinical implications of cholestasis in sepsis
-
Geier A, Fickert P, and Trauner M (2006) Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis. Nat Clin Pract Gastroenterol Hepatol 3:574-585.
-
(2006)
Nat Clin Pract Gastroenterol Hepatol
, vol.3
, pp. 574-585
-
-
Geier, A.1
Fickert, P.2
Trauner, M.3
-
17
-
-
19344371631
-
Intravascular immune surveillance by CXCR61 NKT cells patrolling liver sinusoids
-
Geissmann F, Cameron TO, Sidobre S, Manlongat N, Kronenberg M, Briskin MJ, Dustin ML, and Littman DR (2005) Intravascular immune surveillance by CXCR61 NKT cells patrolling liver sinusoids. PLoS Biol 3:e113.
-
(2005)
PLoS Biol
, vol.3
-
-
Geissmann, F.1
Cameron, T.O.2
Sidobre, S.3
Manlongat, N.4
Kronenberg, M.5
Briskin, M.J.6
Dustin, M.L.7
Littman, D.R.8
-
18
-
-
75749135293
-
Influence of development, HIV infection, and antiretroviral therapies on the gene expression profiles of ABC transporters in human lymphocytes
-
Giraud C, Manceau S, Declèves X, Goffinet F, Morini JP, Chappuy H, Batteux F, Chouzenoux S, Yousif S, and Scherrmann JM, et al. (2010) Influence of development, HIV infection, and antiretroviral therapies on the gene expression profiles of ABC transporters in human lymphocytes. J Clin Pharmacol 50:226-230.
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 226-230
-
-
Giraud, C.1
Manceau, S.2
Declèves, X.3
Goffinet, F.4
Morini, J.P.5
Chappuy, H.6
Batteux, F.7
Chouzenoux, S.8
Yousif, S.9
Scherrmann, J.M.10
-
19
-
-
79958251746
-
New ways to turn on NKT cells
-
Godfrey DI and Rossjohn J (2011) New ways to turn on NKT cells. J Exp Med 208: 1121-1125.
-
(2011)
J Exp Med
, vol.208
, pp. 1121-1125
-
-
Godfrey, D.I.1
Rossjohn, J.2
-
20
-
-
0029886277
-
Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents
-
Green RM, Beier D, and Gollan JL (1996) Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents. Gastroenterology 111: 193-198.
-
(1996)
Gastroenterology
, vol.111
, pp. 193-198
-
-
Green, R.M.1
Beier, D.2
Gollan, J.L.3
-
21
-
-
41149150143
-
Toll-like receptor expression and responsiveness of distinctmurine splenic and mucosal B-cell subsets
-
Gururajan M, Jacob J, and Pulendran B (2007) Toll-like receptor expression and responsiveness of distinctmurine splenic and mucosal B-cell subsets. PLoS ONE 2:e863.
-
(2007)
PLoS ONE
, vol.2
-
-
Gururajan, M.1
Jacob, J.2
Pulendran, B.3
-
22
-
-
84871242500
-
Bile acid transporters and regulatory nuclear receptors in the liver and beyond
-
Halilbasic E, Claudel T, and Trauner M (2013) Bile acid transporters and regulatory nuclear receptors in the liver and beyond. J Hepatol 58:155-168.
-
(2013)
J Hepatol
, vol.58
, pp. 155-168
-
-
Halilbasic, E.1
Claudel, T.2
Trauner, M.3
-
24
-
-
78049486376
-
Pathogenesis of cholestatic liver disease and therapeutic approaches
-
Hirschfield GM, Heathcote EJ, and Gershwin ME (2010) Pathogenesis of cholestatic liver disease and therapeutic approaches. Gastroenterology 139:1481-1496.
-
(2010)
Gastroenterology
, vol.139
, pp. 1481-1496
-
-
Hirschfield, G.M.1
Heathcote, E.J.2
Gershwin, M.E.3
-
25
-
-
0037064539
-
Molecular basis of the cell specificity of cytokine action
-
Ishihara K and Hirano T (2002) Molecular basis of the cell specificity of cytokine action. Biochim Biophys Acta 1592:281-296.
-
(2002)
Biochim Biophys Acta
, vol.1592
, pp. 281-296
-
-
Ishihara, K.1
Hirano, T.2
-
26
-
-
33947145065
-
Biliary secretion and excretion in health and disease: Current concepts
-
Hofmann AF (2007) Biliary secretion and excretion in health and disease: current concepts. Annals of Hepatology 6:15-27.
