-
1
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocrine Reviews 20 1999 649 688 (Pubitemid 30650602)
-
(1999)
Endocrine Reviews
, vol.20
, Issue.5
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
2
-
-
77954987061
-
PPARalpha: Energy combustion, hypolipidemia, inflammation and cancer
-
S.R. Pyper, N. Viswakarma, S. Yu, and J.K. Reddy PPARalpha: energy combustion, hypolipidemia, inflammation and cancer Nuclear Receptor Signaling 8 2010 e002
-
(2010)
Nuclear Receptor Signaling
, vol.8
, pp. 002
-
-
Pyper, S.R.1
Viswakarma, N.2
Yu, S.3
Reddy, J.K.4
-
3
-
-
34447618831
-
PPARs and their metabolic modulation: New mechanisms for transcriptional regulation?
-
DOI 10.1111/j.1365-2796.2007.01825.x
-
W. Ahmed, O. Ziouzenkova, J. Brown, P. Devchand, and S. Francis PPARs and their metabolic modulation: new mechanisms for transcriptional regulation? Journal of Internal Medicine 262 2007 184 198 (Pubitemid 47087629)
-
(2007)
Journal of Internal Medicine
, vol.262
, Issue.2
, pp. 184-198
-
-
Ahmed, W.1
Ziouzenkova, O.2
Brown, J.3
Devchand, P.4
Francis, S.5
Kadakia, M.6
Kanda, T.7
Orasanu, G.8
Sharlach, M.9
Zandbergen, F.10
Plutzky, J.11
-
4
-
-
33645112691
-
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)
-
M.A. Peraza, A.D. Burdick, H.E. Marin, F.J. Gonzalez, and J.M. Peters The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR) Toxicological Sciences 90 2006 269 295
-
(2006)
Toxicological Sciences
, vol.90
, pp. 269-295
-
-
Peraza, M.A.1
Burdick, A.D.2
Marin, H.E.3
Gonzalez, F.J.4
Peters, J.M.5
-
5
-
-
18044376795
-
PPARs: Therapeutic targets for metabolic disease
-
DOI 10.1016/j.tips.2005.03.003
-
J.P. Berger, T.E. Akiyama, and P.T. Meinke PPARs: therapeutic targets for metabolic disease Trends in Pharmacological Sciences 26 2005 244 251 (Pubitemid 40603072)
-
(2005)
Trends in Pharmacological Sciences
, vol.26
, Issue.5
, pp. 244-251
-
-
Berger, J.P.1
Akiyama, T.E.2
Meinke, P.T.3
-
6
-
-
77951457202
-
Fibrates, glitazones, and peroxisome proliferator-activated receptors
-
F. Lalloyer, and B. Staels Fibrates, glitazones, and peroxisome proliferator-activated receptors Arteriosclerosis, Thrombosis, and Vascular Biology 30 2010 894 899
-
(2010)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.30
, pp. 894-899
-
-
Lalloyer, F.1
Staels, B.2
-
7
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: No alteration in adipose tissue of obese and NIDDM patients
-
D. Auboeuf, J. Rieusset, L. Fajas, P. Vallier, and V. Frering Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients Diabetes 46 1997 1319 1327 (Pubitemid 27315281)
-
(1997)
Diabetes
, vol.46
, Issue.8
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
8
-
-
0000637396
-
Modification of metabolism and distribution of lipids by ethyl chlorophenoxyisobutyrate
-
J.M. Thorp, and W.S. Waring Modification of metabolism and distribution of lipids by ethyl chlorophenoxyisobutyrate Nature 194 1962 948 949
-
(1962)
Nature
, vol.194
, pp. 948-949
-
-
Thorp, J.M.1
Waring, W.S.2
-
9
-
-
0018888058
-
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
-
J.K. Reddy, D.L. Azarnoff, and C.E. Hignite Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens Nature 283 1980 397 398 (Pubitemid 10125816)
-
(1980)
Nature
, vol.283
, Issue.5745
, pp. 397-398
-
-
Reddy, J.K.1
Azarnoff, D.L.2
Hignite, C.E.3
-
10
-
-
79952851918
-
Use of fibrates in the United States and Canada
-
C.A. Jackevicius, J.V. Tu, J.S. Ross, D.T. Ko, and D. Carreon Use of fibrates in the United States and Canada JAMA 305 2011 1217 1224
-
(2011)
JAMA
, vol.305
, pp. 1217-1224
-
-
Jackevicius, C.A.1
Tu, J.V.2
Ross, J.S.3
Ko, D.T.4
Carreon, D.5
-
11
-
-
0028997684
-
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
S.S. Lee, T. Pineau, J. Drago, E.J. Lee, and J.W. Owens Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators Molecular and Cellular Biology 15 1995 3012 3022
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
-
12
-
-
0031418657
-
Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
-
DOI 10.1093/carcin/18.11.2029
-
J.M. Peters, R.C. Cattley, and F.J. Gonzalez Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643 Carcinogenesis 18 1997 2029 2033 (Pubitemid 28134725)
-
(1997)
Carcinogenesis
, vol.18
, Issue.11
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
14
-
-
0028172089
-
Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis
-
J. Ashby, A. Brady, C.R. Elcombe, B.M. Elliott, and J. Ishmael Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis Human and Experimental Toxicology 13 Suppl. 2 1994 S1 S117
-
(1994)
Human and Experimental Toxicology
, vol.13
, Issue.SUPPL. 2
-
-
Ashby, J.1
Brady, A.2
Elcombe, C.R.3
Elliott, B.M.4
Ishmael, J.5
-
15
-
-
0031838516
-
Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans?