-
(2007)
Annals of Hepatology
, vol.6
, pp. 15-27
-
-
Hofmann, A.F.1
-
27
-
-
63849295015
-
The enterohepatic circulation of bile acids in mammals: Form and functions
-
Hofmann AF (2009) The enterohepatic circulation of bile acids in mammals: form and functions. Frontiers in Bioscience: A Journal and Virtual Library 14:2584-2598.
-
(2009)
Frontiers in Bioscience: A Journal and Virtual Library
, vol.14
, pp. 2584-2598
-
-
Hofmann, A.F.1
-
28
-
-
80051621753
-
Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis
-
Katz SC, Ryan K, Ahmed N, Plitas G, Chaudhry UI, Kingham TP, Naheed S, Nguyen C, Somasundar P, and Espat NJ, et al. (2011) Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis. J Immunol 187:1150-1156.
-
(2011)
J Immunol
, vol.187
, pp. 1150-1156
-
-
Katz, S.C.1
Ryan, K.2
Ahmed, N.3
Plitas, G.4
Chaudhry, U.I.5
Kingham, T.P.6
Naheed, S.7
Nguyen, C.8
Somasundar, P.9
Espat, N.J.10
-
29
-
-
84866561039
-
Direct engagement of TLR4 in invariant NKT cells regulates immune diseases by differential IL-4 and IFN-g production in mice
-
Kim JH, Kim HS, Kim HY, Oh SJ, and Chung DH (2012) Direct engagement of TLR4 in invariant NKT cells regulates immune diseases by differential IL-4 and IFN-g production in mice. PLoS ONE 7:e45348.
-
(2012)
PLoS ONE
, vol.7
-
-
Kim, J.H.1
Kim, H.S.2
Kim, H.Y.3
Oh, S.J.4
Chung, D.H.5
-
30
-
-
0039849217
-
Intraabdominal sepsis down-regulates transcription of sodium taurocholate cotransporter and multidrug resistance-associated protein in rats
-
Kim PK, Chen J, Andrejko KM, and Deutschman CS (2000) Intraabdominal sepsis down-regulates transcription of sodium taurocholate cotransporter and multidrug resistance-associated protein in rats. Shock 14:176-181.
-
(2000)
Shock
, vol.14
, pp. 176-181
-
-
Kim, P.K.1
Chen, J.2
Andrejko, K.M.3
Deutschman, C.S.4
-
31
-
-
77949398878
-
Xenobiotic, bile acid, and cholesterol transporters: Function and regulation
-
Klaassen CD and Aleksunes LM (2010) Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacol Rev 62:1-96.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 1-96
-
-
Klaassen, C.D.1
Aleksunes, L.M.2
-
32
-
-
16844387413
-
The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury
-
Klein C, Wüstefeld T, Assmus U, Roskams T, Rose-John S, Müller M, Manns MP, Ernst M, and Trautwein C (2005) The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. J Clin Invest 115:860-869.
-
(2005)
J Clin Invest
, vol.115
, pp. 860-869
-
-
Klein, C.1
Wüstefeld, T.2
Assmus, U.3
Roskams, T.4
Rose-John, S.5
Müller, M.6
Manns, M.P.7
Ernst, M.8
Trautwein, C.9
-
33
-
-
84861000288
-
Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity
-
Kong B, Csanaky IL, Aleksunes LM, Patni M, Chen Q, Ma X, Jaeschke H, Weir S, Broward M, and Klaassen CD, et al. (2012) Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity. Toxicol Appl Pharmacol 261:189-195.
-
(2012)
Toxicol Appl Pharmacol
, vol.261
, pp. 189-195
-
-
Kong, B.1
Csanaky, I.L.2
Aleksunes, L.M.3
Patni, M.4
Chen, Q.5
Ma, X.6
Jaeschke, H.7
Weir, S.8
Broward, M.9
Klaassen, C.D.10
-
34
-
-
0032944048
-
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
-
Kubitz R, Wettstein M, Warskulat U, and Häussinger D (1999) Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology 116:401-410.
-
(1999)
Gastroenterology
, vol.116
, pp. 401-410
-
-
Kubitz, R.1
Wettstein, M.2
Warskulat, U.3
Häussinger, D.4
-
35
-
-
78649493404
-
Age and sex dependent changes in liver gene expression during the life cycle of the rat
-
Kwekel JC, Desai VG, Moland CL, Branham WS, and Fuscoe JC (2010) Age and sex dependent changes in liver gene expression during the life cycle of the rat. BMC Genomics 11:675.
-
(2010)
BMC Genomics
, vol.11
, pp. 675
-
-
Kwekel, J.C.1
Desai, V.G.2
Moland, C.L.3
Branham, W.S.4
Fuscoe, J.C.5
-
36
-
-
6944219987
-
Down-regulation of mouse organic anion-transporting polypeptide 4 (Oatp4; Oatp1b2; Slc21a10) mRNA by lipopolysaccharide through the toll-like receptor 4 (TLR4)
-
Li N, Choudhuri S, Cherrington NJ, and Klaassen CD (2004) Down-regulation of mouse organic anion-transporting polypeptide 4 (Oatp4; Oatp1b2; Slc21a10) mRNA by lipopolysaccharide through the toll-like receptor 4 (TLR4). Drug Metab Dispos 32:1265-1271.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1265-1271
-
-
Li, N.1
Choudhuri, S.2
Cherrington, N.J.3
Klaassen, C.D.4
-
37
-
-
12344319175
-
Lipopolysaccharide-induced down-regulation of organic anion transporting polypeptide 4 (Oatp4; Slc21a10) is independent of tumor necrosis factor-alpha, Interleukin-1beta, interleukin-6, or inducible nitric oxide synthase
-
Li N and Klaassen CD (2005) Lipopolysaccharide-induced down-regulation of organic anion transporting polypeptide 4 (Oatp4; Slc21a10) is independent of tumor necrosis factor-alpha, Interleukin-1beta, interleukin-6, or inducible nitric oxide synthase. Toxicol Sci 83:197-203.
-
(2005)
Toxicol Sci
, vol.83
, pp. 197-203
-
-
Li, N.1
Klaassen, C.D.2
-
38
-
-
84872790689
-
Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy
-
Liao W, Lin JX, and Leonard WJ (2013) Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 38:13-25.
-
(2013)
Immunity
, vol.38
, pp. 13-25
-
-
Liao, W.1
Lin, J.X.2
Leonard, W.J.3
-
39
-
-
33847350212
-
Differential regulation of hepatic transporters in the absence of tumor necrosis factor-alpha, interleukin-1beta, interleukin-6, and nuclear factor-kappaB in two models of cholestasis
-
Lickteig AJ, Slitt AL, Arkan MC, Karin M, and Cherrington NJ (2007) Differential regulation of hepatic transporters in the absence of tumor necrosis factor-alpha, interleukin-1beta, interleukin-6, and nuclear factor-kappaB in two models of cholestasis. Drug Metab Dispos 35:402-409.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 402-409
-
-
Lickteig, A.J.1
Slitt, A.L.2
Arkan, M.C.3
Karin, M.4
Cherrington, N.J.5
-
40
-
-
84859968982
-
Critical role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function
-
Lin JX, Li P, Liu D, Jin HT, He J, Ata Ur Rasheed M, Rochman Y, Wang L, Cui K, and Liu C, et al. (2012) Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity 36:586-599.
-
(2012)
Immunity
, vol.36
, pp. 586-599
-
-
Lin, J.X.1
Li, P.2
Liu, D.3
Jin, H.T.4
He, J.5
Ata-Ur-Rasheed, M.6
Rochman, Y.7
Wang, L.8
Cui, K.9
Liu, C.10
-
41
-
-
22344432207
-
Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice
-
Maher JM, Slitt AL, Cherrington NJ, Cheng X, and Klaassen CD (2005) Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice. Drug Metab Dispos 33:947-955.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 947-955
-
-
Maher, J.M.1
Slitt, A.L.2
Cherrington, N.J.3
Cheng, X.4
Klaassen, C.D.5
-
42
-
-
73449143181
-
Effect of bile salts on the DNA and membrane integrity of enteric bacteria
-
Merritt ME and Donaldson JR (2009) Effect of bile salts on the DNA and membrane integrity of enteric bacteria. J Med Microbiol 58:1533-1541.
-
(2009)
J Med Microbiol
, vol.58
, pp. 1533-1541
-
-
Merritt, M.E.1
Donaldson, J.R.2
-
43
-
-
64249093402
-
Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals
-
Meyer-Bahlburg A, Bandaranayake AD, Andrews SF, and Rawlings DJ (2009) Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals. J Immunol 182:4065-4075.