-
DOI 10.1006/rtph.1997.1163
-
R.C. Cattley, J. DeLuca, C. Elcombe, P. Fenner-Crisp, and B.G. Lake Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans? Regulatory Toxicology and Pharmacology 27 1998 47 60 (Pubitemid 28289021)
-
(1998)
Regulatory Toxicology and Pharmacology
, vol.27
, Issue.1
, pp. 47-60
-
-
Cattley, R.C.1
DeLuca, J.2
Elcombe, C.3
Fenner-Crisp, P.4
Lake, B.G.5
Marsman, D.S.6
Pastoor, T.A.7
Popp, J.A.8
Robinson, D.E.9
Schwetz, A.B.10
Tugwood, J.11
Wahli, W.12
-
16
-
-
2542635631
-
Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor α
-
DOI 10.1158/0008-5472.CAN-04-0322
-
C. Cheung, T.E. Akiyama, J.M. Ward, C.J. Nicol, and L. Feigenbaum Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha Cancer Research 64 2004 3849 3854 (Pubitemid 38697295)
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 3849-3854
-
-
Cheung, C.1
Akiyama, T.E.2
Ward, J.M.3
Nicol, C.J.4
Feigenbaum, L.5
Vinson, C.6
Gonzalez, F.J.7
-
17
-
-
33646180263
-
Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis
-
K. Morimura, C. Cheung, J.M. Ward, J.K. Reddy, and F.J. Gonzalez Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis Carcinogenesis 27 2006 1074 1080
-
(2006)
Carcinogenesis
, vol.27
, pp. 1074-1080
-
-
Morimura, K.1
Cheung, C.2
Ward, J.M.3
Reddy, J.K.4
Gonzalez, F.J.5
-
18
-
-
0030454445
-
Peroxisome proliferator-activated receptors: Stuctures and function
-
DOI 10.1111/j.1749-6632.1996.tb18620.x
-
J.D. Tugwood, T.C. Aldridge, K.G. Lambe, N. Macdonald, and N.J. Woodyatt Peroxisome proliferator-activated receptors: structures and function Annals of the New York Academy of Sciences 804 1996 252 265 (Pubitemid 27056614)
-
(1996)
Annals of the New York Academy of Sciences
, vol.804
, pp. 252-265
-
-
Tugwood, J.D.1
Aldridge, T.C.2
Lambe, K.G.3
Macdonald, N.4
Woodyatt, N.J.5
-
19
-
-
0031952238
-
Peroxisome proliferator activated receptor-α expression in human liver
-
C.N. Palmer, M.H. Hsu, K.J. Griffin, J.L. Raucy, and E.F. Johnson Peroxisome proliferator activated receptor-alpha expression in human liver Molecular Pharmacology 53 1998 14 22 (Pubitemid 28068368)
-
(1998)
Molecular Pharmacology
, vol.53
, Issue.1
, pp. 14-22
-
-
Palmer, C.N.A.1
Hsu, M.-H.2
Griffin, K.J.3
Raucy, J.L.4
Johnson, E.F.5
-
20
-
-
34547604561
-
Transcription coactivators for peroxisome proliferator-activated receptors
-
DOI 10.1016/j.bbalip.2007.01.008, PII S138819810700011X
-
S. Yu, and J.K. Reddy Transcription coactivators for peroxisome proliferator-activated receptors Biochimica et Biophysica Acta 1771 2007 936 951 (Pubitemid 47198542)
-
(2007)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1771
, Issue.8
, pp. 936-951
-
-
Yu, S.1
Reddy, J.K.2
-
21
-
-
2342428577
-
Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes
-
DOI 10.1093/toxsci/kfh071
-
M. Ammerschlaeger, J. Beigel, K.U. Klein, and S.O. Mueller Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes Toxicological Sciences 78 2004 229 240 (Pubitemid 38559671)
-
(2004)
Toxicological Sciences
, vol.78
, Issue.2
, pp. 229-240
-
-
Ammerschlaeger, M.1
Beigel, J.2
Klein, K.-U.3
Mueller, S.O.4
-
22
-
-
27644452273
-
Differential responses of PPARα, PPARδ, and PPARγ reporter cell lines to selective PPAR synthetic ligands
-
DOI 10.1016/j.ab.2005.06.010
-
M. Seimandi, G. Lemaire, A. Pillon, A. Perrin, and I. Carlavan Differential responses of PPARalpha, PPARdelta, and PPARgamma reporter cell lines to selective PPAR synthetic ligands Analytical Biochemistry 344 2005 8 15 (Pubitemid 41569372)
-
(2005)
Analytical Biochemistry
, vol.344
, Issue.1
, pp. 8-15
-
-
Seimandi, M.1
Lemaire, G.2
Pillon, A.3
Perrin, A.4
Carlavan, I.5
Voegel, J.J.6