-
(2009)
J Immunol
, vol.182
, pp. 4065-4075
-
-
Meyer-Bahlburg, A.1
Bandaranayake, A.D.2
Andrews, S.F.3
Rawlings, D.J.4
-
44
-
-
63849332390
-
Nuclear receptors: Mediators and modifiers of inflammation-induced cholestasis
-
Mulder J, Karpen SJ, Tietge UJ, and Kuipers F (2009) Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis. Front Biosci (Landmark Ed) 14:2599-2630.
-
(2009)
Front Biosci (Landmark Ed)
, vol.14
, pp. 2599-2630
-
-
Mulder, J.1
Karpen, S.J.2
Tietge, U.J.3
Kuipers, F.4
-
45
-
-
84858754943
-
Immune functioning in non lymphoid organs: The liver
-
Parker GA and Picut CA (2012) Immune functioning in non lymphoid organs: the liver. Toxicol Pathol 40:237-247.
-
(2012)
Toxicol Pathol
, vol.40
, pp. 237-247
-
-
Parker, G.A.1
Picut, C.A.2
-
46
-
-
77950967415
-
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: Relevance to microbial antibody responses
-
Pone EJ, Zan H, Zhang J, Al-Qahtani A, Xu Z, and Casali P (2010) Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses. Crit Rev Immunol 30:1-29.
-
(2010)
Crit Rev Immunol
, vol.30
, pp. 1-29
-
-
Pone, E.J.1
Zan, H.2
Zhang, J.3
Al-Qahtani, A.4
Xu, Z.5
Casali, P.6
-
47
-
-
84864700392
-
Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation
-
Reynolds JM, Martinez GJ, Chung Y, and Dong C (2012) Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation. Proc Natl Acad Sci USA 109:13064-13069.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 13064-13069
-
-
Reynolds, J.M.1
Martinez, G.J.2
Chung, Y.3
Dong, C.4
-
48
-
-
0035348775
-
Bosentan, an endothelin antagonist, augments hepatic graft function by reducing graft circulatory impairment following ischemia/reperfusion injury
-
Ricciardi R, Schaffer BK, Shah SA, Quarfordt SH, Banner BF, Wheeler SM, Donohue SE, Meyers WC, and Chari RS (2001) Bosentan, an endothelin antagonist, augments hepatic graft function by reducing graft circulatory impairment following ischemia/reperfusion injury. J Gastrointest Surg 5:322-329.
-
(2001)
J Gastrointest Surg
, vol.5
, pp. 322-329
-
-
Ricciardi, R.1
Schaffer, B.K.2
Shah, S.A.3
Quarfordt, S.H.4
Banner, B.F.5
Wheeler, S.M.6
Donohue, S.E.7
Meyers, W.C.8
Chari, R.S.9
-
49
-
-
0042428860
-
Effect of glutathione depletion and hydrophilic bile acids on hepatic acute phase reaction in rats with extrahepatic cholestasis
-
Roeb E, Purucker E, Gartung C, Geier A, Jansen B, Winograd R, and Matern S (2003) Effect of glutathione depletion and hydrophilic bile acids on hepatic acute phase reaction in rats with extrahepatic cholestasis. Scand J Gastroenterol 38: 878-885.
-
(2003)
Scand J Gastroenterol
, vol.38
, pp. 878-885
-
-
Roeb, E.1
Purucker, E.2
Gartung, C.3
Geier, A.4
Jansen, B.5
Winograd, R.6
Matern, S.7
-
51
-
-
0026712313
-
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD41 T cells from T cell receptor transgenic mice
-
Seder RA, Paul WE, Davis MM, and Fazekas de St Groth B (1992) The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD41 T cells from T cell receptor transgenic mice. J Exp Med 176: 1091-1098.
-
(1992)
J Exp Med
, vol.176
, pp. 1091-1098
-
-
Seder, R.A.1
Paul, W.E.2
Davis, M.M.3
Fazekas De-St-Groth, B.4
-
52
-
-
38349085099
-
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
-
Shu Y, Brown C, Castro RA, Shi RJ, Lin ET, Owen RP, Sheardown SA, Yue L, Burchard EG, and Brett CM, et al. (2008) Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. Clin Pharmacol Ther 83:273-280.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 273-280
-
-
Shu, Y.1
Brown, C.2
Castro, R.A.3
Shi, R.J.4
Lin, E.T.5
Owen, R.P.6
Sheardown, S.A.7
Yue, L.8
Burchard, E.G.9
Brett, C.M.10
-
53
-
-
0043167910
-
Lack of gp130 expression in hepatocytes promotes liver injury
-
Streetz KL, Wüstefeld T, Klein C, Kallen KJ, Tronche F, Betz UA, Schütz G, Manns MP, Müller W, and Trautwein C (2003) Lack of gp130 expression in hepatocytes promotes liver injury. Gastroenterology 125:532-543.