Vignon, F.7
Nicolas, J.-C.8
Balaguer, P.9
-
23
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
K. Yu, W. Bayona, C.B. Kallen, H.P. Harding, and C.P. Ravera Differential activation of peroxisome proliferator-activated receptors by eicosanoids Journal of Biological Chemistry 270 1995 23975 23983
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
Harding, H.P.4
Ravera, C.P.5
-
24
-
-
71049164157
-
Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells
-
S. Kim, E. Dere, L.D. Burgoon, C.C. Chang, and T.R. Zacharewski Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells Toxicological Sciences 112 2009 229 244
-
(2009)
Toxicological Sciences
, vol.112
, pp. 229-244
-
-
Kim, S.1
Dere, E.2
Burgoon, L.D.3
Chang, C.C.4
Zacharewski, T.R.5
-
25
-
-
13844283359
-
Expression of Oct-4, alpha fetoprotein and vimentin and lack of gap-junctional intercellular communication (GJIC) as common phenotypes for human adult liver stem cells and hepatoma cells
-
C.C. Chang, J.L. Tsai, K.K. Kuo, K.H. Wang, and C.H. Chiang Expression of Oct-4, alpha fetoprotein and vimentin and lack of gap-junctional intercellular communication (GJIC) as common phenotypes for human adult liver stem cells and hepatoma cells Proceedings of the American Association for Cancer Research 45 2004 642
-
(2004)
Proceedings of the American Association for Cancer Research
, vol.45
, pp. 642
-
-
Chang, C.C.1
Tsai, J.L.2
Kuo, K.K.3
Wang, K.H.4
Chiang, C.H.5
-
26
-
-
22244433866
-
- cancer cells are similarly tumorigenic
-
DOI 10.1158/0008-5472.CAN-05-0592
-
L. Patrawala, T. Calhoun, R. Schneider-Broussard, J. Zhou, and K. Claypool Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic Cancer Research 65 2005 6207 6219 (Pubitemid 40994406)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
27
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
J.E. Visvader, and G.J. Lindeman Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nature Reviews Cancer 8 2008 755 768
-
(2008)
Nature Reviews Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
28
-
-
58449135983
-
Stem cells in liver regeneration, fibrosis and cancer: The good, the bad and the ugly
-
M.R. Alison, S. Islam, and S. Lim Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly Journal of Pathology 217 2009 282 298
-
(2009)
Journal of Pathology
, vol.217
, pp. 282-298
-
-
Alison, M.R.1
Islam, S.2
Lim, S.3
-
29
-
-
73349143317
-
PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol
-
C. Crisafulli, S. Bruscoli, E. Esposito, E. Mazzon, and R. Di Paola PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol Journal of Pharmacology and Experimental Therapeutics 331 2009 796 807
-
(2009)
Journal of Pharmacology and Experimental Therapeutics
, vol.331
, pp. 796-807
-
-
Crisafulli, C.1
Bruscoli, S.2
Esposito, E.3
Mazzon, E.4
Di Paola, R.5
-
30
-
-
20544460373
-
Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-mediated hepatotoxicity
-
DOI 10.1093/toxsci/kfi162
-
D.R. Boverhof, L.D. Burgoon, C. Tashiro, B. Chittim, and J.R. Harkema Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-mediated hepatotoxicity Toxicological Sciences 85 2005 1048 1063 (Pubitemid 40846879)
-
(2005)
Toxicological Sciences
, vol.85
, Issue.2
, pp. 1048-1063
-
-
Boverhof, D.R.1
Burgoon, L.D.2
Tashiro, C.3
Chittim, B.4
Harkema, J.R.5
Jump, D.B.6
Zacharewski, T.R.7
-
31
-
-
39149094621
-
Comparative toxicogenomic examination of the hepatic effects of PCB126 and TCDD in immature, ovariectomized C57BL/6 mice
-
DOI 10.1093/toxsci/kfm289
-
A.K. Kopec, D.R. Boverhof, L.D. Burgoon, D. Ibrahim-Aibo, and J.R. Harkema Comparative toxicogenomic examination of the hepatic effects of PCB126 and TCDD in immature, ovariectomized C57BL/6 mice Toxicological Sciences 102 2008 61 75 (Pubitemid 351250469)
-
(2008)
Toxicological Sciences
, vol.102
, Issue.1
, pp. 61-75
-
-
Kopec, A.K.1
Boverhof, D.R.2
Burgoon, L.D.3
Ibrahim-Aibo, D.4
Harkema, J.R.5
Tashiro, C.6
Chittim, B.7
Zacharewski, T.R.8
-
32
-
-
77049107075
-
PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: Comparative toxicogenomic effects of dioxin and non-dioxin-like ligands
-
A.K. Kopec, L.D. Burgoon, D. Ibrahim-Aibo, B.D. Mets, and C. Tashiro PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: comparative toxicogenomic effects of dioxin and non-dioxin-like ligands Toxicology and Applied Pharmacology 243 2010 359 371
-
(2010)
Toxicology and Applied Pharmacology
, vol.243
, pp. 359-371
-
-
Kopec, A.K.1
Burgoon, L.D.2
Ibrahim-Aibo, D.3
Mets, B.D.4
Tashiro, C.5
-
33
-
-
77958483338
-
Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice
-
A.K. Kopec, L.D. Burgoon, D. Ibrahim-Aibo, A.R. Burg, and A.W. Lee Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice Toxicological Sciences 118 2010 286 297
-
(2010)
Toxicological Sciences
, vol.118
, pp. 286-297
-
-
Kopec, A.K.1
Burgoon, L.D.2
Ibrahim-Aibo, D.3
Burg, A.R.4
Lee, A.W.5
-
34
-
-
9844227351
-
Cytotoxic effects of acrylates and methacrylates: Relationships of monomer structures and cytotoxicity
-
E. Yoshii Cytotoxic effects of acrylates and methacrylates: relationships of monomer structures and cytotoxicity Journal of Biomedical Materials Research 37 1997 517 524 (Pubitemid 27514859)
-
(1997)
Journal of Biomedical Materials Research
, vol.37
, Issue.4
, pp. 517-524
-
-
Yoshii, E.1
-
35
-
-
16344379368
-
Normalization of two-channel microarray experiments: A semiparametic approach
-
DOI 10.1093/bioinformatics/bti105
-
J.E. Eckel, C. Gennings, T.M. Therneau, L.D. Burgoon, and D.R. Boverhof Normalization of two-channel microarray experiments: a semiparametric approach Bioinformatics 21 2005 1078 1083 (Pubitemid 40467931)
-
(2005)
Bioinformatics
, vol.21
, Issue.7
, pp. 1078-1083
-
-
Eckel, J.E.1
Gennings, C.2
Therneau, T.M.3
Burgoon, L.D.4
Boverhof, D.R.5
Zacharewski, T.R.6
-
36
-
-
4644240907
-
Empirical bayes gene screening tool for time-course or dose-response microarray data
-
DOI 10.1081/BIP-200025656
-
J.E. Eckel, C. Gennings, V.M. Chinchilli, L.D. Burgoon, and T.R. Zacharewski Empirical Bayes gene screening tool for time-course or dose-response microarray data Journal of Biopharmaceutical Statistics 14 2004 647 670 (Pubitemid 39296091)
-
(2004)
Journal of Biopharmaceutical Statistics
, vol.14
, Issue.3
, pp. 647-670
-
-
Eckel, J.E.1
Gennings, C.2
Chinchilli, V.M.3
Burgoon, L.D.4
Zacharewski, T.R.5
-
37
-
-
33947604175
-
DbZach toxicogenomic information management system
-
DOI 10.2217/14622416.8.3.287
-
L.D. Burgoon, and T.R. Zacharewski dbZach toxicogenomic information management system Pharmacogenomics 8 2007 287 291 (Pubitemid 46477740)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.3
, pp. 287-291
-
-
Burgoon, L.D.1
Zacharewski, T.R.2
-
38
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
A.I. Saeed, V. Sharov, J. White, J. Li, and W. Liang TM4: a free, open-source system for microarray data management and analysis Biotechniques 34 2003 374 378 (Pubitemid 36184095)
-
(2003)
BioTechniques
, vol.34
, Issue.2
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
Li, J.4
Liang, W.5
Bhagabati, N.6
Braisted, J.7
Klapa, M.8
Currier, T.9
Thiagarajan, M.10
Sturn, A.11
Snuffin, M.12
Rezantsev, A.13
Popov, D.14
Ryltsov, A.15
Kostukovich, E.16
Borisovsky, I.17
Liu, Z.18
Vinsavich, A.19
Trush, V.20
Quackenbush, J.21
more..