-
(2003)
Gastroenterology
, vol.125
, pp. 532-543
-
-
Streetz, K.L.1
Wüstefeld, T.2
Klein, C.3
Kallen, K.J.4
Tronche, F.5
Betz, U.A.6
Schütz, G.7
Manns, M.P.8
Müller, W.9
Trautwein, C.10
-
54
-
-
2142764513
-
IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD41 T cell- and STAT3-dependent manners
-
Sun R, Tian Z, Kulkarni S, and Gao B (2004) IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD41 T cell- and STAT3-dependent manners. J Immunol 172:5648-5655.
-
(2004)
J Immunol
, vol.172
, pp. 5648-5655
-
-
Sun, R.1
Tian, Z.2
Kulkarni, S.3
Gao, B.4
-
55
-
-
1342344700
-
Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes
-
Sunman JA, Hawke RL, LeCluyse EL, and Kashuba AD (2004) Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes. Drug Metab Dispos 32: 359-363.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 359-363
-
-
Sunman, J.A.1
Hawke, R.L.2
Lecluyse, E.L.3
Kashuba, A.D.4
-
56
-
-
85047689502
-
Hepatoprotection via the IL-6/Stat3 pathway
-
Taub R (2003) Hepatoprotection via the IL-6/Stat3 pathway. J Clin Invest 112: 978-980.
-
(2003)
J Clin Invest
, vol.112
, pp. 978-980
-
-
Taub, R.1
-
57
-
-
21344439074
-
Nuclear receptors and drug disposition gene regulation
-
Tirona RG and Kim RB (2005) Nuclear receptors and drug disposition gene regulation. J Pharm Sci 94:1169-1186.
-
(2005)
J Pharm Sci
, vol.94
, pp. 1169-1186
-
-
Tirona, R.G.1
Kim, R.B.2
-
58
-
-
0030918819
-
T cell stimulation in vivo by lipopolysaccharide (LPS)
-
Tough DF, Sun S, and Sprent J (1997) T cell stimulation in vivo by lipopolysaccharide (LPS). J Exp Med 185:2089-2094.
-
(1997)
J Exp Med
, vol.185
, pp. 2089-2094
-
-
Tough, D.F.1
Sun, S.2
Sprent, J.3
-
59
-
-
0037379362
-
Bile salt transporters: Molecular characterization, function, and regulation
-
Trauner M and Boyer JL (2003) Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev 83:633-671.
-
(2003)
Physiol Rev
, vol.83
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
60
-
-
70350733785
-
ABC drug transporters and immunity: Novel therapeutic targets in autoimmunity and cancer
-
van de Ven R, Oerlemans R, van der Heijden JW, Scheffer GL, de Gruijl TD, Jansen G, and Scheper RJ (2009) ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer. J Leukoc Biol 86:1075-1087.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1075-1087
-
-
Van De-Ven, R.1
Oerlemans, R.2
Van Der-Heijden, J.W.3
Scheffer, G.L.4
De Gruijl, T.D.5
Jansen, G.6
Scheper, R.J.7
-
61
-
-
84858675332
-
Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: Ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with rheumatoid arthritis
-
Verbrugge SE, Assaraf YG, Dijkmans BA, Scheffer GL, Al M, den Uyl D, Oerlemans R, Chan ET, Kirk CJ, and Peters GJ, et al. (2012) Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with rheumatoid arthritis. J Pharmacol Exp Ther 341:174-182.
-
(2012)
J Pharmacol Exp Ther
, vol.341
, pp. 174-182
-
-
Verbrugge, S.E.1
Assaraf, Y.G.2
Dijkmans, B.A.3
Scheffer, G.L.4
Al, M.5
Den Uyl, D.6
Oerlemans, R.7
Chan, E.T.8
Kirk, C.J.9
Peters, G.J.10
-
62
-
-
84863011066
-
Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver
-
Zhang Y, Laz EV, and Waxman DJ (2012) Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver. Mol Cell Biol 32:880-896.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 880-896
-
-
Zhang, Y.1
Laz, E.V.2
Waxman, D.J.3
|