-
39
-
-
0038005018
-
DAVID: Database for Annotation, Visualization, and Integrated Discovery
-
G. Dennis Jr., B.T. Sherman, D.A. Hosack, J. Yang, and W. Gao DAVID: Database for Annotation, Visualization, and Integrated Discovery Genome Biology 4 2003 P3
-
(2003)
Genome Biology
, vol.4
, pp. 3
-
-
Dennis, Jr.G.1
Sherman, B.T.2
Hosack, D.A.3
Yang, J.4
Gao, W.5
-
40
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
S. Rozen, and H. Skaletsky Primer3 on the WWW for general users and for biologist programmers Methods in Molecular Biology 132 2000 365 386
-
(2000)
Methods in Molecular Biology
, vol.132
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.2
-
41
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, and N. Van Roy Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biology 3 2002 RESEARCH0034
-
(2002)
Genome Biology
, vol.3
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
-
42
-
-
0037095769
-
Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays
-
T. Yuen, E. Wurmbach, R.L. Pfeffer, B.J. Ebersole, and S.C. Sealfon Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays Nucleic Acids Research 30 2002 e48
-
(2002)
Nucleic Acids Research
, vol.30
, pp. 48
-
-
Yuen, T.1
Wurmbach, E.2
Pfeffer, R.L.3
Ebersole, B.J.4
Sealfon, S.C.5
-
43
-
-
0018345144
-
Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643), in rat and mouse liver
-
J.K. Reddy, M.S. Rao, D.L. Azarnoff, and S. Sell Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643), in rat and mouse liver Cancer Research 39 1979 152 161 (Pubitemid 9090427)
-
(1979)
Cancer Research
, vol.39
, Issue.1
, pp. 152-161
-
-
Reddy, J.K.1
Sambasiva Rao, M.2
Azarnoff, D.L.3
Sell, S.4
-
44
-
-
77953023029
-
Evaluation of in vivo liver genotoxic potential of Wy-14,643 and piperonyl butoxide in rats subjected to two-week repeated oral administration
-
T. Suzuki, M. Jin, Y. Dewa, R. Ichimura, and Y. Shimada Evaluation of in vivo liver genotoxic potential of Wy-14,643 and piperonyl butoxide in rats subjected to two-week repeated oral administration Archives of Toxicology 84 2010 493 500
-
(2010)
Archives of Toxicology
, vol.84
, pp. 493-500
-
-
Suzuki, T.1
Jin, M.2
Dewa, Y.3
Ichimura, R.4
Shimada, Y.5
-
45
-
-
0022397282
-
Disposition, metabolism and pharmacokinetics of antihyperlipidemic agents in laboratory animals and man
-
DOI 10.1016/0163-7258(85)90028-2
-
M.N. Cayen Disposition, metabolism and pharmacokinetics of antihyperlipidemic agents in laboratory animals and man Pharmacology and Therapeutics 29 1985 157 204 (Pubitemid 16168250)
-
(1985)
Pharmacology and Therapeutics
, vol.29
, Issue.2
, pp. 157-204
-
-
Cayen, M.N.1
-
47
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
DOI 10.1021/jm990554g
-
T.M. Willson, P.J. Brown, D.D. Sternbach, and B.R. Henke The PPARs: from orphan receptors to drug discovery Journal of Medicinal Chemistry 43 2000 527 550 (Pubitemid 30127149)
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.4
, pp. 527-550
-
-
Willson, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
48
-
-
0346156024
-
PPARα Agonist-Induced Rodent Tumors: Modes of Action and Human Relevance
-
J.E. Klaunig, M.A. Babich, K.P. Baetcke, J.C. Cook, and J.C. Corton PPARalpha agonist-induced rodent tumors: modes of action and human relevance Critical Reviews in Toxicology 33 2003 655 780 (Pubitemid 38037444)
-
(2003)
Critical Reviews in Toxicology
, vol.33
, Issue.6
, pp. 655-780
-
-
Klaunig, J.E.1
Babich, M.A.2
Baetcke, K.P.3
Cook, J.C.4
Corton, J.C.5
David, R.M.6
DeLuca, J.G.7
Lai, D.Y.8
McKee, R.H.9
Peters, J.M.10
Roberts, R.A.11
Fenner-Crisp, P.A.12
-
49
-
-
0037020156
-
Peroxisome proliferator-activated receptor alpha (PPARalpha) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes
-
C. Blanquart, O. Barbier, J.C. Fruchart, B. Staels, and C. Glineur Peroxisome proliferator-activated receptor alpha (PPARalpha) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes Journal of Biological Chemistry 277 2002 37254 37259
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 37254-37259
-
-
Blanquart, C.1
Barbier, O.2
Fruchart, J.C.3
Staels, B.4
Glineur, C.5
-
50
-
-
79952204238
-
Regulation of proteome maintenance gene expression by activators of peroxisome proliferator-activated receptor alpha
-
H. Ren, B. Vallanat, H.M. Brown-Borg, R. Currie, and J.C. Corton Regulation of proteome maintenance gene expression by activators of peroxisome proliferator-activated receptor alpha PPAR Research 2010 727194
-
(2010)
PPAR Research
, pp. 727194
-
-
Ren, H.1
Vallanat, B.2
Brown-Borg, H.M.3
Currie, R.4
Corton, J.C.5
-
51
-
-
10844247029
-
The transcriptional response to a peroxisome proliferator-activated receptor α agonist includes increased expression of proteome maintenance genes
-
DOI 10.1074/jbc.M409347200
-
S.P. Anderson, P. Howroyd, J. Liu, X. Qian, and R. Bahnemann The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes Journal of Biological Chemistry 279 2004 52390 52398 (Pubitemid 39662730)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 52390-52398
-
-
Anderson, S.P.1
Howroyd, P.2
Liu, J.3
Qian, X.4
Bahnemann, R.5
Swanson, C.6
Kwak, M.-K.7
Kensler, T.W.8
Corton, J.C.9
-
52
-
-
0037195136
-
PI31 is a modulator of proteasome formation and antigen processing
-
DOI 10.1073/pnas.212257299
-
D.M. Zaiss, S. Standera, P.M. Kloetzel, and A.J. Sijts PI31 is a modulator of proteasome formation and antigen processing Proceedings of the National Academy of Sciences of the United States of America 99 2002 14344 14349 (Pubitemid 35257674)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.22
, pp. 14344-14349
-
-
Zaiss, D.M.W.1
Standera, S.2
Kloetzel, P.-M.3
Sijts, A.J.A.M.4
-
53
-
-
76949105688
-
Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha)
-
B. Vallanat, S.P. Anderson, H.M. Brown-Borg, H. Ren, and S. Kersten Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) BMC Genomics 11 2010 16
-
(2010)
BMC Genomics
, vol.11
, pp. 16
-
-
Vallanat, B.1
Anderson, S.P.2
Brown-Borg, H.M.3
Ren, H.4
Kersten, S.5
-
54
-
-
78549248181
-
PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells
-
A. Qu, Y.M. Shah, T. Matsubara, Q. Yang, and F.J. Gonzalez PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells Toxicological Sciences 118 2010 404 410
-
(2010)
Toxicological Sciences
, vol.118
, pp. 404-410
-
-
Qu, A.1
Shah, Y.M.2
Matsubara, T.3
Yang, Q.4
Gonzalez, F.J.5
-
55
-
-
27644519691
-
Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver
-
DOI 10.1093/toxsci/kfi273
-
N.F. Cariello, E.H. Romach, H.M. Colton, H. Ni, and L. Yoon Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver Toxicological Sciences 88 2005 250 264 (Pubitemid 41548767)
-
(2005)
Toxicological Sciences
, vol.88
, Issue.1
, pp. 250-264
-
-
Cariello, N.F.1
Romach, E.H.2
Colton, H.M.3
Ni, H.4
Yoon, L.5
Falls, J.G.6
Casey, W.7
Creech, D.8
Anderson, S.P.9
Benavides, G.R.10
Hoivik, D.J.11
Brown, R.12
Miller, R.T.13
-
56
-
-
0042305464
-
Transcription profiling distinguishes dose-dependent effects in the livers of rats treated with clofibrate
-
DOI 10.1080/01926230309726
-
J.A. Kramer, E.A. Blomme, R.T. Bunch, J.C. Davila, and C.J. Jackson Transcription profiling distinguishes dose-dependent effects in the livers of rats treated with clofibrate Toxicologic Pathology 31 2003 417 431 (Pubitemid 36897238)
-
(2003)
Toxicologic Pathology
, vol.31
, Issue.4
, pp. 417-431
-
-
Kramer, J.A.1
Blomme, E.A.G.2
Bunch, R.T.3
Davila, J.C.4
Jackson, C.J.5
Jones, P.F.6
Kolaja, K.L.7
Curtiss, S.W.8
-
57
-
-
56349166510
-
PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways
-
S. Ramanan, M. Kooshki, W. Zhao, F.C. Hsu, and M.E. Robbins PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways Free Radical Biology and Medicine 45 2008 1695 1704
-
(2008)
Free Radical Biology and Medicine
, vol.45
, pp. 1695-1704
-
-
Ramanan, S.1
Kooshki, M.2
Zhao, W.3
Hsu, F.C.4
Robbins, M.E.5
-
58
-
-
0033527569
-
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
-
P. Delerive, K. De Bosscher, S. Besnard, W. Vanden Berghe, and J.M. Peters Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1 Journal of Biological Chemistry 274 1999 32048 32054
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De Bosscher, K.2
Besnard, S.3
Vanden Berghe, W.4
Peters, J.M.5
-
59
-
-
0034711185
-
Induction of IκBα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators
-
DOI 10.1074/jbc.M004045200
-
P. Delerive, P. Gervois, J.C. Fruchart, and B. Staels Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators Journal of Biological Chemistry 275 2000 36703 36707 (Pubitemid 32002075)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 36703-36707
-
-
Delerive, P.1
Gervois, P.2
Fruchart, J.-C.3
Staels, B.4
-
60
-
-
34047187449
-
The Interleukin-1 receptor antagonist is a direct target gene of PPARα in liver
-
DOI 10.1016/j.jhep.2006.11.019, PII S0168827806006726
-
R. Stienstra, S. Mandard, N.S. Tan, W. Wahli, and C. Trautwein The interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver Journal of Hepatology 46 2007 869 877 (Pubitemid 46529035)
-
(2007)
Journal of Hepatology
, vol.46
, Issue.5
, pp. 869-877
-
-
Stienstra, R.1
Mandard, S.2
Tan, N.S.3
Wahli, W.4
Trautwein, C.5
Richardson, T.A.6
Lichtenauer-Kaligis, E.7
Kersten, S.8
Muller, M.9
-
61
-
-
0029661982
-
The PPARalpha-leukotriene B4 pathway to inflammation control
-
P.R. Devchand, H. Keller, J.M. Peters, M. Vazquez, and F.J. Gonzalez The PPARalpha-leukotriene B4 pathway to inflammation control Nature 384 1996 39 43
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vazquez, M.4
Gonzalez, F.J.5
-
62
-
-
2342644813
-
Administration of the Potent PPARα Agonist, Wy-14,643, Reverses Nutritional Fibrosis and Steatohepatitis in Mice
-
DOI 10.1002/hep.20170
-
E. Ip, G. Farrell, P. Hall, G. Robertson, and I. Leclercq Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice Hepatology 39 2004 1286 1296 (Pubitemid 38569050)
-
(2004)
Hepatology
, vol.39
, Issue.5
, pp. 1286-1296
-
-
Ip, E.1
Farrell, G.2
Hall, P.3
Robertson, G.4
Leclercq, I.5
-
63
-
-
0031813989
-
Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb
-
A. Madej, B. Okopien, J. Kowalski, M. Zielinski, and J. Wysocki Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb International Journal of Clinical Pharmacology and Therapeutics 36 1998 345 349 (Pubitemid 28271555)
-
(1998)
International Journal of Clinical Pharmacology and Therapeutics
, vol.36
, Issue.6
, pp. 345-349
-
-
Madej, A.1
Okopien, B.2
Kowalski, J.3
Zielinski, M.4
Wysocki, J.5
Szygula, B.6
Kalina, Z.7
Herman, Z.S.8
-
64
-
-
38749085998
-
A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease
-
DOI 10.1016/j.dld.2007.10.002, PII S1590865807005506
-
C. Fernandez-Miranda, M. Perez-Carreras, F. Colina, G. Lopez-Alonso, and C. Vargas A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease Digestive and Liver Disease 40 2008 200 205 (Pubitemid 351181792)
-
(2008)
Digestive and Liver Disease
, vol.40
, Issue.3
, pp. 200-205
-
-
Fernandez-Miranda, C.1
Perez-Carreras, M.2
Colina, F.3
Lopez-Alonso, G.4
Vargas, C.5
Solis-Herruzo, J.A.6
-
65
-
-
0035943681
-
Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression
-
J.W. Lawrence, Y. Li, S. Chen, J.G. DeLuca, and J.P. Berger Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression Journal of Biological Chemistry 276 2001 31521 31527
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 31521-31527
-
-
Lawrence, J.W.1
Li, Y.2
Chen, S.3
Deluca, J.G.4
Berger, J.P.5
-
66
-
-
40049088000
-
PPARalpha: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators
-
F.J. Gonzalez, and Y.M. Shah PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators Toxicology 246 2008 2 8
-
(2008)
Toxicology
, vol.246
, pp. 2-8
-
-
Gonzalez, F.J.1
Shah, Y.M.2
-
68
-
-
0033304779
-
A truncated human peroxisome proliferator-activated receptor α splice variant with dominant negative activity
-
P. Gervois, I.P. Torra, G. Chinetti, T. Grotzinger, and G. Dubois A truncated human peroxisome proliferator-activated receptor alpha splice variant with dominant negative activity Molecular Endocrinology 13 1999 1535 1549 (Pubitemid 30650594)
-
(1999)
Molecular Endocrinology
, vol.13
, Issue.9
, pp. 1535-1549
-
-
Gervois, P.1
Pineda Torra, I.2
Chinetti, G.3
Grotzinger, T.4
Dubois, G.5
Fruchart, J.-C.6
Fruchart-Najib, J.7
Leitersdorf, E.8
Staels, B.9
-
69
-
-
0030047184
-
Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene
-
DOI 10.1074/jbc.271.4.2147
-
U. Varanasi, R. Chu, Q. Huang, R. Castellon, and A.V. Yeldandi Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene Journal of Biological Chemistry 271 1996 2147 2155 (Pubitemid 26047804)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.4
, pp. 2147-2155
-
-
Varanasi, U.1
Chu, R.2
Huang, Q.3
Castellon, R.4
Yeldandi, A.V.5
Reddy, J.K.6
-
70
-
-
2442696086
-
Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARα-regulated gene expression in liver
-
DOI 10.1074/jbc.M402391200
-
Y. Jia, C. Qi, P. Kashireddi, S. Surapureddi, and Y.J. Zhu Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver Journal of Biological Chemistry 279 2004 24427 24434 (Pubitemid 38725306)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.23
, pp. 24427-24434
-
-
Jia, Y.1
Qi, C.2
Kashireddi, P.3
Surapureddi, S.4
Zhu, Y.-J.5
Rao, M.S.6
Le Roith, D.7
Chambon, P.8
Gonzalez, F.J.9
Reddy, J.K.10
-
71
-
-
34447122582
-
Critical role for transcription coactivator Peroxisome Proliferator- activated Receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARα ligand-induced liver tumor development
-
DOI 10.1074/jbc.M701956200
-
K. Matsumoto, S. Yu, Y. Jia, M.R. Ahmed, and N. Viswakarma Critical role for transcription coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARalpha ligand-induced liver tumor development Journal of Biological Chemistry 282 2007 17053 17060 (Pubitemid 47093249)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.23
, pp. 17053-17060
-
-
Matsumoto, K.1
Yu, S.2
Jia, Y.3
Ahmed, M.R.4
Viswakarma, N.5
Sarkar, J.6
Kashireddy, P.V.7
Rao, M.S.8
Karpus, W.9
Gonzalez, F.J.10
Reddy, J.K.11
-
72
-
-
0031832805
-
Liver cell models in in vitro toxicology
-
A. Guillouzo Liver cell models in in vitro toxicology Environmental Health Perspectives 106 Suppl. 2 1998 511 532 (Pubitemid 28256760)
-
(1998)
Environmental Health Perspectives
, vol.106
, Issue.SUPPL. 2
, pp. 511-532
-
-
Guillouzo, A.1
-
73
-
-
18044373207
-
Fenofibrate induces apoptotic injury in cultured human hepatocytes by inhibiting phosphorylation of Akt
-
DOI 10.1007/s10495-005-0809-3
-
T. Kubota, T. Yano, K. Fujisaki, Y. Itoh, and R. Oishi Fenofibrate induces apoptotic injury in cultured human hepatocytes by inhibiting phosphorylation of Akt Apoptosis 10 2005 349 358 (Pubitemid 40603488)
-
(2005)
Apoptosis
, vol.10
, Issue.2
, pp. 349-358
-
-
Kubota, T.1
Yano, T.2
Fujisaki, K.3
Itoh, Y.4
Oishi, R.5
-
74
-
-
37649029200
-
Involvement of PPARs in cell proliferation and apoptosis in human colon cancer specimens and in normal and cancer cell lines
-
G. Martinasso, M. Oraldi, A. Trombetta, M. Maggiora, and O. Bertetto Involvement of PPARs in cell proliferation and apoptosis in human colon cancer specimens and in normal and cancer cell lines PPAR Research 2007 93416
-
(2007)
PPAR Research
, pp. 93416
-
-
Martinasso, G.1
Oraldi, M.2
Trombetta, A.3
Maggiora, M.4
Bertetto, O.5
-
75
-
-
0035823238
-
Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
-
DOI 10.1126/science.1062257
-
H. Puthalakath, A. Villunger, L.A. O'Reilly, J.G. Beaumont, and L. Coultas Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis Science 293 2001 1829 1832 (Pubitemid 32845780)
-
(2001)
Science
, vol.293
, Issue.5536
, pp. 1829-1832
-
-
Puthalakath, H.1
Villunger, A.2
O'Reilly, L.A.3
Beaumont, J.G.4
Coultas, L.5
Cheney, R.E.6
Huang, D.C.S.7
Strasser, A.8
|